Glial TLR4 receptor as new target to treat neuropathic pain: Efficacy of a new receptor antagonist in a model of peripheral nerve injury in mice

GLIA

Volumn 56, Issue 12, 2008, Pages 1312-1319

  Bettoni, Isabella ^a   Comelli, Francesca ^a   Rossini, Clara ^a   Granucci, Francesca ^a   Giagnoni, Gabriella ^a   Peri, Francesco ^a   Costa, Barbara ^a  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

Author keywords

Cytokines; Microglia; Neuropathic pain; Spinal cord; TLR4 receptor

Indexed keywords

FP 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MONOSACCHARIDE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; GLIA CELL; HYPERALGESIA; KNOCKOUT MOUSE; MALE; MOUSE; NEUROPATHIC PAIN; NONHUMAN; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; RECEPTOR BLOCKING; SCIATIC NERVE; SIGNAL TRANSDUCTION; SPINAL CORD; UPREGULATION;

ANIMALS; DISEASE MODELS, ANIMAL; DRUG DELIVERY SYSTEMS; HYPERALGESIA; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURALGIA; NEUROGLIA; PAIN MEASUREMENT; PERIPHERAL NERVOUS SYSTEM DISEASES; PYRAZOLES; TOLL-LIKE RECEPTOR 4;

EID: 51349166320     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.20699     Document Type: Article

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