The N-methyl-D-aspartate receptor subunit NR2B: Localization, functional properties, regulation, and clinical implications

Pharmacology and Therapeutics

Volumn 97, Issue 1, 2003, Pages 55-85

  Loftis, Jennifer M ^a,b   Janowsky, Aaron ^a,b,c  

^a PORTLAND VA MEDICAL CENTER   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Cytoskeleton; Excitotoxicity; Glutamate; Kinase; Postsynaptic density; Synaptic plasticity

Indexed keywords

2 AMINO 4 PHOSPHONOMETHYL 3 HEPTENOIC ACID; 4 BENZYL ALPHA (4 HYDROXYPHENYL) BETA METHYL 1 PIPERIDINEPROPANOL; 4 PHOSPHONOMETHYLPIPECOLIC ACID; AMIDE; CGP 61594; CON G; CON R; CP 283 097; CYTOSKELETON PROTEIN; DIZOCILPINE; ELIPRODIL; FELBAMATE; GLYCINE DERIVATIVE; GLYCINE RECEPTOR ANTAGONIST; HOMOQUINOLINATE; IFENPRODIL; LEVODOPA; MEMANTINE; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; QUINOLINIC ACID DERIVATIVE; RECEPTOR SUBUNIT; RO G3 1908; STAUROSPORINE; TRAXOPRODIL; UNCLASSIFIED DRUG; UNINDEXED DRUG; NR2B NMDA RECEPTOR;

ALCOHOL ABUSE; ALCOHOL WITHDRAWAL; ALZHEIMER DISEASE; ANALGESIC ACTIVITY; ANTINOCICEPTION; ARTICLE; BINDING AFFINITY; BRAIN HYPOXIA; BRAIN ISCHEMIA; BRAIN REGION; CELLULAR DISTRIBUTION; CLINICAL TRIAL; DIABETES MELLITUS; DOSE RESPONSE; DRUG ABUSE; DRUG BINDING SITE; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; DRUG SELECTIVITY; ELECTROPHYSIOLOGY; ENZYME INHIBITION; FEEDING BEHAVIOR; HUMAN; HUNTINGTON CHOREA; IMMUNOREACTIVITY; LEARNING; MEMORY; NEGATIVE SYNDROME; NERVE CELL PLASTICITY; NEUROTRANSMISSION; NOCICEPTION; NONHUMAN; PARKINSON DISEASE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REGULATORY MECHANISM; SCHIZOPHRENIA; SEIZURE; SIGNAL TRANSDUCTION; STOICHIOMETRY; SYNAPTIC TRANSMISSION; TREATMENT OUTCOME; ADDICTION; ANIMAL; ANTIBODY SPECIFICITY; BIOSYNTHESIS; EPILEPSY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PAIN; PHYSIOLOGY; REVIEW;

ALZHEIMER DISEASE; ANIMALS; DIABETES MELLITUS; EPILEPSY; GENE EXPRESSION REGULATION; HUMANS; HUNTINGTON DISEASE; HYPOXIA-ISCHEMIA, BRAIN; ORGAN SPECIFICITY; PAIN; PARKINSON DISEASE; RECEPTORS, N-METHYL-D-ASPARTATE; SCHIZOPHRENIA; SUBSTANCE-RELATED DISORDERS; SYNAPTIC TRANSMISSION;

EID: 0037216407     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0163-7258(02)00302-9     Document Type: Review

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