-
1
-
-
0001889762
-
Proteinases and matrix degradation
-
In: Harris, E.D.Jr., Budd, R.C., Genovese, M.C., Firestein, G.S., Sargent, J.S., eds. Philadelphia, PA: Elsevier Saunders
-
Okada Y. Proteinases and matrix degradation. In:Harris ED Jr., Budd RC, Genovese MC, Firestein GS, Sargent JS, eds. Kelley's Textbook of Rheumatology, 7th edn. Philadelphia, PA:Elsevier Saunders, 2005 63 81.
-
(2005)
Kelley's Textbook of Rheumatology, 7th Edn.
, pp. 63-81
-
-
Okada, Y.1
-
2
-
-
0002656493
-
Role of endogenous proteinases in the degradation of cartilage matrix
-
In: Woessner, J.F.Jr., Howell, D.S., eds. New York: Marcel Dekker
-
Nagase H. Role of endogenous proteinases in the degradation of cartilage matrix. In:Woessner JF Jr., Howell DS, eds. Joint Cartilage Degradation. New York:Marcel Dekker, 1993 159 85.
-
(1993)
Joint Cartilage Degradation.
, pp. 159-85
-
-
Nagase, H.1
-
4
-
-
0026736030
-
Localization of matrix metalloproteinase 3 (stromelysin) in osteoarthritic cartilage and synovium
-
Okada Y, Shinmei M, Tanaka O et al. Localization of matrix metalloproteinase 3 (stromelysin) in osteoarthritic cartilage and synovium. Lab Invest 1992 66:680 90.
-
(1992)
Lab Invest
, vol.66
, pp. 680-90
-
-
Okada, Y.1
Shinmei, M.2
Tanaka, O.3
-
5
-
-
0031883781
-
Expression of matrix metalloproteinase 7 (matrilysin) in human osteoarthritic cartilage
-
Ohta S, Imai K, Yamashita K, Matsumoto T, Azumano I, Okada Y. Expression of matrix metalloproteinase 7 (matrilysin) in human osteoarthritic cartilage. Lab Invest 1998 78:79 87.
-
(1998)
Lab Invest
, vol.78
, pp. 79-87
-
-
Ohta, S.1
Imai, K.2
Yamashita, K.3
Matsumoto, T.4
Azumano, I.5
Okada, Y.6
-
6
-
-
0029880393
-
The new collagenase, collagenase-3, is expressed and synthesized by human chondrocytes but not by synoviocytes. a role in osteoarthritis
-
Reboul P, Pelletier JP, Tardif G, Cloutier JM, Martel-Pelletier J. The new collagenase, collagenase-3, is expressed and synthesized by human chondrocytes but not by synoviocytes. A role in osteoarthritis. J Clin Invest 1996 97:2011 19.
-
(1996)
J Clin Invest
, vol.97
, pp. 2011-19
-
-
Reboul, P.1
Pelletier, J.P.2
Tardif, G.3
Cloutier, J.M.4
Martel-Pelletier, J.5
-
7
-
-
0030032444
-
Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage
-
Mitchell PG, Magna HA, Reeves LM et al. Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage. J Clin Invest 1996 97:761 8.
-
(1996)
J Clin Invest
, vol.97
, pp. 761-8
-
-
Mitchell, P.G.1
Magna, H.A.2
Reeves, L.M.3
-
8
-
-
0029852094
-
Aggrecan is degraded by matrix metalloproteinases in human arthritis. Evidence that matrix metalloproteinase and aggrecanase activities can be independent
-
Fosang AJ, Last K, Maciewicz RA. Aggrecan is degraded by matrix metalloproteinases in human arthritis. Evidence that matrix metalloproteinase and aggrecanase activities can be independent. J Clin Invest 1996 98:2292 9.
