Inhibited mitochondrial respiration by amobarbital during cardiac ischaemia improves redox state and reduces matrix Ca2+ overload and ROS release

Cardiovascular Research

Volumn 77, Issue 2, 2008, Pages 406-415

  Aldakkak, Mohammed ^a   Stowe, David F ^a,b,c   Chen, Qun ^d   Lesnefsky, Edward J ^d,e   Camara, Amadou K S ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b CLEMENT J ZABLOCKI VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c Medical College of Wisconsin and Marquette University   (United States)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

Author keywords

Energy metabolism; Free radicals; Ischaemia; Mitochondria; Reperfusion

Indexed keywords

AMOBARBITAL; CALCIUM; CYTOCHROME C; FLAVINE ADENINE NUCLEOTIDE; OXYGEN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; RINGER SOLUTION; SUPEROXIDE;

AEROBIC METABOLISM; ANIMAL TISSUE; ARTICLE; CELL RESPIRATION; CONTROLLED STUDY; GUINEA PIG; HEART FUNCTION; HEART INFARCTION SIZE; HEART MITOCHONDRION; HEART MUSCLE ISCHEMIA; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; REPERFUSION INJURY; RESPIRATORY CHAIN;

AMOBARBITAL; ANIMALS; CALCIUM; ELECTRON TRANSPORT COMPLEX I; FLAVIN-ADENINE DINUCLEOTIDE; GUINEA PIGS; MYOCARDIAL ISCHEMIA; NADP; OXIDATION-REDUCTION; OXYGEN; REACTIVE OXYGEN SPECIES; SUPEROXIDES; VENTRICULAR FUNCTION, LEFT;

EID: 38849208460     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1016/j.cardiores.2007.08.008     Document Type: Article

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