-
1
-
-
1642499152
-
β-Amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase
-
Abramov AY, Canevari L, Duchen MR (2004) β-Amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase. J Neurosci 24:565-575.
-
(2004)
J Neurosci
, vol.24
, pp. 565-575
-
-
Abramov, A.Y.1
Canevari, L.2
Duchen, M.R.3
-
2
-
-
33747227271
-
Protease-activated receptor 2 sensitizes TRPV1 by protein kinase Cepsilon- and A-dependent mechanisms in rats and mice
-
Amadesi S, Cottrell GS, Divino L, Chapman K, Grady EF, Bautista F, Karanjia R, Barajas-Lopez C, Vanner S, Vergnolle N, Bunnett NW (2006) Protease-activated receptor 2 sensitizes TRPV1 by protein kinase Cepsilon- and A-dependent mechanisms in rats and mice. J Physiol 575:555-571.
-
(2006)
J Physiol
, vol.575
, pp. 555-571
-
-
Amadesi, S.1
Cottrell, G.S.2
Divino, L.3
Chapman, K.4
Grady, E.F.5
Bautista, F.6
Karanjia, R.7
Barajas-Lopez, C.8
Vanner, S.9
Vergnolle, N.10
Bunnett, N.W.11
-
3
-
-
0037104657
-
-
Bhave G, Zhu W, Wang H, Brasier DJ, Oxford GS, Gereau RW 4th (2002) cAMP-dependent protein kinase regulates desensitization of the capsaicin receptor (VR1) by direct phosphorylation. Neuron 35:721-731.
-
Bhave G, Zhu W, Wang H, Brasier DJ, Oxford GS, Gereau RW 4th (2002) cAMP-dependent protein kinase regulates desensitization of the capsaicin receptor (VR1) by direct phosphorylation. Neuron 35:721-731.
-
-
-
-
4
-
-
0034646740
-
Impaired nociception and pain sensation in mice lacking the capsaicin receptor
-
Caterina MJ, Leffler A, Malmberg AB, Martin WJ, Trafton J, Petersen-Zeitz KR, Koltzenburg M, Basbaum AI, Julius D (2000) Impaired nociception and pain sensation in mice lacking the capsaicin receptor. Science 288:306-313.
-
(2000)
Science
, vol.288
, pp. 306-313
-
-
Caterina, M.J.1
Leffler, A.2
Malmberg, A.B.3
Martin, W.J.4
Trafton, J.5
Petersen-Zeitz, K.R.6
Koltzenburg, M.7
Basbaum, A.I.8
Julius, D.9
-
5
-
-
0030446311
-
A novel heat-activated current in nociceptive neurons and its sensitization by bradykinin
-
Cesare P, McNaughton P (1996) A novel heat-activated current in nociceptive neurons and its sensitization by bradykinin. Proc Natl Acad Sci U S A 93:15435-15439.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 15435-15439
-
-
Cesare, P.1
McNaughton, P.2
-
6
-
-
0033166535
-
Specific involvement of PKC-epsilon in sensitization of the neuronal response to painful heat
-
Cesare P, Dekker LV, Sardini A, Parker PJ, McNaughton PA (1999) Specific involvement of PKC-epsilon in sensitization of the neuronal response to painful heat. Neuron 23:617-624.
-
(1999)
Neuron
, vol.23
, pp. 617-624
-
-
Cesare, P.1
Dekker, L.V.2
Sardini, A.3
Parker, P.J.4
McNaughton, P.A.5
-
7
-
-
0035927651
-
Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition
-
Chuang HH, Prescott ED, Kong H, Shields S, Jordt SE, Basbaum AI, Chao MV, Julius D (2001) Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition. Nature 411:957-962.
-
(2001)
Nature
, vol.411
, pp. 957-962
-
-
Chuang, H.H.1
Prescott, E.D.2
Kong, H.3
Shields, S.4
Jordt, S.E.5
Basbaum, A.I.6
Chao, M.V.7
Julius, D.8
-
8
-
-
0023924046
-
A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia
-
Hargreaves K, Dubner R, Brown F, Flores C, Joris J (1988) A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 32:77-88.
