Inhibition of histone deacetylases antagonized FGF2 and IL-1β effects on MMP expression in human articular chondrocytes

Growth Factors

Volumn 27, Issue 1, 2009, Pages 40-49

  Wang, Xibin ^a   Song, Yingjie ^a   Jacobi, Jennifer L ^a   Tuan, Rocky S ^a  

^a NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

Author keywords

Articular chondrocyte; Fibroblast growth factor; Histone deacetylase; Interleukin 1 ; Matrix metalloproteinase; Trichostatin A

Indexed keywords

AGGRECAN; COLLAGEN TYPE 2; COLLAGENASE 3; FIBROBLAST GROWTH FACTOR 2; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; INTERLEUKIN 1BETA; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE; MESSENGER RNA; STROMELYSIN; TRICHOSTATIN A;

ARTICLE; CARTILAGE CELL; CARTILAGE DEGENERATION; CONTROLLED STUDY; ENZYME INHIBITION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

AGGRECANS; CARTILAGE, ARTICULAR; CELLS, CULTURED; CHONDROCYTES; COLLAGEN TYPE II; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION REGULATION; HISTONE DEACETYLASES; HUMANS; HYDROXAMIC ACIDS; INTERLEUKIN-1BETA; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 13; MATRIX METALLOPROTEINASE 3; MATRIX METALLOPROTEINASES; SIGNAL TRANSDUCTION;

EID: 58149123407     PISSN: 08977194     EISSN: 10292292     Source Type: Journal    
DOI: 10.1080/08977190802625179     Document Type: Article

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