-
2
-
-
34250020201
-
Hepatocellular carcinoma: Epidemiology and molecular carcinogenesis
-
H.B. El-Serag, and K.L. Rudolph Hepatocellular carcinoma: epidemiology and molecular carcinogenesis Gastroenterology 132 2007 2557 2576
-
(2007)
Gastroenterology
, vol.132
, pp. 2557-2576
-
-
El-Serag, H.B.1
Rudolph, K.L.2
-
3
-
-
75449094816
-
Obesity and nonalcoholic fatty liver disease: Biochemical, metabolic, and clinical implications
-
E. Fabbrini, S. Sullivan, and S. Klein Obesity and nonalcoholic fatty liver disease: biochemical, metabolic, and clinical implications Hepatology 51 2010 679 689
-
(2010)
Hepatology
, vol.51
, pp. 679-689
-
-
Fabbrini, E.1
Sullivan, S.2
Klein, S.3
-
4
-
-
34249746761
-
Pathogenesis of non-alcoholic steatohepatitis: Human data
-
J. Edmison, and A.J. McCullough Pathogenesis of non-alcoholic steatohepatitis: human data Clin Liver Dis 11 2007 75 104 ix
-
(2007)
Clin Liver Dis
, vol.11
, pp. 75-104
-
-
Edmison, J.1
McCullough, A.J.2
-
5
-
-
35948954244
-
Hepatic stellate cells: Protean, multifunctional, and enigmatic cells of the liver
-
S.L. Friedman Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver Physiol Rev 88 2008 125 172
-
(2008)
Physiol Rev
, vol.88
, pp. 125-172
-
-
Friedman, S.L.1
-
7
-
-
33847363203
-
Models of liver fibrosis: Exploring the dynamic nature of inflammation and repair in a solid organ
-
J.P. Iredale Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ J Clin Invest 117 2007 539 548
-
(2007)
J Clin Invest
, vol.117
, pp. 539-548
-
-
Iredale, J.P.1
-
8
-
-
39749170639
-
Myofibroblast-like cells and liver fibrogenesis: Emerging concepts in a rapidly moving scenario
-
M. Parola, F. Marra, and M. Pinzani Myofibroblast-like cells and liver fibrogenesis: emerging concepts in a rapidly moving scenario Mol Aspects Med 29 2008 58 66
-
(2008)
Mol Aspects Med
, vol.29
, pp. 58-66
-
-
Parola, M.1
Marra, F.2
Pinzani, M.3
-
9
-
-
3543098600
-
Liver fibrosis: From the bench to clinical targets
-
M. Pinzani, and K. Rombouts Liver fibrosis: from the bench to clinical targets Dig Liver Dis 36 2004 231 242
-
(2004)
Dig Liver Dis
, vol.36
, pp. 231-242
-
-
Pinzani, M.1
Rombouts, K.2
-
10
-
-
0034869459
-
Oxidative stress-related molecules and liver fibrosis
-
M. Parola, and G. Robino Oxidative stress-related molecules and liver fibrosis J Hepatol 35 2001 297 306
-
(2001)
J Hepatol
, vol.35
, pp. 297-306
-
-
Parola, M.1
Robino, G.2
-
11
-
-
33646867426
-
Mechanisms of liver injury. II. Mechanisms of neutrophil-induced liver cell injury during hepatic ischemia-reperfusion and other acute inflammatory conditions
-
H. Jaeschke Mechanisms of liver injury. II. Mechanisms of neutrophil-induced liver cell injury during hepatic ischemia-reperfusion and other acute inflammatory conditions Am J Physiol Gastrointest Liver Physiol 290 2006 G1083 G1088
-
(2006)
Am J Physiol Gastrointest Liver Physiol
, vol.290
-
-
Jaeschke, H.1
-
13
-
-
4043077961
-
Molecular mediators of hepatic steatosis and liver injury
-
J.D. Browning, and J.D. Horton Molecular mediators of hepatic steatosis and liver injury J Clin Invest 114 2004 147 152
-
(2004)
J Clin Invest
, vol.114
, pp. 147-152
-
-
Browning, J.D.1
Horton, J.D.2
-
14
-
-
54549111991
-
Oxidative and nitrosative stress and fibrogenic response
-
R. Urtasun, L. Conde delaRosa, and N. Nieto Oxidative and nitrosative stress and fibrogenic response Clin Liver Dis 12 2008 769 790 viii
-
(2008)
Clin Liver Dis
, vol.12
, pp. 769-790
-
-
Urtasun, R.1
Delarosa, C.L.2
Nieto, N.3
-
16
-
-
27644510537
-
Review article: Role of oxidative stress in the progression of non-alcoholic steatosis
-
E. Albano, E. Mottaran, G. Occhino, E. Reale, and M. Vidali Review article: role of oxidative stress in the progression of non-alcoholic steatosis Aliment Pharmacol Ther 22 Suppl. 2 2005 71 73
-
(2005)
Aliment Pharmacol Ther
, vol.22
, Issue.SUPPL. 2
, pp. 71-73
-
-
Albano, E.1
Mottaran, E.2
Occhino, G.3
Reale, E.4
Vidali, M.5
-
17
-
-
0029131271
-
Immune mechanisms of alcohol-induced liver disease
-
L.W. Klassen, D. Tuma, and M.F. Sorrell Immune mechanisms of alcohol-induced liver disease Hepatology 22 1995 355 357
-
(1995)
Hepatology
, vol.22
, pp. 355-357
