Inhibition of furin-like enzymes blocks interleukin-1α/oncostatin M-stimulated cartilage degradation

Arthritis and Rheumatism

Volumn 48, Issue 4, 2003, Pages 1057-1066

  Milner, J M ^a   Rowan, A D ^a   Elliott, S F ^a   Cawston, T E ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; COLLAGENASE; ENZYME INHIBITOR; FURIN; GELATINASE; GELATINASE A; GLYCOSAMINOGLYCAN POLYSULFATE; HYDROXYPROLINE; INTERLEUKIN 1ALPHA; INTERSTITIAL COLLAGENASE; ONCOSTATIN M; PROCOLLAGENASE; PROTEOGLYCAN; TRITIUM;

ACETYLATION; ANIMAL TISSUE; ARTHRITIS; ARTICLE; CARTILAGE DEGENERATION; CATTLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; NONHUMAN; NOSE CARTILAGE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN TARGETING; ZYMOGRAPHY;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; CATTLE; COLLAGEN; COLLAGENASES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; ENZYME INHIBITORS; FURIN; HYDROXYPROLINE; INTERLEUKIN-1; L-LACTATE DEHYDROGENASE; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 13; NASAL SEPTUM; OLIGOPEPTIDES; ONCOSTATIN M; ORGAN CULTURE TECHNIQUES; PEPTIDES; PROTEOGLYCANS; RECOMBINANT PROTEINS; SUBTILISINS;

EID: 0037386630     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.10873     Document Type: Article

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