메뉴 건너뛰기




Volumn 29, Issue 43, 2009, Pages 13473-13483

A key role for gp130 expressed on peripheral sensory nerves in pathological pain

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN GP 130; INTERLEUKIN 6; PROTEIN KINASE C GAMMA; VANILLOID RECEPTOR 1;

EID: 70350555279     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1822-09.2009     Document Type: Article
Times cited : (122)

References (79)
  • 1
    • 1942423228 scopus 로고    scopus 로고
    • Conditional Gene Deletion in Primary Nociceptive Neurons of Trigeminal Ganglia and Dorsal Root Ganglia
    • DOI 10.1002/gene.20010
    • Agarwal N, Offermanns S, Kuner R (2004) Conditional gene deletion in primary nociceptive neurons of trigeminal ganglia and dorsal root ganglia. Genesis 38:122-129. (Pubitemid 38506849)
    • (2004) Genesis , vol.38 , Issue.3 , pp. 122-129
    • Agarwal, N.1    Offermanns, S.2    Kuner, R.3
  • 3
    • 0034634443 scopus 로고    scopus 로고
    • Further evidence that 3-phosphoinositide-dependent protein kinase-1 (PDK1) is required for the stability and phosphorylation of protein kinase C (PKC) isoforms
    • DOI 10.1016/S0014-5793(00)02162-1, PII S0014579300021621
    • Balendran A, Hare GR, Kieloch A, Williams MR, Alessi DR (2000) Further evidence that 3-phosphoinositide-dependent protein kinase-1 (PDK1) is required for the stability and phosphorylation of protein kinase C (PKC) isoforms. FEBS Lett 484:217-223. (Pubitemid 30811101)
    • (2000) FEBS Letters , vol.484 , Issue.3 , pp. 217-223
    • Balendran, A.1    Hare, G.R.2    Kieloch, A.3    Williams, M.R.4    Alessi, D.R.5
  • 4
  • 5
    • 0037104657 scopus 로고    scopus 로고
    • CAMP-dependent protein kinase regulates desensitization of the capsaicin receptor (VR1) by direct phosphorylation
    • DOI 10.1016/S0896-6273(02)00802-4
    • Bhave G, Zhu W, Wang H, Brasier DJ, Oxford GS, Gereau RW 4th (2002) cAMP-dependent protein kinase regulates desensitization of the capsaicin receptor (VR1) by direct phosphorylation. Neuron 35:721-731. (Pubitemid 35223031)
    • (2002) Neuron , vol.35 , Issue.4 , pp. 721-731
    • Bhave, G.1    Zhu, W.2    Wang, H.3    Brasier, D.J.4    Oxford, G.S.5    Gereau IV, R.W.6
  • 6
    • 0142059776 scopus 로고    scopus 로고
    • Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1)
    • Bhave G, Hu HJ, Glauner KS, Zhu W, Wang H, Brasier DJ, Oxford GS, Gereau RW4th (2003) Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1). Proc Natl Acad Sci U S A 100:12480-12485.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 12480-12485
    • Bhave, G.1    Hu, H.J.2    Glauner, K.S.3    Zhu, W.4    Wang, H.5    Brasier, D.J.6    Oxford, G.S.7    Gereau IV, R.W.8
  • 7
    • 33846218186 scopus 로고    scopus 로고
    • Sensitization of unmyelinated sensory fibers of the joint nerve to mechanical stimuli by interleukin-6 in the rat: An inflammatory mechanism of joint pain
    • DOI 10.1002/art.22282
    • Brenn D, Richter F, Schaible HG (2007) Sensitization of unmyelinated sensory fibers of the joint nerve to mechanical stimuli by interleukin-6 in the rat: an inflammatory mechanism of joint pain. Arthritis Rheum 56:351-359. (Pubitemid 46106209)
    • (2007) Arthritis and Rheumatism , vol.56 , Issue.1 , pp. 351-359
    • Brenn, D.1    Richter, F.2    Schaible, H.-G.3
  • 8
    • 33748979339 scopus 로고    scopus 로고
    • + cells
    • DOI 10.1634/stemcells.2005-0173
    • Campard D, Vasse M, Rose-John S, Poyer F, Lamacz M, Vannier JP (2006) Multilevel regulation of IL-6R by IL-6-sIL-6R fusion protein according to the primitiveness of peripheral blood-derived CD133+ cells. Stem Cells 24:1302-1314. (Pubitemid 44464699)
    • (2006) Stem Cells , vol.24 , Issue.5 , pp. 1302-1314
    • Campard, D.1    Vasse, M.2    Rose-John, S.3    Poyer, F.4    Lamacz, M.5    Vannier, J.-P.6
  • 10
    • 0032825018 scopus 로고    scopus 로고
    • Sense and specificity: A molecular identity for nociceptors
    • Caterina MJ, Julius D (1999) Sense and specificity: a molecular identity for nociceptors. Curr Opin Neurobiol 9:525-530.
