Modeling of oxygen transport and cellular energetics explains observations on in vivo cardiac energy metabolism

PLoS Computational Biology

Volumn 2, Issue 9, 2006, Pages 1093-1106

  Beard, Daniel A ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; BIOMOLECULES; CYTOLOGY; HEART; METABOLISM; METABOLITES; OXYGEN; PHOSPHATES; TISSUE;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ENERGY; ENERGY METABOLISM; HYPOPERFUSION; IN-VIVO; INORGANIC PHOSPHATES; INTEGRATED MODELING; OXYGEN TRANSPORT; PHOSPHATE LEVELS;

MITOCHONDRIA;

ADENOSINE TRIPHOSPHATE; ADENYLATE KINASE; CARRIER PROTEIN; CREATINE KINASE; NUCLEOTIDE; PHOSPHATE TRANSPORTER; MYOGLOBIN; OXYGEN; PHOSPHATE;

ARTICLE; CAPILLARY; CELL ENERGY; CELL ISOLATION; CORONARY ARTERY BLOOD FLOW; CYTOPLASM; ENERGY METABOLISM; GENETIC REGULATION; HEART MUSCLE METABOLISM; IN VIVO STUDY; INTERSTITIAL FLUID; LABORATORY; MATHEMATICAL ANALYSIS; MITOCHONDRIAL RESPIRATION; OBSERVATIONAL STUDY; OXYGEN CONSUMPTION; OXYGEN TRANSPORT; PROTEIN PHOSPHORYLATION; TISSUE OXYGENATION; WORKLOAD; BIOLOGICAL MODEL; BIOLOGY; COMPUTER SIMULATION; CYTOSOL; HEART MUSCLE; METABOLISM; MITOCHONDRION; TRANSPORT AT THE CELLULAR LEVEL;

ADENOSINE TRIPHOSPHATE; BIOLOGICAL TRANSPORT; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; CYTOSOL; ENERGY METABOLISM; MITOCHONDRIA; MODELS, BIOLOGICAL; MYOCARDIUM; MYOGLOBIN; OXYGEN; PHOSPHATES;

EID: 33749339635     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.0020107     Document Type: Article

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