Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development

Nature Medicine

Volumn 16, Issue 6, 2010, Pages 678-686

  Saito, Taku ^a   Fukai, Atsushi ^a   Mabuchi, Akihiko ^a   Ikeda, Toshiyuki ^a   Yano, Fumiko ^a   Ohba, Shinsuke ^a   Nishida, Nao ^a   Akune, Toru ^b   Yoshimura, Noriko ^b   Nakagawa, Takumi ^a   Nakamura, Kozo ^a   Tokunaga, Katsushi ^a   Chung, Ung Il ^a   Kawaguchi, Hiroshi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 2; COLLAGENASE 3; HYPOXIA INDUCIBLE FACTOR 2ALPHA; I KAPPA B; VASCULOTROPIN A;

ARTICLE; BONE GROWTH; CARTILAGE CELL; CONTROLLED STUDY; ENCHONDRAL OSSIFICATION; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; HYDROXYLATION; MOUSE; NONHUMAN; OSTEOARTHRITIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSCRIPTION REGULATION;

AGED; AGED, 80 AND OVER; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BONE DEVELOPMENT; CASE-CONTROL STUDIES; CELLS, CULTURED; CHONDROCYTES; COLLAGEN TYPE X; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MICE; MICE, MUTANT STRAINS; MIDDLE AGED; OSTEOARTHRITIS; OSTEOARTHRITIS, KNEE; OSTEOGENESIS; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC;

MUS;

EID: 77953208836     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2146     Document Type: Article

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