    • (1999) Curr Opin Neurobiol , vol.9 , pp. 525-530
    • Caterina, M.J.1    Julius, D.2
  • 11
    • 0030777012 scopus 로고    scopus 로고
    • The capsaicin receptor: A heat-activated ion channel in the pain pathway
    • DOI 10.1038/39807
    • Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, Julius D (1997) The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389:816-824. (Pubitemid 27462969)
    • (1997) Nature , vol.389 , Issue.6653 , pp. 816-824
    • Caterina, M.J.1    Schumacher, M.A.2    Tominaga, M.3    Rosen, T.A.4    Levine, J.D.5    Julius, D.6
  • 13
    • 0033166535 scopus 로고    scopus 로고
    • Specific involvement of PKC-epsilon in sensitization of the neuronal response to painful heat
    • DOI 10.1016/S0896-6273(00)80813-2
    • Cesare P, Dekker LV, Sardini A, Parker PJ, McNaughton P (1999) Specific involvement of PKC-epsilon in sensitization of the neuronal response to painful heat. Neuron 23:617-624. (Pubitemid 29359931)
    • (1999) Neuron , vol.23 , Issue.3 , pp. 617-624
    • Cesare, P.1    Dekker, L.V.2    Sardini, A.3    Parker, P.J.4    McNaughton, P.A.5
  • 14
    • 34548856204 scopus 로고    scopus 로고
    • Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils
    • DOI 10.1182/blood-2007-01-067918
    • Chalaris A, Rabe B, Paliga K, Lange H, Laskay T, Fielding CA, Jones SA, Rose-John S, Scheller J (2007) Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory transsignaling function of neutrophils. Blood 110:1748-1755. (Pubitemid 47443884)
    • (2007) Blood , vol.110 , Issue.6 , pp. 1748-1755
    • Chalaris, A.1    Rabe, B.2    Paliga, K.3    Lange, H.4    Laskay, T.5    Fielding, C.A.6    Jones, S.A.7    Rose-John, S.8    Scheller, J.9
  • 18
    • 0029783630 scopus 로고    scopus 로고
    • Interleukin-6-mediated hyperalgesia/allodynia and increased spinal IL-6 expression in a rat mononeuropathy model
    • DeLeo JA, Colburn RW, Nichols M, Malhotra A (1996) Interleukin-6- mediated hyperalgesia/allodynia and incrased spinal IL-6 expression in a rat mononeuropathy model. J Interferon Cytokine Res 16:695-700. (Pubitemid 26330415)
    • (1996) Journal of Interferon and Cytokine Research , vol.16 , Issue.9 , pp. 695-700
    • Deleo, J.A.1    Colburn, R.W.2    Nichols, M.3    Malhotra, A.4
  • 19
    • 0032145897 scopus 로고    scopus 로고
    • A technique for fast application of heated solutions of different composition to cultured neurones
    • DOI 10.1016/S0165-0270(98)00051-X, PII S016502709800051X
    • Dittert I, Vlachová V, Knotková H, Vitásková Z, Vyklicky L, Kress M, Reeh PW (1998) A technique for fast application of heated solutions of different composition to cultured neurones. J Neurosci Methods 82:195-201. (Pubitemid 28346576)
    • (1998) Journal of Neuroscience Methods , vol.82 , Issue.2 , pp. 195-201
    • Dittert, I.1    Vlachova, V.2    Knotkova, H.3    Vitaskova, Z.4    Vyklicky, L.5    Kress, M.6    Reeh, P.W.7
  • 20
    • 0027133614 scopus 로고
    • Bradykinin initiates cytokine-mediated inflammatory hyperalgesia
    • Ferreira SH, Lorenzetti BB, Poole S (1993) Bradykinin initiates cytokine-mediated inflammatory hyperalgesia. Br J Pharmacol 110:1227-1231.
