TEMPOL, a membrane-permeable radical scavenger, attenuates peroxynitrite- and superoxide anion-enhanced carrageenan-induced paw edema and hyperalgesia: A key role for superoxide anion

European Journal of Pharmacology

Volumn 548, Issue 1-3, 2006, Pages 167-173

  Khattab, Mahmoud M ^a  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Carrageenan; Hyperalgesia; Paw edema; Peroxynitrite; SOD mimetic; Superoxide anion; TEMPOL

Indexed keywords

CARRAGEENAN; DIETHYLTHIOCARBAMATE; PEROXYNITRITE; SUPEROXIDE; TEMPOL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; HYPERALGESIA; INFLAMMATION; MALE; MOUSE; NONHUMAN; PAIN; PAW EDEMA; PRIORITY JOURNAL;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CARRAGEENAN; CYCLIC N-OXIDES; EDEMA; ENZYME INHIBITORS; FOOT; FREE RADICAL SCAVENGERS; HEAT; HOT TEMPERATURE; HYPERALGESIA; MALE; NITRIC OXIDE DONORS; PENICILLAMINE; PEROXYNITROUS ACID; PYROGALLOL; RATS; RATS, WISTAR; SPIN LABELS; SUPEROXIDE DISMUTASE; SUPEROXIDES; THIOCARBAMATES;

EID: 33748704531     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2006.08.007     Document Type: Article

References (32)

