-
1
-
-
0024235996
-
Ifenprodil and SL 82-0715 as cerebral anti-ischemic agents. I. Evidence for efficacy in models of focal cerebral ischemia
-
Gotti, B. et al. Ifenprodil and SL 82.0715 as cerebral anti-ischemic agents. I. Evidence for efficacy in models of focal cerebral ischemia. J. Pharmacol. Exp. Ther. 247, 1211-1221 (1988). (Pubitemid 19022138)
-
(1988)
Journal of Pharmacology and Experimental Therapeutics
, vol.247
, Issue.3
, pp. 1211-1221
-
-
Gotti, B.1
Duverger, D.2
Bertin, J.3
Carter, C.4
Dupont, R.5
Frost, J.6
Gaduilliere, B.7
MacKenzie, E.T.8
Rousseau, J.9
Scatton, B.10
Wick, A.11
-
2
-
-
78649301895
-
NovelN-methyl-D-aspartate receptor antagonists: A review of compounds patented since 2006
-
Koller, M. & Urwyler, S. NovelN-methyl-D-aspartate receptor antagonists: a review of compounds patented since 2006. Expert Opin. Ther. Pat. 20, 1683-1702 (2010).
-
(2010)
Expert Opin. Ther. Pat.
, vol.20
, pp. 1683-1702
-
-
Koller, M.1
Urwyler, S.2
-
3
-
-
77957235696
-
Control of assembly and function of glutamate receptors by the amino-terminal domain
-
Hansen, K. B., Furukawa, H. & Traynelis, S. F. Control of assembly and function of glutamate receptors by the amino-terminal domain. Mol. Pharmacol. 78, 535-549 (2010).
-
(2010)
Mol. Pharmacol.
, vol.78
, pp. 535-549
-
-
Hansen, K.B.1
Furukawa, H.2
Traynelis, S.F.3
-
4
-
-
70350324907
-
Allosteric modulators of NR2BcontainingNMDAreceptors: Molecularmechanismsandtherapeutic potential
-
Mony, L., Kew, J. N., Gunthorpe, M. J. & Paoletti, P. Allosteric modulators of NR2BcontainingNMDAreceptors: molecularmechanismsandtherapeutic potential. Br. J. Pharmacol. 157, 1301-1317 (2009).
-
(2009)
Br. J. Pharmacol.
, vol.157
, pp. 1301-1317
-
-
Mony, L.1
Kew, J.N.2
Gunthorpe, M.J.3
Paoletti, P.4
-
5
-
-
77952363301
-
Glutamate receptor ion channels: Structure, regulation, and function
-
Traynelis, S. F. et al. Glutamate receptor ion channels: structure, regulation, and function. Pharmacol. Rev. 62, 405-496 (2010).
-
(2010)
Pharmacol. Rev.
, vol.62
, pp. 405-496
-
-
Traynelis, S.F.1
-
6
-
-
0029871365
-
Interactions between ifenprodil and the NR2B subunit of the N-methyl-D-aspartate receptor
-
Gallagher, M. J., Huang, H., Pritchett, D. B. & Lynch, D. R. Interactions between ifenprodil and the NR2B subunit of the N-methyl-D-aspartate receptor. J. Biol. Chem. 271, 9603-9611 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 9603-9611
-
-
Gallagher, M.J.1
Huang, H.2
Pritchett, D.B.3
Lynch, D.R.4
-
7
-
-
0027525324
-
Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: Selectivity and mechanisms at recombinant heteromeric receptors
-
Williams, K. Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors. Mol. Pharmacol. 44, 851-859 (1993). (Pubitemid 23317299)
-
(1993)
Molecular Pharmacology
, vol.44
, Issue.4
, pp. 851-859
-
-
Williams, K.1
-
8
-
-
78650818672
-
Cloning and phylogenetic analysis of NMDA receptor subunits NR1 NR2A and NR2B in Xenopus laevis tadpoles
-
Ewald, R. C. & Cline, H. T. Cloning and phylogenetic analysis of NMDA receptor subunits NR1, NR2A and NR2B in Xenopus laevis tadpoles. Front. Mol. Neurosci. 2, 4 (2009).
-
(2009)
Front. Mol. Neurosci.
, vol.2
, pp. 4
-
-
Ewald, R.C.1
Cline, H.T.2
-
9
-
-
68349109621
-
Molecular and functional characterization of Xenopus laevis N-methyl-D-aspartate receptors
-
Schmidt, C. & Hollmann, M. Molecular and functional characterization of Xenopus laevis N-methyl-D-aspartate receptors. Mol. Cell. Neurosci. 42, 116-127 (2009).
-
(2009)
Mol. Cell. Neurosci.
, vol.42
, pp. 116-127
-
-
Schmidt, C.1
Hollmann, M.2
-
10
-
-
72449151659
-
Structure of the zinc-bound aminoterminal domain of the NMDA receptor NR2B subunit
-
Karakas, E., Simorowski, N. & Furukawa, H. Structure of the zinc-bound aminoterminal domain of the NMDA receptor NR2B subunit. EMBO J. 28, 3910-3920 (2009).
