-
2
-
-
28844473846
-
Radical medicine: Treating ageing to cure disease
-
DOI 10.1038/nrm1763
-
Finkel T. Radical medicine: treating ageing to cure disease. Nat Rev Mol Cell Biol 2005;6:971-976 (Pubitemid 41778716)
-
(2005)
Nature Reviews Molecular Cell Biology
, vol.6
, Issue.12
, pp. 971-976
-
-
Finkel, T.1
-
3
-
-
3142740860
-
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
-
DOI 10.1126/science.1099196
-
Cohen HY, Miller C, Bitterman KJ, Wall NR, Hekking B, Kessler B, et al. Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science 2004;305:390-392 (Pubitemid 38938153)
-
(2004)
Science
, vol.305
, Issue.5682
, pp. 390-392
-
-
Cohen, H.Y.1
Miller, C.2
Bitterman, K.J.3
Wall, N.R.4
Hekking, B.5
Kessler, B.6
Howitz, K.T.7
Gorospe, M.8
De Cabo, R.9
Sinclair, D.A.10
-
4
-
-
0037238101
-
Cellular senescence and apoptosis: How cellular responses might influence aging phenotypes
-
DOI 10.1016/S0531-5565(02)00152-3, PII S0531556502001523
-
Campisi J. Cellular senescence and apoptosis: how cellular responses might influence aging phenotypes. Exp Gerontol 2003;38:5-11. (Pubitemid 36110494)
-
(2003)
Experimental Gerontology
, vol.38
, Issue.1-2
, pp. 5-11
-
-
Campisi, J.1
-
5
-
-
0033929763
-
Apoptosis in the aging process
-
Higami Y, Shimokawa I. Apoptosis in the aging process. Cell Tissue Res 2000;301:125-132
-
(2000)
Cell Tissue Res
, vol.301
, pp. 125-132
-
-
Higami, Y.1
Shimokawa, I.2
-
6
-
-
7744229575
-
Characterization of mature vs aged rabbit articular cartilage: Analysis of cell density, apoptosis-related gene expression and mechanisms controlling chondrocyte apoptosis
-
DOI 10.1016/j.joca.2004.08.003, PII S1063458404001566
-
Todd Allen R, Robertson CM, Harwood FL, Sasho T, Williams SK, Pomerleau AC, et al. Characterization of mature vs aged rabbit articular cartilage: analysis of cell density, apoptosis-related gene expression and mechanisms controlling chondrocyte apoptosis. Osteoarthritis Cartilage 2004;12:917-923 (Pubitemid 39462607)
-
(2004)
Osteoarthritis and Cartilage
, vol.12
, Issue.11
, pp. 917-923
-
-
Allen, R.T.1
Robertson, C.M.2
Harwood, F.L.3
Sasho, T.4
Williams, S.K.5
Pomerleau, B.A.6
Amiel, D.7
-
7
-
-
0016296555
-
Quantitative histological changes in osteoarthritic hip cartilage: Morphometric analysis of 29 osteoarthritic and 26 normal human femoral heads
-
Vignon E, Arlot M, Meunier P, Vignon G. Quantitative histological changes in osteoarthritic hip cartilage: morphometric analysis of 29 osteoarthritic and 26 normal human femoral heads. Clin Orthop Relat Res 1974;269-278
-
(1974)
Clin Orthop Relat Res
, pp. 269-278
-
-
Vignon, E.1
Arlot, M.2
Meunier, P.3
Vignon, G.4
-
8
-
-
0031886742
-
Osteoarthritis chondrocytes die by apoptosis: A possible pathway for osteoarthritis pathology
-
DOI 10.1002/1529-0131(199802)41:2<284::AID-ART12>3.0.CO;2-T
-
Blanco FJ, Guitian R, Vazquez-Martul E, de Toro FJ, Galdo F. Osteoarthritis chondrocytes die by apoptosis: a possible pathway for osteoarthritis pathology. Arthritis Rheum 1998;41:284-289 (Pubitemid 28087696)