-
(1996)
J Clin Invest
, vol.98
, pp. 2292-9
-
-
Fosang, A.J.1
Last, K.2
MacIewicz, R.A.3
-
9
-
-
0035884605
-
Analysis of aggrecan in human knee cartilage and synovial fluid indicates that aggrecanase (ADAMTS) activity is responsible for the catabolic turnover and loss of whole aggrecan whereas other protease activity is required for C-terminal processing in vivo
-
Sandy JD, Verscharen C. Analysis of aggrecan in human knee cartilage and synovial fluid indicates that aggrecanase (ADAMTS) activity is responsible for the catabolic turnover and loss of whole aggrecan whereas other protease activity is required for C-terminal processing in vivo. Biochem J 2001 358:615 26.
-
(2001)
Biochem J
, vol.358
, pp. 615-26
-
-
Sandy, J.D.1
Verscharen, C.2
-
10
-
-
30544448357
-
Human osteoarthritis synovial fluid and joint cartilage contain both aggrecanase- and matrix metalloproteinase-generated aggrecan fragments
-
Struglics A, Larsson S, Pratta MA, Kumar S, Lark MW, Lohmander LS. Human osteoarthritis synovial fluid and joint cartilage contain both aggrecanase- and matrix metalloproteinase-generated aggrecan fragments. Osteoarthritis Cartilage 2006 14:101 13.
-
(2006)
Osteoarthritis Cartilage
, vol.14
, pp. 101-13
-
-
Struglics, A.1
Larsson, S.2
Pratta, M.A.3
Kumar, S.4
Lark, M.W.5
Lohmander, L.S.6
-
11
-
-
0345211445
-
Purification and cloning of aggrecanase-1: A member of the ADAMTS family of proteins
-
Tortorella MD, Burn TC, Pratta MA et al. Purification and cloning of aggrecanase-1: A member of the ADAMTS family of proteins. Science 1999 284:1664 6.
-
(1999)
Science
, vol.284
, pp. 1664-6
-
-
Tortorella, M.D.1
Burn, T.C.2
Pratta, M.A.3
-
12
-
-
0033551844
-
Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family
-
43. 50.
-
Abbaszade I, Liu RQ, Yang F et al. Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family. J Biol Chem 1999 274:23 43 50.
-
(1999)
J Biol Chem
, vol.274
, pp. 23
-
-
Abbaszade, I.1
Liu, R.Q.2
Yang, F.3
-
13
-
-
30544436016
-
A contentious issue finds some clarity: On the independent and complementary roles of aggrecanase activity and MMP activity in human joint aggrecanolysis
-
Sandy JD. A contentious issue finds some clarity: On the independent and complementary roles of aggrecanase activity and MMP activity in human joint aggrecanolysis. Osteoarthritis Cartilage 2006 14:95 100.
-
(2006)
Osteoarthritis Cartilage
, vol.14
, pp. 95-100
-
-
Sandy, J.D.1
-
14
-
-
0742322761
-
ADAMTS-1, a gene product of articular chondrocytes in vivo and in vitro, is downregulated by interleukin 1β
-
Wachsmuth L, Bau B, Fan Z, Pecht A, Gerwin N, Aigner T. ADAMTS-1, a gene product of articular chondrocytes in vivo and in vitro, is downregulated by interleukin 1β. J Rheumatol 2004 31:315 20.
