Expression of spinal NMDA receptor and PKCγ after chronic morphine is regulated by spinal glucocorticoid receptor

Journal of Neuroscience

Volumn 25, Issue 48, 2005, Pages 11145-11154

  Lim, Grewo ^a   Wang, Shuxing ^a   Zeng, Qing ^a   Sung, Backil ^a   Yang, Liling ^a   Mao, Jianren ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Adenylyl cyclase; cAMP response element binding protein; CREB; Glucocorticoid receptor; Morphine tolerance; NMDA receptor; Protein kinase A; Protein kinase C; RU38486

Indexed keywords

2',5' DIDEOXYADENOSINE; ADENYLATE CYCLASE ACTIVATOR; ADENYLATE CYCLASE INHIBITOR; COMPLEMENTARY DNA; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FORSKOLIN; GLUCOCORTICOID RECEPTOR; GLUCOCORTICOID RECEPTOR ANTAGONIST; MIFEPRISTONE; MORPHINE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; OLIGODEOXYNUCLEOTIDE; PROTEIN KINASE C GAMMA; RECEPTOR SUBUNIT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DRUG TOLERANCE; ENZYME REGULATION; MALE; MOLECULAR INTERACTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; SPINAL CORD; SPINAL CORD DORSAL HORN; UPREGULATION;

ADENYLATE CYCLASE; ANIMALS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DEXAMETHASONE; DRUG ADMINISTRATION SCHEDULE; GLUCOCORTICOIDS; HORMONE ANTAGONISTS; MALE; MIFEPRISTONE; MORPHINE; OLIGONUCLEOTIDES, ANTISENSE; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GLUCOCORTICOID; RECEPTORS, N-METHYL-D-ASPARTATE; SPINAL CORD;

EID: 30644480427     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3768-05.2005     Document Type: Article

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