-
-
Klassen, L.W.1
Tuma, D.2
Sorrell, M.F.3
-
18
-
-
0034901463
-
Hypoxia-inducible factor 1: Oxygen homeostasis and disease pathophysiology
-
G.L. Semenza Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology Trends Mol Med 7 2001 345 350
-
(2001)
Trends Mol Med
, vol.7
, pp. 345-350
-
-
Semenza, G.L.1
-
19
-
-
8344237449
-
Hydroxylation of HIF-1: Oxygen sensing at the molecular level
-
G.L. Semenza Hydroxylation of HIF-1: oxygen sensing at the molecular level Physiology (Bethesda) 19 2004 176 182
-
(2004)
Physiology (Bethesda)
, vol.19
, pp. 176-182
-
-
Semenza, G.L.1
-
20
-
-
40949142209
-
The role of hypoxia-inducible factors in tumorigenesis
-
E.B. Rankin, and A.J. Giaccia The role of hypoxia-inducible factors in tumorigenesis Cell Death Differ 15 2008 678 685
-
(2008)
Cell Death Differ
, vol.15
, pp. 678-685
-
-
Rankin, E.B.1
Giaccia, A.J.2
-
21
-
-
67650489215
-
Hypoxia-inducible factor-dependent production of profibrotic mediators by hypoxic hepatocytes
-
B.L. Copple, J.J. Bustamante, T.P. Welch, N.D. Kim, and J.O. Moon Hypoxia-inducible factor-dependent production of profibrotic mediators by hypoxic hepatocytes Liver Int 29 2009 1010 1021
-
(2009)
Liver Int
, vol.29
, pp. 1010-1021
-
-
Copple, B.L.1
Bustamante, J.J.2
Welch, T.P.3
Kim, N.D.4
Moon, J.O.5
-
22
-
-
34447317835
-
Proangiogenic cytokines as hypoxia-dependent factors stimulating migration of human hepatic stellate cells
-
E. Novo, S. Cannito, E. Zamara, L. Valfre di Bonzo, A. Caligiuri, and C. Cravanzola Proangiogenic cytokines as hypoxia-dependent factors stimulating migration of human hepatic stellate cells Am J Pathol 170 2007 1942 1953
-
(2007)
Am J Pathol
, vol.170
, pp. 1942-1953
-
-
Novo, E.1
Cannito, S.2
Zamara, E.3
Valfre Di Bonzo, L.4
Caligiuri, A.5
Cravanzola, C.6
-
23
-
-
32944478021
-
Upregulation of proinflammatory and proangiogenic cytokines by leptin in human hepatic stellate cells
-
S. Aleffi, I. Petrai, C. Bertolani, M. Parola, S. Colombatto, and E. Novo Upregulation of proinflammatory and proangiogenic cytokines by leptin in human hepatic stellate cells Hepatology 42 2005 1339 1348
-
(2005)
Hepatology
, vol.42
, pp. 1339-1348
-
-
Aleffi, S.1
Petrai, I.2
Bertolani, C.3
Parola, M.4
Colombatto, S.5
Novo, E.6
-
24
-
-
0033980284
-
Hypoxic stimulation of vascular endothelial growth factor expression in activated rat hepatic stellate cells
-
V. Ankoma-Sey, Y. Wang, and Z. Dai Hypoxic stimulation of vascular endothelial growth factor expression in activated rat hepatic stellate cells Hepatology 31 2000 141 148
-
(2000)
Hepatology
, vol.31
, pp. 141-148
-
-
Ankoma-Sey, V.1
Wang, Y.2
Dai, Z.3
-
25
-
-
1842426689
-
Regulatory role of vHL/HIF-1alpha in hypoxia-induced VEGF production in hepatic stellate cells
-
Y.Q. Wang, J.M. Luk, K. Ikeda, K. Man, A.C. Chu, and K. Kaneda Regulatory role of vHL/HIF-1alpha in hypoxia-induced VEGF production in hepatic stellate cells Biochem Biophys Res Commun 317 2004 358 362
-
(2004)
Biochem Biophys Res Commun
, vol.317
, pp. 358-362
-
-
Wang, Y.Q.1
Luk, J.M.2
Ikeda, K.3
Man, K.4
Chu, A.C.5
Kaneda, K.6
-
26
-
-
0042887507
-
Vascular endothelial growth factor and receptor interaction is a prerequisite for murine hepatic fibrogenesis
-
H. Yoshiji, S. Kuriyama, J. Yoshii, Y. Ikenaka, R. Noguchi, and D.J. Hicklin Vascular endothelial growth factor and receptor interaction is a prerequisite for murine hepatic fibrogenesis Gut 52 2003 1347 1354
-
(2003)
Gut
, vol.52
, pp. 1347-1354
-
-
Yoshiji, H.1
Kuriyama, S.2
Yoshii, J.3
Ikenaka, Y.4
Noguchi, R.5
Hicklin, D.J.6
-
27
-
-
0032500172
-
Coordinated induction of VEGF receptors in mesenchymal cell types during rat hepatic wound healing
-
V. Ankoma-Sey, M. Matli, K.B. Chang, A. Lalazar, D.B. Donner, and L. Wong Coordinated induction of VEGF receptors in mesenchymal cell types during rat hepatic wound healing Oncogene 17 1998 115 121
-
(1998)
Oncogene
, vol.17
, pp. 115-121
-
-
Ankoma-Sey, V.1
Matli, M.2
Chang, K.B.3
Lalazar, A.4
Donner, D.B.5
Wong, L.6
-
28
-
-
0037371341
-
Proangiogenic role of tumor-activated hepatic stellate cells in experimental melanoma metastasis
-