    • (1993) Br J Pharmacol , vol.110 , pp. 1227-1231
    • Ferreira, S.H.1    Lorenzetti, B.B.2    Poole, S.3
  • 22
    • 0025134244 scopus 로고
    • Automatic classification and analysis of microneurographic spike data using a PC/AT
    • DOI 10.1016/0165-0270(90)90155-9
    • Forster C, Handwerker HO (1990) Automatic classification and analysis of microneurographic spike data using a PC/AT. J Neurosci Methods 31:109-118. (Pubitemid 20044166)
    • (1990) Journal of Neuroscience Methods , vol.31 , Issue.2 , pp. 109-118
    • Forster, C.1    Handwerker, H.O.2
  • 23
    • 0036787278 scopus 로고    scopus 로고
    • Expression of gp130 and leukaemia inhibitory factor receptor subunits in adult rat sensory neurones: Regulation by nerve injury
    • Gardiner NJ, Cafferty WB, Slack SE, Thompson SW (2002) Expression of gp130 and leukaemia inhibitory factor receptor subunits in adult rat sensory neurones: regulation by nerve injury. J Neurochem 83:100-109.
    • (2002) J Neurochem , vol.83 , pp. 100-109
    • Gardiner, N.J.1    Cafferty, W.B.2    Slack, S.E.3    Thompson, S.W.4
  • 25
    • 0023924046 scopus 로고
    • A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia
    • DOI 10.1016/0304-3959(88)90026-7
    • Hargreaves K, Dubner R, Brown F, Flores C, Joris J (1988) A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 32:77-88. (Pubitemid 18149685)
    • (1988) Pain , vol.32 , Issue.1 , pp. 77-88
    • Hargreaves, K.1    Dubner, R.2    Brown, F.3    Flores, C.4    Joris, J.5
  • 27
    • 0033588229 scopus 로고    scopus 로고
    • Protein kinase C delta associates with and phosphorylates Stat3 in an interleukin-6-dependent manner
    • DOI 10.1074/jbc.274.34.24392
    • Jain N, Zhang T, Kee WH, Li W, Cao X (1999) Protein kinase C delta associates with and phosphorylates Stat3 in an interleukin-6-dependent manner. J Biol Chem 274:24392-24400. (Pubitemid 29390380)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.34 , pp. 24392-24400
    • Jain, N.1    Zhang, T.2    Kee, W.H.3    Li, W.4    Cao, X.5
  • 29
    • 0037064542 scopus 로고    scopus 로고
    • The role of soluble receptors in cytokine biology: The agonistic properties of the sIL-6R/IL-6 complex
    • Jones SA, Rose-John S (2002) The role of soluble receptors in cytokine biology: the agonistic properties of the sIL-6R/IL-6 complex. Biochim Biophys Acta 1592:251-263.
    • (2002) Biochim Biophys Acta , vol.1592 , pp. 251-263
    • Jones, S.A.1    Rose-John, S.2
  • 30
    • 0035855860 scopus 로고    scopus 로고
    • Molecular mechanisms of nociception
    • Julius D, Basbaum AI (2001) Molecular mechanisms of nociception. Nature 413:203-210.
    • (2001) Nature , vol.413 , pp. 203-210
    • Julius, D.1    Basbaum, A.I.2
  • 31
    • 1342346561 scopus 로고    scopus 로고
    • 2+/Calmodulin- dependent Kinase II Regulates Its Vanilloid Binding
    • DOI 10.1074/jbc.M311448200
    • Jung J, Shin JS, Lee SY, Hwang SW, Koo J, Cho H, Oh U (2004) Phosphorylation of vanilloid receptor 1 by Ca2+/calmodulin-dependent kinase II regulates its vanilloid binding. J Biol Chem 279:7048-7054. (Pubitemid 38248850)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.8 , pp. 7048-7054
    • Jung, J.1    Shin, J.S.2    Lee, S.-Y.3    Hwang, S.W.4    Koo, J.5    Cho, H.6    Oh, U.7
  • 33
    • 45549090676 scopus 로고    scopus 로고
    • Cytokine mechanisms of central sensitization: Distinct and overlapping role of interleukin-1beta, interleukin-6, and tumor necrosis factor-alpha in regulating synaptic and neuronal activity in the superficial spinal cord
    • Kawasaki Y, Zhang L, Cheng JK, Ji RR (2008) Cytokine mechanisms of central sensitization: distinct and overlapping role of interleukin-1beta, interleukin-6, and tumor necrosis factor-alpha in regulating synaptic and neuronal activity in the superficial spinal cord. J Neurosci 28:5189-5194.