-
(1998)
Arthritis and Rheumatism
, vol.41
, Issue.2
, pp. 284-289
-
-
Blanco, F.J.1
Guitian, R.2
Vazquez-Martul, E.3
De Toro, F.J.4
Galdo, F.5
-
9
-
-
0037523033
-
Apoptotic chondrocyte death in human osteoarthritis
-
Kim HA, Lee YJ, Seong SC, Choe KW, Song YW. Apoptotic chondrocyte death in human osteoarthritis. J Rheumatol 2000;27:455-462 (Pubitemid 30095481)
-
(2000)
Journal of Rheumatology
, vol.27
, Issue.2
, pp. 455-462
-
-
Kim, H.A.1
Lee, Y.J.2
Seong, S.-C.3
Choe, K.W.4
Song, Y.W.5
-
10
-
-
34447119750
-
Mechanisms of Disease: Role of chondrocytes in the pathogenesis of osteoarthritis - Structure, chaos and senescence
-
DOI 10.1038/ncprheum0534, PII NCPRHEUM0534
-
Aigner T, Soder S, Gebhard PM, McAlinden A, Haag J. Mechanisms of disease: role of chondrocytes in the pathogenesis of osteoarthritis - structure, chaos and senescence. Nat Clin Pract Rheumatol 2007;3:391-399 (Pubitemid 47034540)
-
(2007)
Nature Clinical Practice Rheumatology
, vol.3
, Issue.7
, pp. 391-399
-
-
Aigner, T.1
Soder, S.2
Gebhard, P.M.3
McAlinden, A.4
Haag, J.5
-
11
-
-
0031658981
-
Linkage of chondrocyte apoptosis and cartilage degradation in human osteoarthritis
-
DOI 10.1002/1529-0131(199809)41:9<1632::AID-ART14>3.0.CO;2-A
-
Hashimoto S, Ochs RL, Komiya S, Lotz M. Linkage of chondrocyte apoptosis and cartilage degradation in human osteoarthritis. Arthritis Rheum 1998;41:1632-1638 (Pubitemid 28459922)
-
(1998)
Arthritis and Rheumatism
, vol.41
, Issue.9
, pp. 1632-1638
-
-
Hashimoto, S.1
Ochs, R.L.2
Komiya, S.3
Lotz, M.4
-
12
-
-
17144429302
-
Calorie restriction, SIRT1 and metabolism: Understanding longevity
-
Bordone L, Guarente L. Calorie restriction, SIRT1 and metabolism: understanding longevity. Nat Rev Mol Cell Biol 2005;6:298-305.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 298-305
-
-
Bordone, L.1
Guarente, L.2
-
13
-
-
0034193776
-
Sir2 links chromatin silencing, metabolism, and aging
-
Guarente L. Sir2 links chromatin silencing, metabolism, and aging. Genes Dev 2000;14:1021-1026 (Pubitemid 30324417)
-
(2000)
Genes and Development
, vol.14
, Issue.9
, pp. 1021-1026
-
-
Guarente, L.1
-
14
-
-
0034677535
-
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
-
DOI 10.1038/35001622
-
Imai S, Armstrong CM, Kaeberlein M, Guarente L. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 2000;403:795-800. (Pubitemid 30111843)
-
(2000)
Nature
, vol.403
, Issue.6771
, pp. 795-800
-
-
Imai, S.-I.1
Armstrong, C.M.2
Kaeberlein, M.3
Guarente, L.4
-
15
-
-
0034703217
-
Requirement of NAD and SIR2 for life-span extension by calorie restriction in saccharomyces cerevisiae
-
DOI 10.1126/science.289.5487.2126
-
Lin SJ, Defossez PA, Guarente L. Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science 2000;289:2126-2128 (Pubitemid 30736519)
-
(2000)
Science
, vol.289
, Issue.5487
, pp. 2126-2128
-
-
Lin, S.-J.1
Defossez, P.-A.2
Guarente, L.3
-
16
-
-
0035913911
-
Negative control of p53 by Sir2α promotes cell survival under stress
-
