Targeting dinitrophenol to mitochondria: Limitations to the development of a self-limiting mitochondrial protonophore

Bioscience Reports

Volumn 26, Issue 3, 2006, Pages 231-243

  Blaikie, Frances H ^a   Brown, Stephanie E ^b   Samuelsson, Linda M ^a   Brand, Martin D ^b   Smith, Robin A J ^a   Murphy, Michael P ^b  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

Mitochondria; Protonophore; Triphenylphosphonium cation; Uncoupling

Indexed keywords

2,4 DINITROPHENOL; 3 (3,5 DINITRO 4 HYDROXYPHENYL)PROPYLTRIPHENYLPHOSPHONIUM METHANESULFONATE; ADENOSINE TRIPHOSPHATE; FATTY ACID; PHOSPHONIUM DERIVATIVE; TRIPHENYLPHOSPHONIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; LIPOPHILICITY; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; NONHUMAN; OBESITY; OXIDATIVE PHOSPHORYLATION; PROTON MOTIVE FORCE; RAT;

ANIMALS; CELL RESPIRATION; DINITROPHENOLS; IONOPHORES; MEMBRANE POTENTIALS; MITOCHONDRIA, LIVER; MOLECULAR STRUCTURE; PROTONS; RATS; UNCOUPLING AGENTS;

EID: 33747484566     PISSN: 01448463     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10540-006-9018-8     Document Type: Article

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