Opening of the Mitochondrial Permeability Transition Pore Causes Depletion of Mitochondrial and Cytosolic NAD+ and Is a Causative Event in the Death of Myocytes in Postischemic Reperfusion of the Heart

Journal of Biological Chemistry

Volumn 276, Issue 4, 2001, Pages 2571-2575

  Di Lisa, Fabio ^a   Menabò, Roberta ^a   Canton, Marcella ^a   Barile, Maria ^b   Bernardi, Paolo ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF BARI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DEHYDROGENATION; ENZYME KINETICS; HYDROLYSIS; REDUCTION; TISSUE;

PERMEABILITY TRANSITION PORE (PTP); REPERFUSION DAMAGE;

BIOCHEMISTRY;

CALCIUM ION; CYCLOSPORIN A; CYCLOSPORIN DERIVATIVE; LACTATE DEHYDROGENASE; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; N METHYLVALINE 4 CYCLOSPORIN; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE NUCLEOSIDASE; SUBTILISIN; TRITON X 100; UNCLASSIFIED DRUG; VALINE; CARRIER PROTEIN; CYCLOSPORIN; ION CHANNEL; MEMBRANE PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; ENZYME REGULATION; HEART MITOCHONDRION; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; HYDROLYSIS; ISOLATED HEART; MALE; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; SARCOLEMMA; ANIMAL; HEART MUSCLE; IN VITRO STUDY; METABOLISM; PATHOLOGY; WISTAR RAT;

ANIMALIA;

ANIMALS; CELL DEATH; CYCLOSPORINE; CYTOSOL; ION CHANNELS; MALE; MEMBRANE PROTEINS; MITOCHONDRIA, HEART; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NAD; NAD+ NUCLEOSIDASE; RATS; RATS, WISTAR;

EID: 0035951823     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M006825200     Document Type: Article

References (48)