DOI 10.1016/S0092-8674(01)00524-4
-
Luo J, Nikolaev AY, Imai S, Chen D, Su F, Shiloh A, et al. Negative control of p53 by Sir2α promotes cell survival under stress. Cell 2001;107:137-148 (Pubitemid 33035941)
-
(2001)
Cell
, vol.107
, Issue.2
, pp. 137-148
-
-
Luo, J.1
Nikolaev, A.Y.2
Imai, S.-I.3
Chen, D.4
Su, F.5
Shiloh, A.6
Guarente, L.7
Gu, W.8
-
17
-
-
0035913903
-
SIRT1 functions as an NAD-dependent p53 deacetylase
-
DOI 10.1016/S0092-8674(01)00527-X
-
Vaziri H, Dessain SK, Ng Eaton E, Imai SI, Frye RA, Pandita TK, et al. hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 2001;107:149-159 (Pubitemid 33035942)
-
(2001)
Cell
, vol.107
, Issue.2
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Eaton, E.N.3
Imai, S.-I.4
Frye, R.A.5
Pandita, T.K.6
Guarente, L.7
Weinberg, R.A.8
-
18
-
-
1342264308
-
Mammalian SIRT1 Represses Forkhead Transcription Factors
-
DOI 10.1016/S0092-8674(04)00126-6
-
Motta MC, Divecha N, Lemieux M, Kamel C, Chen D, Gu W, et al. Mammalian SIRT1 represses forkhead transcription factors. Cell 2004;116:551-563 (Pubitemid 38264432)
-
(2004)
Cell
, vol.116
, Issue.4
, pp. 551-563
-
-
Motta, M.C.1
Divecha, N.2
Lemieux, M.3
Kamel, C.4
Chen, D.5
Gu, W.6
Bultsma, Y.7
McBurney, M.8
Guarente, L.9
-
19
-
-
3242719545
-
Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase
-
DOI 10.1038/sj.emboj.7600244
-
Yeung F, Hoberg JE, Ramsey CS, Keller MD, Jones DR, Frye RA, et al. Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J 2004;23:2369-2380 (Pubitemid 38954844)
-
(2004)
EMBO Journal
, vol.23
, Issue.12
, pp. 2369-2380
-
-
Yeung, F.1
Hoberg, J.E.2
Ramsey, C.S.3
Keller, M.D.4
Jones, D.R.5
Frye, R.A.6
Mayo, M.W.7
-
20
-
-
34249669270
-
Sirt1 regulates aging and resistance to oxidative stress in the heart
-
DOI 10.1161/01.RES.0000267723.65696.4a
-
Alcendor RR, Gao S, Zhai P, Zablocki D, Holle E, Yu X, et al. Sirt1 regulates aging and resistance to oxidative stress in the heart. Circ Res 2007;100:1512-1521 (Pubitemid 46834764)
-
(2007)
Circulation Research
, vol.100
, Issue.10
, pp. 1512-1521
-
-
Alcendor, R.R.1
Gao, S.2
Zhai, P.3
Zablocki, D.4
Holle, E.5
Yu, X.6
Tian, B.7
Wagner, T.8
Vatner, S.F.9
Sadoshima, J.10
-
21
-
-
8844247034
-
Silent information regulator 2α, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes
-
DOI 10.1161/01.RES.0000147557.75257.ff
-
Alcendor RR, Kirshenbaum LA, Imai S, Vatner SF, Sadoshima J. Silent information regulator 2α, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes. Circ Res 2004;95:971-980 (Pubitemid 39532327)
-
(2004)
Circulation Research
, vol.95
, Issue.10
, pp. 971-980
-
-
Alcendor, R.R.1
Kirshenbaum, L.A.2
Imai, S.-I.3
Vatner, S.F.4
Sadoshima, J.5
-
22
-
-
4043165678
-
Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration
-
DOI 10.1126/science.1098014
-
Araki T, Sasaki Y, Milbrandt J. Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration. Science 2004;305:1010-1013 (Pubitemid 39071777)
-
(2004)
Science
, vol.305
, Issue.5686
, pp. 1010-1013
-
-
Araki, T.1
Sasaki, Y.2
Milbrandt, J.3
-