    • (2008) J Neurosci , vol.28 , pp. 5189-5194
    • Kawasaki, Y.1    Zhang, L.2    Cheng, J.K.3    Ji, R.R.4
  • 34
    • 0035123658 scopus 로고    scopus 로고
    • The role of macrophages in immune-mediated damage to the peripheral nervous system
    • DOI 10.1016/S0301-0082(00)00060-5, PII S0301008200000605
    • Kiefer R, Kieseier BC, Stoll G, Hartung HP (2001) The role of macrophages in immune-mediated damage to the peripheral nervous system. Prog Neurobiol 64:109-127. (Pubitemid 32195409)
    • (2001) Progress in Neurobiology , vol.64 , Issue.2 , pp. 109-127
    • Kiefer, R.1    Kieseier, B.C.2    Stoll, G.3    Hartung, H.-P.4
  • 36
    • 0030821372 scopus 로고    scopus 로고
    • Receptive properties of mouse sensory neurons innervating hairy skin
    • Koltzenburg M, Stucky CL, Lewin GR (1997) Receptive properties of mouse sensory neurons innervating hairy skin. J Neurophysiol 78:1841-1850. (Pubitemid 27446968)
    • (1997) Journal of Neurophysiology , vol.78 , Issue.4 , pp. 1841-1850
    • Koltzenburg, M.1    Stucky, C.L.2    Lewin, G.R.3
  • 37
    • 0026779506 scopus 로고
    • Responsiveness and functional attributes of electrically localized terminals of cutaneous C-fibers in vivo and in vitro
    • Kress M, Koltzenburg M, Reeh PW, Handwerker HO (1992) Responsiveness and functional attributes of electrically localized terminals of cutaneous C-fibers in vivo and in vitro. J Neurophysiol 68:581-595.
    • (1992) J Neurophysiol , vol.68 , pp. 581-595
    • Kress, M.1    Koltzenburg, M.2    Reeh, P.W.3    Handwerker, H.O.4
  • 39
    • 33744534577 scopus 로고    scopus 로고
    • Increased sensitivity of desensitized TRPV1 by PMA occurs through PKCepsilon-mediated phosphorylation at S800
    • DOI 10.1016/j.pain.2006.02.016, PII S0304395906000984
    • Mandadi S, Tominaga T, Numazaki M, Murayama N, Saito N, Armati PJ, Roufogalis BD, Tominaga M (2006) Increased sensitivity of desensitized TRPV1 by PMA occurs through PKCepsilon-mediated phosphorylation at S800. Pain 123:106-116. (Pubitemid 43816763)
    • (2006) Pain , vol.123 , Issue.1-2 , pp. 106-116
    • Mandadi, S.1    Tominaga, T.2    Numazaki, M.3    Murayama, N.4    Saito, N.5    Armati, P.J.6    Roufogalis, B.D.7    Tominaga, M.8
  • 40
    • 0032826994 scopus 로고    scopus 로고
    • Neural activities of IL-6-type cytokines often depend on soluble cytokine receptors
    • DOI 10.1046/j.1460-9568.1999.00755.x
    • März P, Otten U, Rose-John S (1999) Neural activities of IL-6-type cytokines often depend on soluble cytokine receptors. Eur J Neurosci 11:2995-3004. (Pubitemid 29431635)
    • (1999) European Journal of Neuroscience , vol.11 , Issue.9 , pp. 2995-3004
    • Marz, P.1    Otten, U.2    Rose-John, S.3
  • 41
    • 0036080482 scopus 로고    scopus 로고
    • TRP channel proteins and signal transduction
    • Minke B, Cook B (2002) TRP channels proteins and signal transduction. Physiol Rev 82:429-472. (Pubitemid 34654458)
    • (2002) Physiological Reviews , vol.82 , Issue.2 , pp. 429-472
    • Minke, B.1    Cook, B.2
  • 42
    • 0346118925 scopus 로고    scopus 로고
    • Desensitization of capsaicin-activated currents in the Vanilloid receptor TRPV1 is decreased by the cyclic AMP-dependent protein kinase pathway
    • Mohapatra DP, Nau C (2003) Desensitization of capsaicin-activated currents in the Vanilloid receptor TRPV1 is decreased by the cyclic AMP-dependent protein kinase pathway. J Biol Chem 278:50080-50090.
    • (2003) J Biol Chem , vol.278 , pp. 50080-50090
    • Mohapatra, D.P.1    Nau, C.2
  • 43
    • 33644875032 scopus 로고    scopus 로고
    • The TRP superfamily of cation channels
    • Montell C (2005) The TRP superfamily of cation channels. Sci STKE 90:re3.
