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Volumn 575, Issue 2, 2006, Pages 555-571

Protease-activated receptor 2 sensitizes TRPV1 by protein kinase Cε- and A-dependent mechanisms in rats and mice

Author keywords

[No Author keywords available]

Indexed keywords

CAPSAICIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; PHOSPHOLIPASE C BETA1; PROTEIN KINASE C EPSILON; PROTEINASE ACTIVATED RECEPTOR 2; PROTON; VANILLOID RECEPTOR 1; CALCIUM ION; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; PHOSPHOLIPASE C BETA; PROTEIN KINASE C INHIBITOR;

EID: 33747227271     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2006.111534     Document Type: Article
Times cited : (241)

References (59)
  • 2
    • 0034659718 scopus 로고    scopus 로고
    • Chronic hypersensitivity for inflammatory nociceptor sensitization mediated by the epsilon isozyme of protein kinase C
    • Aley KO, Messing RO, Mochly-Rosen D & Levine JD (2000). Chronic hypersensitivity for inflammatory nociceptor sensitization mediated by the epsilon isozyme of protein kinase C. J Neurosci 20, 4680-4685.
    • (2000) J Neurosci , vol.20 , pp. 4680-4685
    • Aley, K.O.1    Messing, R.O.2    Mochly-Rosen, D.3    Levine, J.D.4
  • 4
    • 0028202124 scopus 로고
    • ATP closes a potassium and opens a cationic conductance through different receptors in neurons of guinea pig submucous plexus
    • Barajas-Lopez C, Espinosa-Luna R & Gerzanich V (1994). ATP closes a potassium and opens a cationic conductance through different receptors in neurons of guinea pig submucous plexus. J Pharmacol Exp Ther 268, 1397-1402.
    • (1994) J Pharmacol Exp Ther , vol.268 , pp. 1397-1402
    • Barajas-Lopez, C.1    Espinosa-Luna, R.2    Gerzanich, V.3
  • 5
    • 0037104657 scopus 로고    scopus 로고
    • cAMP-dependent protein kinase regulates desensitization of the capsaicin receptor (VR1) by direct phosphorylation
    • Bhave G, Zhu W, Wang H, Brasier DJ, Oxford GS & Gereau RW 4th (2002). cAMP-dependent protein kinase regulates desensitization of the capsaicin receptor (VR1) by direct phosphorylation. Neuron 35, 721-731.
    • (2002) Neuron , vol.35 , pp. 721-731
    • Bhave, G.1    Zhu, W.2    Wang, H.3    Brasier, D.J.4    Oxford, G.S.5    Gereau IV, R.W.6
  • 6
    • 0029786481 scopus 로고    scopus 로고
    • Mechanisms of desensitization and resensitization of proteinase-activated receptor-2
    • Bohm SK, Khitin LM, Grady EF, Aponte G, Payan DG & Bunnett NW (1996). Mechanisms of desensitization and resensitization of proteinase-activated receptor-2. J Biol Chem 271, 22003-22016.
    • (1996) J Biol Chem , vol.271 , pp. 22003-22016
    • Bohm, S.K.1    Khitin, L.M.2    Grady, E.F.3    Aponte, G.4    Payan, D.G.5    Bunnett, N.W.6
  • 7
    • 0034624973 scopus 로고    scopus 로고
    • Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa
    • Camerer E, Huang W & Coughlin SR (2000). Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa. Proc Natl Acad Sci U S A 97, 5255-5260.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 5255-5260
    • Camerer, E.1    Huang, W.2    Coughlin, S.R.3
  • 11
    • 0037446646 scopus 로고    scopus 로고
    • Proteinase-activated receptor-2-induced colonic inflammation in mice: Possible involvement of afferent neurons, nitric oxide, and paracellular permeability
    • Cenac N, Garcia-Villar R, Ferrier L, Larauche M, Vergnolle N, Bunnett NW, Coelho AM, Fioramonti J & Bueno L (2003). Proteinase-activated receptor-2-induced colonic inflammation in mice: Possible involvement of afferent neurons, nitric oxide, and paracellular permeability. J Immunol 170, 4296-4300.
    • (2003) J Immunol , vol.170 , pp. 4296-4300
    • Cenac, N.1    Garcia-Villar, R.2    Ferrier, L.3    Larauche, M.4    Vergnolle, N.5    Bunnett, N.W.6    Coelho, A.M.7    Fioramonti, J.8    Bueno, L.9
  • 12
    • 0033166535 scopus 로고    scopus 로고
    • Specific involvement of PKC-epsilon in sensitization of the neuronal response to painful heat
    • Cesare P, Dekker LV, Sardini A, Parker PJ & McNaughton PA (1999). Specific involvement of PKC-epsilon in sensitization of the neuronal response to painful heat. Neuron 23, 617-624.
