Succinate modulation of H2O2 release at NADH:ubiquinone oxidoreductase (Complex I) in brain mitochondria

Biochemical Journal

Volumn 406, Issue 1, 2007, Pages 125-129

  Zoccarato, Franco ^a   Cavallini, Lucia ^a   Bortolami, Silvia ^a   Alexandre, Adolfo ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

Brain mitochondrion; Electron transfer; Hydrogen peroxide production; NADH:ubiquinone oxidoreductase (Complex I); Reactive oxygen species; Succinate

Indexed keywords

BRAIN; CELLS; ELECTRON TRANSITIONS; HYDROGEN PEROXIDE; OXIDATION;

BRAIN MITOCHONDRION; ELECTRON FLOW; ROTENONE;

ENZYMES;

2 OXOGLUTARIC ACID; GLUTAMIC ACID; HYDROGEN PEROXIDE; MALIC ACID; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); ROTENONE; SUCCINIC ACID; ALPHA-KETOGLUTARIC ACID; MALIC ACID DERIVATIVE; SUCCINIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BRAIN MITOCHONDRION; CONTROLLED STUDY; ENZYME RELEASE; NONHUMAN; OXIDATION; OXYGEN CONSUMPTION; PH MEASUREMENT; PRIORITY JOURNAL; RAT; ANIMAL; DRUG EFFECT; ELECTRON TRANSPORT; ENZYME SPECIFICITY; ENZYMOLOGY; METABOLISM; MITOCHONDRION; OXIDATION REDUCTION REACTION; PH; TITRIMETRY;

ANIMALS; ELECTRON TRANSPORT; ELECTRON TRANSPORT COMPLEX I; GLUTAMIC ACID; HYDROGEN PEROXIDE; HYDROGEN-ION CONCENTRATION; KETOGLUTARIC ACIDS; MALATES; MITOCHONDRIA; OXIDATION-REDUCTION; OXYGEN CONSUMPTION; RATS; SUBSTRATE SPECIFICITY; SUCCINATES; TITRIMETRY;

EID: 34547850680     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20070215     Document Type: Article

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