    • (2005) Sci STKE , vol.90
    • Montell, C.1
  • 44
    • 2942614748 scopus 로고    scopus 로고
    • Regulated exocytosis contributes to protein kinase C potentiation of vanilloid receptor activity
    • DOI 10.1074/jbc.M311515200
    • Morenilla-Palao C, Planells-Cases R, García-Sanz N, Ferrer-Montiel A (2004) Regulated exocytosis contributes to protein kinase C potentiation of vanilloid receptor activity. J Biol Chem 279:25665-25672. (Pubitemid 38756829)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.24 , pp. 25665-25672
    • Morenilla-Palao, C.1    Planells-Cases, R.2    Garcia-Sanz, N.3    Ferrer-Montiel, A.4
  • 45
    • 0032968705 scopus 로고    scopus 로고
    • Endogenous interleukin-6 contributes to hypersensitivity to cutaneous stimuli and changes in neuropeptides associated with chronic nerve constriction in mice
    • DOI 10.1046/j.1460-9568.1999.00641.x
    • Murphy PG, Ramer MS, Borthwick L, Gauldie J, Richardson PM, Bisby MA (1999) Endogenous interleukin-6 contributes to hypersensitivity to cutaneous stimuli and changes in neuropeptides asociated with chronic nerve constriction in mice. Eur J Neurosci 11:2243-2253. (Pubitemid 29292318)
    • (1999) European Journal of Neuroscience , vol.11 , Issue.7 , pp. 2243-2253
    • Murphy, P.G.1    Ramer, M.S.2    Borthwick, L.3    Gauldie, J.4    Richardson, P.M.5    Bisby, M.A.6
  • 47
    • 0037147299 scopus 로고    scopus 로고
    • Protein kinase C delta associates with the interleukin-6 receptor subunit glycoprotein (gp) 130 via Stat3 and enhances Stat3-gp130 interaction
    • Novotny-Diermayr V, Zhang T, Gu L, Cao X (2002) Protein kinase C delta associates with the interleukin-6 receptor subunit glycoprotein (gp) 130 via Stat3 and enhances Stat3-gp130 interaction. J Biol Chem 277:49134-49142.
    • (2002) J Biol Chem , vol.277 , pp. 49134-49142
    • Novotny-Diermayr, V.1    Zhang, T.2    Gu, L.3    Cao, X.4
  • 48
    • 0037134417 scopus 로고    scopus 로고
    • Direct phosphorylation of capsaicin receptor VR1 by protein kinase Cepsilon and identification of two target serine residues
    • Numazaki M, Tominaga T, Toyooka H, Tominaga M (2002) Direct phosphorylation of capsaicin receptor VR1 by protein kinase Cepsilon and identification of two target serine residues. J Biol Chem 277:13375-13378.
    • (2002) J Biol Chem , vol.277 , pp. 13375-13378
    • Numazaki, M.1    Tominaga, T.2    Toyooka, H.3    Tominaga, M.4
  • 49
    • 0036212599 scopus 로고    scopus 로고
    • Interleukin-6 in combination with its soluble IL-6 receptor sensitises rat skin nociceptors to heat, in vivo
    • DOI 10.1016/S0304-3959(01)00420-1, PII S0304395901004201
    • Obreja O, Schmelz M, Poole S, Kress M (2002a) Interleukin-6 in combination with its soluble IL-6 receptor sensitises rat skin nociceptors to heat, in vivo. Pain 96:57-62. (Pubitemid 34270628)
    • (2002) Pain , vol.96 , Issue.1-2 , pp. 57-62
    • Obreja, O.1    Schmelz, M.2    Poole, S.3    Kress, M.4
  • 50
    • 0036794671 scopus 로고    scopus 로고
    • IL-1β potentiates heat-activated currents in rat sensory neurons: Involvement of IL-1RI, tyrosine kinase and protein kinase C
    • Obreja O, Rathee PK, Lips KS, Distler C, Kress M (2002b) IL-1β potentiates heat-activated currents in rat sensory neurons: involvement of IL-1RI, tyrosine kinase and protein kinase C. FASEB J 16:1497-1503.