23
-
-
0035136052
-
Hydrogen peroxide induces apoptosis of chondrocytes; involvement of calcium ion and extracellular signal-regulated protein kinase
-
DOI 10.1007/s000110050719
-
Asada S, Fukuda K, Nishisaka F, Matsukawa M, Hamanisi C. Hydrogen peroxide induces apoptosis of chondrocytes; involvement of calcium ion and extracellular signal-regulated protein kinase. Inflamm Res 2001;50:19-23. (Pubitemid 32156114)
-
(2001)
Inflammation Research
, vol.50
, Issue.1
, pp. 19-23
-
-
Asada, S.1
Fukuda, K.2
Nishisaka, F.3
Matsukawa, M.4
Hamanisi, C.5
-
24
-
-
0034096906
-
Effects of shear stress on articular chondrocyte metabolism
-
Lane Smith R, Trindade MC, Ikenoue T, Mohtai M, Das P, Carter DR, et al. Effects of shear stress on articular chondrocyte metabolism. Biorheology 2000;37:95-107. (Pubitemid 30353539)
-
(2000)
Biorheology
, vol.37
, Issue.1-2
, pp. 95-107
-
-
Lane Smith, R.1
Trindade, M.C.D.2
Ikenoue, T.3
Mohtai, M.4
Das, P.5
Carter, D.R.6
Goodman, S.B.7
Schurman, D.J.8
-
25
-
-
0042822155
-
Regulation of nitric oxide and bcl-2 expression by shear stress in human osteoarthritic chondrocytes in vitro
-
DOI 10.1002/jcb.10611
-
Lee MS, Trindade MC, Ikenoue T, Goodman SB, Schurman DJ, Smith RL. Regulation of nitric oxide and bcl-2 expression by shear stress in human osteoarthritic chondrocytes in vitro. J Cell Biochem 2003;90:80-86 (Pubitemid 37052311)
-
(2003)
Journal of Cellular Biochemistry
, vol.90
, Issue.1
, pp. 80-86
-
-
Lee, M.S.1
Trindade, M.C.D.2
Ikenoue, T.3
Goodman, S.B.4
Schurman, D.J.5
Smith, R.L.6
-
26
-
-
25144473083
-
Erratum: Catabolic stress induces expression of hypoxia-iducible factor (HIF)-1α in articular chondrocytes: Involvement of HIF-1α in the pathogenesis of osteoarthritis (Arthritis Research and Therapy)
-
DOI 10.1186/ar1822
-
Yudoh K, Nakamura H, Masuko-Hongo K, Kato T, Nishioka K. Catabolic stress induces expression of hypoxia-inducible factor (HIF)-1α in articular chondrocytes: involvement of HIF-1α in the pathogenesis of osteoarthritis [published erratum appears in Arthritis Res Ther 2005;7:225]. Arthritis Res Ther 2005;7:R904-14. (Pubitemid 41335159)
-
(2005)
Arthritis Research and Therapy
, vol.7
, Issue.5
, pp. 225
-
-
Yudoh, K.1
Nakamura, H.2
Masuko-Hongo, K.3
Kato, T.4
Nishioka, K.5
-
27
-
-
33646820649
-
Prolactin inhibits the apoptosis of chondrocytes induced by serum starvation
-
DOI 10.1677/joe.1.06766
-
Zermeno C, Guzman-Morales J, Macotela Y, Nava G, Lopez-Barrera F, Kouri JB, et al. Prolactin inhibits the apoptosis of chondrocytes induced by serum starvation. J Endocrinol 2006;189:R1-8. (Pubitemid 43757798)
-
(2006)
Journal of Endocrinology
, vol.189
, Issue.2
-
-
Zermeno, C.1
Guzman-Morales, J.2
Macotela, Y.3
Nava, G.4
Lopez-Barrera, F.5
Kouri, J.B.6
Lavalle, C.7
Martinez De La Escalera, G.8
Clapp, C.9
-
28
-
-
0037975689
-
Hsp70 prevents nitric oxide-induced apoptosis in articular chondrocytes
-
DOI 10.1002/art.11040
-
