Oxidative stress on EAAC1 is involved in MPTP-induced glutathione depletion and motor dysfunction

European Journal of Neuroscience

Volumn 27, Issue 1, 2008, Pages 20-30

  Aoyama, Koji ^a   Matsumura, Nobuko ^a   Watabe, Masahiko ^a   Nakaki, Toshio ^a  

^a TEIKYO UNIVERSITY   (Japan)

Author keywords

Amino acid transporters; N acetylcysteine; Oxidative stress; Parkinson's disease

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; 3 NITROTYROSINE; 7 NITROINDAZOLE; ACETYLCYSTEINE; ASPARTIC ACID BETA HYDROXAMIC ACID; CYSTEINE; EXCITATORY AMINO ACID TRANSPORTER 3; GLUTAMATE TRANSPORTER; GLUTATHIONE; HYDROGEN PEROXIDE; NITRIC OXIDE SYNTHASE INHIBITOR;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; DEGENERATIVE DISEASE; DOPAMINERGIC NERVE CELL; MALE; MOTOR ACTIVITY; MOTOR DYSFUNCTION; MOUSE; NERVE CELL; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; SUBSTANTIA NIGRA;

1-METHYL-4-PHENYLPYRIDINIUM; ACETYLCYSTEINE; ANIMALS; ASPARTIC ACID; BEHAVIOR, ANIMAL; CYSTEINE; DISEASE MODELS, ANIMAL; DRUG INTERACTIONS; EXCITATORY AMINO ACID TRANSPORTER 1; FREE RADICAL SCAVENGERS; GLUTATHIONE; HUMANS; HYDROGEN PEROXIDE; HYDROXAMIC ACIDS; INDAZOLES; MALE; MICE; MICE, INBRED C57BL; MOVEMENT DISORDERS; MPTP POISONING; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; SUBSTANTIA NIGRA;

EID: 37748999265     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2007.05979.x     Document Type: Article

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