E. Olaso, C. Salado, E. Egilegor, V. Gutierrez, A. Santisteban, and P. Sancho-Bru Proangiogenic role of tumor-activated hepatic stellate cells in experimental melanoma metastasis Hepatology 37 2003 674 685
-
(2003)
Hepatology
, vol.37
, pp. 674-685
-
-
Olaso, E.1
Salado, C.2
Egilegor, E.3
Gutierrez, V.4
Santisteban, A.5
Sancho-Bru, P.6
-
29
-
-
11144332398
-
Hypoxia potentiates transforming growth factor-beta expression of hepatocyte during the cirrhotic condition in rat liver
-
W.I. Jeong, S.H. Do, H.S. Yun, B.J. Song, S.J. Kim, and W.J. Kwak Hypoxia potentiates transforming growth factor-beta expression of hepatocyte during the cirrhotic condition in rat liver Liver Int 24 2004 658 668
-
(2004)
Liver Int
, vol.24
, pp. 658-668
-
-
Jeong, W.I.1
Do, S.H.2
Yun, H.S.3
Song, B.J.4
Kim, S.J.5
Kwak, W.J.6
-
30
-
-
75349086017
-
Hypoxia, angiogenesis and liver fibrogenesis in the progression of chronic liver diseases
-
C. Paternostro, E. David, E. Novo, and M. Parola Hypoxia, angiogenesis and liver fibrogenesis in the progression of chronic liver diseases World J Gastroenterol 16 2010 281 288
-
(2010)
World J Gastroenterol
, vol.16
, pp. 281-288
-
-
Paternostro, C.1
David, E.2
Novo, E.3
Parola, M.4
-
31
-
-
0037371816
-
Oxidants and antioxidants in alcohol-induced liver disease
-
G.E. Arteel Oxidants and antioxidants in alcohol-induced liver disease Gastroenterology 124 2003 778 790
-
(2003)
Gastroenterology
, vol.124
, pp. 778-790
-
-
Arteel, G.E.1
-
32
-
-
75349088284
-
Angiogenesis and liver fibrogenesis
-
L. Valfre di Bonzo, E. Novo, S. Cannito, C. Busletta, C. Paternostro, and D. Povero Angiogenesis and liver fibrogenesis Histol Histopathol 24 2009 1323 1341
-
(2009)
Histol Histopathol
, vol.24
, pp. 1323-1341
-
-
Valfre Di Bonzo, L.1
Novo, E.2
Cannito, S.3
Busletta, C.4
Paternostro, C.5
Povero, D.6
-
33
-
-
48549088729
-
Platelet-derived growth factor signaling through ephrin-b2 regulates hepatic vascular structure and function
-
D. Semela, A. Das, D. Langer, N. Kang, E. Leof, and V. Shah Platelet-derived growth factor signaling through ephrin-b2 regulates hepatic vascular structure and function Gastroenterology 135 2008 671 679
-
(2008)
Gastroenterology
, vol.135
, pp. 671-679
-
-
Semela, D.1
Das, A.2
Langer, D.3
Kang, N.4
Leof, E.5
Shah, V.6
-
34
-
-
0035821645
-
The hepatitis B virus HBx protein induces adherens junction disruption in a src-dependent manner
-
E. Lara-Pezzi, S. Roche, O.M. Andrisani, F. Sanchez-Madrid, and M. Lopez-Cabrera The hepatitis B virus HBx protein induces adherens junction disruption in a src-dependent manner Oncogene 20 2001 3323 3331
-
(2001)
Oncogene
, vol.20
, pp. 3323-3331
-
-
Lara-Pezzi, E.1
Roche, S.2
Andrisani, O.M.3
Sanchez-Madrid, F.4
Lopez-Cabrera, M.5
-
35
-
-
33750607736
-
Leptin-mediated neovascularization is a prerequisite for progression of nonalcoholic steatohepatitis in rats
-
M. Kitade, H. Yoshiji, H. Kojima, Y. Ikenaka, R. Noguchi, and K. Kaji Leptin-mediated neovascularization is a prerequisite for progression of nonalcoholic steatohepatitis in rats Hepatology 44 2006 983 991
-
(2006)
Hepatology
, vol.44
, pp. 983-991
-
-
Kitade, M.1
Yoshiji, H.2
Kojima, H.3
Ikenaka, Y.4
Noguchi, R.5
Kaji, K.6
-
36
-
-
59349121044
-
Angiogenesis in liver disease
-
M. Fernandez, D. Semela, J. Bruix, I. Colle, M. Pinzani, and J. Bosch Angiogenesis in liver disease J Hepatol 50 2009 604 620
-
(2009)
J Hepatol
, vol.50
, pp. 604-620
-
-
Fernandez, M.1
Semela, D.2
Bruix, J.3
Colle, I.4
Pinzani, M.5
Bosch, J.6
-
37
-
-
0032794576
-
Cytokines and fibrogenesis
-
S.L. Friedman Cytokines and fibrogenesis Semin Liver Dis 19 1999 129 140
-
(1999)
Semin Liver Dis
, vol.19
, pp. 129-140
-
-
Friedman, S.L.1
-
38
-
-
13744261157
-
Mac the knife? Macrophagesthe double-edged sword of hepatic fibrosis
-
S.L. Friedman Mac the knife? Macrophagesthe double-edged sword of hepatic fibrosis J Clin Invest 115 2005 29 32
-
(2005)
J Clin Invest
, vol.115
, pp. 29-32
-
-
Friedman, S.L.1
-
40
-
-
33847367730
-
Liver fibrosis: Cellular mechanisms of progression and resolution
-
N.C. Henderson, and J.P. Iredale Liver fibrosis: cellular mechanisms of progression and resolution Clin Sci (Lond) 112 2007 265 280
-
(2007)
Clin Sci (Lond)
, vol.112
, pp. 265-280
