Serines 890 and 896 of the NMDA receptor subunit NR1 are differentially phosphorylated by protein kinase C isoforms

Neurochemistry International

Volumn 47, Issue 1-2 SPEC. ISS., 2005, Pages 84-91

  Sánchez Pérez, Ana M ^a   Felipo, Vicente ^a  

^a Laboratorio de Neurobiologia de Prince Felipe Research Centre   (Spain)

Author keywords

Cell surface expression; mGluR I; NMDA receptor phosphorylation; PKC isoforms

Indexed keywords

3,5 DIHYDROXYPHENYLGLYCINE; METABOTROPIC RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; PROTEIN KINASE C GAMMA; SERINE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CEREBELLUM; CONTROLLED STUDY; INTRACELLULAR SPACE; NERVE CELL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RAT;

AMINO ACID SEQUENCE; ANIMALS; ANIMALS, NEWBORN; BINDING SITES; BRAIN; CELLS, CULTURED; ENZYME INHIBITORS; EXCITATORY AMINO ACID AGONISTS; NEURONS; PHOSPHORYLATION; PROTEIN ISOFORMS; PROTEIN KINASE C; PROTEIN KINASE C-ALPHA; PROTEIN TRANSPORT; RATS; RATS, WISTAR; RECEPTOR AGGREGATION; RECEPTORS, METABOTROPIC GLUTAMATE; RECEPTORS, N-METHYL-D-ASPARTATE; SERINE; SYNAPTIC TRANSMISSION;

EID: 20544432404     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2005.04.011     Document Type: Article

References (40)

