메뉴 건너뛰기




Volumn APR, Issue , 2011, Pages

Mitochondrial approaches to protect against cardiac ischemia and reperfusion injury

Author keywords

Cardiac ischemia reperfusion; Cardiac metabolism; Mitochondria; Mitochondrial ca 2+; Nitric oxide; Peroxynitrite; Reactive oxygen species; Therapy

Indexed keywords


EID: 80054978144     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2011.00013     Document Type: Article
Times cited : (124)

References (358)
  • 2
    • 84928589726 scopus 로고    scopus 로고
    • Ranolazine, a late sodium current inhibitor, reduces ischemia-induced superoxide emission and improves functional recovery in guinea pig hearts
    • Aldakkak, M., Heisner, J. S., Camara, A. K. S., Haumann, J., and Stowe, D. F. (2009). Ranolazine, a late sodium current inhibitor, reduces ischemia-induced superoxide emission and improves functional recovery in guinea pig hearts. FASEB J. Abstract 23, 93.17.
    • (2009) FASEB J. Abstract , vol.23 , Issue.93 , pp. 17
    • Aldakkak, M.1    Heisner, J.S.2    Camara, A.K.S.3    Haumann, J.4    Stowe, D.F.5
  • 7
    • 0027181186 scopus 로고
    • Evidence that mitochondrial respiration is a source of potentially toxic oxygen free radicals in intact rabbit hearts subjected to ischemia and reflow
    • Ambrosio, G., Zweier, J. L., Duilio, C., Kuppusamy, P., Santoro, G., Elia, P. P., Tritto, I., Cirillo, P., Condorelli, M., and Chiariello, M. (1993). Evidence that mitochondrial respiration is a source of potentially toxic oxygen free radicals in intact rabbit hearts subjected to ischemia and reflow. J. Biol. Chem. 268, 18532-18541.
    • (1993) J. Biol. Chem. , vol.268 , pp. 18532-18541
    • Ambrosio, G.1    Zweier, J.L.2    Duilio, C.3    Kuppusamy, P.4    Santoro, G.5    Elia, P.P.6    Tritto, I.7    Cirillo, P.8    Condorelli, M.9    Chiariello, M.10
  • 8
    • 17144422877 scopus 로고    scopus 로고
    • Mitochondrial metabolism of reactive oxygen species
    • [Review]
    • Andreyev, A. Y., Kushnareva, Y. E., and Starkov, A. A. (2005). Mitochondrial metabolism of reactive oxygen species. Biochemistry Mosc. 70, 200-214. [Review].
    • (2005) Biochemistry Mosc , vol.70 , pp. 200-214
    • Andreyev, A.Y.1    Kushnareva, Y.E.2    Starkov, A.A.3
  • 9
    • 29344465712 scopus 로고    scopus 로고
    • Mitochondrial criticality: a new concept at the turning point of life or death
    • Aon, M. A., Cortassa, S., Akar, F. G., and O'Rourke, B. (2006a). Mitochondrial criticality: a new concept at the turning point of life or death. Biochim. Biophys. Acta 1762, 232-240.
    • (2006) Biochim. Biophys. Acta , vol.1762 , pp. 232-240
    • Aon, M.A.1    Cortassa, S.2    Akar, F.G.3    O'Rourke, B.4
  • 10
    • 33845360700 scopus 로고    scopus 로고
    • The fundamental organization of cardiac mitochondria as a network of coupled oscillators
    • Aon, M. A., Cortassa, S., and O'Rourke, B. (2006b). The fundamental organization of cardiac mitochondria as a network of coupled oscillators. Biophys. J. 91, 4317-4327.
    • (2006) Biophys. J. , vol.91 , pp. 4317-4327
    • Aon, M.A.1    Cortassa, S.2    O'Rourke, B.3
  • 11
    • 34547578624 scopus 로고    scopus 로고
    • Sequential opening of mitochondrial ion channels as a function of glutathione redox thiol status
    • Aon, M. A., Cortassa, S., Maack, C., and O'Rourke, B. (2007). Sequential opening of mitochondrial ion channels as a function of glutathione redox thiol status. J. Biol. Chem. 282, 21889-21900.
    • (2007) J. Biol. Chem. , vol.282 , pp. 21889-21900
    • Aon, M.A.1    Cortassa, S.2    Maack, C.3    O'Rourke, B.4
  • 12
    • 0242582202 scopus 로고    scopus 로고
    • Synchronized whole cell oscillations in mitochondrial metabolism triggered by a local release of reactive oxygen species in cardiac myocytes
    • Aon, M. A., Cortassa, S., Marban, E., and O'Rourke, B. (2003). Synchronized whole cell oscillations in mitochondrial metabolism triggered by a local release of reactive oxygen species in cardiac myocytes. J. Biol. Chem. 278, 44735-44744.
    • (2003) J. Biol. Chem. , vol.278 , pp. 44735-44744
    • Aon, M.A.1    Cortassa, S.2    Marban, E.3    O'Rourke, B.4
  • 13
    • 39149106144 scopus 로고    scopus 로고
    • Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1alpha-Kv1 5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer
    • Archer, S. L., Gomberg-Maitland, M., Maitland, M. L., Rich, S., Garcia, J. G., and Weir, E. K. (2008). Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1alpha-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer. Am. J. Physiol. Heart Circ. Physiol. 294, H570-H578.
    • (2008) Am. J. Physiol. Heart Circ. Physiol. , vol.294
    • Archer, S.L.1    Gomberg-Maitland, M.2    Maitland, M.L.3    Rich, S.4    Garcia, J.G.5    Weir, E.K.6
  • 14
    • 38349057828 scopus 로고    scopus 로고
    • Mitochondria-directed therapeutics
    • Armstrong, J. S. (2008). Mitochondria-directed therapeutics. Antioxid. Redox Signal. 10, 575-578.
    • (2008) Antioxid. Redox Signal. , vol.10 , pp. 575-578
    • Armstrong, J.S.1
  • 15
    • 34547590901 scopus 로고    scopus 로고
    • Metabolic mechanisms in heart failure
    • Ashrafian, H., Frenneaux, M. P., and Opie, L. H. (2007). Metabolic mechanisms in heart failure. Circulation 116, 434-448.
    • (2007) Circulation , vol.116 , pp. 434-448
    • Ashrafian, H.1    Frenneaux, M.P.2    Opie, L.H.3
  • 16
    • 0942290437 scopus 로고    scopus 로고
    • In self-defence: hexokinase promotes voltage-dependent anion channel closure and prevents mitochondria-mediated apoptotic cell death
    • Azoulay-Zohar, H., Israelson, A., Abu-Hamad, S., and Shoshan-Barmatz, V. (2004). In self-defence: hexokinase promotes voltage-dependent anion channel closure and prevents mitochondria-mediated apoptotic cell death. Biochem. J. 377(Pt 2), 347-355.
    • (2004) Biochem. J. , vol.377 , Issue.PART 2 , pp. 347-355
    • Azoulay-Zohar, H.1    Israelson, A.2    Abu-Hamad, S.3    Shoshan-Barmatz, V.4
  • 19
    • 0025343842 scopus 로고
    • Regulation of oxidative phosphorylation in the mammalian cell
    • Balaban, R. S. (1990). Regulation of oxidative phosphorylation in the mammalian cell. Am. J. Physiol. 258(Pt 1), C377-C389.
    • (1990) Am. J. Physiol. , vol.258 , Issue.PART 1
    • Balaban, R.S.1
  • 20
    • 0022505605 scopus 로고
    • Relation between work and phosphate metabolite in the in vivo paced mammalian heart
    • Balaban, R. S., Kantor, H. L., Katz, L. A., and Briggs, R. W. (1986). Relation between work and phosphate metabolite in the in vivo paced mammalian heart. Science 232, 1121-1123.
    • (1986) Science , vol.232 , pp. 1121-1123
    • Balaban, R.S.1    Kantor, H.L.2    Katz, L.A.3    Briggs, R.W.4
  • 22
    • 21244446551 scopus 로고    scopus 로고
    • Properties of the permeability transition pore in mitochondria devoid of cyclophilin D
    • Basso, E., Fante, L., Fowlkes, J., Petronilli, V., Forte, M. A., and Bernardi, P. (2005). Properties of the permeability transition pore in mitochondria devoid of cyclophilin D. J. Biol. Chem. 280, 18558-18561.
    • (2005) J. Biol. Chem. , vol.280 , pp. 18558-18561
    • Basso, E.1    Fante, L.2    Fowlkes, J.3    Petronilli, V.4    Forte, M.A.5    Bernardi, P.6
  • 23
    • 0035235476 scopus 로고    scopus 로고
    • Neuroprotective abilities of resveratrol and other red wine constituents against nitric oxide-related toxicity in cultured hippocampal neurons
    • Bastianetto, S., Zheng, W. H., and Quirion, R. (2000). Neuroprotective abilities of resveratrol and other red wine constituents against nitric oxide-related toxicity in cultured hippocampal neurons. Br. J. Pharmacol. 131, 711-720.
    • (2000) Br. J. Pharmacol. , vol.131 , pp. 711-720
    • Bastianetto, S.1    Zheng, W.H.2    Quirion, R.3
  • 24
    • 59649125035 scopus 로고    scopus 로고
    • Cardioprotection by hydrogen sulfide: suspended animation, inflammation, and apoptosis
    • Baumgart, K., Georgieff, M., Radermacher, P., and Calzia, E. (2009). Cardioprotection by hydrogen sulfide: suspended animation, inflammation, and apoptosis. Shock 31, 218-219.
    • (2009) Shock , vol.31 , pp. 218-219
    • Baumgart, K.1    Georgieff, M.2    Radermacher, P.3    Calzia, E.4
  • 25
    • 77953717010 scopus 로고    scopus 로고
    • Modification of myocardial substrate utilisation: a new therapeutic paradigm in cardiovascular disease
    • Beadle, R. M., and Frenneaux, M. (2010). Modification of myocardial substrate utilisation: a new therapeutic paradigm in cardiovascular disease. Heart 96, 824-830.
    • (2010) Heart , vol.96 , pp. 824-830
    • Beadle, R.M.1    Frenneaux, M.2
  • 26
    • 33749339635 scopus 로고    scopus 로고
    • Modeling of oxygen transport and cellular energetics explains observations on in vivo cardiac energy metabolism
    • doi: 10.1371/ journal.pcbi.0020107
    • Beard, D. A. (2006). Modeling of oxygen transport and cellular energetics explains observations on in vivo cardiac energy metabolism. PLoS Comput. Biol. 2, e107. doi: 10.1371/ journal.pcbi.0020107
    • (2006) PLoS Comput. Biol. , vol.2
    • Beard, D.A.1
  • 27
    • 70049116237 scopus 로고    scopus 로고
    • Strong inference for systems biology
    • doi: 10.1371/journal.pcbi.1000459
    • Beard, D. A., and Kushmerick, M. J. (2009). Strong inference for systems biology. PLoS Comput. Biol. 5, e1000459. doi: 10.1371/journal.pcbi.1000459
    • (2009) PLoS Comput. Biol. , vol.5
    • Beard, D.A.1    Kushmerick, M.J.2
  • 29
    • 0032211437 scopus 로고    scopus 로고
    • Critical evaluation of the use of hydroethidine as a measure of superoxide anion radical
    • Benov, L., Sztejnberg, L., and Fridovich, I. (1998). Critical evaluation of the use of hydroethidine as a measure of superoxide anion radical. Free Radic. Biol. Med. 25, 826-831.
    • (1998) Free Radic. Biol. Med. , vol.25 , pp. 826-831
    • Benov, L.1    Sztejnberg, L.2    Fridovich, I.3
  • 30
    • 67650691143 scopus 로고    scopus 로고
    • Mitochondrial dynamics in heart cells: very low amplitude high frequency fluctuations in adult cardiomyocytes and flow motion in non beating Hl-1 cells
    • Beraud, N., Pelloux, S., Usson, Y., Kuznetsov, A. V., Ronot, X., Tourneur, Y., and Saks, V. (2009). Mitochondrial dynamics in heart cells: very low amplitude high frequency fluctuations in adult cardiomyocytes and flow motion in non beating Hl-1 cells. J. Bioenerg. Biomembr. 41, 195-214.
    • (2009) J. Bioenerg. Biomembr. , vol.41 , pp. 195-214
    • Beraud, N.1    Pelloux, S.2    Usson, Y.3    Kuznetsov, A.V.4    Ronot, X.5    Tourneur, Y.6    Saks, V.7
  • 31
    • 0030807891 scopus 로고    scopus 로고
    • Dichloroacetate as metabolic therapy for myocardial ischemia and failure
    • Bersin, R. M., and Stacpoole, P. W. (1997). Dichloroacetate as metabolic therapy for myocardial ischemia and failure. Am. Heart J. 134(Pt 1), 841-855.
    • (1997) Am. Heart J. , vol.134 , Issue.PART 1 , pp. 841-855
    • Bersin, R.M.1    Stacpoole, P.W.2
  • 32
    • 31144468478 scopus 로고    scopus 로고
    • Role of hydrogen sulfide in the cardioprotection caused by ischemic preconditioning in the rat heart and cardiac myocytes
    • Bian, J. S., Yong, Q. C., Pan, T. T., Feng, Z. N., Ali, M. Y., Zhou, S., and Moore, P. K. (2006). Role of hydrogen sulfide in the cardioprotection caused by ischemic preconditioning in the rat heart and cardiac myocytes. J. Pharmacol. Exp. Ther. 316, 670-678.
    • (2006) J. Pharmacol. Exp. Ther. , vol.316 , pp. 670-678
    • Bian, J.S.1    Yong, Q.C.2    Pan, T.T.3    Feng, Z.N.4    Ali, M.Y.5    Zhou, S.6    Moore, P.K.7
  • 34
    • 0000668980 scopus 로고
    • Cardiac metabolism
    • Bing, R. J. (1965). Cardiac metabolism. Physiol. Rev. 45, 171-213.
    • (1965) Physiol. Rev. , vol.45 , pp. 171-213
    • Bing, R.J.1
  • 35
    • 33747484566 scopus 로고    scopus 로고
    • Targeting dinitrophenol to mitochondria: limitations to the development of a self-limiting mitochondrial protonophore
    • Blaikie, F. H., Brown, S. E., Samuelsson, L. M., Brand, M. D., Smith, R. A., and Murphy, M. P. (2006). Targeting dinitrophenol to mitochondria: limitations to the development of a self-limiting mitochondrial protonophore. Biosci. Rep. 26, 231-243.
    • (2006) Biosci. Rep. , vol.26 , pp. 231-243
    • Blaikie, F.H.1    Brown, S.E.2    Samuelsson, L.M.3    Brand, M.D.4    Smith, R.A.5    Murphy, M.P.6
  • 37
    • 33745628317 scopus 로고    scopus 로고
    • Proapoptotic BCL-2 family members and mitochondrial dysfunction during ischemia/reperfusion injury, a study employing cardiac HL-1 cells and GFP biosensors
    • Brady, N. R., Hamacher-Brady, A., and Gottlieb, R. A. (2006a). Proapoptotic BCL-2 family members and mitochondrial dysfunction during ischemia/reperfusion injury, a study employing cardiac HL-1 cells and GFP biosensors. Biochim. Biophys. Acta 1757, 667-678.
    • (2006) Biochim. Biophys. Acta , vol.1757 , pp. 667-678
    • Brady, N.R.1    Hamacher-Brady, A.2    Gottlieb, R.A.3
  • 38
    • 33750920827 scopus 로고    scopus 로고
    • A wave of reactive oxygen species (ROS)-induced ROS release in a sea of excitable mitochondria
    • Brady, N. R., Hamacher-Brady, A., Westerhoff, H. V., and Gottlieb, R. A. (2006b). A wave of reactive oxygen species (ROS)-induced ROS release in a sea of excitable mitochondria. Antioxid. Redox Signal. 8, 1651-1665.
    • (2006) Antioxid. Redox Signal. , vol.8 , pp. 1651-1665
    • Brady, N.R.1    Hamacher-Brady, A.2    Westerhoff, H.V.3    Gottlieb, R.A.4
  • 39
    • 0014499782 scopus 로고
    • Pyruvate dehydrogenase, substrate specificity and product inhibition
    • Bremer, J. (1969). Pyruvate dehydrogenase, substrate specificity and product inhibition. Eur. J. Biochem. 8, 535-540.
    • (1969) Eur. J. Biochem. , vol.8 , pp. 535-540
    • Bremer, J.1
  • 40
    • 0015498738 scopus 로고
    • Factors controlling the rate of fatty acid-oxidation in rat liver mitochondria
    • Bremer, J., and Wojtczak, A. B. (1972). Factors controlling the rate of fatty acid-oxidation in rat liver mitochondria. Biochim. Biophys. Acta 280, 515-530.
    • (1972) Biochim. Biophys. Acta , vol.280 , pp. 515-530
    • Bremer, J.1    Wojtczak, A.B.2
  • 42
    • 0034638797 scopus 로고    scopus 로고
    • Etomoxir: a new approach to treatment of chronic heart failure
    • Bristow, M. (2000). Etomoxir: a new approach to treatment of chronic heart failure. Lancet 356, 1621-1622.
    • (2000) Lancet , vol.356 , pp. 1621-1622
    • Bristow, M.1
  • 43
    • 10344264960 scopus 로고    scopus 로고
    • Mitochondrial H+ leak and ROS generation: an odd couple
    • [Review]
    • Brookes, P. S. (2005). Mitochondrial H+ leak and ROS generation: an odd couple. Free Radic. Biol. Med. 38, 12-23. [Review].
    • (2005) Free Radic. Biol. Med. , vol.38 , pp. 12-23
    • Brookes, P.S.1
  • 45
    • 77956597409 scopus 로고    scopus 로고
    • Cardiac mitochondria and arrhythmias
    • Brown, D. A., and O'Rourke, B. (2010). Cardiac mitochondria and arrhythmias. Cardiovasc. Res. 88, 241-249.
