Characterization of SB-269970-A, a selective 5-HT7 receptor antagonist

British Journal of Pharmacology

Volumn 130, Issue 3, 2000, Pages 539-548

  Hagan, Jim J ^a   Price, Gary W ^a   Jeffrey, Phillip ^a   Deeks, Nigel J ^a   Stean, Tania ^a   Piper, David ^a   Smith, Martin I ^a   Upton, Neil ^a   Medhurst, Andrew D ^a   Middlemiss, Derek N ^a   Riley, Graham J ^a   Lovell, Peter J ^a   Bromidge, Steven M ^a   Thomas, David R ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

5 CT; Adenylyl cyclase; EEG; Guinea pig; Hypothermia; Rat; Receptor; SB 269970 A; Sleep

Indexed keywords

3,N DIMETHYL N [1 METHYL 3 (4 METHYL 1 PIPERIDINYL)PROPYL]BENZENESULFONAMIDE; ADENYLATE CYCLASE; CLOZAPINE; KETANSERIN; MESULERGINE; METERGOLINE; METITEPINE; PINDOLOL; SB 269970 A; SEROTONIN 7 RECEPTOR; SEROTONIN ANTAGONIST; TRYPTAMINE DERIVATIVE; UNCLASSIFIED DRUG;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CORTEX; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG CLEARANCE; DRUG PENETRATION; DRUG POTENCY; DRUG RECEPTOR BINDING; ENZYME ACTIVITY; GUINEA PIG; HIPPOCAMPUS; HYPOTHALAMUS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR AFFINITY; REM SLEEP; TESTIS; THALAMUS;

EID: 0034070287     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703357     Document Type: Article

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