Association of antipsychotic drug-induced weight gain with a 5-HT2C receptor gene polymorphism

Lancet

Volumn 359, Issue 9323, 2002, Pages 2086-2087

  Reynolds, Gavin P ^a   Zhang, Zhi Jun ^a,b   Zhang, Xiao Bin ^b  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORPROMAZINE; CLOZAPINE; FLUPHENAZINE; GENOMIC DNA; NEUROLEPTIC AGENT; RISPERIDONE; SEROTONIN 2C RECEPTOR; SULPIRIDE;

ADULT; ALLELE; ARTICLE; BODY MASS; CONTROLLED STUDY; DNA POLYMORPHISM; DRUG RECEPTOR BINDING; FEMALE; GENOTYPE; HEREDITY; HUMAN; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; SCHIZOPHRENIA; WEIGHT GAIN;

EID: 0037097014     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(02)08913-4     Document Type: Article

References (5)

1. Antipsychotic-induced weight gain: A comprehensive research synthesis
2. Eating disorder and epilepsy in mice lacking 5-HT2C serotonin receptors
3. Evaluation of a Cys23Ser mutation within the human 5-HT2C receptor gene: No evidence for an association of the mutant allele with obesity or underweight in children, adolescents and young adults
4. Genetic variants of the serotonin system and weight change during clozapine treatment
5. Identification of polymorphic loci in the promoter region of the serotonin 5HT2C receptor gene and their association with obesity and type II diabetes