    • (2010) Cardiovasc. Res. , vol.88 , pp. 241-249
    • Brown, D.A.1    O'Rourke, B.2
  • 47
    • 0037192787 scopus 로고    scopus 로고
    • Increased hexokinase activity, of either ectopic or endogenous origin, protects renal epithelial cells against acute oxidant-induced cell death
    • Bryson, J. M., Coy, P. E., Gottlob, K., Hay, N., and Robey, R. B. (2002). Increased hexokinase activity, of either ectopic or endogenous origin, protects renal epithelial cells against acute oxidant-induced cell death. J. Biol. Chem. 277, 11392-11400.
    • (2002) J. Biol. Chem. , vol.277 , pp. 11392-11400
    • Bryson, J.M.1    Coy, P.E.2    Gottlob, K.3    Hay, N.4    Robey, R.B.5
  • 49
    • 38349070256 scopus 로고    scopus 로고
    • Mitochondria as a target for the cardioprotective effects of nitric oxide in ischemia-reperfusion injury
    • Burwell, L. S., and Brookes, P. S. (2008). Mitochondria as a target for the cardioprotective effects of nitric oxide in ischemia-reperfusion injury. Antioxid. Redox Signal. 10, 579-599.
    • (2008) Antioxid. Redox Signal. , vol.10 , pp. 579-599
    • Burwell, L.S.1    Brookes, P.S.2
  • 50
    • 67349236041 scopus 로고    scopus 로고
    • Cardioprotection by metabolic shut-down and gradual wake-up
    • Burwell, L. S., Nadtochiy, S. M., and Brookes, P. S. (2009). Cardioprotection by metabolic shut-down and gradual wake-up. J. Mol. Cell. Cardiol. 46, 804-810.
    • (2009) J. Mol. Cell. Cardiol. , vol.46 , pp. 804-810
    • Burwell, L.S.1    Nadtochiy, S.M.2    Brookes, P.S.3
  • 51
    • 0017406503 scopus 로고
    • Production of superoxide radicals and hydrogen peroxide by NADH-ubiquinone reductase and ubiquinol-cytochrome c reductase from beef-heart mitochondria
    • Cadenas, E., Boveris, A., Ragan, C. I., and Stoppani, A. O. (1977). Production of superoxide radicals and hydrogen peroxide by NADH-ubiquinone reductase and ubiquinol-cytochrome c reductase from beef-heart mitochondria. Arch. Biochem. Biophys. 180, 248-257.
    • (1977) Arch. Biochem. Biophys. , vol.180 , pp. 248-257
    • Cadenas, E.1    Boveris, A.2    Ragan, C.I.3    Stoppani, A.O.4
  • 52
    • 0033796250 scopus 로고    scopus 로고
    • Mitochondrial free radical generation, oxidative stress, and aging
    • [Review]
    • Cadenas, E., and Davies, K. J. (2000). Mitochondrial free radical generation, oxidative stress, and aging. Free Radic. Biol. Med. 29, 222-230. [Review].
    • (2000) Free Radic. Biol. Med. , vol.29 , pp. 222-230
    • Cadenas, E.1    Davies, K.J.2
  • 53
    • 52749093466 scopus 로고    scopus 로고
    • Pyruvate dehydrogenase kinase 4 regulation by thiazolidinediones and implication in glyceroneogenesis in adipose tissue
    • Cadoudal, T., Distel, E., Durant, S., Fouque, F., Blouin, J. M., Collinet, M., Bortoli, S., Forest, C., and Benelli, C. (2008). Pyruvate dehydrogenase kinase 4: regulation by thiazolidinediones and implication in glyceroneogenesis in adipose tissue. Diabetes 57, 2272-2279.
    • (2008) Diabetes , vol.57 , pp. 2272-2279
    • Cadoudal, T.1    Distel, E.2    Durant, S.3    Fouque, F.4    Blouin, J.M.5    Collinet, M.6    Bortoli, S.7    Forest, C.8    Benelli, C.9
  • 55
    • 77950852339 scopus 로고    scopus 로고
    • Novel insights into hydrogen sulfide-mediated cytoprotection
    • Calvert, J. W., Coetzee, W. A., and Lefer, D. J. (2010). Novel insights into hydrogen sulfide-mediated cytoprotection. Antioxid. Redox Signal. 12, 1203-1217.
    • (2010) Antioxid. Redox Signal. , vol.12 , pp. 1203-1217
    • Calvert, J.W.1    Coetzee, W.A.2    Lefer, D.J.3
  • 56
    • 40949087724 scopus 로고    scopus 로고
    • Acute metformin therapy confers cardioprotection against myocardial infarction via AMPK-eNOS-mediated signaling
    • Calvert, J. W., Gundewar, S., Jha, S., Greer, J. J., Bestermann, W. H., Tian, R., and Lefer, D. J. (2008). Acute metformin therapy confers cardioprotection against myocardial infarction via AMPK-eNOS-mediated signaling. Diabetes 57, 696-705.
    • (2008) Diabetes , vol.57 , pp. 696-705
    • Calvert, J.W.1    Gundewar, S.2    Jha, S.3    Greer, J.J.4    Bestermann, W.H.5    Tian, R.6    Lefer, D.J.7
  • 58
    • 80255127175 scopus 로고    scopus 로고
    • Mitochondria as potential therapeutic targets in mitochondria-related diseases
    • Mitochondrial Structure, Function and Dysfunction, ed (Milwaukee: Nova Science)
    • Camara, A., Aldakkak, M., and Stowe, D. (2010a). "Mitochondria as potential therapeutic targets in mitochondria-related diseases," in Mitochondrial Structure, Function and Dysfunction, ed. O. L. Svensson (Milwaukee: Nova Science), 471-552.
    • (2010) O. L. Svensson , pp. 471-552
    • Camara, A.1    Aldakkak, M.2    Stowe, D.3
  • 59
    • 77954113727 scopus 로고    scopus 로고
    • Potential therapeutic benefits of strategies directed to mitochondria
    • Camara, A., Lesnefsky, E., and Stowe, D. (2010b). Potential therapeutic benefits of strategies directed to mitochondria. Antioxid. Redox Signal. 13, 279-347.
    • (2010) Antioxid. Redox Signal. , vol.13 , pp. 279-347
    • Camara, A.1    Lesnefsky, E.2    Stowe, D.3
  • 60
    • 84866458697 scopus 로고    scopus 로고
    • Cold perfusion of isolated hearts generates reactive oxygen species but reduces generation and release during and after cold ischemia
    • Camara, A., Kevin, L., Novalija, E., Varadarajan, S., and Stowe, D. (2002). Cold perfusion of isolated hearts generates reactive oxygen species but reduces generation and release during and after cold ischemia. Circulation, 106(Suppl. 2), SII-202.
    • (2002) Circulation , vol.106 , Issue.SUPPL. 2
    • Camara, A.1    Kevin, L.2    Novalija, E.3    Varadarajan, S.4    Stowe, D.5
  • 63
    • 67649243697 scopus 로고    scopus 로고
    • The cardioprotective effects elicited by p66(Shc) ablation demonstrate the crucial role of mitochondrial ROS formation in ischemia/reperfusion injury
    • Carpi, A., Menabo, R., Kaludercic, N., Pelicci, P., Di Lisa, F., and Giorgio, M. (2009). The cardioprotective effects elicited by p66(Shc) ablation demonstrate the crucial role of mitochondrial ROS formation in ischemia/reperfusion injury. Biochim. Biophys. Acta 1787, 774-780.
    • (2009) Biochim. Biophys. Acta , vol.1787 , pp. 774-780
    • Carpi, A.1    Menabo, R.2    Kaludercic, N.3    Pelicci, P.4    Di Lisa, F.5    Giorgio, M.6
  • 65
    • 0035015036 scopus 로고    scopus 로고
    • EPR studies of nitric oxide interactions of alkoxyl and peroxyl radicals in in vitro and ex vivo model systems
    • Chamulitrat, W. (2001). EPR studies of nitric oxide interactions of alkoxyl and peroxyl radicals in in vitro and ex vivo model systems. Antioxid. Redox Signal. 3, 177-187.
    • (2001) Antioxid. Redox Signal. , vol.3 , pp. 177-187
    • Chamulitrat, W.1
  • 66
    • 77954741221 scopus 로고    scopus 로고
    • Mitochondria and heart failure: new insights into an energetic problem
    • Chen, L., and Knowlton, A. A. (2010). Mitochondria and heart failure: new insights into an energetic problem. Minerva Cardioangiol. 58, 213-229.
    • (2010) Minerva Cardioangiol , vol.58 , pp. 213-229
    • Chen, L.1    Knowlton, A.A.2
  • 67
    • 33846335174 scopus 로고    scopus 로고
    • Modulation of electron transport protects cardiac mitochondria and decreases myocardial injury during ischemia and reperfusion
    • [Review]
    • Chen, Q., Camara, A. K., Stowe, D. F., Hoppel, C. L., and Lesnefsky, E. J. (2007). Modulation of electron transport protects cardiac mitochondria and decreases myocardial injury during ischemia and reperfusion. Am. J. Physiol. Cell Physiol. 292, C137-C147. [Review].
    • (2007) Am. J. Physiol. Cell Physiol. , vol.292
    • Chen, Q.1    Camara, A.K.2    Stowe, D.F.3    Hoppel, C.L.4    Lesnefsky, E.J.5
  • 68
    • 33751177799 scopus 로고    scopus 로고
    • Reversible blockade of electron transport during ischemia protects mitochondria and decreases myocardial injury following reperfusion
    • Chen, Q., Moghaddas, S., Hoppel, C. L., and Lesnefsky, E. J. (2006). Reversible blockade of electron transport during ischemia protects mitochondria and decreases myocardial injury following reperfusion. J. Pharmacol. Exp. Ther. 319, 1405-1412.
    • (2006) J. Pharmacol. Exp. Ther. , vol.319 , pp. 1405-1412
    • Chen, Q.1    Moghaddas, S.2    Hoppel, C.L.3    Lesnefsky, E.J.4
  • 69
    • 39549102405 scopus 로고    scopus 로고
    • Ischemic defects in the electron transport chain increase the production of reactive oxygen species from isolated rat heart mitochondria
    • Chen, Q., Moghaddas, S., Hoppel, C. L., and Lesnefsky, E. J. (2008). Ischemic defects in the electron transport chain increase the production of reactive oxygen species from isolated rat heart mitochondria. Am. J. Physiol. Cell Physiol. 294, C460-C466.
    • (2008) Am. J. Physiol. Cell Physiol. , vol.294
    • Chen, Q.1    Moghaddas, S.2    Hoppel, C.L.3    Lesnefsky, E.J.4
  • 70
    • 0141815741 scopus 로고    scopus 로고
    • Production of reactive oxygen species by mitochondria: central role of complex III
    • Chen, Q., Vazquez, E. J., Moghaddas, S., Hoppel, C. L., and Lesnefsky, E. J. (2003). Production of reactive oxygen species by mitochondria: central role of complex III. J. Biol. Chem. 278, 36027-36031.
    • (2003) J. Biol. Chem. , vol.278 , pp. 36027-36031
    • Chen, Q.1    Vazquez, E.J.2    Moghaddas, S.3    Hoppel, C.L.4    Lesnefsky, E.J.5
  • 71
    • 77954387143 scopus 로고    scopus 로고
    • Isolating the segment of the mitochondrial electron transport chain responsible for mitochondrial damage during cardiac ischemia
    • Chen, Q., Yin, G., Stewart, S., Hu, Y., and Lesnefsky, E. J. (2010). Isolating the segment of the mitochondrial electron transport chain responsible for mitochondrial damage during cardiac ischemia. Biochem. Biophys. Res. Commun. 397, 656-660.
    • (2010) Biochem. Biophys. Res. Commun. , vol.397 , pp. 656-660
    • Chen, Q.1    Yin, G.2    Stewart, S.3    Hu, Y.4    Lesnefsky, E.J.5
  • 72
    • 65449119234 scopus 로고    scopus 로고
    • Role of mitochondria-associated hexokinase II in cancer cell death induced by 3-bromopyruvate
    • Chen, Z., Zhang, H., Lu, W., and Huang, P. (2009). Role of mitochondria-associated hexokinase II in cancer cell death induced by 3-bromopyruvate. Biochim. Biophys. Acta 1787, 553-560.
    • (2009) Biochim. Biophys. Acta , vol.1787 , pp. 553-560
    • Chen, Z.1    Zhang, H.2    Lu, W.3    Huang, P.4
  • 73
    • 9144262378 scopus 로고    scopus 로고
    • Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy
    • Cheng, L., Ding, G., Qin, Q., Huang, Y., Lewis, W., He, N., Evans, R. M., Schneider, M. D., Brako, F. A., Xiao, Y., Chen, Y. E., and Yang, Q. (2004). Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy. Nat. Med. 10, 1245-1250.
    • (2004) Nat. Med. , vol.10 , pp. 1245-1250
    • Cheng, L.1    Ding, G.2    Qin, Q.3    Huang, Y.4    Lewis, W.5    He, N.6    Evans, R.M.7    Schneider, M.D.8    Brako, F.A.9    Xiao, Y.10    Chen, Y.E.11    Yang, Q.12
  • 74
    • 78651347754 scopus 로고    scopus 로고
    • Biphasic effect of nitric oxide on the cardiac voltage-dependent anion channel
    • Cheng, Q., Sedlic, F., Pravdic, D., Bosnjak, Z. J., and Kwok, W. M. (2011). Biphasic effect of nitric oxide on the cardiac voltage-dependent anion channel. FEBS Lett. 585, 328-334.
    • (2011) FEBS Lett , vol.585 , pp. 328-334
    • Cheng, Q.1    Sedlic, F.2    Pravdic, D.3    Bosnjak, Z.J.4    Kwok, W.M.5
  • 75
    • 33947495568 scopus 로고    scopus 로고
    • A novel cell-permeable antioxidant peptide, SS31, attenuates ischemic brain injury by down-regulating CD36
    • Cho, S., Szeto, H. H., Kim, E., Kim, H., Tolhurst, A. T., and Pinto, J. T. (2007). A novel cell-permeable antioxidant peptide, SS31, attenuates ischemic brain injury by down-regulating CD36. J. Biol. Chem. 282, 4634-4642.
    • (2007) J. Biol. Chem. , vol.282 , pp. 4634-4642
    • Cho, S.1    Szeto, H.H.2    Kim, E.3    Kim, H.4    Tolhurst, A.T.5    Pinto, J.T.6
  • 76
    • 0032755436 scopus 로고    scopus 로고
    • Monoamine oxidase and mitochondrial respiration
    • Cohen, G., and Kesler, N. (1999a). Monoamine oxidase and mitochondrial respiration. J. Neurochem. 73, 2310-2315.
    • (1999) J. Neurochem. , vol.73 , pp. 2310-2315
    • Cohen, G.1    Kesler, N.2
  • 77
    • 0033387533 scopus 로고    scopus 로고
    • Monoamine oxidase inhibits mitochondrial respiration
    • Cohen, G., and Kesler, N. (1999b). Monoamine oxidase inhibits mitochondrial respiration. Ann. N. Y. Acad. Sci. 893, 273-278.
    • (1999) Ann. N. Y. Acad. Sci. , vol.893 , pp. 273-278
    • Cohen, G.1    Kesler, N.2
  • 78
    • 0037007227 scopus 로고    scopus 로고
    • Mitochondria are morphologically and functionally heterogeneous within cells
    • Collins, T. J., Berridge, M. J., Lipp, P., and Bootman, M. D. (2002). Mitochondria are morphologically and functionally heterogeneous within cells. EMBO J. 21, 1616-1627.
    • (2002) EMBO J , vol.21 , pp. 1616-1627
    • Collins, T.J.1    Berridge, M.J.2    Lipp, P.3    Bootman, M.D.4
  • 79
    • 57049151773 scopus 로고    scopus 로고
    • The inhibition of mitochondrial cytochrome oxidase by the gases carbon monoxide, nitric oxide, hydrogen cyanide and hydrogen sulfide: chemical mechanism and physiological significance
    • Cooper, C. E., and Brown, G. C. (2008). The inhibition of mitochondrial cytochrome oxidase by the gases carbon monoxide, nitric oxide, hydrogen cyanide and hydrogen sulfide: chemical mechanism and physiological significance. J. Bioenerg. Biomembr. 40, 533-539.
    • (2008) J. Bioenerg. Biomembr. , vol.40 , pp. 533-539
    • Cooper, C.E.1    Brown, G.C.2
  • 81
    • 66149107066 scopus 로고    scopus 로고
    • Control and regulation of mitochondrial energetics in an integrated model of cardiomyocyte function
    • Cortassa, S., O'Rourke, B., Winslow, R. L., and Aon, M. A. (2009). Control and regulation of mitochondrial energetics in an integrated model of cardiomyocyte function. Biophys. J. 96, 2466-2478.
    • (2009) Biophys. J. , vol.96 , pp. 2466-2478
    • Cortassa, S.1    O'Rourke, B.2    Winslow, R.L.3    Aon, M.A.4
  • 83
    • 0023391047 scopus 로고
    • 2+-dependent pore activated by oxidative stress in heart mitochondria
    • 2+-dependent pore activated by oxidative stress in heart mitochondria. Biochem. J. 245, 915-918.
    • (1987) Biochem. J. , vol.245 , pp. 915-918
    • Crompton, M.1    Costi, A.2    Hayat, L.3
  • 86
    • 0035163552 scopus 로고    scopus 로고
    • Calcium signal transmission between ryanodine receptors and mitochondria in cardiac muscle
    • Csordas, G., Thomas, A. P., and Hajnoczky, G. (2001). Calcium signal transmission between ryanodine receptors and mitochondria in cardiac muscle. Trends Cardiovasc. Med. 11, 269-275.
    • (2001) Trends Cardiovasc. Med. , vol.11 , pp. 269-275
    • Csordas, G.1    Thomas, A.P.2    Hajnoczky, G.3
  • 87
    • 0028215199 scopus 로고
    • Lipopolysaccharide-neutralizing antibody reduces hepatocyte injury from acute hepatotoxin administration
    • Czaja, M. J., Xu, J., Ju, Y., Alt, E., and Schmiedeberg, P. (1994). Lipopolysaccharide-neutralizing antibody reduces hepatocyte injury from acute hepatotoxin administration. Hepatology 19, 1282-1289.
