Chronic morphine induces downregulation of spinal glutamate transporters: Implications in morphine tolerance and abnormal pain sensitivity

Journal of Neuroscience

Volumn 22, Issue 18, 2002, Pages 8312-8323

  Mao, Jianren ^a   Sung, Backil ^a   Ji, Ru Rong ^a   Lim, Grewo ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Glutamate transporter; Hyperalgesia; NMDA; Opioid; PDC; Riluzole; Tolerance

Indexed keywords

DIZOCILPINE; GLUTAMATE TRANSPORTER; GLUTAMATE TRANSPORTER INHIBITOR; MORPHINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NALOXONE; OPIATE RECEPTOR; PYRROLIDINE 2,4 DICARBOXYLATE; RILUZOLE; UNCLASSIFIED DRUG;

ANALGESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTINUOUS INFUSION; DISEASE ASSOCIATION; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DRUG TOLERANCE; HOMEOSTASIS; HYPERALGESIA; INHIBITION KINETICS; LONG TERM EXPOSURE; MALE; MORPHINE ADDICTION; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; RAT; SPINAL CORD; SPINAL CORD DORSAL HORN;

EID: 0037107189     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-18-08312.2002     Document Type: Article

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