Terauchi R, Takahashi KA, Arai Y, Ikeda T, Ohashi S, Imanishi J, et al. Hsp70 prevents nitric oxide-induced apoptosis in articular chondrocytes. Arthritis Rheum 2003;48:1562-1568 (Pubitemid 36682364)
-
(2003)
Arthritis and Rheumatism
, vol.48
, Issue.6
, pp. 1562-1568
-
-
Terauchi, R.1
Takahashi, K.A.2
Arai, Y.3
Ikeda, T.4
Ohashi, S.5
Imanishi, J.6
Mazda, O.7
Kubo, T.8
-
29
-
-
0031837375
-
Chondrocyte apoptosis and nitric oxide production during experimentally induced osteoarthritis
-
DOI 10.1002/1529-0131(199807)41:7<1266::AID-ART18>3.0.CO;2-Y
-
Hashimoto S, Takahashi K, Amiel D, Coutts RD, Lotz M. Chondrocyte apoptosis and nitric oxide production during experimentally induced osteoarthritis. Arthritis Rheum 1998;41:1266-1274 (Pubitemid 28313430)
-
(1998)
Arthritis and Rheumatism
, vol.41
, Issue.7
, pp. 1266-1274
-
-
Hashimoto, S.1
Takahashi, K.2
Amiel, D.3
Coutts, R.D.4
Lotz, M.5
-
30
-
-
0035914304
-
Identification of a Class of Small Molecule Inhibitors of the Sirtuin Family of NAD-dependent Deacetylases by Phenotypic Screening
-
DOI 10.1074/jbc.M106779200
-
Grozinger CM, Chao ED, Blackwell HE, Moazed D, Schreiber SL. Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening. J Biol Chem 2001;276:38837-38843 (Pubitemid 37371246)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.42
, pp. 38837-38843
-
-
Grozinger, C.M.1
Chao, E.D.2
Blackwell, H.E.3
Moazed, D.4
Schreiber, S.L.5
-
31
-
-
0037160097
-
Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast Sir2 and human SIRT1
-
DOI 10.1074/jbc.M205670200
-
Bitterman KJ, Anderson RM, Cohen HY, Latorre-Esteves M, Sinclair DA. Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1. J Biol Chem 2002;277:45099-45107 (Pubitemid 36159111)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.47
, pp. 45099-45107
-
-
Bitterman, K.J.1
Anderson, R.M.2
Cohen, H.Y.3
Latorre-Esteves, M.4
Sinclair, D.A.5
-
32
-
-
0141719702
-
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
-
DOI 10.1038/nature01960
-
Howitz KT, Bitterman KJ, Cohen HY, Lamming DW, Lavu S, Wood JG, et al. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 2003;425:191-196 (Pubitemid 37150899)
-
(2003)
Nature
, vol.425
, Issue.6954
, pp. 191-196
-
-
Howitz, K.T.1
Bitterman, K.J.2
Cohen, H.Y.3
Lamming, D.W.4
Lavu, S.5
Wood, J.G.6
Zipkin, R.E.7
Chung, P.8
Kisielewski, A.9
Zhang, L.-L.10
Scherer, B.11
Sinclair, D.A.12
-
33
-
-
26244436281
-
Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins
-
DOI 10.1091/mbc.E05-01-0033
-
Michishita E, Park JY, Burneskis JM, Barrett JC, Horikawa I. Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins. Mol Biol Cell 2005;16:4623-4635 (Pubitemid 41416446)
-
(2005)
Molecular Biology of the Cell
, vol.16
, Issue.10
, pp. 4623-4635
-
-
Michishita, E.1
Park, J.Y.2
Burneskis, J.M.3
Barrett, J.C.4
Horikawa, I.5
-
34
-
-
0037179714
-
A putative lipid transfer protein involved in systemic resistance signalling in Arabidopsis
-
Maldonado AM, Doerner P, Dixon RA, Lamb CJ, Cameron RK. A putative lipid transfer protein involved in systemic resistance signalling in Arabidopsis. Nature 2002;419:399-403.