-
(1988)
Pain
, vol.32
, pp. 77-88
-
-
Hargreaves, K.1
Dubner, R.2
Brown, F.3
Flores, C.4
Joris, J.5
-
9
-
-
0036758636
-
-
Hu HJ, Bhave G, Gereau RW 4th (2002) Prostaglandin and protein kinase A-dependent modulation of vanilloid receptor function by metabotropic glutamate receptor 5: potential mechanism for thermal hyperalgesia. J Neurosci 22:7444-7452.
-
Hu HJ, Bhave G, Gereau RW 4th (2002) Prostaglandin and protein kinase A-dependent modulation of vanilloid receptor function by metabotropic glutamate receptor 5: potential mechanism for thermal hyperalgesia. J Neurosci 22:7444-7452.
-
-
-
-
10
-
-
33646140915
-
NOX1/NADPH oxidase negatively regulates nerve growth factor-induced neurite outgrowth
-
Ibi M, Katsuyama M, Fan C, Iwata K, Nishinaka T, Yokoyama T, Yabe-Nishimura C (2006) NOX1/NADPH oxidase negatively regulates nerve growth factor-induced neurite outgrowth. Free Radic Biol Med 40:1785-1795.
-
(2006)
Free Radic Biol Med
, vol.40
, pp. 1785-1795
-
-
Ibi, M.1
Katsuyama, M.2
Fan, C.3
Iwata, K.4
Nishinaka, T.5
Yokoyama, T.6
Yabe-Nishimura, C.7
-
11
-
-
0037124093
-
Importance of C1B domain for lipid messenger-induced targeting of protein kinase C
-
Kashiwagi K, Shirai Y, Kuriyama M, Sakai N, Saito N (2002) Importance of C1B domain for lipid messenger-induced targeting of protein kinase C. J Biol Chem 277:18037-18045.
-
(2002)
J Biol Chem
, vol.277
, pp. 18037-18045
-
-
Kashiwagi, K.1
Shirai, Y.2
Kuriyama, M.3
Sakai, N.4
Saito, N.5
-
12
-
-
0000396616
-
A novel nociceptor signaling pathway revealed in protein kinase C epsilon mutant mice
-
Khasar SG, Lin YH, Martin A, Dadgar J, McMahon T, Wang D, Hundle B, Aley KO, Isenberg W, McCarter G, Green PG, Hodge CW, Levine JD, Messing RO (1999) A novel nociceptor signaling pathway revealed in protein kinase C epsilon mutant mice. Neuron 24:253-260.
-
(1999)
Neuron
, vol.24
, pp. 253-260
-
-
Khasar, S.G.1
Lin, Y.H.2
Martin, A.3
Dadgar, J.4
McMahon, T.5
Wang, D.6
Hundle, B.7
Aley, K.O.8
Isenberg, W.9
McCarter, G.10
Green, P.G.11
Hodge, C.W.12
Levine, J.D.13
Messing, R.O.14
-
13
-
-
33748704531
-
TEMPOL, a membrane-permeable radical scavenger, attenuates peroxynitrite- and superoxide anion-enhanced carrageenan-induced paw edema and hyperalgesia: A key role for superoxide anion
-
Khattab MM (2006) TEMPOL, a membrane-permeable radical scavenger, attenuates peroxynitrite- and superoxide anion-enhanced carrageenan-induced paw edema and hyperalgesia: a key role for superoxide anion. Eur J Pharmacol 548:167-173.
-
(2006)
Eur J Pharmacol
, vol.548
, pp. 167-173
-
-
Khattab, M.M.1
-
14
-
-
0035798603
-
N-acetylcysteine induces cell cycle arrest in hepatic stellate cells through its reducing activity
-
Kim KY, Rhim T, Choi I, Kim SS (2001) N-acetylcysteine induces cell cycle arrest in hepatic stellate cells through its reducing activity. J Biol Chem 276:40591-40598.