-
-
Henderson, N.C.1
Iredale, J.P.2
-
41
-
-
70149090633
-
Liver natural killer and natural killer T cells: Immunobiology and emerging roles in liver diseases
-
B. Gao, S. Radaeva, and O. Park Liver natural killer and natural killer T cells: immunobiology and emerging roles in liver diseases J Leukoc Biol 86 2009 513 528
-
(2009)
J Leukoc Biol
, vol.86
, pp. 513-528
-
-
Gao, B.1
Radaeva, S.2
Park, O.3
-
42
-
-
70449355084
-
In liver fibrosis, dendritic cells govern hepatic inflammation in mice via TNF-alpha
-
M.K. Connolly, A.S. Bedrosian, J. Mallen-St Clair, A.P. Mitchell, J. Ibrahim, and A. Stroud In liver fibrosis, dendritic cells govern hepatic inflammation in mice via TNF-alpha J Clin Invest 119 2009 3213 3225
-
(2009)
J Clin Invest
, vol.119
, pp. 3213-3225
-
-
Connolly, M.K.1
Bedrosian, A.S.2
Mallen-St Clair, J.3
Mitchell, A.P.4
Ibrahim, J.5
Stroud, A.6
-
43
-
-
35948958955
-
TLR4 enhances TGF-beta signaling and hepatic fibrosis
-
E. Seki, S. De Minicis, C.H. Osterreicher, J. Kluwe, Y. Osawa, and D.A. Brenner TLR4 enhances TGF-beta signaling and hepatic fibrosis Nat Med 13 2007 1324 1332
-
(2007)
Nat Med
, vol.13
, pp. 1324-1332
-
-
Seki, E.1
De Minicis, S.2
Osterreicher, C.H.3
Kluwe, J.4
Osawa, Y.5
Brenner, D.A.6
-
44
-
-
66349110620
-
Toll-like receptors as targets in chronic liver diseases
-
A. Mencin, J. Kluwe, and R.F. Schwabe Toll-like receptors as targets in chronic liver diseases Gut 58 2009 704 720
-
(2009)
Gut
, vol.58
, pp. 704-720
-
-
Mencin, A.1
Kluwe, J.2
Schwabe, R.F.3
-
45
-
-
47149105036
-
Toll-like receptors and adaptor molecules in liver disease: Update
-
E. Seki, and D.A. Brenner Toll-like receptors and adaptor molecules in liver disease: update Hepatology 48 2008 322 335
-
(2008)
Hepatology
, vol.48
, pp. 322-335
-
-
Seki, E.1
Brenner, D.A.2
-
46
-
-
0038476330
-
Apoptotic body engulfment by a human stellate cell line is profibrogenic
-
A. Canbay, P. Taimr, N. Torok, H. Higuchi, S. Friedman, and G.J. Gores Apoptotic body engulfment by a human stellate cell line is profibrogenic Lab Invest 83 2003 655 663
-
(2003)
Lab Invest
, vol.83
, pp. 655-663
-
-
Canbay, A.1
Taimr, P.2
Torok, N.3
Higuchi, H.4
Friedman, S.5
Gores, G.J.6
-
47
-
-
0036788277
-
Fas enhances fibrogenesis in the bile duct ligated mouse: A link between apoptosis and fibrosis
-
A. Canbay, H. Higuchi, S.F. Bronk, M. Taniai, T.J. Sebo, and G.J. Gores Fas enhances fibrogenesis in the bile duct ligated mouse: a link between apoptosis and fibrosis Gastroenterology 123 2002 1323 1330
-
(2002)
Gastroenterology
, vol.123
, pp. 1323-1330
-
-
Canbay, A.1
Higuchi, H.2
Bronk, S.F.3
Taniai, M.4
Sebo, T.J.5
Gores, G.J.6
-
48
-
-
33645243410
-
Phagocytosis of apoptotic bodies by hepatic stellate cells induces NADPH oxidase and is associated with liver fibrosis in vivo
-
S.S. Zhan, J.X. Jiang, J. Wu, C. Halsted, S.L. Friedman, and M.A. Zern Phagocytosis of apoptotic bodies by hepatic stellate cells induces NADPH oxidase and is associated with liver fibrosis in vivo Hepatology 43 2006 435 443
-
(2006)
Hepatology
, vol.43
, pp. 435-443
-
-
Zhan, S.S.1
Jiang, J.X.2
Wu, J.3
Halsted, C.4
Friedman, S.L.5
Zern, M.A.6
-
49
-
-
1242336980
-
Apoptosis: The nexus of liver injury and fibrosis
-
A. Canbay, S. Friedman, and G.J. Gores Apoptosis: the nexus of liver injury and fibrosis Hepatology 39 2004 273 278
-
(2004)
Hepatology
, vol.39
, pp. 273-278
-
-
Canbay, A.1
Friedman, S.2
Gores, G.J.3
-
50
-
-
0142151769
-
Kupffer cell engulfment of apoptotic bodies stimulates death ligand and cytokine expression
-
A. Canbay, A.E. Feldstein, H. Higuchi, N. Werneburg, A. Grambihler, and S.F. Bronk Kupffer cell engulfment of apoptotic bodies stimulates death ligand and cytokine expression Hepatology 38 2003 1188 1198
-
(2003)
Hepatology
, vol.38
, pp. 1188-1198
-
-
Canbay, A.1
Feldstein, A.E.2
Higuchi, H.3
Werneburg, N.4
Grambihler, A.5
Bronk, S.F.6
-
51
-
-
33750999322
-
Role of Kupffer cells in host defense and liver disease
-
M. Bilzer, F. Roggel, and A.L. Gerbes Role of Kupffer cells in host defense and liver disease Liver Int 26 2006 1175 1186
-
(2006)
Liver Int
, vol.26
, pp. 1175-1186
-
-
Bilzer, M.1
Roggel, F.2
Gerbes, A.L.3
-