    • (2002) FASEB J , vol.16 , pp. 1497-1503
    • Obreja, O.1    Rathee, P.K.2    Lips, K.S.3    Distler, C.4    Kress, M.5
  • 51
    • 21944443712 scopus 로고    scopus 로고
    • Fast modulation of heat-activated ionic current by proinflammatory interleukin 6 in rat sensory neurons
    • Obreja O, Biasio W, Andratsch M, Lips KS, Rathee PK, Ludwig A, Rose-John S, Kress M (2005) Fast modulation of heat-activated ionic current by proinflammatory interleukin 6 in rat sensory neurons. Brain 128:1634-1641.
    • (2005) Brain , vol.128 , pp. 1634-1641
    • Obreja, O.1    Biasio, W.2    Andratsch, M.3    Lips, K.S.4    Rathee, P.K.5    Ludwig, A.6    Rose-John, S.7    Kress, M.8
  • 52
    • 0029075998 scopus 로고
    • Intracerebroventricular injection of interleukin-6 induces thermal hyperalgesia in rats
    • Oka T, Oka K, Hosoi M, Hori T (1995) Intracerebroventricular injection of interleukin-6 induces thermal hyperalgesia in rats. Brain Res 692:123-128.
    • (1995) Brain Res , vol.692 , pp. 123-128
    • Oka, T.1    Oka, K.2    Hosoi, M.3    Hori, T.4
  • 53
    • 0034663315 scopus 로고    scopus 로고
    • Involvement of the proinflammatory cytokines tumor necrosis factor-α, IL-1β and IL-6 but not IL-8 in the development of heat hyperalgesia: Effects on heat-evoked calcitonin gene-related peptide release from rat skin
    • Oprée A, Kress M (2000) Involvement of the proinflammatory cytokines tumor necrosis factor-α, IL-1β and IL-6 but not IL-8 in the development of heat hyperalgesia: effects on heat-evoked calcitonin gene-related peptide release from rat skin. J Neurosci 20:6289-6293.
    • (2000) J Neurosci , vol.20 , pp. 6289-6293
    • Oprée, A.1    Kress, M.2
  • 54
    • 0032533949 scopus 로고    scopus 로고
    • Interleukin-6 and soluble interleukin-6 receptor: Direct stimulation of gp130 and hematopoiesis
    • Peters M, Müller AM, Rose-John S (1998) Interleukin-6 and soluble interleukin-6 receptor: direct stimulation of gp130 and hematopoiesis. Blood 92:3495-3504.
    • (1998) Blood , vol.92 , pp. 3495-3504
    • Peters, M.1    Müller, A.M.2    Rose-John, S.3
  • 55
    • 3442886198 scopus 로고    scopus 로고
    • Nerve growth factor-induced protein kinase C stimulation contribute to TrkA-dependent inhibition of p75 neurotrophin receptor sphingoliplid signaling
    • DOI 10.1002/jnr.20189
    • Plo I, Bono F, Bezombes C, Alam A, Bruno A, Laurent G (2004) Nerve growth factor-induced protein kinase C stimulation contributes to TrkA-dependent inhibition of p75 neurotrophin receptor sphingolipid signaling. J Neurosci Res 77:465-474. (Pubitemid 39006998)
    • (2004) Journal of Neuroscience Research , vol.77 , Issue.4 , pp. 465-474
    • Plo, I.1    Bono, F.2    Bezombes, C.3    Alam, A.4    Bruno, A.5    Laurent, G.6
  • 57
    • 0034700494 scopus 로고    scopus 로고
    • Induction of vanilloid receptor channel activity by protein kinase C
    • DOI 10.1038/35050121
    • Premkumar LS, Ahern GP (2000) Induction of vanilloid receptor channel activity by protein kinase C. Nature 408:985-990. (Pubitemid 32101646)
    • (2000) Nature , vol.408 , Issue.6815 , pp. 985-990
    • Premkumar, L.S.1    Ahern, G.P.2
  • 58
    • 1342344077 scopus 로고    scopus 로고
    • Enhancement of Potency and Efficacy of NADA by PKC-Mediated Phosphorylation of Vanilloid Receptor