    • (1999) Neuron , vol.23 , pp. 617-624
    • Cesare, P.1    Dekker, L.V.2    Sardini, A.3    Parker, P.J.4    McNaughton, P.A.5
  • 13
  • 14
    • 33645509877 scopus 로고    scopus 로고
    • Differential regulation of endothelial exocytosis of P-selectin and von Willebrand factor by protease-activated receptors and cAMP
    • Cleator JH, Zhu WQ, Vaughan DE & Hamm HE (2006). Differential regulation of endothelial exocytosis of P-selectin and von Willebrand factor by protease-activated receptors and cAMP. Blood 107, 2736-2744.
    • (2006) Blood , vol.107 , pp. 2736-2744
    • Cleator, J.H.1    Zhu, W.Q.2    Vaughan, D.E.3    Hamm, H.E.4
  • 15
    • 0036207250 scopus 로고    scopus 로고
    • Proteinases and proteinase-activated receptor 2: A possible role to promote visceral hyperalgesia in rats
    • Coelho AM, Vergnolle N, Guiard B, Fioramonti J & Bueno L (2002). Proteinases and proteinase-activated receptor 2: A possible role to promote visceral hyperalgesia in rats. Gastroenterology 122, 1035-1047.
    • (2002) Gastroenterology , vol.122 , pp. 1035-1047
    • Coelho, A.M.1    Vergnolle, N.2    Guiard, B.3    Fioramonti, J.4    Bueno, L.5
  • 17
    • 1842791710 scopus 로고    scopus 로고
    • Trypsin IV, a novel agonist of protease-activated receptors 2 and 4
    • Cottrell GS, Amadesi S, Grady EF & Bunnett NW (2004). Trypsin IV, a novel agonist of protease-activated receptors 2 and 4. J Biol Chem 279, 13532-13539.
    • (2004) J Biol Chem , vol.279 , pp. 13532-13539
    • Cottrell, G.S.1    Amadesi, S.2    Grady, E.F.3    Bunnett, N.W.4
  • 18
    • 2442468123 scopus 로고    scopus 로고
    • Proteinase-activated receptor 2-mediated potentiation of transient receptor potential vanilloid subfamily 1 activity reveals a mechanism for proteinase-induced inflammatory pain
    • Dai Y, Moriyama T, Higashi T, Togashi K, Kobayashi K, Yamanaka H, Tominaga M & Noguchi K (2004). Proteinase-activated receptor 2-mediated potentiation of transient receptor potential vanilloid subfamily 1 activity reveals a mechanism for proteinase-induced inflammatory pain. J Neurosci 24, 4293-4299.
    • (2004) J Neurosci , vol.24 , pp. 4293-4299
    • Dai, Y.1    Moriyama, T.2    Higashi, T.3    Togashi, K.4    Kobayashi, K.5    Yamanaka, H.6    Tominaga, M.7    Noguchi, K.8
  • 20
    • 0034689003 scopus 로고    scopus 로고
    • Beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2
    • DeFea KA, Zalevsky J, Thoma MS, Dery O, Mullins RD & Bunnett NW (2000). beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2. J Cell Biol 148, 1267-1281.
    • (2000) J Cell Biol , vol.148 , pp. 1267-1281
    • DeFea, K.A.1    Zalevsky, J.2    Thoma, M.S.3    Dery, O.4    Mullins, R.D.5    Bunnett, N.W.6
  • 21
    • 0039843091 scopus 로고    scopus 로고
    • Trafficking of proteinase-activated receptor-2 and beta-arrestin-1 tagged with green fluorescent protein. Beta-arrestin-dependent endocytosis of a proteinase receptor
    • Dery O, Thoma MS, Wong H, Grady EF & Bunnett NW (1999). Trafficking of proteinase-activated receptor-2 and beta-arrestin-1 tagged with green fluorescent protein. Beta-arrestin-dependent endocytosis of a proteinase receptor. J Biol Chem 274, 18524-18535.
