Mechanisms of activation, inhibition and specificity: Crystal structures of the NMDA receptor NR1 ligand-binding core

EMBO Journal

Volumn 22, Issue 12, 2003, Pages 2873-2885

  Furukawa, Hiroyasu ^a   Gouaux, Eric ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Ligand gated ion channel; NMDA receptor; S1S2 ligand binding core

Indexed keywords

5,7 DICHLOROKYNURENIC ACID; CYCLOSERINE; DEXTRO SERINE; GLUTAMATE RECEPTOR; GLUTAMIC ACID; GLYCINE; IONOTROPIC RECEPTOR; LIGAND; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

AGONIST; ALLOSTERISM; ARTICLE; BINDING AFFINITY; CENTRAL NERVOUS SYSTEM; CRYSTAL STRUCTURE; LIGAND BINDING; NERVE CELL DIFFERENTIATION; NEUROTRANSMISSION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN INTERACTION; RECEPTOR BINDING; RECEPTOR DOWN REGULATION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DISULFIDES; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; GLYCINE; KYNURENIC ACID; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN SUBUNITS; RATS; RECEPTORS, AMPA; RECEPTORS, N-METHYL-D-ASPARTATE; SEQUENCE ALIGNMENT; SERINE;

MAMMALIA;

EID: 0038037859     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg303     Document Type: Article

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