    • DOI 10.1152/jn.00745.2003
    • Premkumar LS, Qi ZH, Van Buren J, Raisinghani M (2004) Enhancement of potency and efficacy of NADA by PKC-mediated phosporylation of vanilloid receptor. J Neurophysiol 91:1442-1449. (Pubitemid 38250421)
    • (2004) Journal of Neurophysiology , vol.91 , Issue.3 , pp. 1442-1449
    • Premkumar, L.S.1    Qi, Z.-H.2    Van Buren, J.3    Raisinghani, M.4
  • 60
    • 0022903329 scopus 로고
    • Sensory receptors in mammalian skin in an in vitro preparation
    • DOI 10.1016/0304-3940(86)90180-1
    • Reeh PW (1986) Sensory receptors in mammalian skin in an in vitro preparation. Neurosci Lett 66:141-146. (Pubitemid 16068921)
    • (1986) Neuroscience Letters , vol.66 , Issue.2 , pp. 141-146
    • Reeh, P.W.1
  • 61
    • 0028226196 scopus 로고
    • Soluble receptors for cytokines and growth factors: Generation and biological function
    • Rose-John S, Heinrich PC (1994) Soluble receptors for cytokines and growth factors: generation and biological function. Biochem J 300: 281-290. (Pubitemid 24167878)
    • (1994) Biochemical Journal , vol.300 , Issue.2 , pp. 281-290
    • Rose-John, S.1    Heinrich, P.C.2
  • 62
    • 33748848714 scopus 로고    scopus 로고
    • Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: Role in inflammation and cancer
    • DOI 10.1189/jlb.1105674
    • Rose-John S, Scheller J, Elson G, Jones SA (2006) Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer. J Leukoc Biol 80:227-236. (Pubitemid 44835496)
    • (2006) Journal of Leukocyte Biology , vol.80 , Issue.2 , pp. 227-236
    • Rose-John, S.1    Scheller, J.2    Elson, G.3    Jones, S.A.4
  • 64
    • 2442754920 scopus 로고    scopus 로고
    • The IL-6/sIL-6R fusion protein hyper-IL-6 promotes neurite outgrowth and neuron survival in cultured enteric neurons
    • Schäfer KH, Mestres P, März P, Rose-John S (1999) The IL-6/sIL-6R fusion protein hyper-IL-6 promotes neurite outgrowth and neuron survival in cultured enteric neurons. J Interferon Cytokine Res 19:527-532.
    • (1999) J Interferon Cytokine Res , vol.19 , pp. 527-532
    • Schäfer, K.H.1    Mestres, P.2    März, P.3    Rose-John, S.4
  • 66
    • 0032102096 scopus 로고    scopus 로고
    • TRP, TRPL and trouble in photoreceptor cells
    • Scott K, Zuker C (1998) TRP, TRPL and trouble in photoreceptor cells. Curr Opin Neurobiol 8:383-388.
    • (1998) Curr Opin Neurobiol , vol.8 , pp. 383-388
    • Scott, K.1    Zuker, C.2
  • 68
    • 40749114497 scopus 로고    scopus 로고
    • Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): A double-blind, placebo-controlled, randomised trial
    • OPTION investigators
    • Smolen JS, Beaulieu A, Rubbert-Roth A, Ramos-Remus C, Rovensky J, Alecock E, Woodworth T, Alten R, OPTION investigators (2008) Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial. Lancet 371:987-997.
    • (2008) Lancet , vol.371 , pp. 987-997
    • Smolen, J.S.1    Beaulieu, A.2    Rubbert-Roth, A.3    Ramos-Remus, C.4    Rovensky, J.5    Alecock, E.6    Woodworth, T.7    Alten, R.8
  • 69
    • 34548511124 scopus 로고    scopus 로고
    • Rottlerin: An inappropirate and ineffective inhibitor of PKCδ
    • Soltoff SP (2007) Rottlerin: an inappropirate and ineffective inhibitor of PKCδ. Trends Pharmacol Sci 28:453-458.
