Differential activation of individual subunits in heteromeric kainate receptors

Neuron

Volumn 34, Issue 4, 2002, Pages 589-598

  Swanson, Geoffrey T ^a   Green, Tim ^b   Sakai, Ryuichi ^c   Contractor, Anis ^d   Che, Wesley ^d   Kamiya, Hisao ^c   Heinemann, Stephen F ^d  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c KITASATO UNIVERSITY   (Japan)

^d SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; DYSIHERBAINE; GLUTAMIC ACID; KAINIC ACID RECEPTOR; KAINIC ACID RECEPTOR AGONIST; KAINIC ACID RECEPTOR ANTAGONIST; PROTEIN; PROTEIN GLUR5; RECEPTOR SUBUNIT; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION;

EID: 0037118264     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(02)00676-1     Document Type: Article

References (20)

1. A molecular envelope of the ligand-binding domain of a glutamate receptor in the presence and absence of agonist
2. Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: Crystal structures of the GluR2 ligand binding core
3. Structure of a glutamate-receptor ligand-binding core in complex with kainate
4. Heteromeric kainate receptors formed by the coassembly of GluR5, GluR6, and GluR7
5. The glutamate receptor ion channels
6. Cloning of a cDNA for a glutamate receptor subunit activated by kainate but not AMPA
7. The KA-2 subunit of excitatory amino acid receptors shows widespread expression in brain and forms ion channels with distantly related subunits
8. Cloned glutamate receptors
9. Selective modulation of desensitization at AMPA versus kainate receptors by cyclothiazide and concanavalin A
10. GluR5 and GluR6 kainate receptor subunits coexist in hippocampal neurons and coassemble to form functional receptors
11. The tetrameric structure of a glutamate receptor channel
12. Pharmacological properties of the potent epileptogenic amino acid dysiherbaine, a novel glutamate receptor agonist isolated from the marine sponge dysidea herbacea
13. Rat GluR7 and a carboxy-terminal splice variant, GluR7b, are functional kainate receptor subunits with a low sensitivity to glutamate
14. Concentration-dependent substate behavior of native AMPA receptors
15. A glutamate receptor channel with high affinity for domoate and kainate
16. Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins
17. Identification of amino acid residues that control functional behavior in GluR5 and GluR6 kainate receptors
18. Kainate receptors exhibit differential sensitivities to (S)-5-iodowillardiine
19. The lurcher mutation of an alpha-amino-3-hydroxy-5-methyl- 4-isoxazolepropionic acid receptor subunit enhances potency of glutamate and converts an antagonist to an agonist
20. Cloning of a putative high-affinity kainate receptor expressed predominantly in hippocampal CA3 cells