Characterization and comparison of the NR3A subunit of the NMDA receptor in recombinant systems and primary cortical neurons

Journal of Neurophysiology

Volumn 87, Issue 4, 2002, Pages 2052-2063

  Sasaki, Yasnory F ^a,b,c   Rothe, Thomas ^c,d   Premkumar, Louis S ^e   Das, Saumya ^b,c   Cui, Jiankun ^a   Talantova, Maria V ^a   Wong, Hon Kit ^f   Gong, Xiandi ^f   Chan, Shing Fai ^f   Zhang, Dongxian ^a,c,d   Nakanishi, Nobuki ^a,b,c   Sucher, Nikolaus J ^f   Lipton, Stuart A ^a,c,d  

^a BURNHAM INSTITUTE   (United States)

^b Department of Neurobiology ^*  (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; RECEPTOR SUBTYPE; RECOMBINANT RECEPTOR;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; BRAIN CELL; CALCIUM TRANSPORT; CELL STRAIN COS1; CHANNEL GATING; CONTROLLED STUDY; DNA LIBRARY; ELECTROPHYSIOLOGY; IMMUNOBLOTTING; IN SITU HYBRIDIZATION; NONHUMAN; OOCYTE; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0036095463     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.00531.2001     Document Type: Article

References (35)

1. Binding sites for permeant ions in the channel of NMDA receptors and their effects on channel block
2. Cell culture of neocortex and basal forebrain from postnatal rats
3. Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and α1-syntrophin mediated by PDZ domains
4. X-1: A developmentally regulated member of a novel class of the ionotropic glutamate receptor family
5. Oxidative damage to the c-fos gene and reduction of its transcription after focal cerebral ischemia
6. Increased NMDA current and spine density in mice lacking the NMDAR subunit, NR3A
7. Splice variant specific interaction of the NMDA receptor subunit NR1 with neuronal intermediate filaments
8. Inactivation of NMDA receptors by direct interaction of calmodulin with the NR1 subunit
9. Isolation of neurons suitable for patch-clamping from adult mammalian central nervous systems
10. Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95
11. AMPA receptor subunits expressed by single Purkinje cells
12. Stimulus-induced coordinate changes in mRNA abundance in single postsynaptic hippocampal CAl neurons
13. Permeation and block of N-methyl-D-aspartic acid receptor channels by divalent cations in mouse cultured central neurones
14. 2+ of NMDA responses in spinal cord neurones
15. N-methyl-D-aspartic acid receptor structure and function
16. Physiological and pathophysiological roles of excitatory amino acids during central nervous system development
17. Polymerase chain reaction of ion channel expression in single neurons of brain slices
18. Correction for liquid junction potentials in patch-clamp experiments
19. Interaction between the C terminus of NMDA receptor subunits and multiple members of the PSD-95 family of membrane-associated guanylate kinases
20. Magnesium gates glutamate-activated channels in mouse central neurones
21. Assembly with the NR1 subunit is required for surface expression of NR3A-containing NMDA receptors
22. Stoichiometry of recombinant N-methyl-D-aspartate receptor channels inferred from single-channel current patterns
23. Subconductance states of a mutant NMDA receptor channel. Kinetics, calcium, and voltage-dependence
24. The characterization and localization of the glutamate receptor subunit G1ur1 in the rat brain
25. 2+ influx and reversal potentials in recombinant N-methyl-D-aspartate receptor channels
26. Changing subunit composition of heteromeric NMDA receptors during development of rat cortex
27. Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo
28. Single-channel conductances of NMDA receptors expressed from cloned cDNAs: Comparison with native receptors
29. Single channel properties of cloned NMDA receptors in a human cell line: Comparison with results from Xenopus oocytes
30. Blockade of NMDA-activated channels by magnesium in the immature rat hippocampus
31. Developmental and regional expression pattern of a novel NMDA receptor-like subunit (NMDAR-L) in the rodent brain
32. PCR and patch-clamp analysis in single neurons
33. Identification of a long variant of mRNA encoding the NR3 subunit of the NMDA receptor: Its regional distribution and developmental expression in the rat brain
34. Single-channel activations and concentration jumps: Comparison of recombinant NR1a/NR2A and NR1a/NR2D NMDA receptors
35. Competitive binding of alpha-actinin and calmodulin to the NMDA receptor