    • (2007) Trends Pharmacol Sci , vol.28 , pp. 453-458
    • Soltoff, S.P.1
  • 70
    • 33750524257 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane
    • DOI 10.1085/jgp.200609576
    • Stein AT, Ufret-Vincenty CA, Hua L, Santana LF, Gordon SE (2006) Phosphoinosite 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane. J Gen Physiol 128:509-522. (Pubitemid 44664629)
    • (2006) Journal of General Physiology , vol.128 , Issue.5 , pp. 509-522
    • Stein, A.T.1    Ufret-Vincenty, C.A.2    Hua, L.3    Santana, L.F.4    Gordon, S.E.5
  • 71
    • 0036310523 scopus 로고    scopus 로고
    • Bradykinin lowers the threshold temperature for heat activation of vanilloid receptor 1
    • Sugiura T, Tominaga M, Katsuya H, Mizumura K (2002) Bradykinin lowers the threshold temperature for heat activation of vanilloid receptor 1. J Neurophysiol 88:544-548. (Pubitemid 34755376)
    • (2002) Journal of Neurophysiology , vol.88 , Issue.1 , pp. 544-548
    • Sugiura, T.1    Tominaga, M.2    Mizumura, H.K.K.3
  • 72
  • 73
    • 0035425705 scopus 로고    scopus 로고
    • Protein kinase C activation potentiates gating of the vanilloid receptor VR1 by capsaicin, protons, heat and anandamide
    • DOI 10.1111/j.1469-7793.2001.00813.x
    • Vellani V, Mapplebeck S, Moriondo A, Davis JB, McNaughton PA (2001) Protein kinase C activation potentiates gating of the vanilloid receptor VR-1 by capsaicin, protons, heat and anandamide. J Physiol 534:813-825. (Pubitemid 32700878)
    • (2001) Journal of Physiology , vol.534 , Issue.3 , pp. 813-825
    • Vellani, V.1    Mapplebeck, S.2    Moriondo, A.3    Davis, J.B.4    McNaughton, P.A.5
  • 74
    • 0031441582 scopus 로고    scopus 로고
    • Nociceptive responses in interleukin-6-deficient mice to peripheral inflammation and peripheral nerve section
    • DOI 10.1006/cyto.1997.0243
    • Xu XJ, Hao JX, Andell-Jonsson S, Poli V, Bartfai T, Wiesenfeld-Hallin Z (1997) Nociceptive responses in interleukin-6-deficient mice to peripheral inflammation and peripheral nerve section. Cytokine 9:1028-1033. (Pubitemid 28026670)
    • (1997) Cytokine , vol.9 , Issue.12 , pp. 1028-1033
    • Xu, X.-J.1    Hao, J.-X.2    Andell-Jonsson, S.3    Poli, V.4    Bartfai, T.5    Wiesenfeld-Hallin, Z.6
  • 76
    • 34249006580 scopus 로고    scopus 로고
    • Protein kinase C delta negatively regulates tyrosine hydroxylase activity and dopamine synthesis by enhancing protein phosphatase-2A activity in dopaminergic neurons
    • DOI 10.1523/JNEUROSCI.4107-06.2007
    • Zhang D, Kanthasamy A, Yang Y, Anantharam V, Kanthasamy A (2007) Protein kinase C delta negatively regulates tyrosine hydroxylase activity and dopamine synthesis by enhancing protein phosphatase-2A activity in dopaminergic neurons. J Neurosci 27:5349-5362. (Pubitemid 46790158)
    • (2007) Journal of Neuroscience , vol.27 , Issue.20 , pp. 5349-5362
    • Zhang, D.1    Kanthasamy, A.2    Yang, Y.3    Anantharam, V.4    Kanthasamy, A.5
  • 77
    • 29244484493 scopus 로고    scopus 로고
    • NGF rapidly increases membrane expression of TRPV1 heat-gated ion channels
    • DOI 10.1038/sj.emboj.7600893
    • Zhang X, Huang J, McNaughton PA (2005) NGF rapidly increases membrane expression of TRPV1 heat-gated ion channels. EMBO J 24:4211-4223. (Pubitemid 41828897)
    • (2005) EMBO Journal , vol.24 , Issue.24 , pp. 4211-4223
    • Zhang, X.1    Huang, J.2    McNaughton, P.A.3
  • 78
    • 33947672465 scopus 로고    scopus 로고
    • Phosphoinositide-3-kinase and mitogen activated protein kinase signaling pathways mediate acute NGF sensitization of TRPV1
    • DOI 10.1016/j.mcn.2007.01.005, PII S1044743107000140
    • Zhu W, Oxford GS (2007) Phosphoinositide-3-kinase and mitogen activated protein kinase signaling pathways mediate acute NGF sensitization of TRPV1. Mol Cell Neurosci 34:689-700. (Pubitemid 46486710)
    • (2007) Molecular and Cellular Neuroscience , vol.34 , Issue.4 , pp. 689-700
    • Zhu, W.1    Oxford, G.S.2
  • 79
    • 4644250844 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization
    • DOI 10.1523/JNEUROSCI.2893-04.2004
    • Zhuang ZY, Xu H, Clapham DE, Ji RR (2004) Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization. J Neurosci 24:8300-8309. (Pubitemid 39280809)
    • (2004) Journal of Neuroscience , vol.24 , Issue.38 , pp. 8300-8309
    • Zhuang, Z.-Y.1    Xu, H.2    Clapham, D.E.3    Ji, R.-R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.