    • (1994) Hepatology , vol.19 , pp. 1282-1289
    • Czaja, M.J.1    Xu, J.2    Ju, Y.3    Alt, E.4    Schmiedeberg, P.5
  • 88
    • 0024602685 scopus 로고
    • An ultrastructural study of the hypertrophied human papillary muscle cell with special emphasis on specific staining patterns, mitochondrial projections and association between mitochondria and SR. Virchows Arch. A
    • Dalen, H. (1989). An ultrastructural study of the hypertrophied human papillary muscle cell with special emphasis on specific staining patterns, mitochondrial projections and association between mitochondria and SR. Virchows Arch. A, Pathol. Anat. Histopathol. 414, 187-198.
    • (1989) Pathol. Anat. Histopathol. , vol.414 , pp. 187-198
    • Dalen, H.1
  • 89
    • 77955684288 scopus 로고    scopus 로고
    • Resveratrol and red wine, healthy heart and longevity
    • Das, D. K., Mukherjee, S., and Ray, D. (2010). Resveratrol and red wine, healthy heart and longevity. Heart Fail. Rev. 15, 467-477.
    • (2010) Heart Fail. Rev. , vol.15 , pp. 467-477
    • Das, D.K.1    Mukherjee, S.2    Ray, D.3
  • 90
    • 55449092939 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3 inhibition slows mitochondrial adenine nucleotide transport and regulates voltage-dependent anion channel phosphorylation
    • Das, S., Wong, R., Rajapakse, N., Murphy, E., and Steenbergen, C. (2008). Glycogen synthase kinase 3 inhibition slows mitochondrial adenine nucleotide transport and regulates voltage-dependent anion channel phosphorylation. Circ. Res. 103, 983-991.
    • (2008) Circ. Res. , vol.103 , pp. 983-991
    • Das, S.1    Wong, R.2    Rajapakse, N.3    Murphy, E.4    Steenbergen, C.5
  • 91
    • 34247598856 scopus 로고    scopus 로고
    • Endothelial mitochondria: contributing to vascular function and disease
    • Davidson, S. M., and Duchen, M. R. (2007). Endothelial mitochondria: contributing to vascular function and disease. Circ. Res. 100, 1128-1141.
    • (2007) Circ. Res. , vol.100 , pp. 1128-1141
    • Davidson, S.M.1    Duchen, M.R.2
  • 93
    • 33646060099 scopus 로고    scopus 로고
    • Mitochondria and ischemia-reperfusion injury of the heart: fixing a hole
    • Di Lisa, F., and Bernardi, P. (2006). Mitochondria and ischemia-reperfusion injury of the heart: fixing a hole. Cardiovasc. Res. 70, 191-199.
    • (2006) Cardiovasc. Res. , vol.70 , pp. 191-199
    • Di Lisa, F.1    Bernardi, P.2
  • 94
    • 62249115660 scopus 로고    scopus 로고
    • Mitochondrial pathways for ROS formation and myocardial injury: the relevance of p66(Shc) and monoamine oxidase
    • Di Lisa, F., Kaludercic, N., Carpi, A., Menabo, R., and Giorgio, M. (2009). Mitochondrial pathways for ROS formation and myocardial injury: the relevance of p66(Shc) and monoamine oxidase. Basic Res. Cardiol. 104, 131-139.
    • (2009) Basic Res. Cardiol. , vol.104 , pp. 131-139
    • Di Lisa, F.1    Kaludercic, N.2    Carpi, A.3    Menabo, R.4    Giorgio, M.5
  • 95
  • 97
    • 0036773760 scopus 로고    scopus 로고
    • Prevention of apoptosis by deferoxamine during 4 hours of cold cardioplegia and reperfusion: in vitro study of isolated working rat heart model
    • Dobsak, P., Siegelova, J., Wolf, J. E., Rochette, L., Eicher, J. C., Vasku, J., Kuchtickova, S., and Horky, M. (2002). Prevention of apoptosis by deferoxamine during 4 hours of cold cardioplegia and reperfusion: in vitro study of isolated working rat heart model. Pathophysiology 9, 27.
    • (2002) Pathophysiology , vol.9 , pp. 27
    • Dobsak, P.1    Siegelova, J.2    Wolf, J.E.3    Rochette, L.4    Eicher, J.C.5    Vasku, J.6    Kuchtickova, S.7    Horky, M.8
  • 98
    • 0038381490 scopus 로고    scopus 로고
    • Inhibition of the mitochondrial permeability transition by creatine kinase substrates Requirement for microcompartmentation
    • Dolder, M., Walzel, B., Speer, O., Schlattner, U., and Wallimann, T. (2003). Inhibition of the mitochondrial permeability transition by creatine kinase substrates. Requirement for microcompartmentation. J. Biol. Chem. 278, 17760-17766.
    • (2003) J. Biol. Chem. , vol.278 , pp. 17760-17766
    • Dolder, M.1    Walzel, B.2    Speer, O.3    Schlattner, U.4    Wallimann, T.5
  • 99
    • 0142010897 scopus 로고    scopus 로고
    • A peptide trivalent arsenical inhibits tumor angiogenesis by perturbing mitochondrial function in angiogenic endothelial cells
    • Don, A. S., Kisker, O., Dilda, P., Donoghue, N., Zhao, X., Decollogne, S., Creighton, B., Flynn, E., Folkman, J., and Hogg, P. J. (2003). A peptide trivalent arsenical inhibits tumor angiogenesis by perturbing mitochondrial function in angiogenic endothelial cells. Cancer Cell 3, 497-509.
    • (2003) Cancer Cell , vol.3 , pp. 497-509
    • Don, A.S.1    Kisker, O.2    Dilda, P.3    Donoghue, N.4    Zhao, X.5    Decollogne, S.6    Creighton, B.7    Flynn, E.8    Folkman, J.9    Hogg, P.J.10
  • 100
    • 77957284223 scopus 로고    scopus 로고
    • Two close, too close: sarcoplasmic reticulum-mitochondrial crosstalk and cardiomyocyte fate
    • Dorn, G. W. II, and Scorrano, L. (2010). Two close, too close: sarcoplasmic reticulum-mitochondrial crosstalk and cardiomyocyte fate. Circ. Res. 107, 689-699.
    • (2010) Circ. Res. , vol.107 , pp. 689-699
    • Dorn, G.W.1    Scorrano II, L.2
  • 101
    • 0030853574 scopus 로고    scopus 로고
    • Adenine nucleotide translocator in dilated cardiomyopathy: pathophysiological alterations in expression and function
    • Dorner, A., Schulze, K., Rauch, U., and Schultheiss, H. P. (1997). Adenine nucleotide translocator in dilated cardiomyopathy: pathophysiological alterations in expression and function. Mol. Cell. Biochem. 174, 261-269.
    • (1997) Mol. Cell. Biochem. , vol.174 , pp. 261-269
    • Dorner, A.1    Schulze, K.2    Rauch, U.3    Schultheiss, H.P.4
  • 102
    • 41949104144 scopus 로고    scopus 로고
    • Molecular mechanisms of angiotensin II-mediated mitochondrial dysfunction: linking mitochondrial oxidative damage and vascular endothelial dysfunction
    • Doughan, A. K., Harrison, D. G., and Dikalov, S. I. (2008). Molecular mechanisms of angiotensin II-mediated mitochondrial dysfunction: linking mitochondrial oxidative damage and vascular endothelial dysfunction. Circ. Res. 102, 488-496.
    • (2008) Circ. Res. , vol.102 , pp. 488-496
    • Doughan, A.K.1    Harrison, D.G.2    Dikalov, S.I.3
  • 104
    • 4043086952 scopus 로고    scopus 로고
    • Mitochondria in health and disease: perspectives on a new mitochondrial biology
    • Duchen, M. R. (2004). Mitochondria in health and disease: perspectives on a new mitochondrial biology. Mol. Aspects Med. 25, 365-451.
    • (2004) Mol. Aspects Med. , vol.25 , pp. 365-451
    • Duchen, M.R.1
  • 105
    • 33644641668 scopus 로고    scopus 로고
    • Estrogen and mitochondria: a new paradigm for vascular protection?
    • Duckles, S. P., Krause, D. N., Stirone, C., and Procaccio, V. (2006). Estrogen and mitochondria: a new paradigm for vascular protection? Mol. Interv. 6, 26-35.
    • (2006) Mol Interv , vol.6 , pp. 26-35
    • Duckles, S.P.1    Krause, D.N.2    Stirone, C.3    Procaccio, V.4
  • 107
    • 57049142195 scopus 로고    scopus 로고
    • Cardiac hypertrophy is associated with altered thioredoxin and ASK-1 signaling in a mouse model of menopause
    • Ebrahimian, T., Sairam, M. R., Schiffrin, E. L., and Touyz, R. M. (2008). Cardiac hypertrophy is associated with altered thioredoxin and ASK-1 signaling in a mouse model of menopause. Am. J. Physiol. Heart Circ. Physiol. 295, H1481-H1488.
    • (2008) Am. J. Physiol. Heart Circ. Physiol. , vol.295
    • Ebrahimian, T.1    Sairam, M.R.2    Schiffrin, E.L.3    Touyz, R.M.4
  • 108
    • 41349093140 scopus 로고    scopus 로고
    • Thioredoxin in vascular biology: role in hypertension
    • Ebrahimian, T., and Touyz, R. M. (2008). Thioredoxin in vascular biology: role in hypertension. Antioxid. Redox Signal. 10, 1127-1136.
    • (2008) Antioxid. Redox Signal. , vol.10 , pp. 1127-1136
    • Ebrahimian, T.1    Touyz, R.M.2
  • 111
    • 0242274919 scopus 로고
    • Effectors of rat-heart hexokinases and the control of rates of glucose phosphorylation in the perfused rat heart
    • England, P. J., and Randle, P. J. (1967). Effectors of rat-heart hexokinases and the control of rates of glucose phosphorylation in the perfused rat heart. Biochem. J. 105, 907-920.
    • (1967) Biochem. J. , vol.105 , pp. 907-920
    • England, P.J.1    Randle, P.J.2
  • 113
    • 0026802334 scopus 로고
    • Metabolic control analysis: a survey of its theoretical and experimental development
    • Fell, D. A. (1992). Metabolic control analysis: a survey of its theoretical and experimental development. Biochem. J. 286(Pt 2), 313-330.
    • (1992) Biochem. J. , vol.286 , Issue.PART 2 , pp. 313-330
    • Fell, D.A.1
  • 114
    • 0037293568 scopus 로고    scopus 로고
    • Nitric oxide, superoxide, and peroxynitrite in myocardial ischaemia-reperfusion injury and preconditioning
    • Ferdinandy, P., and Schulz, R. (2003). Nitric oxide, superoxide, and peroxynitrite in myocardial ischaemia-reperfusion injury and preconditioning. Br. J. Pharmacol. 138, 532-543.
    • (2003) Br. J. Pharmacol. , vol.138 , pp. 532-543
    • Ferdinandy, P.1    Schulz, R.2
  • 117
    • 33847349283 scopus 로고    scopus 로고
    • Reactive oxygen species: a breath of life or death?
    • [Review]
    • Fruehauf, J. P., and Meyskens, F. L. Jr. (2007). Reactive oxygen species: a breath of life or death? Clin. Cancer Res. 13, 789-794. [Review].
    • (2007) Clin Cancer Res , vol.13 , pp. 789-794
    • Fruehauf, J.P.1    Meyskens Jr., F.L.2
  • 120
    • 49149087268 scopus 로고    scopus 로고
    • Disruption of the hexokinase-VDAC complex for tumor therapy
    • Galluzzi, L., Kepp, O., Tajeddine, N., and Kroemer, G. (2008). Disruption of the hexokinase-VDAC complex for tumor therapy. Oncogene 27, 4633-4635.
    • (2008) Oncogene , vol.27 , pp. 4633-4635
    • Galluzzi, L.1    Kepp, O.2    Tajeddine, N.3    Kroemer, G.4
  • 121
    • 0017121942 scopus 로고
    • Oxygen-induced enzyme release after irreversible myocardial injury Effects of cyanide in perfused rat hearts
    • Ganote, C. E., Worstell, J., and Kaltenbach, J. P. (1976). Oxygen-induced enzyme release after irreversible myocardial injury. Effects of cyanide in perfused rat hearts. Am. J. Pathol. 84, 327-350.
    • (1976) Am. J. Pathol. , vol.84 , pp. 327-350
    • Ganote, C.E.1    Worstell, J.2    Kaltenbach, J.P.3
  • 122
    • 0001134693 scopus 로고
    • Citrate as an intermediary in the inhibition of phosphofructokinase in rat heart muscle by fatty acids, ketone bodies, pyruvate, diabetes, and starvation
    • Garland, P. B., Randle, P. J., and Newsholme, E. A. (1963). Citrate as an intermediary in the inhibition of phosphofructokinase in rat heart muscle by fatty acids, ketone bodies, pyruvate, diabetes, and starvation. Nature 200, 169-170.
    • (1963) Nature , vol.200 , pp. 169-170
    • Garland, P.B.1    Randle, P.J.2    Newsholme, E.A.3
  • 123
    • 0142042974 scopus 로고    scopus 로고
    • Mitochondrial potassium transport: the role of the mitochondrial ATP-sensitive K+ channel in cardiac function and cardioprotection
    • Garlid, K. D., Dos Santos, P., Xie, Z. J., Costa, A. D., and Paucek, P. (2003). Mitochondrial potassium transport: the role of the mitochondrial ATP-sensitive K+ channel in cardiac function and cardioprotection. Biochim. Biophys. Acta 1606, 1-21.
    • (2003) Biochim. Biophys. Acta , vol.1606 , pp. 1-21
    • Garlid, K.D.1    Dos Santos, P.2    Xie, Z.J.3    Costa, A.D.4    Paucek, P.5
  • 124
    • 0141634243 scopus 로고    scopus 로고
    • Depressed mitochondrial transcription factors and oxidative capacity in rat failing cardiac and skeletal muscles
    • Garnier, A., Fortin, D., Delomenie, C., Momken, I., Veksler, V., and Ventura-Clapier, R. (2003). Depressed mitochondrial transcription factors and oxidative capacity in rat failing cardiac and skeletal muscles. J. Physiol. 551(Pt 2), 491-501.
    • (2003) J. Physiol. , vol.551 , Issue.PART 2 , pp. 491-501
    • Garnier, A.1    Fortin, D.2    Delomenie, C.3    Momken, I.4    Veksler, V.5    Ventura-Clapier, R.6
  • 125
    • 53449085187 scopus 로고    scopus 로고
    • The functional nitrite reductase activity of the heme-globins
    • Gladwin, M. T., and Kim-Shapiro, D. B. (2008). The functional nitrite reductase activity of the heme-globins. Blood 112, 2636-2647.
    • (2008) Blood , vol.112 , pp. 2636-2647
    • Gladwin, M.T.1    Kim-Shapiro, D.B.2
  • 127
    • 67349280415 scopus 로고    scopus 로고
    • Inhibition of mitochondrial permeability transition pore opening: translation to patients
    • Gomez, L., Li, B., Mewton, N., Sanchez, I., Piot, C., Elbaz, M., and Ovize, M. (2009). Inhibition of mitochondrial permeability transition pore opening: translation to patients. Cardiovasc. Res. 83, 226-233.
    • (2009) Cardiovasc. Res. , vol.83 , pp. 226-233
    • Gomez, L.1    Li, B.2    Mewton, N.3    Sanchez, I.4    Piot, C.5    Elbaz, M.6    Ovize, M.7
  • 129
    • 0029069277 scopus 로고
    • Reduction of ferrylmyoglobin and ferrylhemoglobin by nitric oxide: a protective mechanism against ferryl hemoprotein-induced oxidations
    • Gorbunov, N. V., Osipov, A. N., Day, B. W., Zayas-Rivera, B., Kagan, V. E., and Elsayed, N. M. (1995). Reduction of ferrylmyoglobin and ferrylhemoglobin by nitric oxide: a protective mechanism against ferryl hemoprotein-induced oxidations. Biochemistry 34, 6689-6699.
    • (1995) Biochemistry , vol.34 , pp. 6689-6699
    • Gorbunov, N.V.1    Osipov, A.N.2    Day, B.W.3    Zayas-Rivera, B.4    Kagan, V.E.5    Elsayed, N.M.6
  • 130
    • 0030998378 scopus 로고    scopus 로고
    • Nitric oxide prevents oxidative damage produced by tert-butyl hydroperoxide in erythroleukemia cells via nitrosylation of heme and non-heme iron Electron paramagnetic resonance evidence
    • Gorbunov, N. V., Yalowich, J. C., Gaddam, A., Thampatty, P., Ritov, V. B., Kisin, E. R., Elsayed, N. M., and Kagan, V. E. (1997). Nitric oxide prevents oxidative damage produced by tert-butyl hydroperoxide in erythroleukemia cells via nitrosylation of heme and non-heme iron. Electron paramagnetic resonance evidence. J. Biol. Chem. 272, 12328-12341.
    • (1997) J. Biol. Chem. , vol.272 , pp. 12328-12341
    • Gorbunov, N.V.1    Yalowich, J.C.2    Gaddam, A.3    Thampatty, P.4    Ritov, V.B.5    Kisin, E.R.6    Elsayed, N.M.7    Kagan, V.E.8
  • 131
    • 63649159307 scopus 로고    scopus 로고
    • p66Shc links alpha1-adrenergic receptors to a reactive oxygen species-dependent AKT-FOXO3A phosphorylation pathway in cardiomyocytes
    • Guo, J., Gertsberg, Z., Ozgen, N., and Steinberg, S. F. (2009). p66Shc links alpha1-adrenergic receptors to a reactive oxygen species-dependent AKT-FOXO3A phosphorylation pathway in cardiomyocytes. Circ. Res. 104, 660-669.