1. F. Angenstein, G. Riedel, K.G. Reyman, and S. Staak Transient translocation of protein kinase Cgamma in hippocampal long-term potentiation depends on activation of metabotropic glutamate receptors Neuroscience 93 1999 1289 1295
2. M.F. Barry, and E.B. Ziff Receptor trafficking and the plasticity of excitatory synapses Curr. Opin. Neurobiol. 12 2002 279 286
3. F. Battaini Protein kinase C isoforms as therapeutic targets in nervous system disease states Pharmacol. Res. 44 2001 353 361
4. D.W. Choi Glutamate neurotoxicity and diseases of the nervous system Neuron 1 1988 623 634
5. G.L. Collingridge, and T.V. Bliss Memories of NMDA receptors and LTP Trends Neurosci. 18 1995 54 56
6. P.J. Colombo, W.C. Wetsel, and M. Gallagher Spatial memory is related to hippocampal subcellular concentrations of calcium-dependent protein kinase C isoforms in young and aged rats Proc. Natl. Acad. Sci. U.S.A. 94 1997 14195 14199
7. B.R.K. Douma, E.A. Vanderzee, and P.G.M. Luiten Translocation of protein kinase C gamma occurs during the early phase of acquisition of food rewarded spatial learning Behav. Neurosci. 112 1998 496 501
8. V. Felipo, M.D. Miñana, I. Azorín, and S. Grisolía Induction of rat brain tubulin following ammonium ingestion J. Neurochem. 51 1988 1041 1045
9. V. Felipo, and R.F. Butterworth Neurobiology of Ammonia Progr. Neurobiol. 67 2002 259 279
10. G. Giordano, A.M. Sánchez-Pérez, M. Burgal, C. Montoliu, L. Costa, and V. Felipo Chronic exposure to ammonia induces isoform-selective alterations in the intracellular distribution and NMDA receptor-mediated translocation of protein kinase C in cerebellar neurons in culture J. Neurochem. 92 2005 143 157
11. J. Goossens, H. Daniel, A. Rancillac, J. Vander Steen, J. Oberdick, F. Crepel, C.I. DeZeeuw, and M.A. Frens Expression of protein kinase C inhibitor blocks cerebellar long-term depression without affecting Purkinje cell excitability in alert mice J. Neurosci. 21 2001 5813 5823
12. B. Gorg, N. Foster, R. Reinehr, H.J. Bidmon, A. Hongen, D. Haussinger, and F. Schliess Benzodiazepine-induced protein tyrosine nitration in rat astrocytes Hepatology 37 2003 245 248
13. C. Hermenegildo, C. Montoliu, M. Llansola, M.D. Muñoz, J.M. Gaztelu, M.D. Miñana, and V. Felipo Chronic hyperammonemia impairs glutamate-nitric oxide-cyclic GMP pathway in cerebellar neurons in culture and in the rat in vivo Eur. J. Neurosci. 10 1998 3201 3209
14. C. Keenan, N. Goode, and C. Pears Isoform specificity of activators and inhibitors of protein kinase C gamma and delta FEBS Lett. 22 1997 101 108
15. Y. Liu, and J. Zhang Recent development in NMDA receptors Chin. Med. J. 113 2000 948 956
16. J.F. MacDonald, S.A. Kotecha, W.Y. Lu, and M.F. Jackson Convergence of PKC-dependent kinase signal cascades on NMDA receptors Curr. Drug Targets 2 2001 299 312
17. R.C. Malenka, and R.A. Nicoll Long-term potentiation - a decade of progress? Science 1999 1870 1874
18. G. Marcaida, M.D. Miñana, M. Burgal, S. Grisolía, and V. Felipo Ammonia prevents activation of NMDA receptors in rat cerebellar neuonal cultures Eur. J. Neurosci. 7 1995 2389 2396
19. G. Martiny-Baron, M.G. Kazanietz, H. Mischak, P.M. Blumberg, G. Kochs, H. Hug, D. Marme, and C. Schachtele Selective inhibition of protein kinase C isozymes by the indolocarbazole Go 6976 J. Biol. Chem. 268 1993 9194 9197
20. A. Michalak, K. Knecht, and R.F. Butterworth Hepatic encephalopathy in acute liver failure: role of the glutamate system Adv. Exp. Med. Biol. 420 1997 35 44
21. M.D. Miñana, C. Llansola, C. Hermenegildo, C. Cucarella, C. Montoliu, S. Grisolía, and V. Felipo Glutamate and muscarinic receptors in the molecular mechanisms of acute ammonia toxicity and of its prevention Adv. Exp. Med. Biol. 420 1997 45 56
22. M.D. Miñana, C. Montoliu, M. Llansola, S. Grisolía, and V. Felipo Nicotine prevents glutamate-induced proteolysis of the microtubule-associated protein MAP-2 and glutamate neurotoxicity in primary cultures of cerebellar neurons Neuropharmacology 37 1998 847 857
23. P. Monfort, M.D. Muñoz, A. ElAyadi, E. Kosenko, and V. Felipo Effects of hyperammonemia and liver failure on glutamatergic neurotransmission Metab. Brain Dis. 17 4 2002 237 250
24. H. Mori, and M. Mishina Structure and function of the NMDA receptor channel Neuropharmacology 34 1995 1219 1237
25. F. Moroni, G. Lombardi, G. Moneti, and C. Cortesini The release and neosynthesis of glutamic acid are increased in experimental models of hepatic encephalopathy J. Neurochem. 40 1983 850 854
26. J.P. Pin, and F. Acher The metaotropic glutamate receptors: structure, activation mechanism and pharmacology Curr. Drug Targets CNS Neurol. Disord. 1 2002 297 317
27. G.M. Ramakers, D.D. Gerendasy, and P.N. De Graan Substrate phosphorylation in the protein kinase Cgamma knockout mouse J. Biol. Chem. 274 1999 1873 1874
28. V.L.R. Rao, and C.R.K. Murthy Hyperammonemic alterations in the uptake and release of glutamate and aspartate by rat cerebellar preparations Neurosci. Lett. 130 1991 49 52
29. V.L. Rao, A.K. Agrawal, and C.R. Murhty Ammonia-induced alterations in glutamate and muscimol binding to cerebellar synaptic membranes Neurosci. Lett. 130 1991 251 254
30. V.L. Rao, and C.R. Murthy Hyperammonemic alterations in the metabolism of glutamate and aspartate in rat cerebellar astrocytes Neurosci. Lett. 138 1992 107 110
31. K.W. Roche, W.G. Tingley, and R.L. Huganir Glutamate receptor phosphorylation and synaptic plasticity Curr. Opin. Neurobiol. 4 1994 383 388
32. S.M. Saleh, L.J. Takemoto, D. Zoukhri, and D.J. Takemoto PKC g phosphorylation of connexin 46 in the lens cortex Mol. Vision 7 2001 240 246
33. D. Sott, T. Blanpied, G. Swanson, C. Zhang, and M.D. Ehlers An NMDA receptor ER signal regulated by phosphorylation and alternative splicing J. Neurosci. 21 2003 3063 3072
34. P.C. Suen, K. Wu, J.L. Xu, S.Y. Lin, E.S. Levine, and I.B. Black NMDA receptor subunits in the postsynaptic density of rat brain: expression and phosphorylation by endogenous protein kinases. Brain Res. Mol. Brain Res. 59 1998 215 228
35. S.L. Swope, S.J. Moss, L.A. Raymond, and R.L. Huganir Regulation of ligand-gated ion channels by protein phosphorylation Adv. Second Messenger Phosphoprotein Res. 33 1999 49 78
36. W.G. Tingley, M.D. Ehlers, K. Kameyama, C. Doherty, J.B. Ptak, C.T. Riley, and R.L. Huganir Characterization of protein kinase A and protein kinase C phosphorylation of the N-methyl-d-aspartate receptor NR1 subunit using phosphorylation site-specific antibodies J. Biol. Chem. 272 1997 5157 5166
37. W.G. Tingley, K.W. Roche, A.K. Thompson, and R.L. Huganir Regulation of NMDA receptor phosphorylation by alternative splicing of the C-terminal domain Nature 364 1993 70 73
38. J.C. Todt, B. Hu, A. Punturieri, J. Sonstein, T. Polak, and J.L. Curtis Activation of protein kinase C βII by the stereo- specific phosphatydylserine receptor is required for phagocytosis of apoptotic thymocytes by resident murine tissue macrophages J. Biol. Chem. 277 2002 35906 35914
39. H. Urushihara, M. Tohda, and Y. Nomura Selective potentiation of N-methyl-d-aspartate-induced current by protein kinase C in Xenopus oocytes injected with rat brain RNA J. Biol. Chem. 267 1992 11697 11700
40. Z.H. Zhang, J.A. Johnson, L. Chen, N. El-Sherif, D. Mochly-Rosen, and M. Boutjdir C2 region-derived peptides of beta-protein kinase C regulate cardiac Ca2+ channels Circ. Res. 80 1997 720 729