-
(2004)
J Rheumatol
, vol.31
, pp. 315-20
-
-
Wachsmuth, L.1
Bau, B.2
Fan, Z.3
Pecht, A.4
Gerwin, N.5
Aigner, T.6
-
15
-
-
9144230209
-
Expression profiling of metalloproteinases and their inhibitors in cartilage
-
Kevorkian L, Young DA, Darrah C et al. Expression profiling of metalloproteinases and their inhibitors in cartilage. Arthritis Rheum 2004 50:131 41.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 131-41
-
-
Kevorkian, L.1
Young, D.A.2
Darrah, C.3
-
16
-
-
0036822797
-
Relative messenger RNA expression profiling of collagenases and aggrecanases in human articular chondrocytes in vivo and in vitro
-
Bau B, Gebhard PM, Haag J, Knorr T, Bartnik E, Aigner T. Relative messenger RNA expression profiling of collagenases and aggrecanases in human articular chondrocytes in vivo and in vitro. Arthritis Rheum 2002 46:2648 57.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 2648-57
-
-
Bau, B.1
Gebhard, P.M.2
Haag, J.3
Knorr, T.4
Bartnik, E.5
Aigner, T.6
-
17
-
-
27444448206
-
Oncostatin M in combination with tumour necrosis factor α induces a chondrocyte membrane associated aggrecanase that is distinct from ADAMTS aggrecanase-1 or -2
-
Hui W, Barksby HE, Young DA, Cawston TE, McKie N, Rowan AD. Oncostatin M in combination with tumour necrosis factor α induces a chondrocyte membrane associated aggrecanase that is distinct from ADAMTS aggrecanase-1 or -2. Ann Rheum Dis 2005 64:1624 32.
-
(2005)
Ann Rheum Dis
, vol.64
, pp. 1624-32
-
-
Hui, W.1
Barksby, H.E.2
Young, D.A.3
Cawston, T.E.4
McKie, N.5
Rowan, A.D.6
-
18
-
-
3543043776
-
ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage
-
Collins-Racie LA, Flannery CR, Zeng W et al. ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage. Matrix Biol 2004 23:219 30.
-
(2004)
Matrix Biol
, vol.23
, pp. 219-30
-
-
Collins-Racie, L.A.1
Flannery, C.R.2
Zeng, W.3
-
19
-
-
0015046195
-
Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips. II. Correlation of morphology with biochemical and metabolic data
-
Mankin HJ, Dorfman H, Lippiello L, Zarins A. Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips. II. Correlation of morphology with biochemical and metabolic data. J Bone Joint Surg Am 1971 53:523 37.
-
(1971)
J Bone Joint Surg Am
, vol.53
, pp. 523-37
-
-
Mankin, H.J.1
Dorfman, H.2
Lippiello, L.3
Zarins, A.4
-
20
-
-
0022465236
-
Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee
-
Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association.
-
Altman R, Asch E, Bloch D et al. Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association. Arthritis Rheum 1986 29:1039 49.
-
(1986)
Arthritis Rheum
, vol.29
, pp. 1039-49
-
-
Altman, R.1
Asch, E.2
Bloch, D.3
-
21
-
-
33750336396
-
Tetraspanin CD151 is expressed in osteoarthritic cartilage and is involved in pericellular activation of pro-matrix metalloproteinase 7 in osteoarthritic chondrocytes
-
Fujita Y, Shiomi T, Yanagimoto S, Matsumoto H, Toyama Y, Okada Y. Tetraspanin CD151 is expressed in osteoarthritic cartilage and is involved in pericellular activation of pro-matrix metalloproteinase 7 in osteoarthritic chondrocytes. Arthritis Rheum 2006 54:3233 43.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 3233-43
-
-
Fujita, Y.1
Shiomi, T.2
Yanagimoto, S.3
Matsumoto, H.4
Toyama, Y.5
Okada, Y.6
-
22
-
-
0037222724
-
Vascular endothelial growth factor isoforms and their receptors are expressed in human osteoarthritic cartilage
-
Enomoto H, Inoki I, Komiya K et al. Vascular endothelial growth factor isoforms and their receptors are expressed in human osteoarthritic cartilage. Am J Pathol 2003 162:171 81.
-
(2003)
Am J Pathol
, vol.162
, pp. 171-81
-
-
Enomoto, H.1
Inoki, I.2
Komiya, K.3
-
23
-
-
0030951910
-
Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas
-
Ueno H, Nakamura H, Inoue M et al. Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas. Cancer Res 1997 57:2055 60.
-
(1997)
Cancer Res
, vol.57
, pp. 2055-60
-
-
Ueno, H.1
Nakamura, H.2
Inoue, M.3
-
24
-
-
3543004686
-
ADAMTS4 (aggrecanase-1) interaction with the C-terminal domain of fibronectin inhibits proteolysis of aggrecan
-
83. 91.
