Structural features of the glutamate binding site in recombinant NR1/NR2A N-methyl-D-aspartate receptors determined by site-directed mutagenesis and molecular modeling

Molecular Pharmacology

Volumn 67, Issue 5, 2005, Pages 1470-1484

  Chen, Philip E ^a   Geballe, Matthew T ^b   Stansfeld, Phillip J ^a   Johnston, Alexander R ^a   Yuan, Hongjie ^c   Jacob, Amanda L ^c   Snyder, James P ^b   Traynelis, Stephen F ^c   Wyllie, David J A ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b EMORY UNIVERSITY   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPA RECEPTOR AGONIST; ASPARTIC ACID; GLUTAMIC ACID; GLYCINE; METHANETHIOSULFONATE ETHYLAMMONIUM; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; SULFONIC ACID DERIVATIVE; TETRAZOL 5 YL GLYCINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CONTROLLED STUDY; LIGAND BINDING; MOLECULAR DYNAMICS; MOLECULAR MODEL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; SITE DIRECTED MUTAGENESIS; VOLTAGE CLAMP; XENOPUS LAEVIS;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID AGONISTS; FEMALE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; RECEPTORS, N-METHYL-D-ASPARTATE; RECOMBINANT PROTEINS; XENOPUS LAEVIS;

EID: 17844387335     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.104.008185     Document Type: Article

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