Cardiac mitochondrial preconditioning by Big Ca 2+-sensitive K + channel opening requires superoxide radical generation

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 290, Issue 1, 2006, Pages

  Stowe, David F ^a,b,c   Aldakkak, Mohammed ^a   Camara, Amadou K S ^a   Riess, Matthias L ^a   Heinen, Andre ^a   Varadarajan, Srinivasan G ^a   Jiang, Ming Tao ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b CLEMENT J ZABLOCKI VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c Medical College of Wisconsin and Marquette University   (United States)

Author keywords

Cell signaling; Energy metabolism; Heart; Ischemic biology; Mitochondria; Oxidant stress; Reactive oxygen species; Redox balance

Indexed keywords

CALCIUM CHANNEL; PAXILLINE; PORPHYRIN; POTASSIUM CHANNEL; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; 1 (2 HYDROXY 5 TRIFLUOROMETHYLPHENYL) 5 TRIFLUOROMETHYL 2(3H) BENZIMIDAZOLONE; BENZIMIDAZOLE DERIVATIVE; CALCIUM; DIAGNOSTIC AGENT; DRUG DERIVATIVE; ETHIDIUM; HYDROETHIDINE; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; NICOTINAMIDE ADENINE DINUCLEOTIDE;

ARTICLE; AUTOFLUORESCENCE; CONTROLLED STUDY; ENERGY METABOLISM; HEART LEFT VENTRICLE PRESSURE; HEART VENTRICLE PRESSURE; ISOLATED HEART; MITOCHONDRION; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SPECTROFLUOROMETRY; ANIMAL; DRUG EFFECT; GUINEA PIG; HEART INFARCTION PREVENTION; HEART MITOCHONDRION; METABOLISM; METHODOLOGY; PHYSIOLOGY;

ANIMALS; BENZIMIDAZOLES; CALCIUM; ETHIDIUM; GUINEA PIGS; ISCHEMIC PRECONDITIONING, MYOCARDIAL; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MITOCHONDRIA, HEART; NAD; REACTIVE OXYGEN SPECIES; SUPEROXIDES;

EID: 33644799324     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00763.2005     Document Type: Article

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