52
-
-
0036548118
-
Inflammation in response to hepatocellular apoptosis
-
H. Jaeschke Inflammation in response to hepatocellular apoptosis Hepatology 35 2002 964 966
-
(2002)
Hepatology
, vol.35
, pp. 964-966
-
-
Jaeschke, H.1
-
53
-
-
0036017174
-
Neutrophil-mediated tissue injury in alcoholic hepatitis
-
H. Jaeschke Neutrophil-mediated tissue injury in alcoholic hepatitis Alcohol 27 2002 23 27
-
(2002)
Alcohol
, vol.27
, pp. 23-27
-
-
Jaeschke, H.1
-
54
-
-
0036226734
-
Role of apoptosis in fibrogenesis
-
M.S. Razzaque, N. Ahsan, and T. Taguchi Role of apoptosis in fibrogenesis Nephron 90 2002 365 372
-
(2002)
Nephron
, vol.90
, pp. 365-372
-
-
Razzaque, M.S.1
Ahsan, N.2
Taguchi, T.3
-
55
-
-
0033107950
-
Life-long caloric restriction suppresses age-associated Fas expression in the Fischer 344 rat kidney
-
M.S. Razzaque, I. Shimokawa, T. Koji, Y. Higami, and T. Taguchi Life-long caloric restriction suppresses age-associated Fas expression in the Fischer 344 rat kidney Mol Cell Biol Res Commun 1 1999 82 85
-
(1999)
Mol Cell Biol Res Commun
, vol.1
, pp. 82-85
-
-
Razzaque, M.S.1
Shimokawa, I.2
Koji, T.3
Higami, Y.4
Taguchi, T.5
-
56
-
-
0031230494
-
Induction of apoptosis and pulmonary fibrosis in mice in response to ligation of Fas antigen
-
N. Hagimoto, K. Kuwano, H. Miyazaki, R. Kunitake, M. Fujita, and M. Kawasaki Induction of apoptosis and pulmonary fibrosis in mice in response to ligation of Fas antigen Am J Respir Cell Mol Biol 17 1997 272 278
-
(1997)
Am J Respir Cell Mol Biol
, vol.17
, pp. 272-278
-
-
Hagimoto, N.1
Kuwano, K.2
Miyazaki, H.3
Kunitake, R.4
Fujita, M.5
Kawasaki, M.6
-
57
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
U. Ozcan, Q. Cao, E. Yilmaz, A.H. Lee, N.N. Iwakoshi, and E. Ozdelen Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes Science 306 2004 457 461
-
(2004)
Science
, vol.306
, pp. 457-461
-
-
Ozcan, U.1
Cao, Q.2
Yilmaz, E.3
Lee, A.H.4
Iwakoshi, N.N.5
Ozdelen, E.6
-
58
-
-
30944451788
-
Saturated fatty acids promote endoplasmic reticulum stress and liver injury in rats with hepatic steatosis
-
D. Wang, Y. Wei, and M.J. Pagliassotti Saturated fatty acids promote endoplasmic reticulum stress and liver injury in rats with hepatic steatosis Endocrinology 147 2006 943 951
-
(2006)
Endocrinology
, vol.147
, pp. 943-951
-
-
Wang, D.1
Wei, Y.2
Pagliassotti, M.J.3
-
59
-
-
21044456174
-
Insulin resistance is a cause of steatosis and fibrosis progression in chronic hepatitis C
-
L. Fartoux, A. Poujol-Robert, J. Guechot, D. Wendum, R. Poupon, and L. Serfaty Insulin resistance is a cause of steatosis and fibrosis progression in chronic hepatitis C Gut 54 2005 1003 1008
-
(2005)
Gut
, vol.54
, pp. 1003-1008
-
-
Fartoux, L.1
Poujol-Robert, A.2
Guechot, J.3
Wendum, D.4
Poupon, R.5
Serfaty, L.6
-
60
-
-
2342559886
-
Steatosis and liver cell apoptosis in chronic hepatitis C: A mechanism for increased liver injury
-
M.J. Walsh, D.M. Vanags, A.D. Clouston, M.M. Richardson, D.M. Purdie, and J.R. Jonsson Steatosis and liver cell apoptosis in chronic hepatitis C: a mechanism for increased liver injury Hepatology 39 2004 1230 1238
-
(2004)
Hepatology
, vol.39
, pp. 1230-1238
-
-
Walsh, M.J.1
Vanags, D.M.2
Clouston, A.D.3
Richardson, M.M.4
Purdie, D.M.5
Jonsson, J.R.6
-
61
-
-
33750606061
-
Long-term follow-up of patients with NAFLD and elevated liver enzymes
-
M. Ekstedt, L.E. Franzen, U.L. Mathiesen, L. Thorelius, M. Holmqvist, and G. Bodemar Long-term follow-up of patients with NAFLD and elevated liver enzymes Hepatology 44 2006 865 873
-
(2006)
Hepatology
, vol.44
, pp. 865-873
-
-
Ekstedt, M.1
Franzen, L.E.2
Mathiesen, U.L.3
Thorelius, L.4
Holmqvist, M.5
Bodemar, G.6
-
63
-
-
0036829092
-
AGA technical review on nonalcoholic fatty liver disease
-
A.J. Sanyal AGA technical review on nonalcoholic fatty liver disease Gastroenterology 123 2002 1705 1725
-
(2002)
Gastroenterology
, vol.123
, pp. 1705-1725
-
-
Sanyal, A.J.1
-
64
-
-
0037382071
-
Dietary habits and their relations to insulin resistance and postprandial lipemia in nonalcoholic steatohepatitis
-
G. Musso, R. Gambino, F. De Michieli, M. Cassader, M. Rizzetto, and M. Durazzo Dietary habits and their relations to insulin resistance and postprandial lipemia in nonalcoholic steatohepatitis Hepatology 37 2003 909 916