    • (2009) Circ. Res. , vol.104 , pp. 660-669
    • Guo, J.1    Gertsberg, Z.2    Ozgen, N.3    Steinberg, S.F.4
  • 132
    • 78049481928 scopus 로고    scopus 로고
    • Deletion of mitochondrial uncoupling protein-2 increases ischemic brain damage after transient focal ischemia by altering gene expression patterns and enhancing inflammatory cytokines
    • Haines, B. A., Mehta, S. L., Pratt, S. M., Warden, C. H., and Li, P. A. (2010). Deletion of mitochondrial uncoupling protein-2 increases ischemic brain damage after transient focal ischemia by altering gene expression patterns and enhancing inflammatory cytokines. J. Cereb. Blood Flow Metab. 30, 1825-1833.
    • (2010) J. Cereb. Blood Flow Metab. , vol.30 , pp. 1825-1833
    • Haines, B.A.1    Mehta, S.L.2    Pratt, S.M.3    Warden, C.H.4    Li, P.A.5
  • 133
    • 78049244488 scopus 로고    scopus 로고
    • Calcium signalling: fishing out molecules of mitochondrial calcium transport
    • Hajnoczky, G., and Csordas, G. (2010). Calcium signalling: fishing out molecules of mitochondrial calcium transport. Curr. Biol. 20, R888-R891.
    • (2010) Curr. Biol. , vol.20
    • Hajnoczky, G.1    Csordas, G.2
  • 134
    • 77955955395 scopus 로고    scopus 로고
    • A pore way to die: the role of mitochondria in reperfusion injury and cardioprotection
    • Halestrap, A. P. (2010). A pore way to die: the role of mitochondria in reperfusion injury and cardioprotection. Biochem. Soc. Trans. 38, 841-860.
    • (2010) Biochem. Soc. Trans. , vol.38 , pp. 841-860
    • Halestrap, A.P.1
  • 135
    • 1142273368 scopus 로고    scopus 로고
    • Mitochondrial permeability transition pore opening during myocardial reperfusion - a target for cardioprotection
    • Halestrap, A. P., Clarke, S. J., and Javadov, S. A. (2004). Mitochondrial permeability transition pore opening during myocardial reperfusion - a target for cardioprotection. Cardiovasc. Res. 61, 372-385.
    • (2004) Cardiovasc. Res. , vol.61 , pp. 372-385
    • Halestrap, A.P.1    Clarke, S.J.2    Javadov, S.A.3
  • 136
    • 34547130863 scopus 로고    scopus 로고
    • The role of mitochondria in protection of the heart by preconditioning
    • Halestrap, A. P., Clarke, S. J., and Khaliulin, I. (2007). The role of mitochondria in protection of the heart by preconditioning. Biochim. Biophys. Acta 1767, 1007-1031.
    • (2007) Biochim. Biophys. Acta , vol.1767 , pp. 1007-1031
    • Halestrap, A.P.1    Clarke, S.J.2    Khaliulin, I.3
  • 137
    • 0028293072 scopus 로고
    • Light-induced structural changes in cytochrome c oxidase: implication for the mechanism of electron and proton gating
    • Hallen, S., and Brzezinski, P. (1994). Light-induced structural changes in cytochrome c oxidase: implication for the mechanism of electron and proton gating. Biochim. Biophys. Acta 1184, 207-218.
    • (1994) Biochim. Biophys. Acta , vol.1184 , pp. 207-218
    • Hallen, S.1    Brzezinski, P.2
  • 138
    • 0027518651 scopus 로고
    • Light-induced structural changes in cytochrome c oxidase Measurements of electrogenic events and absorbance changes
    • Hallen, S., Oliveberg, M., and Brzezinski, P. (1993). Light-induced structural changes in cytochrome c oxidase. Measurements of electrogenic events and absorbance changes. FEBS Lett. 318, 134-138.
    • (1993) FEBS Lett , vol.318 , pp. 134-138
    • Hallen, S.1    Oliveberg, M.2    Brzezinski, P.3
  • 139
    • 20644462354 scopus 로고    scopus 로고
    • KATP channels and preconditioning: a re-examination of the role of mitochondrial KATP channels and an overview of alternative mechanisms
    • Hanley, P. J., and Daut, J. (2005). KATP channels and preconditioning: a re-examination of the role of mitochondrial KATP channels and an overview of alternative mechanisms. J. Mol. Cell. Cardiol. 39, 17-50.
    • (2005) J. Mol. Cell. Cardiol. , vol.39 , pp. 17-50
    • Hanley, P.J.1    Daut, J.2
  • 140
    • 0037337086 scopus 로고    scopus 로고
    • Beta-oxidation of 5-hydroxydecanoate, a putative blocker of mitochondrial ATP-sensitive potassium channels
    • Hanley, P. J., Gopalan, K. V., Lareau, R. A., Srivastava, D. K., von Meltzer, M., and Daut, J. (2003). Beta-oxidation of 5-hydroxydecanoate, a putative blocker of mitochondrial ATP-sensitive potassium channels. J. Physiol. 547(Pt 2), 387-393.
    • (2003) J. Physiol. , vol.547 , Issue.PART 2 , pp. 387-393
    • Hanley, P.J.1    Gopalan, K.V.2    Lareau, R.A.3    Srivastava, D.K.4    von Meltzer, M.5    Daut, J.6
  • 141
    • 0036686036 scopus 로고    scopus 로고
    • KATP channel-independent targets of diazoxide and 5-hydroxydecanoate in the heart
    • Hanley, P. J., Mickel, M., Loffler, M., Brandt, U., and Daut, J. (2002). KATP channel-independent targets of diazoxide and 5-hydroxydecanoate in the heart. J. Physiol. 542(Pt 3), 735-741.
    • (2002) J. Physiol. , vol.542 , Issue.PART 3 , pp. 735-741
    • Hanley, P.J.1    Mickel, M.2    Loffler, M.3    Brandt, U.4    Daut, J.5
  • 142
    • 0029051291 scopus 로고
    • Routes and regulation of NADPH pro-duction in steroidogenic mitochondria
    • Hanukoglu, I., and Rapoport, R. (1995). Routes and regulation of NADPH pro-duction in steroidogenic mitochondria. Endocr. Res. 21, 231-241.
    • (1995) Endocr. Res. , vol.21 , pp. 231-241
    • Hanukoglu, I.1    Rapoport, R.2
  • 143
    • 68049083727 scopus 로고    scopus 로고
    • Alterations of mitochondrial function in sepsis and critical illness
    • Harrois, A., Huet, O., and Duranteau, J. (2009). Alterations of mitochondrial function in sepsis and critical illness. Curr. Opin. Anaesthesiol. 22, 143-149.
    • (2009) Curr. Opin. Anaesthesiol. , vol.22 , pp. 143-149
    • Harrois, A.1    Huet, O.2    Duranteau, J.3
  • 144
    • 0027960215 scopus 로고
    • Superoxide and peroxynitrite inactivate aconitases, but nitric oxide does not
    • Hausladen, A., and Fridovich, I. (1994). Superoxide and peroxynitrite inactivate aconitases, but nitric oxide does not. J. Biol. Chem. 269, 29405-29408.
    • (1994) J. Biol. Chem. , vol.269 , pp. 29405-29408
    • Hausladen, A.1    Fridovich, I.2
  • 147
    • 0015989446 scopus 로고
    • A linear steady-state treatment of enzymatic chains. General properties, control and effector strength
    • Heinrich, R., and Rapoport, T. A. (1974). A linear steady-state treatment of enzymatic chains. General properties, control and effector strength. Eur. J. Biochem. 42, 89-95.
    • (1974) Eur. J. Biochem. , vol.42 , pp. 89-95
    • Heinrich, R.1    Rapoport, T.A.2
  • 149
    • 23744471140 scopus 로고    scopus 로고
    • Mitochondria and ischemia/ reperfusion injury
    • Honda, H. M., Korge, P., and Weiss, J. N. (2005). Mitochondria and ischemia/ reperfusion injury. Ann. N. Y. Acad. Sci. 1047, 248-258.
    • (2005) Ann. N. Y. Acad. Sci. , vol.1047 , pp. 248-258
    • Honda, H.M.1    Korge, P.2    Weiss, J.N.3
  • 150
    • 77952672524 scopus 로고    scopus 로고
    • Mitochondrial calcium channels
    • Hoppe, U. C. (2010). Mitochondrial calcium channels. FEBS Lett. 584, 1975-1981.
    • (2010) FEBS Lett , vol.584 , pp. 1975-1981
    • Hoppe, U.C.1
  • 152
    • 0035896205 scopus 로고    scopus 로고
    • Mitochondrial DNA damage and dysfunction associated with oxidative stress in failing hearts after myocardial infarction
    • Ide, T., Tsutsui, H., Hayashidani, S., Kang, D., Suematsu, N., Nakamura, K., Utsumi, H., Hamasaki, N., and Takeshita, A. (2001). Mitochondrial DNA damage and dysfunction associated with oxidative stress in failing hearts after myocardial infarction. Circ. Res. 88, 529-535.
    • (2001) Circ. Res. , vol.88 , pp. 529-535
    • Ide, T.1    Tsutsui, H.2    Hayashidani, S.3    Kang, D.4    Suematsu, N.5    Nakamura, K.6    Utsumi, H.7    Hamasaki, N.8    Takeshita, A.9
  • 153
    • 20444392739 scopus 로고    scopus 로고
    • Interactions of mitochondria-targeted and untargeted ubiquinones with the mitochondrial respiratory chain and reactive oxygen species Implications for the use of exogenous ubiquinones as therapies and experimental tools
    • James, A. M., Cocheme, H. M., Smith, R. A., and Murphy, M. P. (2005). Interactions of mitochondria-targeted and untargeted ubiquinones with the mitochondrial respiratory chain and reactive oxygen species. Implications for the use of exogenous ubiquinones as therapies and experimental tools. J. Biol. Chem. 280, 21295-21312.
    • (2005) J. Biol. Chem. , vol.280 , pp. 21295-21312
    • James, A.M.1    Cocheme, H.M.2    Smith, R.A.3    Murphy, M.P.4
  • 154
    • 38849122011 scopus 로고    scopus 로고
    • NHE-1 inhibition-induced cardioprotection against ischaemia/reperfusion is associated with attenuation of the mitochondrial permeability transition
    • Javadov, S., Choi, A., Rajapurohitam, V., Zeidan, A., Basnakian, A. G., and Karmazyn, M. (2008). NHE-1 inhibition-induced cardioprotection against ischaemia/reperfusion is associated with attenuation of the mitochondrial permeability transition. Cardiovasc. Res. 77, 416-424.
    • (2008) Cardiovasc. Res. , vol.77 , pp. 416-424
    • Javadov, S.1    Choi, A.2    Rajapurohitam, V.3    Zeidan, A.4    Basnakian, A.G.5    Karmazyn, M.6
  • 156
    • 19344364055 scopus 로고    scopus 로고
    • MnSOD in mouse heart: acute responses to ischemic preconditioning and ischemia-reperfusion injury
    • Jin, Z. Q., Zhou, H. Z., Cecchini, G., Gray, M. O., and Karliner, J. S. (2005). MnSOD in mouse heart: acute responses to ischemic preconditioning and ischemia-reperfusion injury. Am. J. Physiol. Heart Circ. Physiol. 288, H2986-H2994.
    • (2005) Am. J. Physiol. Heart Circ. Physiol. , vol.288
    • Jin, Z.Q.1    Zhou, H.Z.2    Cecchini, G.3    Gray, M.O.4    Karliner, J.S.5
  • 157
    • 0142120096 scopus 로고    scopus 로고
    • Simvastatin attenuates oxidant-induced mitochondrial dysfunction in cardiac myocytes
    • Jones, S. P., Teshima, Y., Akao, M., and Marban, E. (2003). Simvastatin attenuates oxidant-induced mitochondrial dysfunction in cardiac myocytes. Circ. Res. 93, 697-699.
    • (2003) Circ. Res. , vol.93 , pp. 697-699
    • Jones, S.P.1    Teshima, Y.2    Akao, M.3    Marban, E.4
  • 159
    • 79551486239 scopus 로고    scopus 로고
    • Monoamine oxidases (MAO) in the pathogenesis of heart failure and ischemia/reperfusion injury
    • Kaludercic, N., Carpi, A., Menabo, R., Di Lisa, F., and Paolocci, N. (2010a). Monoamine oxidases (MAO) in the pathogenesis of heart failure and ischemia/reperfusion injury. Biochim. Biophys. Acta. PMID 20975995.
    • (2010) Biochim. Biophys. Acta. PMID , pp. 20975995
    • Kaludercic, N.1    Carpi, A.2    Menabo, R.3    Di Lisa, F.4    Paolocci, N.5
  • 161
    • 50849098175 scopus 로고    scopus 로고
    • Mitochondrial signaling in mammalian cells activated by red and near-IR radiation
    • Karu, T. I. (2008). Mitochondrial signaling in mammalian cells activated by red and near-IR radiation. Photochem. Photobiol. 84, 1091-1099.
    • (2008) Photochem. Photobiol. , vol.84 , pp. 1091-1099
    • Karu, T.I.1
  • 162
    • 9144264264 scopus 로고    scopus 로고
    • A novel mitochondrial signaling pathway activated by visible-to-near infrared radiation
    • Karu, T. I., Pyatibrat, L. V., and Afanasyeva, N. I. (2004). A novel mitochondrial signaling pathway activated by visible-to-near infrared radiation. Photochem. Photobiol. 80, 366-372.
    • (2004) Photochem. Photobiol. , vol.80 , pp. 366-372
    • Karu, T.I.1    Pyatibrat, L.V.2    Afanasyeva, N.I.3
  • 163
    • 0028943928 scopus 로고
    • Irradiation with He-Ne laser increases ATP level in cells cultivated in vitro
    • Karu, T., Pyatibrat, L., and Kalendo, G. (1995). Irradiation with He-Ne laser increases ATP level in cells cultivated in vitro. J. Photochem. Photobiol. B Biol. 27, 219-223.
    • (1995) J. Photochem. Photobiol. B Biol. , vol.27 , pp. 219-223
    • Karu, T.1    Pyatibrat, L.2    Kalendo, G.3
  • 164
    • 0030915657 scopus 로고    scopus 로고
    • Protection by hypoxic preconditioning against hypoxia-reoxygenation injury in guinea-pig papillary muscles
    • Kasamaki, Y., Guo, A. C., and McDonald, T. F. (1997). Protection by hypoxic preconditioning against hypoxia-reoxygenation injury in guinea-pig papillary muscles. Cardiovasc. Res. 34, 313-322.
    • (1997) Cardiovasc. Res. , vol.34 , pp. 313-322
    • Kasamaki, Y.1    Guo, A.C.2    McDonald, T.F.3
  • 165
    • 0024496705 scopus 로고
    • Relation between phosphate metabolites and oxygen consumption of heart in vivo
    • Katz, L. A., Swain, J. A., Portman, M. A., and Balaban, R. S. (1989). Relation between phosphate metabolites and oxygen consumption of heart in vivo. Am. J. Physiol. 256(Pt 2), H265-H274.
    • (1989) Am. J. Physiol. , vol.256 , Issue.PART 2
    • Katz, L.A.1    Swain, J.A.2    Portman, M.A.3    Balaban, R.S.4
  • 166
    • 0028346366 scopus 로고
    • Characterization of the malonyl-CoA-sensitive carnitine palmitoyltransferase (CPTo) of a rat heart mitochondrial particle Evidence that the catalytic unit is CPTi
    • Kerner, J., Zaluzec, E., Gage, D., and Bieber, L. L. (1994). Characterization of the malonyl-CoA-sensitive carnitine palmitoyltransferase (CPTo) of a rat heart mitochondrial particle. Evidence that the catalytic unit is CPTi. J. Biol. Chem. 269, 8209-8219.
    • (1994) J. Biol. Chem. , vol.269 , pp. 8209-8219
    • Kerner, J.1    Zaluzec, E.2    Gage, D.3    Bieber, L.L.4
  • 167
    • 0037305128 scopus 로고    scopus 로고
    • Ischemic preconditioning alters real-time measure of O2 radicals in intact hearts with ischemia and reperfusion
    • Kevin, L. G., Camara, A. K., Riess, M. L., Novalija, E., and Stowe, D. F. (2003). Ischemic preconditioning alters real-time measure of O2 radicals in intact hearts with ischemia and reperfusion. Am. J. Physiol. Heart Circ. Physiol. 284, H566-H574.
    • (2003) Am. J. Physiol. Heart Circ. Physiol. , vol.284
    • Kevin, L.G.1    Camara, A.K.2    Riess, M.L.3    Novalija, E.4    Stowe, D.F.5
  • 169
    • 0042330416 scopus 로고    scopus 로고
    • Role of apoptosis-inducing factor in myocardial cell death by ischemia-reperfusion
    • Kim, G. T., Chun, Y. S., Park, J. W., and Kim, M. S. (2003). Role of apoptosis-inducing factor in myocardial cell death by ischemia-reperfusion. Biochem. Biophys. Res. Commun. 309, 619-624.
    • (2003) Biochem. Biophys. Res. Commun. , vol.309 , pp. 619-624
    • Kim, G.T.1    Chun, Y.S.2    Park, J.W.3    Kim, M.S.4
  • 170
    • 0032971430 scopus 로고    scopus 로고
    • Nitric oxide as a bifunctional regulator of apoptosis
    • Kim, Y. M., Bombeck, C. A., and Billiar, T. R. (1999). Nitric oxide as a bifunctional regulator of apoptosis. Circ. Res. 84, 253-256.
    • (1999) Circ. Res. , vol.84 , pp. 253-256
    • Kim, Y.M.1    Bombeck, C.A.2    Billiar, T.R.3
  • 171
    • 9444263079 scopus 로고    scopus 로고
    • Hydrogen sulfide protects neurons from oxidative stress
    • Kimura, Y., and Kimura, H. (2004). Hydrogen sulfide protects neurons from oxidative stress. FASEB J. 18, 1165-1167.