1. Beckman J.S., Beckman T.W., Chen J., Marshall P.A., and Freman B.A. Apparent hydroxyl radical production by peroxynitrite: implication for endothelial injury from nitric oxide and superoxide. Proc. Natl. Acad. Sci. U. S. A. 87 (1990) 1620-1624
2. Crow J.P., and Beckman J.S. The role of peroxynitrite in nitric oxide-mediated toxicity. Curr. Top. Microbiol. Immunol. 196 (1995) 57-73
3. Cuzzocrea S., Zingarelli B., Gilard E., Hake P., Salzman A.L., and Szabó C. Protective effect of melatonin in carrageenan-induced models of local inflammation. J. Pineal Res. 23 (1997) 106-116
4. Cuzzocrea S., Zingarelli B., Gilard E., Hake P., Salzman A.L., and Szabó C. Anti-inflammatory effects of mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxynitrite scavenger, in carrageenan-induced models of inflammation. Free Radic. Biol. Med. 24 (1998) 450-459
5. Cuzzocrea S., Costantino G., Mazzon E., and Caputi A.P. Beneficial effects of raxofelast (IRFI 016), a new hydrophilic vitamin e-like antioxidant, in carrageenan-induced pleurisy. Br. J. Pharmacol. 126 (1999) 407-414
6. Cuzzocrea S., Zingarelli B., Costantino G., and Caputi A.P. Beneficial effects of Mn(III)tetrakis (4-benzoic acid) porphyrin (MnTBAP), a superoxide dismutase mimetic, in carrageenan-pleurisy. Free Radic. Biol. Med. 26 (1999) 26-33
7. Cuzzocrea S., Tan D.X., Costantino G., Mazzon E., Caputi A.P., and Reiter R.J. The protective role of endogenous melatonin in carrageenan-induced pleurisy in the rat. FASEB J. 13 (1999) 1930-1938
8. Cuzzocrea S., Costantino G., Zingarelli B., Mazzon E., Micali A., and Caputi A.P. The protective role of endogenous glutathione in carrageenan-induced pleurisy in the rat. Eur. J. Pharmacol. 372 (1999) 187-197
9. Cuzzocrea S., McDonald M.C., Filipe H.M., Costantino G., Mazzon E., Santagati S., Caputi A.P., and Thiemermann C. Effects of tempol, a membrane-permeable radical scavenger, in a rodent model of carrageenan-induced pleurisy. Eur. J. Pharmacol. 390 (2000) 209-222
10. Cuzzocrea S., Mazzon E., Dugo L., Serraino I., Ciccolo A., Centorrino T., De Sarro A., and Caputi A.P. Protective effects of n-acetylcysteine on lung injury and red blood cell modification induced by carrageenan in the rat. FASEB J. 15 (2001) 1187-1200
11. Cuzzocrea S., Pisano B., Dugo L., Ianaro A., Patel N.S., Caputi A.P., and Thiemermann C. Tempol reduces the activation of nuclear factor-kappaB in acute inflammation. Free Radic. Res. 38 (2004) 813-819
12. Di Paola R., Mazzon E., Zito D., Maiere D., Britti D., Genovese T., and Cuzzocrea S. Effects of Tempol, a membrane-permeable radical scavenger, in a rodent model periodontitis. J. Clin. Periodontol. 32 10 (2005) 1062-1068
13. Dugo L., Serraino I., Fulia F., De Sarro A., Caputi A.P., and Cuzzocrea S. Effect of melatonin on cellular energy depletion mediated by peroxynitrite and poly (ADP-ribose) synthetase activation in an acute model of inflammation. J. Pineal Res. 31 (2001) 76-84
14. Gulcin I., Beydemir S., Alici H.A., Elmastas M., and Buyukokuroglu M.E. In vitro antioxidant properties of morphine. Pharmacol. Res. 49 (2004) 59-66
15. Ikeda Y., Matsumoto K., Dohi K., Jimbo H., Sasaki K., and Satoh K. Direct superoxide scavenging activity of nonsteroidal anti-inflammatory drugs: determination by electron spin resonance using the spin trap method. Headache 41 (2001) 138-141
16. Inoue S., and Kawanishi S. Oxidative DNA damage induced by simultaneous generation of nitric oxide and superoxide. FEBS Lett. 371 (1995) 86-88
17. Jerez S., Peral de Bruno M., and Coviello A. Nitric oxide modulates angiotensin II-induced endothelial vasoconstrictor prostanoid release. Eur. J. Pharmacol. 27 520 (2005) 127-134
18. Lavich T.R., Cordeiro R.S.B., Silva P.M.R., and Martins M.A. A novel hot-plate test sensitive to hyperalgesic stimuli and non-opioid analgesics. Braz. J. Med. Biol. Res. 38 (2005) 445-451
19. Marzocco S., Di Paola R., Serraino I., Sorrentino R., Meli R., Mattaceraso G., Cuzzocrea S., Pinto A., and Autore G. Effect of methylguanidine in carrageenan-induced acute inflammation in the rats. Eur. J. Pharmacol. 484 (2004) 341-350
20. Misra H.P. Reaction of copper-zinc superoxide dismutase with diethylthiocarbamate. J. Biol. Chem. 254 (1979) 11623-11628
21. Mitchell J.B., Samuni A., Krishna M.C., DeGraff W.G., Ahn M.S., Samuni U., and Russo A. Biologically active metal independent superoxide dismutase mimics. Biochemistry 29 (1990) 2802-2807
22. Oyanagui Y. Inflammation and superoxide production by macrophages. Agents Actions Suppl. 7 (1980) 174-179
23. Oyanagui Y., Sato S., and Okajima T. Suppressions of ischemic paw oedema in mice, rats and guinea pigs by superoxide dismutases from different sources. Free Radic. Res. Commun. 4 (1988) 385-396
24. Phelps D.T., Ferro T.J., Higgins P.J., Shankar R., Parker D.M., and Johnson M. TNF-alpha induces peroxynitrite-mediated depletion of lung endothelial glutathione via protein kinase C. Am. J. Physiol. 269 (1995) L551-L559
25. Rodenas J., Mitjavila M.T., and Carbonell T. Simultaneous generation of nitric oxide and superoxide by inflammatory cells in rats. Free Radic. Biol. Med. 18 5 (1995) 869-875
26. Salvemini D., Wang Z.Q., Bourdon D.M., Stern M.K., Currie M.G., and Manning P.T. Evidence of peroxynitrite involvement in the carrageenan-induced rat paw edema. Eur. J. Pharmacol. 303 (1996) 217-220
27. Salvemini D., Wang Z.Q., Wyatt P., Bourdon D.M., Marino M.H., Manning P.T., and Currie M.G. Nitric oxide: a key mediator in the early and late phase of carrageenan-induced rat paw inflammation. Br. J. Pharmacol. 118 (1996) 829-838
28. Salvemini D., Wang Z.Q., Stern M.K., Currie M.G., and Misko T.P. Peroxynitrite decomposition catalysts: therapeutics for peroxynitrite-mediated pathology. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 2659-2663
29. Salvemini D., Mazzon E., Dugo L., Riley D.P., Serraino I., Caputi A.P., and Cuzzocrea S. Pharmacological manipulation of the inflammatory cascade by the superoxide dismutase mimetic, M40403. Br. J. Pharmacol. 132 (2001) 815-827
30. Vinegar R., Schreiber W., and Hugo R. Biphasic development of carrageenan edema in rats. J. Pharmacol. Exp. Ther. 166 (1969) 96-103
31. Wang Z.Q., Porreca F., Cuzzocrea S., Galen K., Lightfoot R., Masini E., Muscoli C., Mollace V., Ndengele M., Ischiropoulos H., and Salvemini D. A newly identified role for superoxide in inflammatory pain. J. Pharmacol. Exp. Ther. 309 (2004) 869-878
32. Xie Y.-U., Kaminski P.M., and Wolin M.S. Inhibition of rat cardiac muscle contraction mitochondrial respiration by endogenous peroxynitrite formation during posthypoxic reoxygenation. Circ. Res. 82 (1998) 891-897