Knee cartilage of spinal cord-injured patients displays progressive thinning in the absence of normal joint loading and movement

Arthritis and Rheumatism

Volumn 46, Issue 8, 2002, Pages 2073-2078

  Vanwanseele, ^a,d,e   Eckstein, F ^b   Knecht, H ^c   Stussi E ^a   Spaepen, A ^d  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY OF MUNICH   (Germany)

^c SWISS PARAPLEGIC RESEARCH   (Switzerland)

^d UNIVERSITY OF LEUVEN   (Belgium)

^e Laboratory for Biomechanics   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTHROPATHY; ARTICLE; BIOMECHANICS; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; IMMOBILIZATION; IN VIVO STUDY; JOINT MOBILITY; KNEE; MALE; MORPHOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; PATELLA; PRIORITY JOURNAL; SPINAL CORD INJURY; THICKNESS; TIBIA;

EID: 0036676170     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.10462     Document Type: Article

References (35)

1. Development and reversal of a proteoglycan aggregation defect in normal canine knee cartilage after immobilization
2. Joint motion in the absence of normal loading does not maintain normal articular cartilage
3. Softening of canine articular cartilage after immobilization of the knee joint
4. Biochemical changes in articular cartilage after joint immobilization by casting or external fixation
5. Centrifugal and biochemical comparison of proteoglycan aggregates from articular cartilage in experimental joint disuse and joint instability
6. Cartilage metalloproteases in disuse atrophy
7. Coordinated regulation of hyaluronan and aggrecan content in the articular cartilage of immobilized and exercised dogs
8. Unweighting accelerates tidemark advancement in articular cartilage at the knee joint of rats
9. Mechanical behavior and biochemical composition of canine knee cartilage following periods of joint disuse and disuse with remobilization
10. Remobilization does not fully restore immobilization induced articular cartilage atrophy
11. Incomplete restoration of immobilization induced softening of young beagle knee articular cartilage after 50-week remobilization
12. Decline after immobilisation and recovery after remobilisation of synovial fluid IL1, TIMP, and chondroitin sulphate levels in young beagle dogs
13. Altered mechanics and histomorphometry of canine tibial cartilage following joint immobilization
14. Mortality, morbidity, and psychosocial outcomes of persons spinal cord injured more than 20 years ago
15. Body composition of spinal cord injured adults
16. Noninflammatory knee joint effusions in spinal cord injured and other paralyzed patients: Four case studies
17. The Stockholm spinal cord injury study. I. Medical problems in a regional SCI population
18. Effects of functional electrical stimulation on the joints of adolescents with spinal cord injury
19. The intra-articular effects of immobilization on the human knee
20. Heterotopic bone formation about the hip and unilateral decubitus ulcers in spinal cord injury
21. Cartilage atrophy
22. Skeletal changes in neuromuscular disorders mimicking juvenile rheumatoid arthritis and hemophilia
23. Accuracy and precision of joint space width measurements in standard and macroradiographs of osteoarthritic knees
24. Quantification of articular cartilage in the knee with pulsed saturation transfer subtraction and fat-suppressed MR-imaging: Optimization and validation
25. Accuracy of cartilage volume and thickness measurements with magnetic resonance imaging
26. Knee cartilage topography, thickness, and contact areas from MRI: In-vitro calibration and in-vivo measurements
27. Interobserver reproducibility of quantitative cartilage measurements: Comparison of B-spline snakes and manual segmentation
28. Determination of 3D cartilage thickness data from MR imaging: Computational method and reproducibility in the living
29. Effect of gradient and section orientation on quantitative analyses of knee joint cartilage
30. Patellar cartilage deformation in vivo after static versus dynamic loading
31. Precision of tibial cartilage morphometry with a coronal water-excitation MR sequence
32. Magnetic resonance imaging-based assessment of cartilage loss in severe osteoarthritis: Accuracy, precision, and diagnostic value
33. In vivo morphometry and functional analysis of human articular cartilage with quantitative magnetic resonance imaging: From image to data, from data to theory
34. Surface size, curvature analysis, and quantitative assessment of knee joint incongruity with MR imaging in vivo
35. The biological effect of continuous passive motion on the healing of full-thickness defects in articular cartilage: An experimental investigation in the rabbit