    • (2004) FASEB J , vol.18 , pp. 1165-1167
    • Kimura, Y.1    Kimura, H.2
  • 173
    • 77649088425 scopus 로고    scopus 로고
    • Metabolic therapy at the crossroad: how to optimize myocardial substrate utilization? Trends Cardiovasc
    • Kolwicz, S. C. Jr., and Tian, R. (2009). Metabolic therapy at the crossroad: how to optimize myocardial substrate utilization? Trends Cardiovasc. Med. 19, 201-207.
    • (2009) Med , vol.19 , pp. 201-207
    • Kolwicz Jr., S.C.1    Tian, R.2
  • 175
    • 20444368852 scopus 로고    scopus 로고
    • Regulation of oxidative phosphorylation in intact mammalian heart in vivo
    • Korzeniewski, B., Noma, A., and Matsuoka, S. (2005). Regulation of oxidative phosphorylation in intact mammalian heart in vivo. Biophys. Chem. 116, 145-157.
    • (2005) Biophys. Chem. , vol.116 , pp. 145-157
    • Korzeniewski, B.1    Noma, A.2    Matsuoka, S.3
  • 176
    • 33845977959 scopus 로고    scopus 로고
    • Mitochondrial membrane permeabilization in cell death
    • Kroemer, G., Galluzzi, L., and Brenner, C. (2007). Mitochondrial membrane permeabilization in cell death. Physiol. Rev. 87, 99-163.
    • (2007) Physiol. Rev. , vol.87 , pp. 99-163
    • Kroemer, G.1    Galluzzi, L.2    Brenner, C.3
  • 177
    • 37249087334 scopus 로고    scopus 로고
    • The mitochondrial respiratory chain is a modulator of apoptosis
    • Kwong, J. Q., Henning, M. S., Starkov, A. A., and Manfredi, G. (2007). The mitochondrial respiratory chain is a modulator of apoptosis. J. Cell Biol. 179, 1163-1177.
    • (2007) J. Cell Biol. , vol.179 , pp. 1163-1177
    • Kwong, J.Q.1    Henning, M.S.2    Starkov, A.A.3    Manfredi, G.4
  • 178
    • 33947189604 scopus 로고    scopus 로고
    • Anti-anginal effects of partial fatty acid oxidation inhibitors
    • Lam, A., and Lopaschuk, G. D. (2007). Anti-anginal effects of partial fatty acid oxidation inhibitors. Curr. Opin. Pharmacol. 7, 179-185.
    • (2007) Curr. Opin. Pharmacol. , vol.7 , pp. 179-185
    • Lam, A.1    Lopaschuk, G.D.2
  • 181
    • 36749100945 scopus 로고    scopus 로고
    • A new gaseous signaling molecule emerges: cardioprotective role of hydrogen sulfide
    • Lefer, D. J. (2007). A new gaseous signaling molecule emerges: cardioprotective role of hydrogen sulfide. Proc. Natl. Acad. Sci. U.S.A. 104, 17907-17908.
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 17907-17908
    • Lefer, D.J.1
  • 183
    • 77949634569 scopus 로고    scopus 로고
    • Structure and organization of mitochondrial respiratory complexes: a new understanding of an old subject
    • Lenaz, G., and Genova, M. L. (2010). Structure and organization of mitochondrial respiratory complexes: a new understanding of an old subject. Antioxid. Redox Signal. 12, 961-1008.
    • (2010) Antioxid. Redox Signal. , vol.12 , pp. 961-1008
    • Lenaz, G.1    Genova, M.L.2
  • 184
    • 0031604554 scopus 로고    scopus 로고
    • Structural organization and transcription regulation of nuclear genes encoding the mammalian cytochrome c oxidase complex
    • Lenka, N., Vijayasarathy, C., Mullick, J., and Avadhani, N. G. (1998). Structural organization and transcription regulation of nuclear genes encoding the mammalian cytochrome c oxidase complex. Prog. Nucleic Acid Res. Mol. Biol. 61, 309-344.
    • (1998) Prog. Nucleic Acid Res. Mol. Biol. , vol.61 , pp. 309-344
    • Lenka, N.1    Vijayasarathy, C.2    Mullick, J.3    Avadhani, N.G.4
  • 185
    • 0034960785 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in cardiac disease: ischemia - reperfusion, aging, and heart failure
    • Lesnefsky, E. J., Moghaddas, S., Tandler, B., Kerner, J., and Hoppel, C. L. (2001). Mitochondrial dysfunction in cardiac disease: ischemia - reperfusion, aging, and heart failure. J. Mol. Cell. Cardiol. 33, 1065-1089.
    • (2001) J. Mol. Cell. Cardiol. , vol.33 , pp. 1065-1089
    • Lesnefsky, E.J.1    Moghaddas, S.2    Tandler, B.3    Kerner, J.4    Hoppel, C.L.5
  • 186
    • 0025375241 scopus 로고
    • Deferoxamine pretreatment reduces canine infarct size and oxidative injury
    • Lesnefsky, E. J., Repine, J. E., and Horwitz, L. D. (1990). Deferoxamine pretreatment reduces canine infarct size and oxidative injury. J. Pharmacol. Exp. Ther. 253, 1103-1109.
    • (1990) J. Pharmacol. Exp. Ther. , vol.253 , pp. 1103-1109
    • Lesnefsky, E.J.1    Repine, J.E.2    Horwitz, L.D.3
  • 187
    • 73449142511 scopus 로고    scopus 로고
    • Attenuation of myocardial apoptosis by alpha-lipoic acid through suppression of mitochondrial oxidative stress to reduce diabetic cardiomyopathy
    • Li, C. J., Zhang, Q. M., Li, M. Z., Zhang, J. Y., Yu, P., and Yu, D. M. (2009). Attenuation of myocardial apoptosis by alpha-lipoic acid through suppression of mitochondrial oxidative stress to reduce diabetic cardiomyopathy. Chin. Med. J. 122, 2580-2586.
    • (2009) Chin. Med. J. , vol.122 , pp. 2580-2586
    • Li, C.J.1    Zhang, Q.M.2    Li, M.Z.3    Zhang, J.Y.4    Yu, P.5    Yu, D.M.6
  • 188
    • 76749157966 scopus 로고    scopus 로고
    • miR-30 regulates mitochondrial fission through targeting p53 and the dynamin-related protein-1 pathway
    • doi: 10.1371/journal.pgen.1000795
    • Li, J., Donath, S., Li, Y., Qin, D., Prabhakar, B. S., and Li, P. (2010). miR-30 regulates mitochondrial fission through targeting p53 and the dynamin-related protein-1 pathway. PLoS Genet. 6, e1000795. doi: 10.1371/journal.pgen.1000795
    • (2010) PLoS Genet , vol.6
    • Li, J.1    Donath, S.2    Li, Y.3    Qin, D.4    Prabhakar, B.S.5    Li, P.6
  • 189
    • 28744436967 scopus 로고    scopus 로고
    • A possible cooperation of SOD1 and cytochrome c in mitochondria-dependent apoptosis. Free Radic
    • Li, Q., Sato, E. F., Kira, Y., Nishikawa, M., Utsumi, K., and Inoue, M. (2006). A possible cooperation of SOD1 and cytochrome c in mitochondria-dependent apoptosis. Free Radic. Biol. Med. 40, 173-181.
    • (2006) Biol. Med. , vol.40 , pp. 173-181
    • Li, Q.1    Sato, E.F.2    Kira, Y.3    Nishikawa, M.4    Utsumi, K.5    Inoue, M.6
  • 190
    • 0038333246 scopus 로고    scopus 로고
    • Deferoxamine improves early postresuscitation reperfusion after prolonged cardiac arrest in rats
    • Liachenko, S., Tang, P., and Xu, Y. (2003). Deferoxamine improves early postresuscitation reperfusion after prolonged cardiac arrest in rats. J. Cereb. Blood Flow Metab. 23, 574-581.
    • (2003) J. Cereb. Blood Flow Metab. , vol.23 , pp. 574-581
    • Liachenko, S.1    Tang, P.2    Xu, Y.3
  • 191
    • 77957751549 scopus 로고    scopus 로고
    • SOD1 and MitoTEMPO partially prevent MPTP, necrosis and mitochondrial apoptosis following ATP depletion-recovery
    • Liang, H. L., Sedlic, F., Bosnjak, Z., and Nilakantan, V. (2010). SOD1 and MitoTEMPO partially prevent MPTP, necrosis and mitochondrial apoptosis following ATP depletion-recovery. Free Radic. Biol. Med. 49, 1550-1560.
    • (2010) Free Radic. Biol. Med. , vol.49 , pp. 1550-1560
    • Liang, H.L.1    Sedlic, F.2    Bosnjak, Z.3    Nilakantan, V.4
  • 192
    • 33750347347 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
    • Lin, M. T., and Beal, M. F. (2006). Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 443, 787-795.
    • (2006) Nature , vol.443 , pp. 787-795
    • Lin, M.T.1    Beal, M.F.2
  • 193
    • 30044434360 scopus 로고    scopus 로고
    • The mitochondrial theory of aging and its relationship to reactive oxygen species damage and somatic mtDNA mutations
    • Loeb, L. A., Wallace, D. C., and Martin, G. M. (2005). The mitochondrial theory of aging and its relationship to reactive oxygen species damage and somatic mtDNA mutations. Proc. Natl. Acad. Sci. U.S.A. 102, 18769-18770.
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 18769-18770
    • Loeb, L.A.1    Wallace, D.C.2    Martin, G.M.3
  • 194
    • 67649265352 scopus 로고    scopus 로고
    • Enhancement of nitric oxide release from nitrosyl hemoglobin and nitrosyl myoglobin by red/near infrared radiation: potential role in cardioprotection
    • Lohr, N. L., Keszler, A., Pratt, P., Bienengraber, M., Warltier, D. C., and Hogg, N. (2009). Enhancement of nitric oxide release from nitrosyl hemoglobin and nitrosyl myoglobin by red/near infrared radiation: potential role in cardioprotection. J. Mol. Cell. Cardiol. 47, 256-263.
    • (2009) J. Mol. Cell. Cardiol. , vol.47 , pp. 256-263
    • Lohr, N.L.1    Keszler, A.2    Pratt, P.3    Bienengraber, M.4    Warltier, D.C.5    Hogg, N.6
  • 195
    • 77955871829 scopus 로고    scopus 로고
    • PGC-1alpha regulates expression of myocardial mitochondrial antioxidants and myocardial oxidative stress after chronic systolic overload
    • Lu, Z., Xu, X., Hu, X., Fassett, J., Zhu, G., Tao, Y., Li, J., Huang, Y., Zhang, P., Zhao, B., and Chen, Y. (2010). PGC-1alpha regulates expression of myocardial mitochondrial antioxidants and myocardial oxidative stress after chronic systolic overload. Antioxid. Redox Signal. 13, 1011-1022.
    • (2010) Antioxid. Redox Signal. , vol.13 , pp. 1011-1022
    • Lu, Z.1    Xu, X.2    Hu, X.3    Fassett, J.4    Zhu, G.5    Tao, Y.6    Li, J.7    Huang, Y.8    Zhang, P.9    Zhao, B.10    Chen, Y.11
  • 196
    • 48849088862 scopus 로고    scopus 로고
    • Darbepoetin alfa exerts a cardioprotective effect in autoimmune cardiomyopathy via reduction of ER stress and activation of the PI3K/Akt and STAT3 pathways
    • Mao, W., Iwai, C., Liu, J., Sheu, S. S., Fu, M., and Liang, C. S. (2008). Darbepoetin alfa exerts a cardioprotective effect in autoimmune cardiomyopathy via reduction of ER stress and activation of the PI3K/Akt and STAT3 pathways. J. Mol. Cell. Cardiol. 45, 250-260.
    • (2008) J. Mol. Cell. Cardiol. , vol.45 , pp. 250-260
    • Mao, W.1    Iwai, C.2    Liu, J.3    Sheu, S.S.4    Fu, M.5    Liang, C.S.6
  • 197
    • 41249086364 scopus 로고    scopus 로고
    • Mitochondrial centrality in heart failure
    • Marin-Garcia, J., and Goldenthal, M. J. (2008). Mitochondrial centrality in heart failure. Heart Fail. Rev. 13, 137-150.
    • (2008) Heart Fail. Rev. , vol.13 , pp. 137-150
    • Marin-Garcia, J.1    Goldenthal, M.J.2
  • 198
    • 57449103542 scopus 로고    scopus 로고
    • Reactivity of ubiquinone and ubiquinol with superoxide and the hydroperoxyl radical: implications for in vivo antioxidant activity
    • Maroz, A., Anderson, R. F., Smith, R. A., and Murphy, M. P. (2009). Reactivity of ubiquinone and ubiquinol with superoxide and the hydroperoxyl radical: implications for in vivo antioxidant activity. Free Radic. Biol. Med. 46, 105-109.
    • (2009) Free Radic. Biol. Med. , vol.46 , pp. 105-109
    • Maroz, A.1    Anderson, R.F.2    Smith, R.A.3    Murphy, M.P.4
  • 201
    • 60249083822 scopus 로고    scopus 로고
    • Hexokinase-2 bound to mitochondria: cancer's stygian link to the "Warburg Effect" and a pivotal target for effective therapy
    • Mathupala, S. P., Ko, Y. H., and Pedersen, P. L. (2009). Hexokinase-2 bound to mitochondria: cancer's stygian link to the "Warburg Effect" and a pivotal target for effective therapy. Semin. Cancer Biol. 19, 17-24.
    • (2009) Semin. Cancer Biol. , vol.19 , pp. 17-24
    • Mathupala, S.P.1    Ko, Y.H.2    Pedersen, P.L.3
  • 202
    • 70449507674 scopus 로고    scopus 로고
    • Therapeutic targets and limits of minocycline neuroprotection in experimental ischemic stroke
    • doi: 10.1186/1471-2202-10-126
    • Matsukawa, N., Yasuhara, T., Hara, K., Xu, L., Maki, M., Yu, G., Kaneko, Y., Ojika, K., Hess, D. C., and Borlongan, C. V. (2009). Therapeutic targets and limits of minocycline neuroprotection in experimental ischemic stroke. BMC Neurosci. 10, 126. doi: 10.1186/1471-2202-10-126
    • (2009) BMC Neurosci , vol.10 , pp. 126
    • Matsukawa, N.1    Yasuhara, T.2    Hara, K.3    Xu, L.4    Maki, M.5    Yu, G.6    Kaneko, Y.7    Ojika, K.8    Hess, D.C.9    Borlongan, C.V.10
  • 203
    • 33746016268 scopus 로고    scopus 로고
    • Mitochondria: more than just a powerhouse
    • McBride, H. M., Neuspiel, M., and Wasiak, S. (2006). Mitochondria: more than just a powerhouse. Curr. Biol. 16, R551-R560.
    • (2006) Curr. Biol. , vol.16
    • McBride, H.M.1    Neuspiel, M.2    Wasiak, S.3
  • 204
    • 0025319665 scopus 로고
    • Role of calcium ions in regulation of mammalian intramitochondrial metabolism
    • McCormack, J. G., Halestrap, A. P., and Denton, R. M. (1990). Role of calcium ions in regulation of mammalian intramitochondrial metabolism. Physiol. Rev. 70, 391-425.
    • (1990) Physiol. Rev. , vol.70 , pp. 391-425
    • McCormack, J.G.1    Halestrap, A.P.2    Denton, R.M.3
  • 205
    • 33846001693 scopus 로고    scopus 로고
    • Mitochondrial creatine kinase activity prevents reactive oxygen species generation: antioxidant role of mitochondrial kinase-dependent ADP re-cycling activity
    • Meyer, L. E., Machado, L. B., Santiago, A. P., da-Silva, W. S., De Felice, F. G., Holub, O., Oliveira, M. F., and Galina, A. (2006). Mitochondrial creatine kinase activity prevents reactive oxygen species generation: antioxidant role of mitochondrial kinase-dependent ADP re-cycling activity. J. Biol. Chem. 281, 37361-37371.
    • (2006) J. Biol. Chem. , vol.281 , pp. 37361-37371
    • Meyer, L.E.1    Machado, L.B.2    Santiago, A.P.3    da-Silva, W.S.4    De Felice, F.G.5    Holub, O.6    Oliveira, M.F.7    Galina, A.8
  • 206
    • 34447131490 scopus 로고    scopus 로고
    • Targeting antioxidants to mitochondria and cardiovascular diseases: the effects of mitoquinone
    • Milagros Rocha, M., and Victor, V. M. (2007). Targeting antioxidants to mitochondria and cardiovascular diseases: the effects of mitoquinone. Med. Sci. Monit. 13, RA132-RA145.
    • (2007) Med. Sci. Monit. , vol.13
    • Milagros Rocha, M.1    Victor, V.M.2
  • 207
    • 2342596461 scopus 로고    scopus 로고
    • Evidence for resveratrol-induced preservation of brain mitochondria functions after hypoxia-reoxygenation
    • Morin, C., Zini, R., Albengres, E., Bertelli, A. A., Bertelli, A., and Tillement, J. P. (2003a). Evidence for resveratrol-induced preservation of brain mitochondria functions after hypoxia-reoxygenation. Drugs Exp. Clin. Res. 29, 227-233.
    • (2003) Drugs Exp. Clin. Res. , vol.29 , pp. 227-233
    • Morin, C.1    Zini, R.2    Albengres, E.3    Bertelli, A.A.4    Bertelli, A.5    Tillement, J.P.6
  • 208
    • 0042672589 scopus 로고    scopus 로고
    • Anoxia-reoxygenation-induced cytochrome c and cardiolipin release from rat brain mitochondria
    • Morin, C., Zini, R., and Tillement, J. P. (2003b). Anoxia-reoxygenation-induced cytochrome c and cardiolipin release from rat brain mitochondria. Biochem. Biophys. Res. Commun. 307, 477-482.
    • (2003) Biochem. Biophys. Res. Commun. , vol.307 , pp. 477-482
    • Morin, C.1    Zini, R.2    Tillement, J.P.3
  • 209
    • 70450180180 scopus 로고    scopus 로고
    • Inhibition of mitochondrial membrane permeability as a putative pharmacological target for cardioprotection
    • Morin, D., Assaly, R., Paradis, S., and Berdeaux, A. (2009). Inhibition of mitochondrial membrane permeability as a putative pharmacological target for cardioprotection. Curr. Med. Chem. 16, 4382-4398.
