A 5-HT2C Receptor Promoter Polymorphism (HTR2C -759C/T) Is Associated with Obesity in Women, and with Resistance to Weight Loss in Heterozygotes

American Journal of Medical Genetics - Neuropsychiatric Genetics

Volumn 126 B, Issue 1, 2004, Pages 124-127

  Pooley, Edward C ^a   Fairburn, Christopher G ^a   Cooper, Zafra ^a   Sodhi, Monsheel S ^a   Cowen, Philip J ^a   Harrison, Paul J ^a,b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b WARNEFORD HOSPITAL   (United Kingdom)

Author keywords

Gender; Gene expression; Heterosis; mRNA; Nutrition; Serotonin receptor

Indexed keywords

ANTIOBESITY AGENT; NEUROLEPTIC AGENT; SEROTONIN 2C AGONIST; SEROTONIN 2C RECEPTOR; MESSENGER RNA; TRIACYLGLYCEROL;

ADULT; APPETITE; ARTICLE; BODY MASS; BODY WEIGHT; CONTROLLED STUDY; DRUG SCREENING; FEMALE; FRONTAL CORTEX; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HETEROSIS; HETEROZYGOTE; HUMAN; MAJOR CLINICAL STUDY; OBESITY; PHARMACOGENETICS; PRIORITY JOURNAL; PROMOTER REGION; RISK FACTOR; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT GAIN; WEIGHT REDUCTION; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; GENETICS; HOMOZYGOTE; METABOLISM; RANDOMIZED CONTROLLED TRIAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADULT; BODY WEIGHT; FEMALE; HETEROZYGOTE; HOMOZYGOTE; HUMANS; OBESITY; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); RECEPTOR, SEROTONIN, 5-HT2C; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RISK FACTORS; RNA, MESSENGER; TRIGLYCERIDES; WEIGHT LOSS;

EID: 1842434558     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.20143     Document Type: Article

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