-
(2002)
Nature
, vol.419
, pp. 399-403
-
-
Maldonado, A.M.1
Doerner, P.2
Dixon, R.A.3
Lamb, C.J.4
Cameron, R.K.5
-
35
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES, et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997;91:479-489 (Pubitemid 27508237)
-
(1997)
Cell
, vol.91
, Issue.4
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
Wang, X.7
-
36
-
-
61349159991
-
Regulation of cartilage-specific gene expression in human chondrocytes by SirT1 and nicotinamide phosphoribosyltransferase
-
Dvir-Ginzberg M, Gagarina V, Lee EJ, Hall DJ. Regulation of cartilage-specific gene expression in human chondrocytes by SirT1 and nicotinamide phosphoribosyltransferase. J Biol Chem 2008;283:36300-36310
-
(2008)
J Biol Chem
, vol.283
, pp. 36300-36310
-
-
Dvir-Ginzberg, M.1
Gagarina, V.2
Lee, E.J.3
Hall, D.J.4
-
37
-
-
33745166337
-
Silent information regulator 2 (SIRT1) attenuates oxidative stress-induced mesangial cell apoptosis via p53 deacetylation
-
DOI 10.1016/j.freeradbiomed.2006.02.014, PII S0891584906001249
-
Kume S, Haneda M, Kanasaki K, Sugimoto T, Araki S, Isono M, et al. Silent information regulator 2 (SIRT1) attenuates oxidative stress-induced mesangial cell apoptosis via p53 deacetylation. Free Radic Biol Med 2006;40:2175-2182 (Pubitemid 43903102)
-
(2006)
Free Radical Biology and Medicine
, vol.40
, Issue.12
, pp. 2175-2182
-
-
Kume, S.1
Haneda, M.2
Kanasaki, K.3
Sugimoto, T.4
Araki, S.-I.5
Isono, M.6
Isshiki, K.7
Uzu, T.8
Kashiwagi, A.9
Koya, D.10
-
38
-
-
10844236451
-
Nutrient availability regulates SIRT1 through a forkhead-dependent pathway
-
DOI 10.1126/science.1101731
-
Nemoto S, Fergusson MM, Finkel T. Nutrient availability regulates SIRT1 through a forkhead-dependent pathway. Science 2004;306:2105-2108 (Pubitemid 40007664)
-
(2004)
Science
, vol.306
, Issue.5704
, pp. 2105-2108
-
-
Nemoto, S.1
Fergusson, M.M.2
Finkel, T.3
-
39
-
-
0141814680
-
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice
-
DOI 10.1073/pnas.1934713100
-
Cheng HL, Mostoslavsky R, Saito S, Manis JP, Gu Y, Patel P, et al. Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc Natl Acad Sci U S A 2003;100:10794-10799 (Pubitemid 37140107)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.19
, pp. 10794-10799
-
-
Cheng, H.-L.1
Mostoslavsky, R.2
Saito, S.3
Manis, J.P.4
Gu, Y.5
Patel, P.6
Bronson, R.7
Appella, E.8
Alt, F.W.9
Chua, K.F.10
-
40
-
-
28544444366
-
Cancer-specific functions of SIRT1 enable human epithelial cancer cell growth and survival
-
DOI 10.1158/0008-5472.CAN-05-1923
-
Ford J, Jiang M, Milner J. Cancer-specific functions of SIRT1 enable human epithelial cancer cell growth and survival. Cancer Res 2005;65:10457-10463 (Pubitemid 41743740)
-
(2005)
Cancer Research
, vol.65
, Issue.22
, pp. 10457-10463
-
-
Ford, J.1
Jiang, M.2
Milner, J.3
-
41
-
-
33845501864
-
Apoptosome: A platform for the activation of initiator caspases
-
DOI 10.1038/sj.cdd.4402028, PII 4402028
-
Bao Q, Shi Y. Apoptosome: a platform for the activation of initiator caspases. Cell Death Differ 2007;14:56-65. (Pubitemid 44911894)
-
(2007)
Cell Death and Differentiation
, vol.14
, Issue.1
, pp. 56-65
-
-
Bao, Q.1
Shi, Y.2
-
42
-
-
34247497716
-
Embedded together: The life and death consequences of interaction of the Bcl-2 family with membranes
-
DOI 10.1007/s10495-007-0746-4, Special Issue on Mitochondria in Apoptosis
-
Leber B, Lin J, Andrews DW. Embedded together: the life and death consequences of interaction of the Bcl-2 family with membranes. Apoptosis 2007;12:897-911. (Pubitemid 46653294)
-
(2007)
Apoptosis
, vol.12
, Issue.5
, pp. 897-911
-
-
Leber, B.1
Lin, J.2
Andrews, D.W.3
-
43
-
-
0034640281
-
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
-
DOI 10.1126/science.288.5468.1053
-
