A peptide trivalent arsenical inhibits tumor angiogenesis by perturbing mitochondrial function in angiogenic endothelial cells

Cancer Cell

Volumn 3, Issue 5, 2003, Pages 497-509

  Don, Anthony S ^a   Kisker, Oliver ^b   Dilda, Pierre ^a   Donoghue, Neil ^a   Zhao, Xueyun ^a   Decollogne, Stephanie ^a   Creighton, Belinda ^a   Flynn, Evelyn ^b   Folkman, Judah ^b   Hogg, Philip J ^a,b  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 [N (S GLUTATHIONYLACETYL)AMINO]PHENYLARSENOXIDE; ADENINE NUCLEOTIDE TRANSLOCASE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; CALCIUM ION; CYSTEINE; ORGANOARSENIC DERIVATIVE; PEPTIDE DERIVATIVE; SUPEROXIDE; UNCLASSIFIED DRUG; ARSENOSOBENZENE; BIOTIN; CALCIUM; CARRIER PROTEIN; DRUG DERIVATIVE; ENZYME INHIBITOR; EOSIN; EOSIN MALEIMIDE; ION CHANNEL; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; PEPTIDE;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL GROWTH; CELL PROLIFERATION; CHICKEN; CHORIOALLANTOIS; CONCENTRATION RESPONSE; CROSS LINKING; CYTOSOL; EMBRYO; ENDOTHELIUM CELL; ENZYME INACTIVATION; EXTRACELLULAR MATRIX; FEMALE; HUMAN; HUMAN CELL; MALE; MEMBRANE DEPOLARIZATION; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL PERMEABILITY; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SOLID TUMOR; TUMOR VASCULARIZATION; ANIMAL; AORTA; BAGG ALBINO MOUSE; C57BL MOUSE; CATTLE; CELL DIVISION; CELL SURVIVAL; CHEMICAL MODEL; CHEMISTRY; CHICK EMBRYO; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; FLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; METABOLISM; MOUSE MUTANT; NEOVASCULARIZATION (PATHOLOGY); TIME;

ANIMALIA; FORMICIDAE; GALLUS GALLUS;

ADENINE NUCLEOTIDE TRANSLOCATOR 1; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANGIOGENESIS INHIBITORS; ANIMALS; AORTA; APOPTOSIS; ARSENICALS; BIOTIN; CALCIUM; CATTLE; CELL DIVISION; CELL SURVIVAL; CHICK EMBRYO; CYTOSOL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; ENZYME INHIBITORS; EOSINE YELLOWISH-(YS); FEMALE; IMMUNOHISTOCHEMISTRY; ION CHANNELS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, SCID; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MODELS, CHEMICAL; NEOVASCULARIZATION, PATHOLOGIC; PEPTIDES; TIME FACTORS;

EID: 0142010897     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1535-6108(03)00109-0     Document Type: Article

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