-
(2003)
Hepatology
, vol.37
, pp. 909-916
-
-
Musso, G.1
Gambino, R.2
De Michieli, F.3
Cassader, M.4
Rizzetto, M.5
Durazzo, M.6
-
65
-
-
0038643426
-
Inhibition of microsomal triglyceride transfer protein: Another mechanism for drug-induced steatosis in mice
-
P. Letteron, A. Sutton, A. Mansouri, B. Fromenty, and D. Pessayre Inhibition of microsomal triglyceride transfer protein: another mechanism for drug-induced steatosis in mice Hepatology 38 2003 133 140
-
(2003)
Hepatology
, vol.38
, pp. 133-140
-
-
Letteron, P.1
Sutton, A.2
Mansouri, A.3
Fromenty, B.4
Pessayre, D.5
-
66
-
-
34547411540
-
Molecular characterization of the role of orphan receptor small heterodimer partner in development of fatty liver
-
J. Huang, J. Iqbal, P.K. Saha, J. Liu, L. Chan, and M.M. Hussain Molecular characterization of the role of orphan receptor small heterodimer partner in development of fatty liver Hepatology 46 2007 147 157
-
(2007)
Hepatology
, vol.46
, pp. 147-157
-
-
Huang, J.1
Iqbal, J.2
Saha, P.K.3
Liu, J.4
Chan, L.5
Hussain, M.M.6
-
67
-
-
0038643427
-
Central role of PPARalpha-dependent hepatic lipid turnover in dietary steatohepatitis in mice
-
E. Ip, G.C. Farrell, G. Robertson, P. Hall, R. Kirsch, and I. Leclercq Central role of PPARalpha-dependent hepatic lipid turnover in dietary steatohepatitis in mice Hepatology 38 2003 123 132
-
(2003)
Hepatology
, vol.38
, pp. 123-132
-
-
Ip, E.1
Farrell, G.C.2
Robertson, G.3
Hall, P.4
Kirsch, R.5
Leclercq, I.6
-
68
-
-
0041302377
-
The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
-
A. Xu, Y. Wang, H. Keshaw, L.Y. Xu, K.S. Lam, and G.J. Cooper The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice J Clin Invest 112 2003 91 100
-
(2003)
J Clin Invest
, vol.112
, pp. 91-100
-
-
Xu, A.1
Wang, Y.2
Keshaw, H.3
Xu, L.Y.4
Lam, K.S.5
Cooper, G.J.6
-
69
-
-
34547423962
-
Rimonabant reduces obesity-associated hepatic steatosis and features of metabolic syndrome in obese Zucker fa/fa rats
-
M. Gary-Bobo, G. Elachouri, J.F. Gallas, P. Janiak, P. Marini, and C. Ravinet-Trillou Rimonabant reduces obesity-associated hepatic steatosis and features of metabolic syndrome in obese Zucker fa/fa rats Hepatology 46 2007 122 129
-
(2007)
Hepatology
, vol.46
, pp. 122-129
-
-
Gary-Bobo, M.1
Elachouri, G.2
Gallas, J.F.3
Janiak, P.4
Marini, P.5
Ravinet-Trillou, C.6
-
70
-
-
75449101395
-
Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity
-
R. Stienstra, F. Saudale, C. Duval, S. Keshtkar, J.E. Groener, and N. van Rooijen Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity Hepatology 51 2010 511 522
-
(2010)
Hepatology
, vol.51
, pp. 511-522
-
-
Stienstra, R.1
Saudale, F.2
Duval, C.3
Keshtkar, S.4
Groener, J.E.5
Van Rooijen, N.6
-
72
-
-
0025359751
-
Structure of the extracellular matrix in normal and fibrotic liver: Collagens and glycoproteins
-
D. Schuppan Structure of the extracellular matrix in normal and fibrotic liver: collagens and glycoproteins Semin Liver Dis 10 1990 1 10
-
(1990)
Semin Liver Dis
, vol.10
, pp. 1-10
-
-
Schuppan, D.1
-
73
-
-
0033661069
-
Physiological role of sinusoidal endothelial cells and Kupffer cells and their implication in the pathogenesis of liver injury
-
S. Arii, and M. Imamura Physiological role of sinusoidal endothelial cells and Kupffer cells and their implication in the pathogenesis of liver injury J Hepatobiliary Pancreat Surg 7 2000 40 48
-
(2000)
J Hepatobiliary Pancreat Surg
, vol.7
, pp. 40-48
-
-
Arii, S.1
Imamura, M.2
-
74
-
-
0030043492
-
Structure and function of sinusoidal lining cells in the liver
-
E. Wisse, F. Braet, D. Luo, R. De Zanger, D. Jans, and E. Crabbe Structure and function of sinusoidal lining cells in the liver Toxicol Pathol 24 1996 100 111
-
(1996)
Toxicol Pathol
, vol.24
, pp. 100-111
-
-
Wisse, E.1
Braet, F.2
Luo, D.3
De Zanger, R.4
Jans, D.5
Crabbe, E.6
-
75
-
-
0141491358
-
Liver sinusoidal endothelial cells: A new type of organ-resident antigen-presenting cell
-
A. Limmer, and P.A. Knolle Liver sinusoidal endothelial cells: a new type of organ-resident antigen-presenting cell Arch Immunol Ther Exp (Warsz) 49 Suppl. 1 2001 S7 S11