    • (2009) Curr. Med. Chem. , vol.16 , pp. 4382-4398
    • Morin, D.1    Assaly, R.2    Paradis, S.3    Berdeaux, A.4
  • 210
    • 48249146621 scopus 로고    scopus 로고
    • Fatty acid oxidation and insulin action: when less is more
    • Muoio, D. M., and Newgard, C. B. (2008). Fatty acid oxidation and insulin action: when less is more. Diabetes 57, 1455-1456.
    • (2008) Diabetes , vol.57 , pp. 1455-1456
    • Muoio, D.M.1    Newgard, C.B.2
  • 211
    • 0035834824 scopus 로고    scopus 로고
    • 2+ overload during simulated ischemia and reperfusion: possible mechanism of cardioprotection
    • 2+ overload during simulated ischemia and reperfusion: possible mechanism of cardioprotection. Circ. Res. 89, 891-898.
    • (2001) Circ. Res. , vol.89 , pp. 891-898
    • Murata, M.1    Akao, M.2    O'Rourke, B.3    Marban, E.4
  • 212
    • 33749171401 scopus 로고    scopus 로고
    • Clinical implications of mitochondrial dysfunction
    • Muravchick, S., and Levy, R. J. (2006). Clinical implications of mitochondrial dysfunction. Anesthesiology 105, 819-837.
    • (2006) Anesthesiology , vol.105 , pp. 819-837
    • Muravchick, S.1    Levy, R.J.2
  • 214
    • 34047142614 scopus 로고    scopus 로고
    • Cardioprotection and mitochondrial S-nitrosation: effects of S-nitroso-2-mercaptopropionyl glycine (SNO-MPG) in cardiac ischemia-reperfusion injury
    • Nadtochiy, S. M., Burwell, L. S., and Brookes, P. S. (2007). Cardioprotection and mitochondrial S-nitrosation: effects of S-nitroso-2-mercaptopropionyl glycine (SNO-MPG) in cardiac ischemia-reperfusion injury. J. Mol. Cell. Cardiol. 42, 812-825.
    • (2007) J. Mol. Cell. Cardiol. , vol.42 , pp. 812-825
    • Nadtochiy, S.M.1    Burwell, L.S.2    Brookes, P.S.3
  • 215
    • 76949089544 scopus 로고    scopus 로고
    • Brain mitochondrial dysfunction and oxidative damage in Parkinson's disease
    • Navarro, A., and Boveris, A. (2009). Brain mitochondrial dysfunction and oxidative damage in Parkinson's disease. J. Bioenerg. Biomembr. 41, 517-521.
    • (2009) J. Bioenerg. Biomembr. , vol.41 , pp. 517-521
    • Navarro, A.1    Boveris, A.2
  • 216
    • 78650275547 scopus 로고    scopus 로고
    • Nitric oxide/reactive oxygen species generation and nitroso/ redox imbalance in heart failure: from molecular mechanisms to therapeutic implications
    • Nediani, C., Raimondi, L., Borchi, E., and Cerbai, E. (2011). Nitric oxide/reactive oxygen species generation and nitroso/ redox imbalance in heart failure: from molecular mechanisms to therapeutic implications. Antioxid. Redox Signal. 14, 289-331.
    • (2011) Antioxid. Redox Signal. , vol.14 , pp. 289-331
    • Nediani, C.1    Raimondi, L.2    Borchi, E.3    Cerbai, E.4
  • 217
    • 0015349584 scopus 로고
    • The effects of increased heart work on the tricarboxylate cycle and its interactions with glycolysis in the perfused rat heart
    • Neely, J. R., Denton, R. M., England, P. J., and Randle, P. J. (1972). The effects of increased heart work on the tricarboxylate cycle and its interactions with glycolysis in the perfused rat heart. Biochem. J. 128, 147-159.
    • (1972) Biochem. J. , vol.128 , pp. 147-159
    • Neely, J.R.1    Denton, R.M.2    England, P.J.3    Randle, P.J.4
  • 218
    • 1842389677 scopus 로고
    • Relationship between carbohydrate and lipid metabolism and the energy balance of heart muscle
    • Neely, J. R., and Morgan, H. E. (1974). Relationship between carbohydrate and lipid metabolism and the energy balance of heart muscle. Annu. Rev. Physiol. 36, 413-459.
    • (1974) Annu. Rev. Physiol. , vol.36 , pp. 413-459
    • Neely, J.R.1    Morgan, H.E.2
  • 219
    • 33947239659 scopus 로고    scopus 로고
    • The failing heart-an engine out of fuel
    • Neubauer, S. (2007). The failing heart-an engine out of fuel. N. Engl. J. Med. 356, 1140-1151.
    • (2007) N. Engl. J. Med. , vol.356 , pp. 1140-1151
    • Neubauer, S.1
  • 220
    • 0004097211 scopus 로고
    • Chapter 5 London: John Wiley and Sons. Nicholls, D., and Fergunson, S. J. (2002). Bioenergetics. London: Academic Press
    • Newsholm, E., and Start, C. (1973). Regulation in Metabolism, Chapter 5. London: John Wiley and Sons. Nicholls, D., and Fergunson, S. J. (2002). Bioenergetics. London: Academic Press.
    • (1973) Regulation in Metabolism
    • Newsholm, E.1    Start, C.2
  • 222
    • 77952298503 scopus 로고    scopus 로고
    • Mitochondrial regulation of cell death: processing of apoptosis-inducing factor (AIF)
    • Norberg, E., Orrenius, S., and Zhivotovsky, B. (2010). Mitochondrial regulation of cell death: processing of apoptosis-inducing factor (AIF). Biochem. Biophys. Res. Commun. 396, 95-100.
    • (2010) Biochem. Biophys. Res. Commun. , vol.396 , pp. 95-100
    • Norberg, E.1    Orrenius, S.2    Zhivotovsky, B.3
  • 223
    • 0031852076 scopus 로고    scopus 로고
    • Mechanisms of cardioprotection by peroxynitrite in myocardial ischemia and reperfusion injury
    • Nossuli, T. O., Hayward, R., Jensen, D., Scalia, R., and Lefer, A. M. (1998). Mechanisms of cardioprotection by peroxynitrite in myocardial ischemia and reperfusion injury. Am. J. Physiol. 275(Pt 2), H509-H519.
    • (1998) Am. J. Physiol. , vol.275 , Issue.PART 2
    • Nossuli, T.O.1    Hayward, R.2    Jensen, D.3    Scalia, R.4    Lefer, A.M.5
  • 225
    • 77954723691 scopus 로고    scopus 로고
    • Resurrecting hope for antioxidant treatment of cardiovascular disease: focus on mitochondria
    • O'Connor, P. M., and Gutterman, D. D. (2010). Resurrecting hope for antioxidant treatment of cardiovascular disease: focus on mitochondria. Circ. Res. 107, 9-11.
    • (2010) Circ. Res. , vol.107 , pp. 9-11
    • O'Connor, P.M.1    Gutterman, D.D.2
  • 227
    • 77956795824 scopus 로고    scopus 로고
    • Mitochondrial morphology and cardiovascular disease
    • Ong, S. B., and Hausenloy, D. J. (2010). Mitochondrial morphology and cardiovascular disease. Cardiovasc. Res. 88, 16-29.
    • (2010) Cardiovasc. Res. , vol.88 , pp. 16-29
    • Ong, S.B.1    Hausenloy, D.J.2
  • 229
    • 0013804969 scopus 로고
    • Coronary flow rate and perfusion pressure as determinants of mechanical function and oxidative metabolism of isolated perfused rat heart
    • Opie, L. H. (1965). Coronary flow rate and perfusion pressure as determinants of mechanical function and oxidative metabolism of isolated perfused rat heart. J. Physiol. 180, 529-541.
    • (1965) J. Physiol. , vol.180 , pp. 529-541
    • Opie, L.H.1
  • 230
    • 0015893630 scopus 로고
    • Regulation of fatty acid utilization in isolated perfused rat hearts
    • Oram, J. F., Bennetch, S. L., and Neely, J. R. (1973). Regulation of fatty acid utilization in isolated perfused rat hearts. J. Biol. Chem. 248, 5299-5309.
    • (1973) J. Biol. Chem. , vol.248 , pp. 5299-5309
    • Oram, J.F.1    Bennetch, S.L.2    Neely, J.R.3
  • 232
    • 33947388409 scopus 로고    scopus 로고
    • Mitochondrial ion channels
    • O'Rourke, B. (2007). Mitochondrial ion channels. Annu. Rev. Physiol. 69, 19-49.
    • (2007) Annu. Rev. Physiol. , vol.69 , pp. 19-49
    • O'Rourke, B.1
  • 233
    • 33750330039 scopus 로고    scopus 로고
    • Regulation of cytochrome C peroxidase activity by nitric oxide and laser irradiation
    • Osipov, A. N., Stepanov, G. O., Vladimirov, Y. A., Kozlov, A. V., and Kagan, V. E. (2006). Regulation of cytochrome C peroxidase activity by nitric oxide and laser irradiation. Biochemistry (Mosc). 71, 1128-1132.
    • (2006) Biochemistry (Mosc) , vol.71 , pp. 1128-1132
    • Osipov, A.N.1    Stepanov, G.O.2    Vladimirov, Y.A.3    Kozlov, A.V.4    Kagan, V.E.5
  • 234
    • 0037881908 scopus 로고    scopus 로고
    • A novel NADH kinase is the mitochondrial source of NADPH in Saccharomyces cerevisiae
    • Outten, C. E., and Culotta, V. C. (2003). A novel NADH kinase is the mitochondrial source of NADPH in Saccharomyces cerevisiae. EMBO J. 22, 2015-2024.
    • (2003) EMBO J , vol.22 , pp. 2015-2024
    • Outten, C.E.1    Culotta, V.C.2
  • 235
    • 0034659785 scopus 로고    scopus 로고
    • Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain
    • Owen, M. R., Doran, E., and Halestrap, A. P. (2000). Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain. Biochem. J. 348(Pt 3), 607-614.
    • (2000) Biochem. J. , vol.348 , Issue.PART 3 , pp. 607-614
    • Owen, M.R.1    Doran, E.2    Halestrap, A.P.3
  • 238
    • 0346059551 scopus 로고    scopus 로고
    • Decrease in mitochondrial complex I activity in ischemic/reperfused rat heart: involvement of reactive oxygen species and cardiolipin
    • Paradies, G., Petrosillo, G., Pistolese, M., Di Venosa, N., Federici, A., and Ruggiero, F. M. (2004). Decrease in mitochondrial complex I activity in ischemic/reperfused rat heart: involvement of reactive oxygen species and cardiolipin. Circ. Res. 94, 53-59.
    • (2004) Circ. Res. , vol.94 , pp. 53-59
    • Paradies, G.1    Petrosillo, G.2    Pistolese, M.3    Di Venosa, N.4    Federici, A.5    Ruggiero, F.M.6
  • 239
    • 0030929650 scopus 로고    scopus 로고
    • Cardiolipin-dependent decrease of cytochrome c oxidase activity in heart mitochondria from hypothyroid rats
    • Paradies, G., Petrosillo, G., and Ruggiero, F. M. (1997). Cardiolipin-dependent decrease of cytochrome c oxidase activity in heart mitochondria from hypothyroid rats. Biochim. Biophys. Acta 1319, 5-8.
    • (1997) Biochim. Biophys. Acta , vol.1319 , pp. 5-8
    • Paradies, G.1    Petrosillo, G.2    Ruggiero, F.M.3
  • 240
    • 52449119836 scopus 로고    scopus 로고
    • Regulation of hexokinase binding to VDAC
    • Pastorino, J. G., and Hoek, J. B. (2008). Regulation of hexokinase binding to VDAC. J. Bioenerg. Biomembr. 40, 171-182.
    • (2008) J. Bioenerg. Biomembr. , vol.40 , pp. 171-182
    • Pastorino, J.G.1    Hoek, J.B.2
  • 241
    • 28544436922 scopus 로고    scopus 로고
    • Activation of glycogen synthase kinase 3beta disrupts the binding of hexokinase II to mitochondria by phosphorylating voltage-dependent anion channel and potentiates chemotherapy-induced cytotoxicity
    • Pastorino, J. G., Hoek, J. B., and Shulga, N. (2005). Activation of glycogen synthase kinase 3beta disrupts the binding of hexokinase II to mitochondria by phosphorylating voltage-dependent anion channel and potentiates chemotherapy-induced cytotoxicity. Cancer Res. 65, 10545-10554.
    • (2005) Cancer Res , vol.65 , pp. 10545-10554
    • Pastorino, J.G.1    Hoek, J.B.2    Shulga, N.3
  • 242
    • 0037056002 scopus 로고    scopus 로고
    • Mitochondrial bound type II hexokinase: a key player in the growth and survival of many cancers and an ideal prospect for therapeutic intervention
    • Pedersen, P. L., Mathupala, S., Rempel, A., Geschwind, J. F., and Ko, Y. H. (2002). Mitochondrial bound type II hexokinase: a key player in the growth and survival of many cancers and an ideal prospect for therapeutic intervention. Biochim. Biophys. Acta 1555, 14-20.
    • (2002) Biochim. Biophys. Acta , vol.1555 , pp. 14-20
    • Pedersen, P.L.1    Mathupala, S.2    Rempel, A.3    Geschwind, J.F.4    Ko, Y.H.5
  • 245
    • 70350710639 scopus 로고    scopus 로고
    • Succinyl-CoA synthetase is a phosphate target for the activation of mitochondrial metabolism
    • Phillips, D., Aponte, A. M., French, S. A., Chess, D. J., and Balaban, R. S. (2009). Succinyl-CoA synthetase is a phosphate target for the activation of mitochondrial metabolism. Biochemistry 48, 7140-7149.
    • (2009) Biochemistry , vol.48 , pp. 7140-7149
    • Phillips, D.1    Aponte, A.M.2    French, S.A.3    Chess, D.J.4    Balaban, R.S.5
  • 246
    • 58149328569 scopus 로고    scopus 로고
    • Heme oxygenase-1 regulates cardiac mitochondrial biogenesis via Nrf2-mediated transcriptional control of nuclear respiratory factor-1
    • Piantadosi, C. A., Carraway, M. S., Babiker, A., and Suliman, H. B. (2008). Heme oxygenase-1 regulates cardiac mitochondrial biogenesis via Nrf2-mediated transcriptional control of nuclear respiratory factor-1. Circ. Res. 103, 1232-1240.
    • (2008) Circ. Res. , vol.103 , pp. 1232-1240
    • Piantadosi, C.A.1    Carraway, M.S.2    Babiker, A.3    Suliman, H.B.4
  • 247
    • 75749133554 scopus 로고    scopus 로고
    • The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle
    • Piao, L., Fang, Y. H., Cadete, V. J., Wietholt, C., Urboniene, D., Toth, P. T., Marsboom, G., Zhang, H. J., Haber, I., Rehman, J., Lopaschuk, G. D., and Archer, S. L. (2010). The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle. J. Mol. Med. 88, 47-60.
    • (2010) J. Mol. Med. , vol.88 , pp. 47-60
    • Piao, L.1    Fang, Y.H.2    Cadete, V.J.3    Wietholt, C.4    Urboniene, D.5    Toth, P.T.6    Marsboom, G.7    Zhang, H.J.8    Haber, I.9    Rehman, J.10    Lopaschuk, G.D.11    Archer, S.L.12
  • 250
    • 46449083451 scopus 로고    scopus 로고
    • Oxidative stress and mitochondrial dysfunction in neurodegeneration; cardiolipin a critical target? Biochim
    • Pope, S., Land, J. M., and Heales, S. J. (2008). Oxidative stress and mitochondrial dysfunction in neurodegeneration; cardiolipin a critical target? Biochim. Biophys. Acta 1777, 794-799.
    • (2008) Biophys. Acta , vol.1777 , pp. 794-799
    • Pope, S.1    Land, J.M.2    Heales, S.J.3
  • 251
    • 77951674239 scopus 로고    scopus 로고
    • Isoflurane protects cardiomyocytes and mitochondria by immediate and cytosol-independent action at reperfusion
    • Pravdic, D., Mio, Y., Sedlic, F., Pratt, P. F., Warltier, D. C., Bosnjak, Z. J., and Bienengraeber, M. (2010). Isoflurane protects cardiomyocytes and mitochondria by immediate and cytosol-independent action at reperfusion. Br. J. Pharmacol. 160, 220-232.
    • (2010) Br. J. Pharmacol. , vol.160 , pp. 220-232
    • Pravdic, D.1    Mio, Y.2    Sedlic, F.3    Pratt, P.F.4    Warltier, D.C.5    Bosnjak, Z.J.6    Bienengraeber, M.7
  • 253
    • 0032452225 scopus 로고    scopus 로고
    • Regulatory interactions between lipids and carbohydrates: the glucose fatty acid cycle after 35 years
    • Randle, P. J. (1998). Regulatory interactions between lipids and carbohydrates: the glucose fatty acid cycle after 35 years. Diabetes Metab. Rev. 14, 263-283.
    • (1998) Diabetes Metab. Rev. , vol.14 , pp. 263-283
    • Randle, P.J.1
  • 254
    • 0014787834 scopus 로고
    • Control of the tricarboxylate cycle and its interactions with glycolysis during acetate utilization in rat heart
    • Randle, P. J., England, P. J., and Denton, R. M. (1970). Control of the tricarboxylate cycle and its interactions with glycolysis during acetate utilization in rat heart. Biochem. J. 117, 677-695.
    • (1970) Biochem. J. , vol.117 , pp. 677-695
    • Randle, P.J.1    England, P.J.2    Denton, R.M.3
  • 255
    • 50549202600 scopus 로고
    • The glucose fatty-acid cycle Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus
    • Randle, P. J., Garland, P. B., Hales, C. N., and Newsholme, E. A. (1963). The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet 1, 785-789.
