Evidence for resveratrol-induced preservation of brain mitochondria functions after hypoxia-reoxygenation

Drugs under Experimental and Clinical Research

Volumn 29, Issue 5-6, 2003, Pages 227-233

  Morin, C ^a   Zini, R ^a   Albengres, E ^a   Bertelli, A A E ^b   Bertelli, A ^b   Tillement, J P ^a,c  

^a UNIVERSITÉ PARIS EST CRÉTEIL   (France)

^b UNIVERSITY OF MILAN   (Italy)

^c FACULTÉ DE MÉDECINE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME C; REACTIVE OXYGEN METABOLITE; RESVERATROL; UNCOUPLING PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANOXIA; APOPTOSIS; BRAIN FUNCTION; BRAIN MITOCHONDRION; BRAIN PROTECTION; CELL FUNCTION; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; DOSE RESPONSE; EVIDENCE BASED MEDICINE; HYPOXIA; ISCHEMIA; MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; RAT; REOXYGENATION; REPERFUSION; RESPIRATION CONTROL;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CELL HYPOXIA; CYTOCHROMES C; DOSE-RESPONSE RELATIONSHIP, DRUG; LIPID PEROXIDATION; MEMBRANE FLUIDITY; MITOCHONDRIA; OXYGEN; PROSENCEPHALON; RATS; REACTIVE OXYGEN SPECIES; STILBENES;

EID: 2342596461     PISSN: 03786501     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (11)

1. Steffanelli C., Bonavita F., Stanic I., et al. ATP depletion inhibits glucocorticoid-induced thymocyte apoptosis. Biochem. J., 322, 909, 1997.
2. Soleas G.J., Diamandis E.P., Goldberg D.M. Wine as a biological fluid: History, production, and role in disease prevention. J. Clin. Lab. Anal., 11, 287, 1997.
3. Bhat K.P.L., Kosmeder J.W. II., Pezzuto J.M. Biological effects of resveratrol. Antioxid. Redox Signal, 3, 1041, 2001.
4. Cal C., Garban H., Jazirehi A., Yeh C., Mizutani Y., Bonavida B. Resveratrol and cancer: Chemoprotection, apoptosis, and chemoimmunosensitizing activities. Curr. Med. Chem. Anti-Canc. Agents., 3, 77, 2003.
5. Zini R., Morin C., Bertelli A., Bertelli A.A.E., Tillement J.P. Effects of resveratrol on the rat brain respiratory chain. Drugs Exptl. Clin. Res., 25, 87, 1999.
6. Virgili M., Constestabile A. Partial neuroprotection of in vivo excitotoxic brain damage by chronic administration of the red wine antioxidant agent trans-resveratrol in rats. Neurosci. Lett., 281, 123, 2000.
7. Bertelli A.A.E., Giovannini L., Stradi R., Bertelli A., Tillement J.P. Plasma, urine and tissue levels of trans-resveratrol (3,4′ ,5-trihydroxystilbene) after short-term or prolonged administration of red wine to rats. Int. J. Tissue React., 28, 67, 1996.
8. Zini R., Morin C., Bertelli A., Bertelli A.A.E., Tillement J.P. Resveratrol-induced limitation of dysfunction of mitochondria isolated from rat brain in an anoxia-reoxygenation model. Life Sci., 71, 3091, 2002.
9. Belgendouz L., Fremont L., Gozzelino M.T. Interaction of trans-resveratrol with plasma lipoproteins. Biochem. Pharmacol., 55, 811, 1998.
10. Fauconneau B., Waffo-Teguo P., Huguet F., Barrier L., Decendit A., Merillon J.M. Comparative study of radical scavenger and antioxidant properties of phenolic compounds from Vitis vinifera cell cultures using in vitro tests. Life Sci., 61, 2103, 997.
11. Tadolini B., Juliano C., Piu L., Franconi F., Cabrini L. Resveratrol inhibition of lipid peroxidation. Free Rad. Res., 33, 105, 2000.