-
(2001)
J Biol Chem
, vol.276
, pp. 40591-40598
-
-
Kim, K.Y.1
Rhim, T.2
Choi, I.3
Kim, S.S.4
-
15
-
-
0034604723
-
Superoxide-induced stimulation of protein kinase C via thiol modification and modulation of zinc content
-
Knapp LT, Klann E (2000) Superoxide-induced stimulation of protein kinase C via thiol modification and modulation of zinc content. J Biol Chem 275:24136-24145.
-
(2000)
J Biol Chem
, vol.275
, pp. 24136-24145
-
-
Knapp, L.T.1
Klann, E.2
-
17
-
-
0017393239
-
Effects of central depressants on rota-rod and traction performances in mice
-
Kuribara H, Higuchi Y, Tadokoro S (1977) Effects of central depressants on rota-rod and traction performances in mice. Jpn J Pharmacol 27:117-126.
-
(1977)
Jpn J Pharmacol
, vol.27
, pp. 117-126
-
-
Kuribara, H.1
Higuchi, Y.2
Tadokoro, S.3
-
18
-
-
1542406446
-
NOX enzymes and the biology of reactive oxygen
-
Lambeth JD (2004) NOX enzymes and the biology of reactive oxygen. Nat Rev Immunol 4:181-189.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 181-189
-
-
Lambeth, J.D.1
-
19
-
-
17144369501
-
Oxidative activation of protein kinase Cgamma through the C1 domain. Effects on gap junctions
-
Lin D, Takemoto DJ (2005) Oxidative activation of protein kinase Cgamma through the C1 domain. Effects on gap junctions. J Biol Chem 280:13682-13693.
-
(2005)
J Biol Chem
, vol.280
, pp. 13682-13693
-
-
Lin, D.1
Takemoto, D.J.2
-
20
-
-
27444441677
-
Nox1 is involved in angiotensin II-mediated hypertension: A study in Nox1-deficient mice
-
Matsuno K, Yamada H, Iwata K, Jin D, Katsuyama M, Matsuki M, Takai S, Yamanishi K, Miyazaki M, Matsubara H, Yabe-Nishimura C (2005) Nox1 is involved in angiotensin II-mediated hypertension: a study in Nox1-deficient mice. Circulation 112:2677-2685.
-
(2005)
Circulation
, vol.112
, pp. 2677-2685
-
-
Matsuno, K.1
Yamada, H.2
Iwata, K.3
Jin, D.4
Katsuyama, M.5
Matsuki, M.6
Takai, S.7
Yamanishi, K.8
Miyazaki, M.9
Matsubara, H.10
Yabe-Nishimura, C.11
-
21
-
-
37149016394
-
Localization of S100A8 and S100A9 expressing neutrophils to spinal cord during peripheral tissue inflammation
-
Mitchell K, Yang HY, Tessier PA, Muhly WT, Swaim WD, Szalayova I, Keller JM, Mezey E, Iadarola MJ (2008) Localization of S100A8 and S100A9 expressing neutrophils to spinal cord during peripheral tissue inflammation. Pain 134:216-231.
-
(2008)
Pain
, vol.134
, pp. 216-231
-
-
Mitchell, K.1
Yang, H.Y.2
Tessier, P.A.3
Muhly, W.T.4
Swaim, W.D.5
Szalayova, I.6
Keller, J.M.7
Mezey, E.8
Iadarola, M.J.9
-
22
-
-
4344647033
-
Superoxide-mediated nitration of spinal manganese superoxide dismutase: A novel pathway in N-methyl-D-aspartate-mediated hyperalgesia
-
Muscoli C, Mollace V, Wheatley J, Masini E, Ndengele M, Wang ZQ, Salvemini D (2004) Superoxide-mediated nitration of spinal manganese superoxide dismutase: a novel pathway in N-methyl-D-aspartate-mediated hyperalgesia. Pain 111:96-103.