-
(2009)
EMBO J.
, vol.28
, pp. 3910-3920
-
-
Karakas, E.1
Simorowski, N.2
Furukawa, H.3
-
11
-
-
67349285101
-
The N-terminal domain of GluR6- subtype glutamate receptor ion channels
-
Kumar, J., Schuck, P., Jin, R. & Mayer, M. L. The N-terminal domain of GluR6- subtype glutamate receptor ion channels. Nature Struct. Mol. Biol. 16, 631-638 (2009).
-
(2009)
Nature Struct. Mol. Biol.
, vol.16
, pp. 631-638
-
-
Kumar, J.1
Schuck, P.2
Jin, R.3
Mayer, M.L.4
-
12
-
-
67649565613
-
Crystal structure and association behaviour of the GluR2 aminoterminal domain
-
Jin, R. et al. Crystal structure and association behaviour of the GluR2 aminoterminal domain. EMBO J. 28, 1812-1823 (2009).
-
(2009)
EMBO J.
, vol.28
, pp. 1812-1823
-
-
Jin, R.1
-
13
-
-
70149087712
-
Crystal structure of the GluR2 amino-terminal domain provides insights into the architecture and assembly of ionotropic glutamate receptors
-
Clayton, A. et al. Crystal structure of the GluR2 amino-terminal domain provides insights into the architecture and assembly of ionotropic glutamate receptors. J. Mol. Biol. 392, 1125-1132 (2009).
-
(2009)
J. Mol. Biol.
, vol.392
, pp. 1125-1132
-
-
Clayton, A.1
-
14
-
-
72049124287
-
X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor
-
Sobolevsky, A. I., Rosconi, M. P. & Gouaux, E. X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor. Nature 462, 745-756 (2009).
-
(2009)
Nature
, vol.462
, pp. 745-756
-
-
Sobolevsky, A.I.1
Rosconi, M.P.2
Gouaux, E.3
-
15
-
-
66649086928
-
Mechanismof differential control of NMDA receptor activity by NR2 subunits
-
Gielen, M., Siegler Retchless, B., Mony, L., Johnson, J. W.&Paoletti, P.Mechanismof differential control of NMDA receptor activity by NR2 subunits. Nature 459, 703-707 (2009).
-
(2009)
Nature
, vol.459
, pp. 703-707
-
-
Gielen, M.1
Siegler Retchless, B.2
Mony, L.3
Johnson, J.W.4
Paoletti, P.5
-
16
-
-
12144257176
-
The micromolar zinc-binding domain on the NMDA receptor subunit NR2B
-
DOI 10.1523/JNEUROSCI.3967-04.2005
-
Rachline, J., Perin-Dureau, F., Le Goff, A., Neyton, J. & Paoletti, P. The micromolar zinc-binding domain on the NMDA receptor subunit NR2B. J. Neurosci. 25, 308-317 (2005). (Pubitemid 40105601)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.2
, pp. 308-317
-
-
Rachline, J.1
Perin-Dureau, F.2
Le Goff, A.3
Neyton, J.4
Paoletti, P.5
-
17
-
-
0344304828
-
Identification of critical residues in theamino terminal domain of the human NR2B subunit involved in the RO 25-6981 binding pocket
-
DOI 10.1124/jpet.103.056291
-
Malherbe, P. et al. Identification of critical residues in theamino terminal domain of the human NR2B subunit involved in the RO 25-6981 binding pocket. J. Pharmacol. Exp. Ther. 307, 897-905 (2003). (Pubitemid 37494206)
-
(2003)
Journal of Pharmacology and Experimental Therapeutics
, vol.307
, Issue.3
, pp. 897-905
-
-
Malherbe, P.1
Mutel, V.2
Broger, C.3
Perin-Dureau, F.4
Kemp, J.A.5
Neyton, J.6
Paoletti, P.7
Kew, J.N.C.8
-
18
-
-
0033051714
-
A regulatory domain (R1-R2) in the amino terminus of the N-methyl-D- aspartate receptor: Effects of spermine, protons, and ifenprodil, and structural similarity to bacterial leucine/isoleucine/valine binding protein
-
Masuko, T. et al. A regulatory domain (R1-R2) in the amino terminus of the N-methyl-D-aspartate receptor: effects of spermine, protons, and ifenprodil, and structural similarity to bacterial leucine/isoleucine/valine binding protein. Mol. Pharmacol. 55, 957-969 (1999). (Pubitemid 29252360)
-
(1999)
Molecular Pharmacology
, vol.55
, Issue.6
, pp. 957-969
-
-
Masuko, T.1
Kashiwagi, K.2
Kuno, T.3
Nguyen, N.D.4
Pahk, A.J.5
Fukuchi, J.-I.6
Igarashi, K.7
Williams, K.8
-
19
-
-
0037101607
-
Mapping the binding site of the neuroprotectant ifenprodil on NMDA receptors
-
Perin-Dureau, F., Rachline, J., Neyton, J. & Paoletti, P. Mapping the binding site of the neuroprotectant ifenprodil on NMDA receptors. J. Neurosci. 22, 5955-5965 (2002). (Pubitemid 35387640)
-
(2002)
Journal of Neuroscience
, vol.22
, Issue.14
, pp. 5955-5965
-
-
Perin-Dureau, F.1
Rachline, J.2
Neyton, J.3
Paoletti, P.4
-
20
-
-
79955525364
-
Amino terminal domains of the NMDA receptor are organized as local heterodimers
-
Lee, C. H. & Gouaux, E. Amino terminal domains of the NMDA receptor are organized as local heterodimers. PLoS ONE 6, e19181 (2011).