-
(2001)
Arch Immunol Ther Exp (Warsz)
, vol.49
, Issue.SUPPL. 1
-
-
Limmer, A.1
Knolle, P.A.2
-
76
-
-
2942622398
-
Spontaneous recovery from micronodular cirrhosis: Evidence for incomplete resolution associated with matrix cross-linking
-
R. Issa, X. Zhou, C.M. Constandinou, J. Fallowfield, H. Millward-Sadler, and M.D. Gaca Spontaneous recovery from micronodular cirrhosis: evidence for incomplete resolution associated with matrix cross-linking Gastroenterology 126 2004 1795 1808
-
(2004)
Gastroenterology
, vol.126
, pp. 1795-1808
-
-
Issa, R.1
Zhou, X.2
Constandinou, C.M.3
Fallowfield, J.4
Millward-Sadler, H.5
Gaca, M.D.6
-
77
-
-
70349308483
-
Matrix metalloproteinases and their inhibitors as markers of inflammation and fibrosis in chronic liver disease (review)
-
M. Consolo, A. Amoroso, D.A. Spandidos, and M.C. Mazzarino Matrix metalloproteinases and their inhibitors as markers of inflammation and fibrosis in chronic liver disease (review) Int J Mol Med 24 2009 143 152
-
(2009)
Int J Mol Med
, vol.24
, pp. 143-152
-
-
Consolo, M.1
Amoroso, A.2
Spandidos, D.A.3
Mazzarino, M.C.4
-
78
-
-
0030016342
-
The soluble catalytic domain of membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and initiates autoproteolytic activation. Regulation by TIMP-2 and TIMP-3
-
H. Will, S.J. Atkinson, G.S. Butler, B. Smith, and G. Murphy The soluble catalytic domain of membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and initiates autoproteolytic activation. Regulation by TIMP-2 and TIMP-3 J Biol Chem 271 1996 17119 17123
-
(1996)
J Biol Chem
, vol.271
, pp. 17119-17123
-
-
Will, H.1
Atkinson, S.J.2
Butler, G.S.3
Smith, B.4
Murphy, G.5
-
79
-
-
31344458952
-
Structure and function of matrix metalloproteinases and TIMPs
-
H. Nagase, R. Visse, and G. Murphy Structure and function of matrix metalloproteinases and TIMPs Cardiovasc Res 69 2006 562 573
-
(2006)
Cardiovasc Res
, vol.69
, pp. 562-573
-
-
Nagase, H.1
Visse, R.2
Murphy, G.3
-
80
-
-
0034814405
-
Extracellular matrix degradation and the role of hepatic stellate cells
-
R.C. Benyon, and M.J. Arthur Extracellular matrix degradation and the role of hepatic stellate cells Semin Liver Dis 21 2001 373 384
-
(2001)
Semin Liver Dis
, vol.21
, pp. 373-384
-
-
Benyon, R.C.1
Arthur, M.J.2
-
81
-
-
0034809414
-
Hepatic stellate cell behavior during resolution of liver injury
-
J.P. Iredale Hepatic stellate cell behavior during resolution of liver injury Semin Liver Dis 21 2001 427 436
-
(2001)
Semin Liver Dis
, vol.21
, pp. 427-436
-
-
Iredale, J.P.1
-
82
-
-
62949143804
-
Reactive nitrogen species switch on early extracellular matrix remodeling via induction of MMP1 and TNFalpha
-
R. Urtasun, F.J. Cubero, M. Vera, and N. Nieto Reactive nitrogen species switch on early extracellular matrix remodeling via induction of MMP1 and TNFalpha Gastroenterology 136 14101422 2009 e1 e4
-
(2009)
Gastroenterology
, vol.136
, Issue.1410-1422
-
-
Urtasun, R.1
Cubero, F.J.2
Vera, M.3
Nieto, N.4
-
83
-
-
0032835380
-
Matrix metalloproteinase-2 activation in human hepatic fibrosis regulation by cellmatrix interactions
-
A.M. Preaux, A. Mallat, J.T. Nhieu, M.P. D'Ortho, R.M. Hembry, and P. Mavier Matrix metalloproteinase-2 activation in human hepatic fibrosis regulation by cellmatrix interactions Hepatology 30 1999 944 950
-
(1999)
Hepatology
, vol.30
, pp. 944-950
-
-
Preaux, A.M.1
Mallat, A.2
Nhieu, J.T.3
D'Ortho, M.P.4
Hembry, R.M.5
Mavier, P.6
-
84
-
-
0035980914
-
Chronic liver injury, TGF-beta, and cancer
-
D.M. Bissell Chronic liver injury, TGF-beta, and cancer Exp Mol Med 33 2001 179 190
-
(2001)
Exp Mol Med
, vol.33
, pp. 179-190
-
-
Bissell, D.M.1
-
85
-
-
0033646761
-
Tissue inhibitor of metalloproteinases-1 promotes liver fibrosis development in a transgenic mouse model
-
H. Yoshiji, S. Kuriyama, Y. Miyamoto, U.P. Thorgeirsson, D.E. Gomez, and M. Kawata Tissue inhibitor of metalloproteinases-1 promotes liver fibrosis development in a transgenic mouse model Hepatology 32 2000 1248 1254
-
(2000)
Hepatology
, vol.32
, pp. 1248-1254
-
-
Yoshiji, H.1
Kuriyama, S.2
Miyamoto, Y.3
Thorgeirsson, U.P.4
Gomez, D.E.5
Kawata, M.6