-
(2004)
Pain
, vol.111
, pp. 96-103
-
-
Muscoli, C.1
Mollace, V.2
Wheatley, J.3
Masini, E.4
Ndengele, M.5
Wang, Z.Q.6
Salvemini, D.7
-
23
-
-
0037134417
-
Direct phosphorylation of capsaicin receptor VR1 by protein kinase Cepsilon and identification of two target serine residues
-
Numazaki M, Tominaga T, Toyooka H, Tominaga M (2002) Direct phosphorylation of capsaicin receptor VR1 by protein kinase Cepsilon and identification of two target serine residues. J Biol Chem 277:13375-13378.
-
(2002)
J Biol Chem
, vol.277
, pp. 13375-13378
-
-
Numazaki, M.1
Tominaga, T.2
Toyooka, H.3
Tominaga, M.4
-
24
-
-
21944443712
-
Fast modulation of heat-activated ionic current by proinflammatory interleukin 6 in rat sensory neurons
-
Obreja O, Biasio W, Andratsch M, Lips KS, Rathee PK, Ludwig A, Rose-John S, Kress M (2005) Fast modulation of heat-activated ionic current by proinflammatory interleukin 6 in rat sensory neurons. Brain 128:1634-1641.
-
(2005)
Brain
, vol.128
, pp. 1634-1641
-
-
Obreja, O.1
Biasio, W.2
Andratsch, M.3
Lips, K.S.4
Rathee, P.K.5
Ludwig, A.6
Rose-John, S.7
Kress, M.8
-
25
-
-
33750399000
-
Potentiation of transient receptor potential V1 functions by the activation of metabotropic 5-HT receptors in rat primary sensory neurons
-
Ohta T, Ikemi Y, Murakami M, Imagawa T, Otsuguro K, Ito S (2006) Potentiation of transient receptor potential V1 functions by the activation of metabotropic 5-HT receptors in rat primary sensory neurons. J Physiol 576:809-822.
-
(2006)
J Physiol
, vol.576
, pp. 809-822
-
-
Ohta, T.1
Ikemi, Y.2
Murakami, M.3
Imagawa, T.4
Otsuguro, K.5
Ito, S.6
-
26
-
-
0037144453
-
Protein kinase Ca is required for vanilloid receptor 1 activation
-
Olah Z, Karai L, Iadarola MJ (2002) Protein kinase Ca is required for vanilloid receptor 1 activation. J Biol Chem 277:35752-35759.
-
(2002)
J Biol Chem
, vol.277
, pp. 35752-35759
-
-
Olah, Z.1
Karai, L.2
Iadarola, M.J.3
-
27
-
-
29144460625
-
Essential role of Rac1/NADPH oxidase in nerve growth factor induction of TRPV1 expression
-
Puntambekar P, Mukherjea D, Jajoo S, Ramkumar V (2005) Essential role of Rac1/NADPH oxidase in nerve growth factor induction of TRPV1 expression. J Neurochem 95:1689-1703.
-
(2005)
J Neurochem
, vol.95
, pp. 1689-1703
-
-
Puntambekar, P.1
Mukherjea, D.2
Jajoo, S.3
Ramkumar, V.4
-
28
-
-
0036616952
-
PKA/AKAP/VR-1 module: A common link of Gs-mediated signaling to thermal hyperalgesia
-
Rathee PK, Distler C, Obreja O, Neuhuber W, Wang GK, Wang SY, Nau C, Kress M (2002) PKA/AKAP/VR-1 module: a common link of Gs-mediated signaling to thermal hyperalgesia. J Neurosci 22:4740-4745.
-
(2002)
J Neurosci
, vol.22
, pp. 4740-4745
-
-
Rathee, P.K.1
Distler, C.2
Obreja, O.3
Neuhuber, W.4
Wang, G.K.5
Wang, S.Y.6
Nau, C.7
Kress, M.8
-
29
-
-
0029952391
-
Evidence of peroxynitrite involvement in the carrageenan-induced rat paw edema
-
Salvemini D, Wang ZQ, Bourdon DM, Stern MK, Currie MG, Manning PT (1996) Evidence of peroxynitrite involvement in the carrageenan-induced rat paw edema. Eur J Pharmacol 303:217-220.
