Spinal NADPH oxidase is a source of superoxide in the development of morphine-induced hyperalgesia and antinociceptive tolerance

Neuroscience Letters

Volumn 483, Issue 2, 2010, Pages 85-89

  Doyle, Tim ^a   Bryant, Leesa ^a   Muscoli, Carolina ^a,b,c   Cuzzocrea, Salvatore ^d   Esposito, Emanuela ^d   Chen, Zhoumou ^a   Salvemini, Daniela ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^c IRCCS SAN RAFFAELE PISANA   (Italy)

^d UNIVERSITY OF MESSINA   (Italy)

Author keywords

Morphine antinociceptive tolerance; NADPH oxidase; Peroxynitrite; Superoxide

Indexed keywords

APOCYNIN; DIPHENYLIODONIUM SALT; MORPHINE; PEROXYNITRITE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; HYPERALGESIA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPINAL CORD;

ANALGESICS, OPIOID; ANIMALS; DRUG TOLERANCE; HYPERALGESIA; MALE; MICE; MORPHINE; NADPH OXIDASE; SPINAL CORD; SUPEROXIDES;

EID: 77956188649     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.07.013     Document Type: Article

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