    • (1999) J Biol Chem , vol.274 , pp. 18524-18535
    • Dery, O.1    Thoma, M.S.2    Wong, H.3    Grady, E.F.4    Bunnett, N.W.5
  • 22
    • 0036196195 scopus 로고    scopus 로고
    • Intracellular transport mechanisms of signal transducers
    • Dorn GW 2nd & Mochly-Rosen D (2002). Intracellular transport mechanisms of signal transducers. Annu Rev Physiol 64, 407-429.
    • (2002) Annu Rev Physiol , vol.64 , pp. 407-429
    • Dorn II, G.W.1    Mochly-Rosen, D.2
  • 25
    • 0036758636 scopus 로고    scopus 로고
    • Prostaglandin and protein kinase A-dependent modulation of vanilloid receptor function by metabotropic glutamate receptor 5: Potential mechanism for thermal hyperalgesia
    • Hu HJ, Bhave G & Gereau RW 4th (2002). Prostaglandin and protein kinase A-dependent modulation of vanilloid receptor function by metabotropic glutamate receptor 5: Potential mechanism for thermal hyperalgesia. J Neurosci 22, 7444-7452.
    • (2002) J Neurosci , vol.22 , pp. 7444-7452
    • Hu, H.J.1    Bhave, G.2    Gereau IV, R.W.3
  • 26
    • 21544452743 scopus 로고    scopus 로고
    • Epac mediates a cAMP-to-PKC signaling in inflammatory pain: An isolectin B4(+) neuron-specific mechanism
    • Hucho TB, Dina OA & Levine JD (2005). Epac mediates a cAMP-to-PKC signaling in inflammatory pain: An isolectin B4(+) neuron-specific mechanism. J Neurosci 25, 6119-6126.
    • (2005) J Neurosci , vol.25 , pp. 6119-6126
    • Hucho, T.B.1    Dina, O.A.2    Levine, J.D.3
  • 27
    • 18144412332 scopus 로고    scopus 로고
    • C-Cbl mediates ubiquitination, degradation, and down-regulation of human protease-activated receptor 2
    • Jacob C, Cottrell GS, Gehringer D, Schmidlin F, Grady EF & Bunnett NW (2005). C-Cbl mediates ubiquitination, degradation, and down-regulation of human protease-activated receptor 2. J Biol Chem 280, 16076-16087.
    • (2005) J Biol Chem , vol.280 , pp. 16076-16087
    • Jacob, C.1    Cottrell, G.S.2    Gehringer, D.3    Schmidlin, F.4    Grady, E.F.5    Bunnett, N.W.6
  • 28
    • 0035953151 scopus 로고    scopus 로고
    • Peripheral PAR-2 triggers thermal hyperalgesia and nociceptive responses in rats
    • Kawabata A, Kawao N, Kuroda R, Tanaka A, Itoh H & Nishikawa H (2001a). Peripheral PAR-2 triggers thermal hyperalgesia and nociceptive responses in rats. Neuroreport 12, 715-719.
    • (2001) Neuroreport , vol.12 , pp. 715-719
    • Kawabata, A.1    Kawao, N.2    Kuroda, R.3    Tanaka, A.4    Itoh, H.5    Nishikawa, H.6
  • 31
    • 0142243114 scopus 로고    scopus 로고
    • Stimulation of proteinase-activated receptor 2 excites jejunal afferent nerves in anaesthetised rats
    • Kirkup AJ, Jiang W, Bunnett NW & Grundy D (2003). Stimulation of proteinase-activated receptor 2 excites jejunal afferent nerves in anaesthetised rats. J Physiol 552, 589-601.
    • (2003) J Physiol , vol.552 , pp. 589-601
    • Kirkup, A.J.1    Jiang, W.2    Bunnett, N.W.3    Grundy, D.4
  • 33
    • 0031283176 scopus 로고    scopus 로고
    • Activation and recovery of the PGE2-mediated sensitization of the capsaicin response in rat sensory neurons
    • Lopshire JC & Nicol GD (1997). Activation and recovery of the PGE2-mediated sensitization of the capsaicin response in rat sensory neurons. J Neurophysiol 78, 3154-3164.
    • (1997) J Neurophysiol , vol.78 , pp. 3154-3164
    • Lopshire, J.C.1    Nicol, G.D.2
  • 34
    • 0032529562 scopus 로고    scopus 로고
    • The cAMP transduction cascade mediates the prostaglandin E2 enhancement of the capsaicin-elicited current in rat sensory neurons: Whole-cell and single-channel studies
    • Lopshire JC & Nicol GD (1998). The cAMP transduction cascade mediates the prostaglandin E2 enhancement of the capsaicin-elicited current in rat sensory neurons: Whole-cell and single-channel studies. J Neurosci 18, 6081-6092.