Oda E, Ohki R, Murasawa H, Nemoto J, Shibue T, Yamashita T, et al. Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science 2000;288:1053-1058 (Pubitemid 30324238)
-
(2000)
Science
, vol.288
, Issue.5468
, pp. 1053-1058
-
-
Oda, E.1
Ohki, R.2
Murasawa, H.3
Nemoto, J.4
Shibue, T.5
Yamashita, T.6
Tokino, T.7
Taniguchi, T.8
Tanaka, N.9
-
44
-
-
2342632422
-
Resveratrol inhibits the release of mediators from bone marrow-derived mouse mast cells in vitro
-
DOI 10.1055/s-2004-818940
-
Baolin L, Inami Y, Tanaka H, Inagaki N, Iinuma M, Nagai H. Resveratrol inhibits the release of mediators from bone marrow-derived mouse mast cells in vitro. Planta Med 2004;70:305-309 (Pubitemid 38594600)
-
(2004)
Planta Medica
, vol.70
, Issue.4
, pp. 305-309
-
-
Baolin, L.1
Inami, Y.2
Tanaka, H.3
Inagaki, N.4
Iinuma, M.5
Nagai, H.6
-
45
-
-
0042744823
-
Resveratrol blocks interleukin-1β-induced activation of the nuclear transcription factor NF-κB, inhibits proliferation, causes S-phase arrest, and induces apoptosis of acute myeloid leukemia cells
-
DOI 10.1182/blood-2002-11-3550
-
Estrov Z, Shishodia S, Faderl S, Harris D, Van Q, Kantarjian HM, et al. Resveratrol blocks interleukin-1β-induced activation of the nuclear transcription factor NF-κB, inhibits proliferation, causes S-phase arrest, and induces apoptosis of acute myeloid leukemia cells. Blood 2003;102:987-995 (Pubitemid 36917794)
-
(2003)
Blood
, vol.102
, Issue.3
, pp. 987-995
-
-
Estrov, Z.1
Shishodia, S.2
Faderl, S.3
Harris, D.4
Van, Q.5
Kantarjian, H.M.6
Talpaz, M.7
Aggarwal, B.B.8
-
46
-
-
0034103188
-
Resveratrol selectively inhibits leukemia cells: A prospective agent for ex vivo bone marrow purging
-
Gautam SC, Xu YX, Dumaguin M, Janakiraman N, Chapman RA. Resveratrol selectively inhibits leukemia cells: a prospective agent for ex vivo bone marrow purging. Bone Marrow Transplant 2000;25:639-645 (Pubitemid 30156589)
-
(2000)
Bone Marrow Transplantation
, vol.25
, Issue.6
, pp. 639-645
-
-
Gautam, S.C.1
Xu, Y.X.2
Dumaguin, M.3
Janakiraman, N.4
Chapman, R.A.5
-
47
-
-
3242810643
-
In vitro effects of the polyphenols resveratrol, mangiferin and (-)-epigallocatechin-3-gallate on the scuticociliate fish pathogen Philasterides dicentrarchi
-
Leiro J, Arranz JA, Parama A, Alvarez MF, Sanmartin ML. In vitro effects of the polyphenols resveratrol, mangiferin and (-)-epigallocatechin-3-gallate on the scuticociliate fish pathogen Philasterides dicentrarchi. Dis Aquat Organ 2004;59:171-174
-
(2004)
Dis Aquat Organ
, vol.59
, pp. 171-174
-
-
Leiro, J.1
Arranz, J.A.2
Parama, A.3
Alvarez, M.F.4
Sanmartin, M.L.5
-
48
-
-
51849141393
-
The antioxidant resveratrol protects against chondrocyte apoptosis via effects on mitochondrial polarization and ATP production
-
Dave M, Attur M, Palmer G, Al-Mussawir HE, Kennish L, Patel J, et al. The antioxidant resveratrol protects against chondrocyte apoptosis via effects on mitochondrial polarization and ATP production. Arthritis Rheum 2008;58:2786-2797
-
(2008)
Arthritis Rheum
, vol.58
, pp. 2786-2797
-
-
Dave, M.1
Attur, M.2
Palmer, G.3
Al-Mussawir, H.E.4
Kennish, L.5
Patel, J.6
-
49
-
-
34247880271
-
Resveratrol inhibits IL-1β-induced stimulation of caspase-3 and cleavage of PARP in human articular chondrocytes in vitro
-
DOI 10.1196/annals.1397.060, Signal Transduction Pathways, Part C: Cell Signaling in Health and Disease
-
Shakibaei M, John T, Seifarth C, Mobasheri A. Resveratrol inhibits IL-1β-induced stimulation of caspase-3 and cleavage of PARP in human articular chondrocytes in vitro. Ann N Y Acad Sci 2007;1095:554-563 (Pubitemid 47092487)
-
(2007)
Annals of the New York Academy of Sciences
, vol.1095
, pp. 554-563
-
-
Shakibaei, M.1
John, T.2
Seifarth, C.3
Mobasheri, A.4
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