Design, synthesis, and biological evaluation of a scaffold for iGluR ligands based on the structure of (-)-dysiherbaine

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 8, 2006, Pages 2189-2194

  Cohen, Jamie L ^a   Limon, Agenor ^a   Miledi, Ricardo ^a   Chamberlin, A Richard ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Dysiherbaine; Excitatory amino acid receptors; KA receptor agonist; KA reeptor antagonist; NMDA receptor agonist; Scaffold

Indexed keywords

AMPA RECEPTOR AGONIST; DYSIHERBAINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR STIMULATING AGENT;

ARTICLE; CYCLIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; EVALUATION; LIGAND BINDING; MOLECULAR DYNAMICS;

ALANINE; ANIMALS; BENZOFURANS; BICYCLO COMPOUNDS, HETEROCYCLIC; CEREBRAL CORTEX; EXCITATORY AMINO ACID ANTAGONISTS; LIGANDS; RATS; RECEPTORS, GLUTAMATE; RECEPTORS, N-METHYL-D-ASPARTATE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33644804186     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.01.047     Document Type: Article

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