Roles of reactive oxygen and nitrogen species in pain

Free Radical Biology and Medicine

Volumn 51, Issue 5, 2011, Pages 951-966

  Salvemini, Daniela ^a   Little, Joshua W ^a   Doyle, Timothy ^a   Neumann, William L ^b  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SOUTHERN ILLINOIS UNIVERSITY EDWARDSVILLE   (United States)

Author keywords

Central sensitization; Free radicals; Glutamatergic neurotransmission; Neuroimmune activation; Pain; Peroxynitrite; Peroxynitrite decomposition catalysts; Rostral ventromedial medulla; Superoxide; Superoxide dismutase mimetics

Indexed keywords

ANALGESIC AGENT; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CYCLIC AMP DEPENDENT PROTEIN KINASE; GLUTAMIC ACID; GLUTATHIONE; MANGANESE SUPEROXIDE DISMUTASE; N TERT BUTYL ALPHA PHENYLNITRONE; PEROXYNITRITE; PROSTAGLANDIN SYNTHASE; PROTEIN KINASE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SUPEROXIDE; TEMPOL; TUMOR NECROSIS FACTOR ALPHA; VANILLOID RECEPTOR 1;

ANTIOXIDANT ACTIVITY; APOPTOSIS; CEREBROSPINAL FLUID; DISEASE EXACERBATION; DISEASE SEVERITY; DRUG TARGETING; ENCEPHALITIS; ENZYME CHEMISTRY; HUMAN; HYPERALGESIA; LEARNING; MEMORY; NEUROPATHIC PAIN; NEUROTRANSMISSION; NITRATION; NOCICEPTION; PAIN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

ANALGESICS; ANIMALS; DRUG DESIGN; HUMANS; MOLECULAR TARGETED THERAPY; NEUROGENIC INFLAMMATION; PAIN; PEROXYNITROUS ACID; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SUPEROXIDES;

EID: 80051672206     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.01.026     Document Type: Review

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