-
Hashimoto G, Shimoda M, Okada Y. ADAMTS4 (aggrecanase-1) interaction with the C-terminal domain of fibronectin inhibits proteolysis of aggrecan. J Biol Chem 2004 279:32 83 91.
-
(2004)
J Biol Chem
, vol.279
, pp. 32
-
-
Hashimoto, G.1
Shimoda, M.2
Okada, Y.3
-
25
-
-
0037192814
-
Activation of the proteolytic activity of ADAMTS4 (aggrecanase-1) by C-terminal truncation
-
34. 41.
-
Gao G, Westling J, Thompson VP, Howell TD, Gottschall PE, Sandy JD. Activation of the proteolytic activity of ADAMTS4 (aggrecanase-1) by C-terminal truncation. J Biol Chem 2002 277:11 34 41.
-
(2002)
J Biol Chem
, vol.277
, pp. 11
-
-
Gao, G.1
Westling, J.2
Thompson, V.P.3
Howell, T.D.4
Gottschall, P.E.5
Sandy, J.D.6
-
26
-
-
0030735269
-
Osteoarthritic lesions: Involvement of three different collagenases
-
Shlopov BV, Lie WR, Mainardi CL, Cole AA, Chubinskaya S, Hasty KA. Osteoarthritic lesions: Involvement of three different collagenases. Arthritis Rheum 1997 40:2065 74.
-
(1997)
Arthritis Rheum
, vol.40
, pp. 2065-74
-
-
Shlopov, B.V.1
Lie, W.R.2
Mainardi, C.L.3
Cole, A.A.4
Chubinskaya, S.5
Hasty, K.A.6
-
27
-
-
0030891983
-
Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage
-
Billinghurst RC, Dahlberg L, Ionescu M et al. Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage. J Clin Invest 1997 99:1534 45.
-
(1997)
J Clin Invest
, vol.99
, pp. 1534-45
-
-
Billinghurst, R.C.1
Dahlberg, L.2
Ionescu, M.3
-
28
-
-
0030875073
-
Expression of membrane-type 1 matrix metalloproteinase and activation of progelatinase a in human osteoarthritic cartilage
-
Imai K, Ohta S, Matsumoto T et al. Expression of membrane-type 1 matrix metalloproteinase and activation of progelatinase A in human osteoarthritic cartilage. Am J Pathol 1997 151:245 56.
-
(1997)
Am J Pathol
, vol.151
, pp. 245-56
-
-
Imai, K.1
Ohta, S.2
Matsumoto, T.3
-
29
-
-
18244427699
-
Selective enhancement of collagenase-mediated cleavage of resident type II collagen in cultured osteoarthritic cartilage and arrest with a synthetic inhibitor that spares collagenase 1 (matrix metalloproteinase 1)
-
Dahlberg L, Billinghurst RC, Manner P et al. Selective enhancement of collagenase-mediated cleavage of resident type II collagen in cultured osteoarthritic cartilage and arrest with a synthetic inhibitor that spares collagenase 1 (matrix metalloproteinase 1). Arthritis Rheum 2000 43:673 82.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 673-82
-
-
Dahlberg, L.1
Billinghurst, R.C.2
Manner, P.3
-
30
-
-
0034840936
-
The role of ADAM-TS4 (aggrecanase-1) and ADAM-TS5 (aggrecanase-2) in a model of cartilage degradation
-
Tortorella MD, Malfait AM, Deccico C, Arner E. The role of ADAM-TS4 (aggrecanase-1) and ADAM-TS5 (aggrecanase-2) in a model of cartilage degradation. Osteoarthritis Cartilage 2001 9:539 52.
-
(2001)
Osteoarthritis Cartilage
, vol.9
, pp. 539-52
-
-
Tortorella, M.D.1
Malfait, A.M.2
Deccico, C.3
Arner, E.4
-
31
-
-
0242580819
-
Aggrecan protects cartilage collagen from proteolytic cleavage
-
39. 45.