-
(2011)
PLoS ONE
, vol.6
-
-
Lee, C.H.1
Gouaux, E.2
-
21
-
-
14244272868
-
PHENIX: Building new software for automated crystallographic structure determination
-
DOI 10.1107/S0907444902016657
-
Adams, P. D. et al. PHENIX: building new software for automated crystallographic structure determination. Acta Crystallogr. D 58, 1948-1954 (2002). (Pubitemid 35337293)
-
(2002)
Acta Crystallographica Section D: Biological Crystallography
, vol.58
, Issue.11
, pp. 1948-1954
-
-
Adams, P.D.1
Grosse-Kunstleve, R.W.2
Hung, L.-W.3
Ioerger, T.R.4
McCoy, A.J.5
Moriarty, N.W.6
Read, R.J.7
Sacchettini, J.C.8
Sauter, N.K.9
Terwilliger, T.C.10
-
22
-
-
33751247668
-
Protein complex expression by using multigene baculoviral vectors
-
DOI 10.1038/nmeth983, PII NMETH983
-
Fitzgerald, D. J. et al. Protein complex expression by using multigene baculoviral vectors. Nature Methods 3, 1021-1032 (2006). (Pubitemid 44782702)
-
(2006)
Nature Methods
, vol.3
, Issue.12
, pp. 1021-1032
-
-
Fitzgerald, D.J.1
Berger, P.2
Schaffitzel, C.3
Yamada, K.4
Richmond, T.J.5
Berger, I.6
-
23
-
-
0031059866
-
Processing of X-ray diffraction data collected in oscillation mode
-
DOI 10.1016/S0076-6879(97)76066-X
-
Otwinowski, Z. & Minor, W. Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol. 276, 307-326 (1997). (Pubitemid 27085611)
-
(1997)
Methods in Enzymology
, vol.276
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
24
-
-
0031058188
-
Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods
-
DOI 10.1016/S0076-6879(97)76073-7
-
de La Fortelle, E. & Bricogne, G. Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods. Methods Enzymol. 276, 472-494 (1997). (Pubitemid 27085618)
-
(1997)
Methods in Enzymology
, vol.276
, pp. 472-494
-
-
De La Fortelle, E.1
Bricogne, G.2
-
25
-
-
16644377724
-
Towards complete validated models in the next generation of ARP/wARP
-
DOI 10.1107/S0907444904027556
-
Cohen, S. X. et al. Towards complete validated models in the next generation of ARP/wARP. Acta Crystallogr. D 60, 2222-2229 (2004). (Pubitemid 41742774)
-
(2004)
Acta Crystallographica Section D: Biological Crystallography
, vol.60
, Issue.12
, pp. 2222-2229
-
-
Cohen, S.X.1
Morris, R.J.2
Fernandez, F.J.3
Jelloul, M.B.4
Kakaris, M.5
Parthasarathy, V.6
Lamzin, V.S.7
Kleywegt, G.J.8
Perrakis, A.9
-
27
-
-
13244281317
-
Model-building tools for molecular graphics
-
Emsley, P. & Cowtan, K. Coot: model-building tools for molecular graphics. Acta Crystallogr. D 60, 2126-2132 (2004).
-
(2004)
Acta Crystallogr. D
, vol.60
, pp. 2126-2132
-
-
Emsley, P.1
Coot, C.K.2
-
28
-
-
0034009520
-
Size-distribution analysis of macromolecules by sedimentation velocity ultracentrifugation and Lamm equation modeling
-
Schuck, P. Size-distribution analysis ofmacromolecules by sedimentation velocity ultracentrifugation and Lamm equation modeling. Biophys. J. 78, 1606-1619 (2000). (Pubitemid 30141584)
-
(2000)
Biophysical Journal
, vol.78
, Issue.3
, pp. 1606-1619
-
-
Schuck, P.1
-
29
-
-
27744500994
-
Subunit arrangement and function in NMDA receptors
-
DOI 10.1038/nature04089, PII N04089
-
Furukawa, H., Singh, S. K., Mancusso, R. & Gouaux, E. Subunit arrangement and function in NMDA receptors. Nature 438, 185-192 (2005). (Pubitemid 41599865)
-
(2005)
Nature
, vol.438
, Issue.7065
, pp. 185-192
-
-
Furukawa, H.1
Singh, S.K.2
Mancusso, R.3
Gouaux, E.4
|