Proteases involved in cartilage matrix degradation in osteoarthritis

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1824, Issue 1, 2012, Pages 133-145

  Troeberg, Linda ^a   Nagase, Hideaki ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Aggrecanase; Cartilage; Collagenase; Osteoarthritis; Proteinase

Indexed keywords

ADAM PROTEIN; ADAMTS1 PROTEIN; AGGRECAN; AGGRECANASE 2; CALPAIN; CATHEPSIN; COLLAGEN; COLLAGEN TYPE 2; COLLAGENASE; COLLAGENASE 3; CYSTEINE PROTEINASE; DISCOIDIN DOMAIN RECEPTOR; FIBROBLAST GROWTH FACTOR 2; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; MATRIX METALLOPROTEINASE; MESSENGER RNA; MICRORNA; PROTEINASE; PROTEINASE ACTIVATED RECEPTOR 2; SERINE PROTEINASE; SIRTUIN 1; SULFATASE; SYNDECAN 4; TISSUE INHIBITOR OF METALLOPROTEINASE; TRANSCRIPTION FACTOR RUNX2; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG; WNT PROTEIN;

CARTILAGE; CARTILAGE CELL; CELL DIFFERENTIATION; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PURIFICATION; GENE EXPRESSION REGULATION; HUMAN; IMMUNE SYSTEM; INFLAMMATION; KNEE OSTEOARTHRITIS; NONHUMAN; OSTEOARTHRITIS; OSTEOBLAST; OSTEOCLAST; PRIORITY JOURNAL; PROTEIN DEGRADATION; REVIEW; RNA SEQUENCE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TRANSGENIC MOUSE;

ADAM PROTEINS; ANIMALS; CARTILAGE; COLLAGENASES; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MATRIX METALLOPROTEINASES; MICE; MODELS, BIOLOGICAL; OSTEOARTHRITIS; PEPTIDE HYDROLASES; PROTEOLYSIS;

MUS MUSCULUS;

EID: 82755197933     PISSN: 15709639     EISSN: 18781454     Source Type: Journal    
DOI: 10.1016/j.bbapap.2011.06.020     Document Type: Review

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