Stereocontrolled synthesis and pharmacological evaluation of azetidine-2,3-dicarboxylic acids at NMDA receptors

ChemMedChem

Volumn 4, Issue 1, 2009, Pages 110-117

  Sivaprakasam, Mangaleswaran ^b   Hansen, Kasper B ^a,c   David, Olivier ^b   Nielsen, Birgitte ^a   Traynelis, Stephen F ^c   Clausen, Rasmus P ^a   Couty, François ^b   Bunch, Lennart ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Conformational restriction; Enantioselectivity; Glutamate; NMDA; Receptors

Indexed keywords

AMINO ACID; AZETIDINE 2,3 DICARBOXYLIC ACID DERIVATIVE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2C; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2D; N METHYL DEXTRO ASPARTIC ACID RECEPTOR STIMULATING AGENT; RADIOLIGAND; UNCLASSIFIED DRUG;

ARTICLE; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTROPHYSIOLOGY; ENANTIOMER; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEREOISOMERISM;

EID: 58549090123     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.200800226     Document Type: Article

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