    • (1963) Lancet , vol.1 , pp. 785-789
    • Randle, P.J.1    Garland, P.B.2    Hales, C.N.3    Newsholme, E.A.4
  • 257
    • 0017670710 scopus 로고
    • Barium ions and excitation-contraction coupling of frog single muscle fibres under controlled current and voltage
    • Raymond, G., and Potreau, D. (1977). Barium ions and excitation-contraction coupling of frog single muscle fibres under controlled current and voltage. J. Physiol. (Paris) 73, 617-631.
    • (1977) J. Physiol. (Paris) , vol.73 , pp. 617-631
    • Raymond, G.1    Potreau, D.2
  • 260
    • 0035827635 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha selectively induces MnSOD expression via mitochondria-to-nucleus signaling, whereas interleukin-1beta utilizes an alternative pathway
    • Rogers, R. J., Monnier, J. M., and Nick, H. S. (2001). Tumor necrosis factor-alpha selectively induces MnSOD expression via mitochondria-to-nucleus signaling, whereas interleukin-1beta utilizes an alternative pathway. J. Biol. Chem. 276, 20419-20427.
    • (2001) J. Biol. Chem. , vol.276 , pp. 20419-20427
    • Rogers, R.J.1    Monnier, J.M.2    Nick, H.S.3
  • 262
    • 0033215190 scopus 로고    scopus 로고
    • The cardiovascular effects and implications of peroxynitrite
    • Ronson, R. S., Nakamura, M., and Vinten-Johansen, J. (1999). The cardiovascular effects and implications of peroxynitrite. Cardiovasc. Res. 44, 47-59.
    • (1999) Cardiovasc. Res. , vol.44 , pp. 47-59
    • Ronson, R.S.1    Nakamura, M.2    Vinten-Johansen, J.3
  • 264
    • 77956946055 scopus 로고    scopus 로고
    • The SR-mitochondria interaction: a new player in cardiac pathophysiology
    • Ruiz-Meana, M., Fernandez-Sanz, C., and Garcia-Dorado, D. (2010). The SR-mitochondria interaction: a new player in cardiac pathophysiology. Cardiovasc. Res. 88, 30-39.
    • (2010) Cardiovasc. Res. , vol.88 , pp. 30-39
    • Ruiz-Meana, M.1    Fernandez-Sanz, C.2    Garcia-Dorado, D.3
  • 268
    • 33749529425 scopus 로고    scopus 로고
    • Exploring mitochondria in the intact ischemic heart: advancing technologies to image intracellular function
    • Sack, M. N. (2006a). Exploring mitochondria in the intact ischemic heart: advancing technologies to image intracellular function. Circulation 114, 1452-1454.
    • (2006) Circulation , vol.114 , pp. 1452-1454
    • Sack, M.N.1
  • 269
    • 33749472339 scopus 로고    scopus 로고
    • Mitochondrial depolarization and the role of uncoupling proteins in ischemia tolerance
    • Sack, M. N. (2006b). Mitochondrial depolarization and the role of uncoupling proteins in ischemia tolerance. Cardiovasc. Res. 72, 210-219.
    • (2006) Cardiovasc. Res. , vol.72 , pp. 210-219
    • Sack, M.N.1
  • 270
    • 33645897315 scopus 로고    scopus 로고
    • Cardiac system bioenergetics: metabolic basis of the Frank-Starling law
    • Saks, V., Dzeja, P., Schlattner, U., Vendelin, M., Terzic, A., and Wallimann, T. (2006a). Cardiac system bioenergetics: metabolic basis of the Frank-Starling law. J. Physiol. 571(Pt 2), 253-273.
    • (2006) J. Physiol. , vol.571 , Issue.PART 2 , pp. 253-273
    • Saks, V.1    Dzeja, P.2    Schlattner, U.3    Vendelin, M.4    Terzic, A.5    Wallimann, T.6
  • 271
    • 33845335159 scopus 로고    scopus 로고
    • Molecular system bioenergetics: regulation of substrate supply in response to heart energy demands
    • Saks, V., Favier, R., Guzun, R., Schlattner, U., and Wallimann, T. (2006b). Molecular system bioenergetics: regulation of substrate supply in response to heart energy demands. J. Physiol. 577(Pt 3), 769-777.
    • (2006) J. Physiol. , vol.577 , Issue.PART 3 , pp. 769-777
    • Saks, V.1    Favier, R.2    Guzun, R.3    Schlattner, U.4    Wallimann, T.5
  • 272
    • 0034043681 scopus 로고    scopus 로고
    • Role of the creatine/ phosphocreatine system in the regulation of mitochondrial respiration
    • Saks, V. A., Kongas, O., Vendelin, M., and Kay, L. (2000). Role of the creatine/ phosphocreatine system in the regulation of mitochondrial respiration. Acta Physiol. Scand. 168, 635-641.
    • (2000) Acta Physiol. Scand. , vol.168 , pp. 635-641
    • Saks, V.A.1    Kongas, O.2    Vendelin, M.3    Kay, L.4
  • 273
    • 36348997653 scopus 로고    scopus 로고
    • Mitochondria, calcium, and calpain are key mediators of resveratrol-induced apoptosis in breast cancer
    • Sareen, D., Darjatmoko, S. R., Albert, D. M., and Polans, A. S. (2007). Mitochondria, calcium, and calpain are key mediators of resveratrol-induced apoptosis in breast cancer. Mol. Pharmacol. 72, 1466-1475.
    • (2007) Mol. Pharmacol. , vol.72 , pp. 1466-1475
    • Sareen, D.1    Darjatmoko, S.R.2    Albert, D.M.3    Polans, A.S.4
  • 275
    • 33745410626 scopus 로고    scopus 로고
    • Mitochondrial disease
    • Schapira, A. H. (2006). Mitochondrial disease. Lancet 368, 70-82.
    • (2006) Lancet , vol.368 , pp. 70-82
    • Schapira, A.H.1
  • 276
    • 24744444959 scopus 로고    scopus 로고
    • Increasing mitochondrial substrate-level phosphorylation can rescue respiratory growth of an ATP synthase-deficient yeast
    • Schwimmer, C., Lefebvre-Legendre, L., Rak, M., Devin, A., Slonimski, P. P., di Rago, J. P., and Rigoulet, M. (2005). Increasing mitochondrial substrate-level phosphorylation can rescue respiratory growth of an ATP synthase-deficient yeast. J. Biol. Chem. 280, 30751-30759.
    • (2005) J. Biol. Chem. , vol.280 , pp. 30751-30759
    • Schwimmer, C.1    Lefebvre-Legendre, L.2    Rak, M.3    Devin, A.4    Slonimski, P.P.5    di Rago, J.P.6    Rigoulet, M.7
  • 277
    • 77955551744 scopus 로고    scopus 로고
    • Monitoring mitochondrial electron fluxes using NAD(P) H-flavoprotein fluorometry reveals complex action of isoflurane on cardiomyocytes
    • Sedlic, F., Pravdic, D., Hirata, N., Mio, Y., Sepac, A., Camara, A. K., Wakatsuki, T., Bosnjak, Z. J., and Bienengraeber, M. (2010a). Monitoring mitochondrial electron fluxes using NAD(P) H-flavoprotein fluorometry reveals complex action of isoflurane on cardiomyocytes. Biochim. Biophys. Acta 1797, 1749-1758.
    • (2010) Biochim. Biophys. Acta , vol.1797 , pp. 1749-1758
    • Sedlic, F.1    Pravdic, D.2    Hirata, N.3    Mio, Y.4    Sepac, A.5    Camara, A.K.6    Wakatsuki, T.7    Bosnjak, Z.J.8    Bienengraeber, M.9
  • 279
    • 0032100603 scopus 로고    scopus 로고
    • Redox signaling and the emerging therapeutic potential of thiol antioxidants
    • Sen, C. K. (1998). Redox signaling and the emerging therapeutic potential of thiol antioxidants. Biochem. Pharmacol. 55, 1747-1758.
    • (1998) Biochem. Pharmacol. , vol.55 , pp. 1747-1758
    • Sen, C.K.1
  • 280
    • 14644412783 scopus 로고    scopus 로고
    • Brief hypoxia before normoxic reperfusion (postconditioning) protects the heart against ischemia-reperfusion injury by preventing mitochondria peroxyde production and glutathione depletion
    • Serviddio, G., Di Venosa, N., Federici, A., D'Agostino, D., Rollo, T., Prigigallo, F., Altomare, E., Fiore, T., and Vendemiale, G. (2005). Brief hypoxia before normoxic reperfusion (postconditioning) protects the heart against ischemia-reperfusion injury by preventing mitochondria peroxyde production and glutathione depletion. FASEB J. 19, 354-361.
    • (2005) FASEB J , vol.19 , pp. 354-361
    • Serviddio, G.1    Di Venosa, N.2    Federici, A.3    D'Agostino, D.4    Rollo, T.5    Prigigallo, F.6    Altomare, E.7    Fiore, T.8    Vendemiale, G.9
  • 283
    • 34548170490 scopus 로고    scopus 로고
    • Mitofusin-2 is a major determinant of oxidative stress-mediated heart muscle cell apoptosis
    • Shen, T., Zheng, M., Cao, C., Chen, C., Tang, J., Zhang, W., Cheng, H., Chen, K. H., and Xiao, R. P. (2007). Mitofusin-2 is a major determinant of oxidative stress-mediated heart muscle cell apoptosis. J. Biol. Chem. 282, 23354-23361.
    • (2007) J. Biol. Chem. , vol.282 , pp. 23354-23361
    • Shen, T.1    Zheng, M.2    Cao, C.3    Chen, C.4    Tang, J.5    Zhang, W.6    Cheng, H.7    Chen, K.H.8    Xiao, R.P.9
  • 284
    • 0033595780 scopus 로고    scopus 로고
    • Loss of molecular interaction between cytochrome c and cardiolipin due to lipid peroxidation
    • Shidoji, Y., Hayashi, K., Komura, S., Ohishi, N., and Yagi, K. (1999). Loss of molecular interaction between cytochrome c and cardiolipin due to lipid peroxidation. Biochem. Biophys. Res. Commun. 264, 343-347.
    • (1999) Biochem. Biophys. Res. Commun. , vol.264 , pp. 343-347
    • Shidoji, Y.1    Hayashi, K.2    Komura, S.3    Ohishi, N.4    Yagi, K.5
  • 285
    • 52449116862 scopus 로고    scopus 로고
    • Uncovering the role of VDAC in the regulation of cell life and death
    • Shoshan-Barmatz, V., Keinan, N., and Zaid, H. (2008). Uncovering the role of VDAC in the regulation of cell life and death. J. Bioenerg. Biomembr.40, 183-191.
    • (2008) J. Bioenerg. Biomembr , vol.40 , pp. 183-191
    • Shoshan-Barmatz, V.1    Keinan, N.2    Zaid, H.3
  • 286
    • 0032701640 scopus 로고    scopus 로고
    • 2+ signals in oligodendrocyte progenitors
    • 2+ signals in oligodendrocyte progenitors. Cell Calcium 26, 121-130.
    • (1999) Cell Calcium , vol.26 , pp. 121-130
    • Smaili, S.S.1    Russell, J.T.2
  • 290
    • 25144478337 scopus 로고    scopus 로고
    • Biochemical dysfunction in heart mitochondria exposed to ischaemia and reperfusion
    • Solaini, G., and Harris, D. A. (2005). Biochemical dysfunction in heart mitochondria exposed to ischaemia and reperfusion. Biochem. J. 390(Pt 2), 377-394.
    • (2005) Biochem. J. , vol.390 , Issue.PART 2 , pp. 377-394
    • Solaini, G.1    Harris, D.A.2
  • 292
    • 0342506484 scopus 로고    scopus 로고
    • Regulation of energy substrate metabolism in the diabetic heart
    • Stanley, W. C., Lopaschuk, G. D., and McCormack, J. G. (1997). Regulation of energy substrate metabolism in the diabetic heart. Cardiovasc. Res. 34, 25-33.
    • (1997) Cardiovasc. Res. , vol.34 , pp. 25-33
    • Stanley, W.C.1    Lopaschuk, G.D.2    McCormack, J.G.3
  • 293
    • 21244492310 scopus 로고    scopus 로고
    • Myocardial substrate metabolism in the normal and failing heart
    • Stanley, W. C., Recchia, F. A., and Lopaschuk, G. D. (2005). Myocardial substrate metabolism in the normal and failing heart. Physiol. Rev. 85, 1093-1129.
    • (2005) Physiol. Rev. , vol.85 , pp. 1093-1129
    • Stanley, W.C.1    Recchia, F.A.2    Lopaschuk, G.D.3
  • 296
    • 65349123514 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species production in excitable cells: modulators of mitochondrial and cell function Antioxid
    • [Comprehensive review]
    • Stowe, D. F., and Camara, A. K. S. (2009). Mitochondrial reactive oxygen species production in excitable cells: modulators of mitochondrial and cell function Antioxid. Redox Signal. 11, 1373-1396. [Comprehensive review].
    • (2009) Redox Signal , vol.11 , pp. 1373-1396
    • Stowe, D.F.1    Camara, A.K.S.2
  • 300
    • 34547673497 scopus 로고    scopus 로고
    • Peroxynitrite: biochemistry, pathophysiology and development of therapeutics
    • Szabo, C., Ischiropoulos, H., and Radi, R. (2007). Peroxynitrite: biochemistry, pathophysiology and development of therapeutics. Nat. Rev. Drug Discov. 6, 662-680.
    • (2007) Nat. Rev. Drug Discov. , vol.6 , pp. 662-680
    • Szabo, C.1    Ischiropoulos, H.2    Radi, R.3
  • 302
    • 0034733585 scopus 로고    scopus 로고
    • Dose-dependent effect of resveratrol on proliferation and apoptosis in endothelial and tumor cell cultures
    • Szende, B., Tyihak, E., and Kiraly-Veghely, Z. (2000). Dose-dependent effect of resveratrol on proliferation and apoptosis in endothelial and tumor cell cultures. Exp. Mol. Med. 32, 88-92.
    • (2000) Exp. Mol. Med. , vol.32 , pp. 88-92
    • Szende, B.1    Tyihak, E.2    Kiraly-Veghely, Z.3
  • 303
    • 57649187112 scopus 로고    scopus 로고
    • Development of mitochondria-targeted aromatic-cationic peptides for neurodegenerative diseases
    • Szeto, H. H. (2008a). Development of mitochondria-targeted aromatic-cationic peptides for neurodegenerative diseases. Ann. N. Y. Acad. Sci. 1147, 112-121.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1147 , pp. 112-121
    • Szeto, H.H.1
  • 304
    • 38349010993 scopus 로고    scopus 로고
    • Mitochondria-targeted cytoprotective peptides for ischemia-reperfusion injury
    • Szeto, H. H. (2008b). Mitochondria-targeted cytoprotective peptides for ischemia-reperfusion injury. Antioxid. Redox Signal. 10, 601-619.
    • (2008) Antioxid. Redox Signal. , vol.10 , pp. 601-619
    • Szeto, H.H.1
  • 307
    • 34249689057 scopus 로고    scopus 로고
    • Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission
    • Taguchi, N., Ishihara, N., Jofuku, A., Oka, T., and Mihara, K. (2007). Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission. J. Biol. Chem. 282, 11521-11529.
    • (2007) J. Biol. Chem. , vol.282 , pp. 11521-11529
    • Taguchi, N.1    Ishihara, N.2    Jofuku, A.3    Oka, T.4    Mihara, K.5
  • 308
    • 0141918797 scopus 로고    scopus 로고
    • Nicorandil prevents oxidative stress-induced apoptosis in neurons by activating mitochondrial ATP-sensitive potassium channels
    • Teshima, Y., Akao, M., Baumgartner, W. A., and Marban, E. (2003a). Nicorandil prevents oxidative stress-induced apoptosis in neurons by activating mitochondrial ATP-sensitive potassium channels. Brain Res. 990, 45-50.
    • (2003) Brain Res , vol.990 , pp. 45-50
    • Teshima, Y.1    Akao, M.2    Baumgartner, W.A.3    Marban, E.4
  • 309
    • 0042526012 scopus 로고    scopus 로고
    • Uncoupling protein-2 overexpression inhibits mitochondrial death pathway in cardiomyocytes
    • Teshima, Y., Akao, M., Jones, S. P., and Marban, E. (2003b). Uncoupling protein-2 overexpression inhibits mitochondrial death pathway in cardiomyocytes. Circ. Res. 93, 192-200.
    • (2003) Circ. Res. , vol.93 , pp. 192-200
    • Teshima, Y.1    Akao, M.2    Jones, S.P.3    Marban, E.4
  • 310
    • 38649116627 scopus 로고    scopus 로고
    • Minocycline and N-methyl-4-isoleucine cyclosporin (NIM811) mitigate storage/reperfusion injury after rat liver transplantation through suppression of the mitochondrial permeability transition
    • Theruvath, T. P., Zhong, Z., Pediaditakis, P., Ramshesh, V. K., Currin, R. T., Tikunov, A., Holmuhamedov, E., and Lemasters, J. J. (2008). Minocycline and N-methyl-4-isoleucine cyclosporin (NIM811) mitigate storage/reperfusion injury after rat liver transplantation through suppression of the mitochondrial permeability transition. Hepatology 47, 236-246.
    • (2008) Hepatology , vol.47 , pp. 236-246
    • Theruvath, T.P.1    Zhong, Z.2    Pediaditakis, P.3    Ramshesh, V.K.4    Currin, R.T.5    Tikunov, A.6    Holmuhamedov, E.7    Lemasters, J.J.8
  • 311
    • 33845979877 scopus 로고    scopus 로고
    • Mitochondrial targeting with antioxidant peptide SS-31 prevents mitochondrial depolarization, reduces islet cell apoptosis, increases islet cell yield, and improves posttransplantation function
    • Thomas, D. A., Stauffer, C., Zhao, K., Yang, H., Sharma, V. K., Szeto, H. H., and Suthanthiran, M. (2007). Mitochondrial targeting with antioxidant peptide SS-31 prevents mitochondrial depolarization, reduces islet cell apoptosis, increases islet cell yield, and improves posttransplantation function. J. Am. Soc. Nephrol. 18, 213-222.
