Syndecan-1 expression is upregulated in degenerating articular cartilage in a transgenic mouse model for osteoarthritis

Scandinavian Journal of Rheumatology

Volumn 34, Issue 6, 2005, Pages 469-474

  Salminen Mankonen, H ^a   Saamanen A M ^a   Jalkanen, M ^b   Vuorio, E ^a   Pirila L ^a  

^a UNIVERSITY OF TURKU   (Finland)

^b Faron Pharmaceuticals Oy   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PROTEOHEPARAN SULFATE; SYNDECAN 1;

AGED; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CARTILAGE DEGENERATION; CONTROLLED STUDY; DISEASE COURSE; EXPERIMENTAL MOUSE; GENE EXPRESSION; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; KNEE OSTEOARTHRITIS; MOUSE; NEWBORN; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RNA EXTRACTION; RNA SYNTHESIS; TRANSGENIC MOUSE; UPREGULATION;

ANIMALS; BLOTTING, NORTHERN; CARTILAGE, ARTICULAR; IMMUNOHISTOCHEMISTRY; KNEE JOINT; MEMBRANE GLYCOPROTEINS; MICE; MICE, TRANSGENIC; OSTEOARTHRITIS, KNEE; PROTEOGLYCANS; RNA, MESSENGER; SYNDECAN-1; SYNDECANS; UP-REGULATION;

EID: 30344436341     PISSN: 03009742     EISSN: 15027732     Source Type: Journal    
DOI: 10.1080/03009740500304338     Document Type: Article

References (22)

1. Steinfeld R, Van Den Berghe H, David G. Stimulation of fibroblast growth factor receptor-1 occupancy and signaling by cell surface-associated syndecans and glypican. J Cell Biol 1996;133:405-16.
2. Bernfield M, Kokenyesi R, Kato M, Hinkes MT, Spring J, Gallo RL, et al. Biology of the syndecans: a family of transmembrane heparan sulfate proteoglycans. Annu Rev Cell Biol 1992;8:365-93.
3. Elenius K, Salmivirta M, Inki P, Mali M, Jalkanen M. Binding of human syndecan to extracellular matrix proteins. J Biol Chem 1990;15:17837-43.
4. David G, Bernfield M. The emerging roles of cell surface heparan sulfate proteoglycans. Matrix Biol 1998;17:461-3.
5. Trautman MS, Kimelman J, Bernfield M. Developmental expression of syndecan, an integral membrane proteoglycan, correlates with cell differentiation. Development 1991;111:213-20.
6. Solursh M, Reiter RS, Jensen KL, Kato M, Bernfield M. Transient expression of a cell surface heparan sulfate proteoglycan (syndecan) during limb development. Dev Biol 1990;140:83-92.
7. Vainio S, Jalkanen M, Vaahtokari A, Sahlberg C, Mali M, Bernfield M, et al. Expression of syndecan gene is induced early, is transient, and correlates with changes in mesenchymal cell proliferation during tooth organogenesis. Dev Biol 1991;147:322-33.
8. Kainulainen V, Wang H, Schick C, Bernfield M. Syndecans, heparan sulfate proteoglycans, maintain the proteolytic balance of acute wound fluids. J Biol Chem 1998;8:11563-9.
9. Gao G, Plaas A, Thopson VP, Jin S, Zuo F, Sandy JD. ADAMTS4 activation on the cell surface involves C-terminal cleavage by glycosylphosphatidyl inositol-anchored membrane type 4-matrix metalloproteinase and binding of the activated proteinase to chondroitin sulfate and heparan sulfate on syndecan-1. J Biol Chem 2004;12:10042-51.
10. Dhodapkar MV, Abe E, Theus A, Lacy M, Langford JK, Barlogie B, et al. Syndecan-1 is a multifunctional regulator of myeloma pathobiology: control of tumor cell survival, growth and bone cell differentiation. Blood 1998;91:2679-88.
11. Barre PE, Redini F, Boumediene K, Vielpeau C, Pujol JP. Semiquantitative reverse transcription-polymerase chain reaction analysis of syndecan-1 and -4 messages in cartilage and cultured chondrocytes from osteoarthritic joints. Osteoarthritis Cartilage 2000;8:34-43.
12. Saamanen AK, Salminen HJ, Dean PB, De Crombrugghe B, Vuorio EI, Metsaranta MP. Osteoarthritis-like lesions in transgenic mice harboring a small deletion mutation in type II collagen gene. Osteoarthritis Cartilage 2000;8:248-57.
13. Salminen H, Vuorio E, Saamanen AM. Expression of Sox9 and type IIA procollagen during attempted repair of articular cartilage damage in a transgenic mouse model of osteoarthritis. Arthritis Rheum 2001;44:947-55.
14. Elenius K, Vainio S, Laato M, Salmivirta M, Thesleff I, Jalkanen M. Induced expression of syndecan in healing wounds. J Cell Biol 1991;114:585-95.
15. Metsaranta M, Garofalo S, Decker G, Rintala M, De CB, Vuorio E. Chondrodysplasia in transgenic mice harboring a 15-amino acid deletion in the triple helical domain of proalpha-1-II collagen chain. J Cell Biol 1992;118:203-12.
16. Chirgwin JM, Przybyla AE, MacDonald RJ, Rutter WJ. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 1979;27:5294-9.
17. Saunders S, Jalkanen M, O'Farrell S, Bernfield M. Molecular cloning of syndecan, an integral membrane proteoglycan. J Cell Biol 1989;108:1547-56.
18. Jalkanen M, Nguyen H, Rapraeger A, Kurn N, Bernfield M. Heparan sulfate proteoglycans from mouse mammary epithelial cells: localization on the cell surface with a monoclonal antibody. J Cell Biol 1985;101:976-84.
19. Sandell LJ, Aigner T. Articular cartilage and changes in arthritis. An introduction: cell biology of osteoarthritis. Arthritis Res 2001;3:107-13.
20. Burbach BJ, Friedl A, Mundhenke C, Rapraeger AC. Syndecan-1 accumulates in lysosomes of poorly differentiated breast carcinoma cells. Matrix Biol 2003;22:163-77.
21. Salminen HJ, Saamanen AM, Vankemmelbeke MN, Auho PK, Perala MP, Vuorio EI. Differential expression patterns of matrix metalloproteinases and their inhibitors during development of osteoarthritis in a transgenic mouse model. Ann Rheum Dis 2002;61:591-7.
22. Molteni A, Modrowski D, Hott M, Marie PJ. Differential expression of fibroblast growth factor receptor-1, -2, and -3 and syndecan-1, -2, and -4 in neonatal rat mandibular condyle and calvaria during osteogenic differentiation in vitro. Bone 1999;24:337-47.