-
(1996)
Eur J Pharmacol
, vol.303
, pp. 217-220
-
-
Salvemini, D.1
Wang, Z.Q.2
Bourdon, D.M.3
Stern, M.K.4
Currie, M.G.5
Manning, P.T.6
-
30
-
-
1642499178
-
Synthesis, localization and externalization of galectin-1 in mature dorsal root ganglion neurons and Schwann cells
-
Sango K, Tokashiki A, Ajiki K, Horie M, Kawano H, Watabe K, Horie H, Kadoya T (2004) Synthesis, localization and externalization of galectin-1 in mature dorsal root ganglion neurons and Schwann cells. Eur J Neurosci 19:55-64.
-
(2004)
Eur J Neurosci
, vol.19
, pp. 55-64
-
-
Sango, K.1
Tokashiki, A.2
Ajiki, K.3
Horie, M.4
Kawano, H.5
Watabe, K.6
Horie, H.7
Kadoya, T.8
-
31
-
-
50249139609
-
Oxidative stress in the spinal cord is an important contributor in capsaicin-induced mechanical secondary hyperalgesia in mice
-
in press
-
Schwartz ES, Lee I, Chung K, Chung JM (2008) Oxidative stress in the spinal cord is an important contributor in capsaicin-induced mechanical secondary hyperalgesia in mice. Pain, in press.
-
(2008)
Pain
-
-
Schwartz, E.S.1
Lee, I.2
Chung, K.3
Chung, J.M.4
-
32
-
-
26044457052
-
Expression of NOX1, a superoxide-generating NADPH oxidase, in colon cancer and inflammatory bowel disease
-
Szanto I, Rubbia-Brandt L, Kiss P, Steger K, Banfi B, Kovari E, Herrmann F, Hadengue A, Krause KH (2005) Expression of NOX1, a superoxide-generating NADPH oxidase, in colon cancer and inflammatory bowel disease. J Pathol 207:164-176.
-
(2005)
J Pathol
, vol.207
, pp. 164-176
-
-
Szanto, I.1
Rubbia-Brandt, L.2
Kiss, P.3
Steger, K.4
Banfi, B.5
Kovari, E.6
Herrmann, F.7
Hadengue, A.8
Krause, K.H.9
-
33
-
-
0034194051
-
Allodynia and hyperalgesia induced by herpes simplex virus type-1 infection in mice
-
Takasaki I, Andoh T, Shiraki K, Kuraishi Y (2000) Allodynia and hyperalgesia induced by herpes simplex virus type-1 infection in mice. Pain 86:95-101.
-
(2000)
Pain
, vol.86
, pp. 95-101
-
-
Takasaki, I.1
Andoh, T.2
Shiraki, K.3
Kuraishi, Y.4
-
34
-
-
0002940182
-
Animal models of analgesia
-
Dickenson A, Besson JM, eds, pp, Berlin: Springer
-
Tjolsen T, Hole K (1992) Animal models of analgesia. In: The pharmacology of pain (Dickenson A, Besson JM, eds), pp 1-20. Berlin: Springer.
-
(1992)
The pharmacology of pain
, pp. 1-20
-
-
Tjolsen, T.1
Hole, K.2
-
35
-
-
0032169804
-
The cloned capsaicin receptor integrates multiple pain-producing stimuli
-
Tominaga M, Caterina MJ, Malmberg AB, Rosen TA, Gilbert H, Skinner K, Raumann BE, Basbaum AI, Julius D (1998) The cloned capsaicin receptor integrates multiple pain-producing stimuli. Neuron 21:531-543.