    • (2007) J. Am. Soc. Nephrol. , vol.18 , pp. 213-222
    • Thomas, D.A.1    Stauffer, C.2    Zhao, K.3    Yang, H.4    Sharma, V.K.5    Szeto, H.H.6    Suthanthiran, M.7
  • 313
    • 33750915424 scopus 로고    scopus 로고
    • Mitochondrial oxidative stress, DNA damage, and heart failure
    • Tsutsui, H., Ide, T., and Kinugawa, S. (2006). Mitochondrial oxidative stress, DNA damage, and heart failure. Antioxid. Redox Signal. 8, 1737-1744.
    • (2006) Antioxid. Redox Signal. , vol.8 , pp. 1737-1744
    • Tsutsui, H.1    Ide, T.2    Kinugawa, S.3
  • 314
    • 33748040754 scopus 로고    scopus 로고
    • Modulations of VEGF and iNOS in the rat heart by low level laser therapy are associated with cardioprotection and enhanced angiogenesis
    • Tuby, H., Maltz, L., and Oron, U. (2006). Modulations of VEGF and iNOS in the rat heart by low level laser therapy are associated with cardioprotection and enhanced angiogenesis. Lasers Surg. Med. 38, 682-688.
    • (2006) Lasers Surg. Med. , vol.38 , pp. 682-688
    • Tuby, H.1    Maltz, L.2    Oron, U.3
  • 315
    • 0021996572 scopus 로고
    • Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria
    • Turrens, J. F., Alexandre, A., and Lehninger, A. L. (1985). Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria. Arch. Biochem. Biophys. 237, 408-414.
    • (1985) Arch. Biochem. Biophys. , vol.237 , pp. 408-414
    • Turrens, J.F.1    Alexandre, A.2    Lehninger, A.L.3
  • 316
    • 0019083215 scopus 로고
    • Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria
    • Turrens, J. F., and Boveris, A. (1980). Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria. Biochem. J. 191, 421-427.
    • (1980) Biochem. J. , vol.191 , pp. 421-427
    • Turrens, J.F.1    Boveris, A.2
  • 318
    • 33749453003 scopus 로고    scopus 로고
    • Decreased myocardial free fatty acid uptake in patients with idiopathic dilated cardiomyopathy: evidence of relationship with insulin resistance and left ventricular dysfunction
    • Tuunanen, H., Engblom, E., Naum, A., Scheinin, M., Nagren, K., Airaksinen, J., Nuutila, P., Iozzo, P., Ukkonen, H., and Knuuti, J. (2006b). Decreased myocardial free fatty acid uptake in patients with idiopathic dilated cardiomyopathy: evidence of relationship with insulin resistance and left ventricular dysfunction. J. Card. Fail. 12, 644-652.
    • (2006) J. Card. Fail. , vol.12 , pp. 644-652
    • Tuunanen, H.1    Engblom, E.2    Naum, A.3    Scheinin, M.4    Nagren, K.5    Airaksinen, J.6    Nuutila, P.7    Iozzo, P.8    Ukkonen, H.9    Knuuti, J.10
  • 319
    • 0032534748 scopus 로고    scopus 로고
    • Redox regulation of caspase-3(-like) protease activity: regulatory roles of thioredoxin and cytochrome c
    • Ueda, S., Nakamura, H., Masutani, H., Sasada, T., Yonehara, S., Takabayashi, A., Yamaoka, Y., and Yodoi, J. (1998). Redox regulation of caspase-3(-like) protease activity: regulatory roles of thioredoxin and cytochrome c. J. Immunol. 161, 6689-6695.
    • (1998) J. Immunol. , vol.161 , pp. 6689-6695
    • Ueda, S.1    Nakamura, H.2    Masutani, H.3    Sasada, T.4    Yonehara, S.5    Takabayashi, A.6    Yamaoka, Y.7    Yodoi, J.8
  • 321
    • 0031239737 scopus 로고    scopus 로고
    • Significant levels of oxidants are generated by isolated cardiomyocytes during ischemia prior to reperfusion
    • Vanden Hoek, T. L., Li, C., Shao, Z., Schumacker, P. T., and Becker, L. B. (1997). Significant levels of oxidants are generated by isolated cardiomyocytes during ischemia prior to reperfusion. J. Mol. Cell. Cardiol. 29, 2571-2583.
    • (1997) J. Mol. Cell. Cardiol. , vol.29 , pp. 2571-2583
    • Vanden Hoek, T.L.1    Li, C.2    Shao, Z.3    Schumacker, P.T.4    Becker, L.B.5
  • 323
    • 0032557204 scopus 로고    scopus 로고
    • Variations in the subunit content and catalytic activity of the cytochrome c oxidase complex from different tissues and different cardiac compartments
    • Vijayasarathy, C., Biunno, I., Lenka, N., Yang, M., Basu, A., Hall, I. P., and Avadhani, N. G. (1998). Variations in the subunit content and catalytic activity of the cytochrome c oxidase complex from different tissues and different cardiac compartments. Biochim. Biophys. Acta 1371, 71-82.
    • (1998) Biochim. Biophys. Acta , vol.1371 , pp. 71-82
    • Vijayasarathy, C.1    Biunno, I.2    Lenka, N.3    Yang, M.4    Basu, A.5    Hall, I.P.6    Avadhani, N.G.7
  • 326
    • 0026585611 scopus 로고
    • Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the 'phosphocreatine circuit' for cellular energy homeostasis
    • Wallimann, T., Wyss, M., Brdiczka, D., Nicolay, K., and Eppenberger, H. M. (1992). Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the 'phosphocreatine circuit' for cellular energy homeostasis. Biochem. J. 281(Pt 1), 21-40.
    • (1992) Biochem. J. , vol.281 , Issue.PART 1 , pp. 21-40
    • Wallimann, T.1    Wyss, M.2    Brdiczka, D.3    Nicolay, K.4    Eppenberger, H.M.5
  • 329
    • 58949099388 scopus 로고    scopus 로고
    • Effects of overexpression of huntingtin proteins on mitochondrial integrity
    • Wang, H., Lim, P. J., Karbowski, M., and Monteiro, M. J. (2009). Effects of overexpression of huntingtin proteins on mitochondrial integrity. Hum. Mol. Genet. 18, 737-752.
    • (2009) Hum. Mol. Genet. , vol.18 , pp. 737-752
    • Wang, H.1    Lim, P.J.2    Karbowski, M.3    Monteiro, M.J.4
  • 330
    • 1342316811 scopus 로고    scopus 로고
    • Protective effect of the SOD/catalase mimetic MnTMPyP on inflammation-mediated dopaminergic neurodegeneration in mesencephalic neuronal-glial cultures
    • Wang, T., Liu, B., Qin, L., Wilson, B., and Hong, J. S. (2004). Protective effect of the SOD/catalase mimetic MnTMPyP on inflammation-mediated dopaminergic neurodegeneration in mesencephalic neuronal-glial cultures. J. Neuroimmunol. 147, 68-72.
    • (2004) J. Neuroimmunol. , vol.147 , pp. 68-72
    • Wang, T.1    Liu, B.2    Qin, L.3    Wilson, B.4    Hong, J.S.5
  • 331
    • 0037131391 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species trigger calcium increases during hypoxia in pulmonary arterial myocytes
    • Waypa, G. B., Marks, J. D., Mack, M. M., Boriboun, C., Mungai, P. T., and Schumacker, P. T. (2002). Mitochondrial reactive oxygen species trigger calcium increases during hypoxia in pulmonary arterial myocytes. Circ. Res. 91, 719-726.
    • (2002) Circ. Res. , vol.91 , pp. 719-726
    • Waypa, G.B.1    Marks, J.D.2    Mack, M.M.3    Boriboun, C.4    Mungai, P.T.5    Schumacker, P.T.6
  • 333
    • 0017829082 scopus 로고
    • Control of fatty acid metabolism in ischemic and hypoxic hearts
    • Whitmer, J. T., Idell-Wenger, J. A., Rovetto, M. J., and Neely, J. R. (1978). Control of fatty acid metabolism in ischemic and hypoxic hearts. J. Biol. Chem. 253, 4305-4309.
    • (1978) J. Biol. Chem. , vol.253 , pp. 4305-4309
    • Whitmer, J.T.1    Idell-Wenger, J.A.2    Rovetto, M.J.3    Neely, J.R.4
  • 335
    • 0000430925 scopus 로고
    • Glycolytic control mechanisms. I. Inhibition of glycolysis by acetate and pyruvate in the isolated, perfused rat heart
    • Williamson, J. R. (1965). Glycolytic control mechanisms. I. Inhibition of glycolysis by acetate and pyruvate in the isolated, perfused rat heart. J. Biol. Chem. 240, 2308-2321.
    • (1965) J. Biol. Chem. , vol.240 , pp. 2308-2321
    • Williamson, J.R.1
  • 336
    • 0014011501 scopus 로고
    • Glycolytic control mechanism II.s Kinetics of intermediate changes during the aerobic-anoxic transition in perfused rat heart
    • Williamson, J. R. (1966). Glycolytic control mechanisms. II. Kinetics of intermediate changes during the aerobic-anoxic transition in perfused rat heart. J. Biol. Chem. 241, 5026-5036.
    • (1966) J. Biol. Chem. , vol.241 , pp. 5026-5036
    • Williamson, J.R.1
  • 337
    • 0018336297 scopus 로고
    • Mitochondrial function in the heart
    • Williamson, J. R. (1979). Mitochondrial function in the heart. Annu. Rev. Physiol. 41, 485-506.
    • (1979) Annu. Rev. Physiol. , vol.41 , pp. 485-506
    • Williamson, J.R.1
  • 338
    • 0017071201 scopus 로고
    • Coordination of citric acid cycle activity with electron transport flux
    • Williamson, J. R., Ford, C., Illingworth, J., and Safer, B. (1976). Coordination of citric acid cycle activity with electron transport flux. Circ. Res. 38(Suppl. 1), I39-I51.
    • (1976) Circ. Res. , vol.38 , Issue.SUPPL. 1
    • Williamson, J.R.1    Ford, C.2    Illingworth, J.3    Safer, B.4
  • 339
    • 55249094825 scopus 로고    scopus 로고
    • Mitochondria in cell life, death and disease
    • Wojtczak, L., and Zablocki, K. (2008). Mitochondria in cell life, death and disease. Postepy Biochem. 54, 129-141.
    • (2008) Postepy Biochem , vol.54 , pp. 129-141
    • Wojtczak, L.1    Zablocki, K.2
  • 340
    • 62249098383 scopus 로고    scopus 로고
    • The complex II inhibitor atpenin A5 protects against cardiac ischemia-reperfusion injury via activation of mitochondrial KATP channels
    • Wojtovich, A. P., and Brookes, P. S. (2009). The complex II inhibitor atpenin A5 protects against cardiac ischemia-reperfusion injury via activation of mitochondrial KATP channels. Basic Res. Cardiol. 104, 121-129.
    • (2009) Basic Res. Cardiol. , vol.104 , pp. 121-129
    • Wojtovich, A.P.1    Brookes, P.S.2
  • 341
    • 0027008279 scopus 로고
    • Possible new therapeutic approach in diabetes mellitus by inhibition of carnitine palmitoyltransferase 1 (CPT1)
    • Wolf, H. P. (1992). Possible new therapeutic approach in diabetes mellitus by inhibition of carnitine palmitoyltransferase 1 (CPT1). Horm. Metab. Res. Suppl. 26, 62-67.
    • (1992) Horm. Metab. Res , Issue.SUPPL. , pp. 62-67
    • Wolf, H.P.1
  • 342
    • 14244261143 scopus 로고    scopus 로고
    • Photobiomodulation directly benefits primary neurons functionally inactivated by toxins: role of cytochrome c oxidase
    • Wong-Riley, M. T., Liang, H. L., Eells, J. T., Chance, B., Henry, M. M., Buchmann, E., Kane, M., and Whelan, H. T. (2005). Photobiomodulation directly benefits primary neurons functionally inactivated by toxins: role of cytochrome c oxidase. J. Biol. Chem. 280, 4761-4771.
    • (2005) J. Biol. Chem. , vol.280 , pp. 4761-4771
    • Wong-Riley, M.T.1    Liang, H.L.2    Eells, J.T.3    Chance, B.4    Henry, M.M.5    Buchmann, E.6    Kane, M.7    Whelan, H.T.8
  • 343
    • 34250001447 scopus 로고    scopus 로고
    • The hydrogen highway to reperfusion therapy
    • Wood, K. C., and Gladwin, M. T. (2007). The hydrogen highway to reperfusion therapy. Nat. Med. 13, 673-674.
    • (2007) Nat. Med. , vol.13 , pp. 673-674
    • Wood, K.C.1    Gladwin, M.T.2
  • 344
    • 34548297895 scopus 로고    scopus 로고
    • Computer modeling of mitochondrial tricarboxylic acid cycle, oxidative phosphorylation, metabolite transport, and electrophysiology
    • Wu, F., Yang, F., Vinnakota, K. C., and Beard, D. A. (2007). Computer modeling of mitochondrial tricarboxylic acid cycle, oxidative phosphorylation, metabolite transport, and electrophysiology. J. Biol. Chem. 282, 24525-24537.
    • (2007) J. Biol. Chem. , vol.282 , pp. 24525-24537
    • Wu, F.1    Yang, F.2    Vinnakota, K.C.3    Beard, D.A.4
  • 345
    • 51749122229 scopus 로고    scopus 로고
    • Phosphate metabolite concentrations and ATP hydrolysis potential in normal and ischaemic hearts
    • Wu, F., Zhang, E. Y., Zhang, J., Bache, R. J., and Beard, D. A. (2008). Phosphate metabolite concentrations and ATP hydrolysis potential in normal and ischaemic hearts. J. Physiol. 586(Pt 17), 4193-4208.
    • (2008) J. Physiol. , vol.586 , Issue.PART 17 , pp. 4193-4208
    • Wu, F.1    Zhang, E.Y.2    Zhang, J.3    Bache, R.J.4    Beard, D.A.5
  • 346
    • 0028841015 scopus 로고
    • The antianginal agent ranolazine is a weak inhibitor of the respiratory complex I, but with greater potency in broken or uncoupled than in coupled mitochondria
    • Wyatt, K. M., Skene, C., Veitch, K., Hue, L., and McCormack, J. G. (1995). The antianginal agent ranolazine is a weak inhibitor of the respiratory complex I, but with greater potency in broken or uncoupled than in coupled mitochondria. Biochem. Pharmacol. 50, 1599-1606.
    • (1995) Biochem. Pharmacol. , vol.50 , pp. 1599-1606
    • Wyatt, K.M.1    Skene, C.2    Veitch, K.3    Hue, L.4    McCormack, J.G.5
  • 348
    • 46749156297 scopus 로고    scopus 로고
    • Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species
    • Yu, T., Sheu, S. S., Robotham, J. L., and Yoon, Y. (2008). Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species. Cardiovasc. Res. 79, 341-351.
    • (2008) Cardiovasc. Res. , vol.79 , pp. 341-351
    • Yu, T.1    Sheu, S.S.2    Robotham, J.L.3    Yoon, Y.4
  • 354
    • 34547850680 scopus 로고    scopus 로고
    • Succinate modulation of H2O2 release at NADH:ubiquinone oxidoreductase (Complex I) in brain mitochondria
    • Zoccarato, F., Cavallini, L., Bortolami, S., and Alexandre, A. (2007). Succinate modulation of H2O2 release at NADH:ubiquinone oxidoreductase (Complex I) in brain mitochondria. Biochem. J. 406, 125-129.
    • (2007) Biochem. J. , vol.406 , pp. 125-129
    • Zoccarato, F.1    Cavallini, L.2    Bortolami, S.3    Alexandre, A.4
  • 355
    • 0034596947 scopus 로고    scopus 로고
    • Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes
    • Zorov, D. B., Filburn, C. R., Klotz, L. O., Zweier, J. L., and Sollott, S. J. (2000). Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes. J. Exp. Med. 192, 1001-1014.
    • (2000) J. Exp. Med. , vol.192 , pp. 1001-1014
    • Zorov, D.B.1    Filburn, C.R.2    Klotz, L.O.3    Zweier, J.L.4    Sollott, S.J.5
  • 356
    • 4043052144 scopus 로고    scopus 로고
    • Examining intracellular organelle function using fluorescent probes: from animalcules to quantum dots
    • Zorov, D. B., Kobrinsky, E., Juhaszova, M., and Sollott, S. J. (2004). Examining intracellular organelle function using fluorescent probes: from animalcules to quantum dots. Circ. Res. 95, 239-252.
    • (2004) Circ. Res. , vol.95 , pp. 239-252
    • Zorov, D.B.1    Kobrinsky, E.2    Juhaszova, M.3    Sollott, S.J.4
  • 357
    • 33947628672 scopus 로고    scopus 로고
    • Carbon monoxide signals via inhibition of cytochrome c oxidase and generation of mitochondrial reactive oxygen species
    • Zuckerbraun, B. S., Chin, B. Y., Bilban, M., d'Avila, J. C., Rao, J., Billiar, T. R., and Otterbein, L. E. (2007). Carbon monoxide signals via inhibition of cytochrome c oxidase and generation of mitochondrial reactive oxygen species. FASEB J. 21, 1099-1106.
    • (2007) FASEB J , vol.21 , pp. 1099-1106
    • Zuckerbraun, B.S.1    Chin, B.Y.2    Bilban, M.3    d'Avila, J.C.4    Rao, J.5    Billiar, T.R.6    Otterbein, L.E.7
  • 358
    • 67650671552 scopus 로고    scopus 로고
    • Mitochondrial hexokinase and cardioprotection of the intact heart
    • Zuurbier, C. J., Smeele, K. M., and Eerbeek, O. (2009). Mitochondrial hexokinase and cardioprotection of the intact heart. J. Bioenerg. Biomembr. 41, 181-185.
    • (2009) J. Bioenerg. Biomembr. , vol.41 , pp. 181-185
    • Zuurbier, C.J.1    Smeele, K.M.2    Eerbeek, O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.