Purification and cloning of aggrecanase-1: A member of the ADAMTS family of proteins

Science

Volumn 284, Issue 5420, 1999, Pages 1664-1666

  Tortorella, M D ^a   Burn, T C ^a   Pratta, M A ^a   Abbaszade, I ^a   Hollis, J M ^a   Liu, R ^a   Rosenfeld, S A ^a   Copeland, R A ^a   Decicco, C P ^a   Wynn, R ^a   Rockwell, A ^a   Yang, F ^a   Duke, J L ^a   Solomon, K ^a   George, H ^a   Bruckner, R ^a   Nagase, H ^b   Itoh, Y ^b,c   Ellis, D M ^a   Ross, H ^a   Wiswall, B H ^a   Murphy, K ^a   Hillman Jr , M C ^a   Hollis, G F ^a   Newton, R C ^a   Magolda, R L ^a   Trzaskos, J M ^a   Arner, E C ^a   more..

^a DUPONT COMPANY   (United States)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AGGRECAN; AGGRECANASE 1; DISINTEGRIN; METALLOPROTEINASE; PROTEINASE; THROMBOSPONDIN; UNCLASSIFIED DRUG;

ARTHRITIS; ARTICLE; ARTICULAR CARTILAGE; CLONING; DROSOPHILA; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME PURIFICATION; GENETIC TRANSFECTION; HUMAN; IMMUNOBLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN TARGETING; SEQUENCE ANALYSIS;

ADAM PROTEINS; AGGRECANS; AMINO ACID SEQUENCE; ARTHRITIS; CARTILAGE; CATALYTIC DOMAIN; CLONING, MOLECULAR; DISINTEGRINS; EXTRACELLULAR MATRIX PROTEINS; HUMANS; HYDROXAMIC ACIDS; INTERLEUKIN-1; LECTINS, C-TYPE; METALLOENDOPEPTIDASES; MOLECULAR SEQUENCE DATA; PROCOLLAGEN N-ENDOPEPTIDASE; PROTEASE INHIBITORS; PROTEIN SORTING SIGNALS; PROTEOGLYCANS; RECOMBINANT PROTEINS; SEQUENCE ANALYSIS;

EID: 0345211445     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.284.5420.1664     Document Type: Article

References (34)

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