1. Jennings, R. B., and Reimer, K. A. (1991) Annu. Rev. Med. 42, 225-246
2. Silverman, H. S., and Stern, M. D. (1994) Cardiovasc. Res. 28, 581-597
3. Di Lisa, F., Menabò, R., Canton, M., and Petronilli, V. (1998) Biochim. Biophys. Acta 1366, 69-78
4. Di Lisa, F., Blank, P. S., Colonna, R., Gambassi, G., Silverman, H. S., Stern, M. D., and Hansford, R. G. (1995) J. Physiol. (Lond.) 486, 1-13
5. Ganote, C. E., Worstell, J., and Kaltenbach, J. P. (1976) Am. J. Pathol. 84, 327-350
6. Ganote, C. E., McGarr, J., Liu, S. Y., and Kaltenbach, J. P. (1980) J. Mol. Cell. Cardiol. 12, 387-408
7. Miyata, H., Lakatta, E. G., Stern, M. D., and Silverman, H. S. (1992) Circ. Res. 71, 605-613
8. Ganote, C. E., and Armstrong, S. C. (1993) Cardiovasc. Res. 27, 1387-1403
9. Jennings, R. B., Murry, C. E., Steenbergen, C., and Reimer, K. A. (1990) Circulation 82, 2-12
10. Bernardi, P. (1999) Physiol. Rev. 79, 1127-1155
11. Bernardi, P., Broekemeier, K. M., and Pfeiffer, D. R. (1994) J. Bioenerg. Biomembr. 26, 509-517
12. Nazareth, W., Yafei, N., and Crompton, M. (1991) J. Mol. Cell. Cardiol. 23, 1351-1354
13. Duchen, M. R., McGuinness, O., Brown, L. A., and Crompton, M. (1993) Cardiovasc. Res. 27, 1790-1794
14. Minezaki, K. K., Suleiman, M. S., and Chapman, R. A. (1994) J. Physiol. (Lond.) 476, 459-471
15. Griffiths, E. J., and Halestrap, A. P. (1993) J. Mol. Cell. Cardiol. 25, 1461-1469
16. Griffiths, E. J., and Halestrap, A. P. (1995) Biochem. J. 307, 93-98
17. Vinogradov, A., Scarpa, A., and Chance, B. (1972) Arch. Biochem. Biophys. 152, 646-654
18. Di Lisa, F., Menabò, R., Barbato, R., and Siliprandi, N. (1994) Am. J. Physiol. 267, H455-H461
19. Lindenmayer, G. E., Sordahl, L. A., and Schwartz, A. (1968) Circ. Res. 23, 439-450
20. Di Lisa, F., Fan, C. Z., Gambassi, G., Hogue, B. A., Kudryashova, I., and Hansford, R. G. (1993) Am. J. Physiol. 264, H2188-H2197
21. Scorrano, L., Petronilli, V., Di Lisa, F., and Bernardi, P. (1999) J. Biol. Chem. 274, 22581-22585
22. Klingenberg, M. (1985) in Methods of Enzymatic Analysis (Bergmeyer, H. U., ed) pp. 251-271, Verlag Chemie, Weinheim, Germany
23. Veloso, D., and Veech, R. L. (1974) Anal. Biochem. 62, 449-450
24. Barile, M., Brizio, C., De Virgilio, C., Delfine, S., Quagliariello, E., and Passarella, S. (1997) Eur. J. Biochem. 249, 777-785
25. Barrio, J. R., Secrist, J. A., and Leonard, N. J. (1972) Proc. Natl. Acad. Sci. U. S. A. 69, 2039-2042
26. Bergmeyer, H. U., and Bernt, E. (1974) in Methods of Enzymatic Analysis (Bergmeyer, H. U., ed) pp. 607-612, Verlag Chemie, Weinheim, Germany
27. Barile, M., Passarella, S., Danese, G., and Quagliariello, E. (1996) Biochem. Mol. Biol. Int. 38, 297-306
28. Idell Wenger, J. A., Grotyohann, L. W., and Neely, J. R. (1978) J. Biol. Chem. 253, 4310-4318
29. Palmer, J. W., Tandler, B., and Hoppel, C. L. (1977) J. Biol. Chem. 252, 8731-8739
30. Zimmerman, A. N., and Hülsmann, W. C. (1966) Nature 211, 646-647
31. Boyer, C. S., Moore, G. A., and Moldeus, P. (1993) J. Biol. Chem. 268, 4016-4020
32. Lotscher, H. R., Winterhalter, K. H., Carafoli, E., and Richter, C. (1980) J. Biol. Chem. 255, 9325-9330
33. Richter, C., Winterhalter, K. H., Baumhuter, S., Lotscher, H. R., and Moser, B. (1983) Proc. Natl. Acad. Sci. U. S. A. 80, 3188-3192
34. Frei, B., Winterhalter, K. H., and Richter, C. (1985) Eur. J. Biochem. 149, 633-639
35. Richter, C., Theus, M., and Schlegel, J. (1990) Biochem. Pharmacol. 40, 779-782
36. Shen, A. C., and Jennings, R. B. (1972) Am. J. Pathol. 67, 417-421
37. Nishinaka, Y., Sugiyama, S., Yokota, M., Saito, H., and Ozawa, T. (1993) J. Cardiovasc. Pharmacol. 21, 448-454
38. Morioka, M., Hamada, J., Ushio, Y., and Miyamoto, E. (1999) Prog. Neurobiol. (OXF) 58, 1-30
39. Ruiz, F., Alvarez, G., Ramos, M., Hernandez, M., Bogonez, E., and Satrustegui, J. (2000) Eur. J. Pharmacol. 404, 29-39
40. Zenke, G., Baumann, G., Wenger, R. M., Hiestand, P., Quesniaux, V., Andersen, E., and Schreier, M. H. (1993) Ann. N. Y. Acad. Sci. 685, 330-335
41. Nicolli, A., Basso, E., Petronilli, V., Wenger, R. M., and Bernardi, P. (1996) J. Biol. Chem. 271, 2185-2192
42. Lee, H. C. (1997) Physiol. Rev. 77, 1133-1164
43. Nunez, R., Calva, E., Marsch, M., Briones, E., and Lopez Soriano, F. (1976) Am. J. Physiol. 231, 1173-1177
44. Schaper, J., and Schaper, W. (1983) J. Am. Coll. Cardiol. 1, 1037-1046
45. Thiemermann, C., Bowes, J., Myint, F. P., and Vane, J. R. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 679-683
46. Pieper, A. A., Verma, A., Zhang, J., and Snyder, S. H. (1999) Trends Pharmacol. Sci. 20, 171-181
47. Rustin, P., Parfait, B., Chretien, D., Bourgeron, T., Djouadi, F., Bastin, J., Rotig, A., and Munnich, A. (1996) J. Biol. Chem. 271, 14785-14790
48. Petronilli, V., Miotto, G., Canton, M., Brini, M., Colonna, R., Bernardi, P., and Di Lisa, F. (1999) Biophys. J. 76, 725-734