-
(1998)
Neuron
, vol.21
, pp. 531-543
-
-
Tominaga, M.1
Caterina, M.J.2
Malmberg, A.B.3
Rosen, T.A.4
Gilbert, H.5
Skinner, K.6
Raumann, B.E.7
Basbaum, A.I.8
Julius, D.9
-
36
-
-
2442648975
-
A newly identified role for superoxide in inflammatory pain
-
Wang ZQ, Porreca F, Cuzzocrea S, Galen K, Lightfoot R, Masini E, Muscoli C, Mollace V, Ndengele M, Ischiropoulos H, Salvemini D (2004) A newly identified role for superoxide in inflammatory pain. J Pharmacol Exp Ther 309:869-878.
-
(2004)
J Pharmacol Exp Ther
, vol.309
, pp. 869-878
-
-
Wang, Z.Q.1
Porreca, F.2
Cuzzocrea, S.3
Galen, K.4
Lightfoot, R.5
Masini, E.6
Muscoli, C.7
Mollace, V.8
Ndengele, M.9
Ischiropoulos, H.10
Salvemini, D.11
-
37
-
-
0030840882
-
Evidence for the involvement of spinal cord glia in subcutaneous formalin induced hyperalgesia in the rat
-
Watkins LR, Martin D, Ulrich P, Tracey KJ, Maier SF (1997) Evidence for the involvement of spinal cord glia in subcutaneous formalin induced hyperalgesia in the rat. Pain 71:225-235.
-
(1997)
Pain
, vol.71
, pp. 225-235
-
-
Watkins, L.R.1
Martin, D.2
Ulrich, P.3
Tracey, K.J.4
Maier, S.F.5
-
38
-
-
0036522967
-
Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease
-
Wu DC, Jackson-Lewis V, Vila M, Tieu K, Teismann P, Vadseth C, Choi DK, Ischiropoulos H, Przedborski S (2002) Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease. J Neurosci 22:1763-1771.
-
(2002)
J Neurosci
, vol.22
, pp. 1763-1771
-
-
Wu, D.C.1
Jackson-Lewis, V.2
Vila, M.3
Tieu, K.4
Teismann, P.5
Vadseth, C.6
Choi, D.K.7
Ischiropoulos, H.8
Przedborski, S.9
-
39
-
-
33747047814
-
The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice
-
Wu DC, Ré DB, Nagai M, Ischiropoulos H, Przedborski S (2006) The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice. Proc Natl Acad Sci U S A 103:12132-12137.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 12132-12137
-
-
Wu, D.C.1
Ré, D.B.2
Nagai, M.3
Ischiropoulos, H.4
Przedborski, S.5
-
40
-
-
33750257552
-
Nitric oxide activates TRP channels by cysteine S-nitrosylation
-
Yoshida T, Inoue R, Morii T, Takahashi N, Yamamoto S, Hara Y, Tominaga M, Shimizu S, Sato Y, Mori Y (2006) Nitric oxide activates TRP channels by cysteine S-nitrosylation. Nat Chem Biol 2:596-607.
-
(2006)
Nat Chem Biol
, vol.2
, pp. 596-607
-
-
Yoshida, T.1
Inoue, R.2
Morii, T.3
Takahashi, N.4
Yamamoto, S.5
Hara, Y.6
Tominaga, M.7
Shimizu, S.8
Sato, Y.9
Mori, Y.10
-
41
-
-
15444377583
-
A proinflammatory chemokine, CCL3, sensitizes the heat- and capsaicin-gated ion channel TRPV1
-
Zhang N, Inan S, Cowan A, Sun R, Wang JM, Rogers TJ, Caterina M, Oppenheim JJ (2005) A proinflammatory chemokine, CCL3, sensitizes the heat- and capsaicin-gated ion channel TRPV1. Proc Natl Acad Sci U S A 102:4536-4541.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 4536-4541
-
-
Zhang, N.1
Inan, S.2
Cowan, A.3
Sun, R.4
Wang, J.M.5
Rogers, T.J.6
Caterina, M.7
Oppenheim, J.J.8
|