    • (1998) J Neurosci , vol.18 , pp. 6081-6092
    • Lopshire, J.C.1    Nicol, G.D.2
  • 35
    • 0030841539 scopus 로고    scopus 로고
    • Diminished inflammation and nociceptive pain with preservation of neuropathic pain in mice with a targeted mutation of the type I regulatory subunit of cAMP-dependent protein kinase
    • Malmberg AB, Brandon EP, Idzerda RL, Liu H, McKnight GS & Basbaum AI (1997). Diminished inflammation and nociceptive pain with preservation of neuropathic pain in mice with a targeted mutation of the type I regulatory subunit of cAMP-dependent protein kinase. J Neurosci 17, 7462-7470.
    • (1997) J Neurosci , vol.17 , pp. 7462-7470
    • Malmberg, A.B.1    Brandon, E.P.2    Idzerda, R.L.3    Liu, H.4    McKnight, G.S.5    Basbaum, A.I.6
  • 36
    • 0346118925 scopus 로고    scopus 로고
    • Desensitization of capsaicin-activated currents in the vanilloid receptor TRPV1 is decreased by the cyclic AMP-dependent protein kinase pathway
    • Mohapatra DP & Nau C (2003). Desensitization of capsaicin-activated currents in the vanilloid receptor TRPV1 is decreased by the cyclic AMP-dependent protein kinase pathway. J Biol Chem 278, 50080-50090.
    • (2003) J Biol Chem , vol.278 , pp. 50080-50090
    • Mohapatra, D.P.1    Nau, C.2
  • 38
    • 2942614748 scopus 로고    scopus 로고
    • Regulated exocytosis contributes to protein kinase C potentiation of vanilloid receptor activity
    • Morenilla-Palao C, Planells-Cases R, Garcia-Sanz N & Ferrer-Montiel A (2004). Regulated exocytosis contributes to protein kinase C potentiation of vanilloid receptor activity. J Biol Chem 279, 25665-25672.
    • (2004) J Biol Chem , vol.279 , pp. 25665-25672
    • Morenilla-Palao, C.1    Planells-Cases, R.2    Garcia-Sanz, N.3    Ferrer-Montiel, A.4
  • 39
    • 20344405454 scopus 로고    scopus 로고
    • Trypsin stimulates the phosphorylation of p42,44 mitogen-activated protein kinases via the proteinase-activated receptor-2 and protein kinase C epsilon in human cultured prostate stromal cells
    • Myatt A & Hill SJ (2005). Trypsin stimulates the phosphorylation of p42,44 mitogen-activated protein kinases via the proteinase-activated receptor-2 and protein kinase C epsilon in human cultured prostate stromal cells. Prostate 64, 175-185.
    • (2005) Prostate , vol.64 , pp. 175-185
    • Myatt, A.1    Hill, S.J.2
  • 41
    • 0037134417 scopus 로고    scopus 로고
    • Direct phosphorylation of capsaicin receptor VR1 by protein kinase C epsilon and identification of two target serine residues
    • Numazaki M, Tominaga T, Toyooka H & Tominaga M (2002). Direct phosphorylation of capsaicin receptor VR1 by protein kinase C epsilon and identification of two target serine residues. J Biol Chem 277, 13375-13378.
    • (2002) J Biol Chem , vol.277 , pp. 13375-13378
    • Numazaki, M.1    Tominaga, T.2    Toyooka, H.3    Tominaga, M.4
  • 42
    • 1642279517 scopus 로고    scopus 로고
    • Protease-activated receptors: Contribution to physiology and disease
    • Ossovskaya VS & Bunnett NW (2004). Protease-activated receptors: contribution to physiology and disease. Physiol Rev 84, 579-621.
    • (2004) Physiol Rev , vol.84 , pp. 579-621
    • Ossovskaya, V.S.1    Bunnett, N.W.2
  • 43
    • 11144271468 scopus 로고    scopus 로고
    • Chronic hyperalgesic priming in the rat involves a novel interaction between cAMP and PKC epsilon second messenger pathways
    • Parada CA, Reichling DB & Levine JD (2005). Chronic hyperalgesic priming in the rat involves a novel interaction between cAMP and PKC epsilon second messenger pathways. Pain 113, 185-190.
