Prostaglandin E2-induced sensitization of bradykinin-evoked responses in rat dorsal root ganglion neurons is mediated by cAMP-dependent protein kinase A

European Journal of Neuroscience

Volumn 12, Issue 9, 2000, Pages 3250-3258

  Smith, Jacqueline A M ^a,b   Davis, Clare L ^a   Burgess, Gillian M ^a,c  

^a Novatis Inst for Medical Sciences   (United Kingdom)

^b Advanced Medicine Inc   (United States)

^c PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

Intracellular calcium; Kinin; Prostanoid; Sensory neuron; Substance P

Indexed keywords

BRADYKININ; CYCLIC AMP DEPENDENT PROTEIN KINASE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE PHOSPHODIESTERASE; PROSTACYCLIN; PROSTAGLANDIN E2; PROSTAGLANDIN F2; SUBSTANCE P; ADENYLATE CYCLASE; BUCLADESINE; CALCIUM; DIAGNOSTIC AGENT; ENZYME INHIBITOR; FORSKOLIN; INOSITOL 1,4,5 TRISPHOSPHATE; ISOQUINOLINE DERIVATIVE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; SULFONAMIDE; TRITIUM;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL SUBPOPULATION; EXTRACELLULAR CALCIUM; NERVE CELL CULTURE; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; RAT; SECOND MESSENGER; SENSITIZATION; SENSORY NERVE CELL; SPINAL GANGLION; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; ENZYMOLOGY; METABOLISM; SPRAGUE DAWLEY RAT;

ADENYLATE CYCLASE; ANIMALS; BRADYKININ; BUCLADESINE; CALCIUM; CELLS, CULTURED; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DINOPROSTONE; DRUG SYNERGISM; ENZYME INHIBITORS; FORSKOLIN; GANGLIA, SPINAL; INOSITOL 1,4,5-TRISPHOSPHATE; ISOQUINOLINES; NEURONS, AFFERENT; RATS; RATS, SPRAGUE-DAWLEY; SUBSTANCE P; SULFONAMIDES; TRITIUM;

EID: 0033623176     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2000.00218.x     Document Type: Article

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