The glycine site-specific NMDA antagonist (+)-HA966 enhances the effect of morphine and reverses morphine tolerance via a spinal mechanism

Neuropharmacology

Volumn 54, Issue 3, 2008, Pages 588-596

  Adam, Frédéric ^a,b,c   Dufour, Eric ^a,d   Le Bars, Daniel ^a,b  

^a INSERM   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c HÔPITAL AMBROISE PARÉ   (France)

^d FOCH HOSPITAL   (France)

Author keywords

Analgesia; C fibre reflex; Morphine tolerance; NMDA receptor; Spinal

Indexed keywords

3 AMINO 1 HYDROXY 2 PYRROLIDINONE; GLYCINE; MORPHINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN STEM; BRAIN SURGERY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; DRUG TOLERANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHAM PROCEDURE; SPINAL CORD;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, RADIATION; DRUG TOLERANCE; ELECTRIC STIMULATION; ELECTROMYOGRAPHY; EXCITATORY AMINO ACID ANTAGONISTS; MALE; MORPHINE; MORPHINE DEPENDENCE; NERVE FIBERS, UNMYELINATED; PAIN MEASUREMENT; PYRROLIDINONES; RATS; RATS, SPRAGUE-DAWLEY; REFLEX; SPINAL CORD; SPINAL CORD INJURIES;

EID: 38649102166     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2007.11.013     Document Type: Article

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