    • (2005) Pain , vol.113 , pp. 185-190
    • Parada, C.A.1    Reichling, D.B.2    Levine, J.D.3
  • 44
    • 0034700494 scopus 로고    scopus 로고
    • Induction of vanilloid receptor channel activity by protein kinase C
    • Premkumar LS & Ahern GP (2000). Induction of vanilloid receptor channel activity by protein kinase C. Nature 408, 985-990.
    • (2000) Nature , vol.408 , pp. 985-990
    • Premkumar, L.S.1    Ahern, G.P.2
  • 45
    • 0037799198 scopus 로고    scopus 로고
    • A modular PIP2 binding site as a determinant of capsaicin receptor sensitivity
    • Prescott ED & Julius D (2003). A modular PIP2 binding site as a determinant of capsaicin receptor sensitivity. Science 300, 1284-1288.
    • (2003) Science , vol.300 , pp. 1284-1288
    • Prescott, E.D.1    Julius, D.2
  • 47
    • 4544248747 scopus 로고    scopus 로고
    • G protein-coupled receptor-mediated phosphorylation of the activation loop of protein kinase D: Dependence on plasma membrane translocation and protein kinase C epsilon
    • Rey O, Reeve JR Jr, Zhukova E, Sinnett-Smith J & Rozengurt E (2004). G protein-coupled receptor-mediated phosphorylation of the activation loop of protein kinase D: Dependence on plasma membrane translocation and protein kinase C epsilon. J Biol Chem 279, 34361-34372.
    • (2004) J Biol Chem , vol.279 , pp. 34361-34372
    • Rey, O.1    Reeve Jr., J.R.2    Zhukova, E.3    Sinnett-Smith, J.4    Rozengurt, E.5
  • 50
    • 0033520487 scopus 로고    scopus 로고
    • In vivo protein transduction: Delivery of a biologically active protein into the mouse
    • Schwarze SR, Ho A, Vocero-Akbani A & Dowdy SF (1999). In vivo protein transduction: Delivery of a biologically active protein into the mouse. Science 285, 1569-1572.
    • (1999) Science , vol.285 , pp. 1569-1572
    • Schwarze, S.R.1    Ho, A.2    Vocero-Akbani, A.3    Dowdy, S.F.4
  • 51
    • 0042334898 scopus 로고    scopus 로고
    • The proteinase-activated receptor-2 mediates phagocytosis in a Rho-dependent manner in human keratinocytes
    • Scott G, Leopardi S, Parker L, Babiarz L, Seiberg M & Han R (2003). The proteinase-activated receptor-2 mediates phagocytosis in a Rho-dependent manner in human keratinocytes. J Invest Dermatol 121, 529-541.
    • (2003) J Invest Dermatol , vol.121 , pp. 529-541
    • Scott, G.1    Leopardi, S.2    Parker, L.3    Babiarz, L.4    Seiberg, M.5    Han, R.6
  • 53
    • 0035810934 scopus 로고    scopus 로고
    • Potentiation of capsaicin receptor activity by metabotropic ATP receptors as a possible mechanism for ATP-evoked pain and hyperalgesia
    • Tominaga M, Wada M & Masu M (2001). Potentiation of capsaicin receptor activity by metabotropic ATP receptors as a possible mechanism for ATP-evoked pain and hyperalgesia. Proc Natl Acad Sci U S A 98, 6951-6956.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 6951-6956
    • Tominaga, M.1    Wada, M.2    Masu, M.3
  • 55
    • 0035425705 scopus 로고    scopus 로고
    • Protein kinase C activation potentiates gating of the vanilloid receptor VR1 by capsaicin, protons, heat and anandamide
    • Vellani V, Mapplebeck S, Moriondo A, Davis JB & McNaughton PA (2001). Protein kinase C activation potentiates gating of the vanilloid receptor VR1 by capsaicin, protons, heat and anandamide. J Physiol 534, 813-825.
    • (2001) J Physiol , vol.534 , pp. 813-825
    • Vellani, V.1    Mapplebeck, S.2    Moriondo, A.3    Davis, J.B.4    McNaughton, P.A.5
  • 58
    • 29244484493 scopus 로고    scopus 로고
    • NGF rapidly increases membrane expression of TRPV1 heat-gated ion channels
    • Zhang X, Huang J & McNaughton PA (2005). NGF rapidly increases membrane expression of TRPV1 heat-gated ion channels. EMBO J 24, 4211-4223.
    • (2005) EMBO J , vol.24 , pp. 4211-4223
    • Zhang, X.1    Huang, J.2    McNaughton, P.A.3


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