Concurrent spinal infusion of MK801 blocks spinal tolerance and dependence induced by chronic intrathecal morphine in the rat

Anesthesiology

Volumn 84, Issue 5, 1996, Pages 1177-1188

  Dunbar, Stuart ^a   Yaksh, Tony L ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NONE

Author keywords

Analgesics, narcotic: dependence; morphine; spinal; tolerance; Receptors: N methyl D aspartate

Indexed keywords

DIZOCILPINE; MORPHINE SULFATE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NALOXONE; OPIATE RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; DRUG POTENTIATION; DRUG WITHDRAWAL; HOT PLATE TEST; INTRAPERITONEAL DRUG ADMINISTRATION; INTRATHECAL DRUG ADMINISTRATION; MALE; MORPHINE ADDICTION; MORPHINE TOLERANCE; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL ANESTHESIA; WITHDRAWAL SYNDROME;

ANALGESICS, OPIOID; ANIMALS; DIZOCILPINE MALEATE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; EXCITATORY AMINO ACID ANTAGONISTS; MALE; MORPHINE; MORPHINE DEPENDENCE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; SPINAL CORD;

EID: 0029864791     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199605000-00020     Document Type: Article

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