Comparative analysis of different competitive antagonists interaction with NR2A and NR2B subunits of N-methyl-D-aspartate (NMDA) ionotropic glutamate receptor

Journal of Molecular Modeling

Volumn 11, Issue 6, 2005, Pages 489-502

  Blaise, Mathias Costa ^a   Sowdhamini, Ramanathan ^b   Pradhan, Nithyananda ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES   (India)

^b TATA INSTITUTE OF FUNDAMENTAL RESEARCH   (India)

Author keywords

Binding pocket; Competitive antagonist; Docking; Homology modeling; NMDA receptor; NR2A; NR2B

Indexed keywords

2 AMINO 4 METHYL 5 PHOSPHONO 3 PENTENOIC ACID; 2 AMINO 4 METHYL 5 PHOSPHONO 3 PENTENOIC ACID ETHYL ESTER; 2 AMINO 5 PHOSPHONOVALERIC ACID; 2 AMINO 7 PHOSPHONOHEPTANOIC ACID; 4 (3 PHOSPHONOPROPYL) 2 PIPERAZINECARBOXYLIC ACID; 5,7 DICHLOROKYNURENIC ACID; CARBON; GLUTAMATE RECEPTOR; HYDROGEN; LIGAND; LYSINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; RECEPTOR SUBUNIT;

ARTICLE; BINDING COMPETITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG RECEPTOR BINDING; DRUG STRUCTURE; EXPERIMENTATION; HYDROGEN BOND; HYDROPHILICITY; LIGAND BINDING; MOLECULAR MECHANICS; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN CONFORMATION; RECEPTOR AFFINITY;

AMINO ACID SEQUENCE; BINDING SITES; CONSERVED SEQUENCE; HYDROGEN BONDING; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; RECEPTORS, N-METHYL-D-ASPARTATE; SEQUENCE ALIGNMENT;

EID: 29244446841     PISSN: 16102940     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00894-005-0258-5     Document Type: Article

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