-
Pratta MA, Yao W, Decicco C et al. Aggrecan protects cartilage collagen from proteolytic cleavage. J Biol Chem 2003 278:45 39 45.
-
(2003)
J Biol Chem
, vol.278
, pp. 45
-
-
Pratta, M.A.1
Yao, W.2
Decicco, C.3
-
32
-
-
15844413814
-
Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis
-
Glasson SS, Askew R, Sheppard B et al. Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis. Nature 2005 434:644 8.
-
(2005)
Nature
, vol.434
, pp. 644-8
-
-
Glasson, S.S.1
Askew, R.2
Sheppard, B.3
-
33
-
-
15844384854
-
ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro
-
Stanton H, Rogerson FM, East CJ et al. ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro. Nature 2005 434:648 52.
-
(2005)
Nature
, vol.434
, pp. 648-52
-
-
Stanton, H.1
Rogerson, F.M.2
East, C.J.3
-
34
-
-
1842738084
-
Effects of transforming growth factor-β on aggrecanase production and proteoglycan degradation by human chondrocytes in vitro
-
Moulharat N, Lesur C, Thomas M et al. Effects of transforming growth factor-β on aggrecanase production and proteoglycan degradation by human chondrocytes in vitro. Osteoarthritis Cartilage 2004 12:296 305.
-
(2004)
Osteoarthritis Cartilage
, vol.12
, pp. 296-305
-
-
Moulharat, N.1
Lesur, C.2
Thomas, M.3
-
35
-
-
0035853456
-
Inhibition of ADAMTS4 (aggrecanase-1) by tissue inhibitors of metalloproteinases (TIMP-1, 2, 3 and 4)
-
Hashimoto G, Aoki T, Nakamura H, Tanzawa K, Okada Y. Inhibition of ADAMTS4 (aggrecanase-1) by tissue inhibitors of metalloproteinases (TIMP-1, 2, 3 and 4). FEBS Lett 2001 494:192 5.
-
(2001)
FEBS Lett
, vol.494
, pp. 192-5
-
-
Hashimoto, G.1
Aoki, T.2
Nakamura, H.3
Tanzawa, K.4
Okada, Y.5
-
36
-
-
0035918309
-
TIMP-3 is a potent inhibitor of aggrecanase 1 (ADAM-TS4) and aggrecanase 2 (ADAM-TS5)
-
01. 4.
-
Kashiwagi M, Tortorella M, Nagase H, Brew K. TIMP-3 is a potent inhibitor of aggrecanase 1 (ADAM-TS4) and aggrecanase 2 (ADAM-TS5). J Biol Chem 2001 276:12 01 4.
-
(2001)
J Biol Chem
, vol.276
, pp. 12
-
-
Kashiwagi, M.1
Tortorella, M.2
Nagase, H.3
Brew, K.4
-
37
-
-
33646433471
-
Regulation of the human ADAMTS-4 promoter by transcription factors and cytokines
-
Thirunavukkarasu K, Pei Y, Moore TL et al. Regulation of the human ADAMTS-4 promoter by transcription factors and cytokines. Biochem Biophys Res Commun 2006 345:197 204.
-
(2006)
Biochem Biophys Res Commun
, vol.345
, pp. 197-204
-
-
Thirunavukkarasu, K.1
Pei, Y.2
Moore, T.L.3
-
38
-
-
35148831210
-
Characterization of the human ADAMTS-5 (aggrecanase-2) gene promoter
-
Jan 8. [Epub ahead of print].
-
Thirunavukkarasu K, Pei Y, Wei T. Characterization of the human ADAMTS-5 (aggrecanase-2) gene promoter. Mol Biol Rep 2007 Jan 8 [Epub ahead of print].
-
(2007)
Mol Biol Rep
-
-
Thirunavukkarasu, K.1
Pei, Y.2
Wei, T.3
|