-
86
-
-
0037221910
-
Liver fibrosis: Insights into migration of hepatic stellate cells in response to extracellular matrix and growth factors
-
C. Yang, M. Zeisberg, B. Mosterman, A. Sudhakar, U. Yerramalla, and K. Holthaus Liver fibrosis: insights into migration of hepatic stellate cells in response to extracellular matrix and growth factors Gastroenterology 124 2003 147 159
-
(2003)
Gastroenterology
, vol.124
, pp. 147-159
-
-
Yang, C.1
Zeisberg, M.2
Mosterman, B.3
Sudhakar, A.4
Yerramalla, U.5
Holthaus, K.6
-
87
-
-
2642537690
-
Engagement of alphavbeta3 integrin regulates proliferation and apoptosis of hepatic stellate cells
-
X. Zhou, F.R. Murphy, N. Gehdu, J. Zhang, J.P. Iredale, and R.C. Benyon Engagement of alphavbeta3 integrin regulates proliferation and apoptosis of hepatic stellate cells J Biol Chem 279 2004 23996 24006
-
(2004)
J Biol Chem
, vol.279
, pp. 23996-24006
-
-
Zhou, X.1
Murphy, F.R.2
Gehdu, N.3
Zhang, J.4
Iredale, J.P.5
Benyon, R.C.6
-
88
-
-
37149035056
-
Focal adhesion disassembly is an essential early event in hepatic stellate cell chemotaxis
-
A.C. Melton, R.K.J. Soon, J.G. Park, L. Martinez, G.W. Dehart, and H.F.J. Yee Focal adhesion disassembly is an essential early event in hepatic stellate cell chemotaxis Am J Physiol Gastrointest Liver Physiol 293 2007 G1272 G1280
-
(2007)
Am J Physiol Gastrointest Liver Physiol
, vol.293
-
-
Melton, A.C.1
Soon, R.K.J.2
Park, J.G.3
Martinez, L.4
Dehart, G.W.5
Yee, H.F.J.6
-
89
-
-
33747729418
-
The role of integrin-linked kinase in liver wound healing
-
M.S. Shafiei, and D.C. Rockey The role of integrin-linked kinase in liver wound healing J Biol Chem 281 2006 24863 24872
-
(2006)
J Biol Chem
, vol.281
, pp. 24863-24872
-
-
Shafiei, M.S.1
Rockey, D.C.2
-
90
-
-
33748945989
-
Involvement of integrin-linked kinase in carbon tetrachloride-induced hepatic fibrosis in rats
-
Y. Zhang, T. Ikegami, A. Honda, T. Miyazaki, B. Bouscarel, and M. Rojkind Involvement of integrin-linked kinase in carbon tetrachloride-induced hepatic fibrosis in rats Hepatology 44 2006 612 622
-
(2006)
Hepatology
, vol.44
, pp. 612-622
-
-
Zhang, Y.1
Ikegami, T.2
Honda, A.3
Miyazaki, T.4
Bouscarel, B.5
Rojkind, M.6
-
91
-
-
33645533798
-
Galectin-3 regulates myofibroblast activation and hepatic fibrosis
-
N.C. Henderson, A.C. Mackinnon, S.L. Farnworth, F. Poirier, F.P. Russo, and J.P. Iredale Galectin-3 regulates myofibroblast activation and hepatic fibrosis Proc Natl Acad Sci USA 103 2006 5060 5065
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 5060-5065
-
-
Henderson, N.C.1
MacKinnon, A.C.2
Farnworth, S.L.3
Poirier, F.4
Russo, F.P.5
Iredale, J.P.6
-
92
-
-
0037805594
-
Stimulation of proliferation of rat hepatic stellate cells by galectin-1 and galectin-3 through different intracellular signaling pathways
-
N. Maeda, N. Kawada, S. Seki, T. Arakawa, K. Ikeda, and H. Iwao Stimulation of proliferation of rat hepatic stellate cells by galectin-1 and galectin-3 through different intracellular signaling pathways J Biol Chem 278 2003 18938 18944
-
(2003)
J Biol Chem
, vol.278
, pp. 18938-18944
-
-
Maeda, N.1
Kawada, N.2
Seki, S.3
Arakawa, T.4
Ikeda, K.5
Iwao, H.6
-
93
-
-
0035179839
-
DDR2 receptor promotes MMP-2-mediated proliferation and invasion by hepatic stellate cells
-
E. Olaso, K. Ikeda, F.J. Eng, L. Xu, L.H. Wang, and H.C. Lin DDR2 receptor promotes MMP-2-mediated proliferation and invasion by hepatic stellate cells J Clin Invest 108 2001 1369 1378
-
(2001)
J Clin Invest
, vol.108
, pp. 1369-1378
-
-
Olaso, E.1
Ikeda, K.2
Eng, F.J.3
Xu, L.4
Wang, L.H.5
Lin, H.C.6
-
94
-
-
0029913735
-
Expression and function of integrin receptors for collagen and laminin in cultured human hepatic stellate cells
-
V. Carloni, R.G. Romanelli, M. Pinzani, G. Laffi, and P. Gentilini Expression and function of integrin receptors for collagen and laminin in cultured human hepatic stellate cells Gastroenterology 110 1996 1127 1136
-
(1996)
Gastroenterology
, vol.110
, pp. 1127-1136
-
-
Carloni, V.1
Romanelli, R.G.2
Pinzani, M.3
Laffi, G.4
Gentilini, P.5
-
95
-
-
48949084865
-
Connective tissue growth factor: A fibrogenic master switch in fibrotic liver diseases
-
O.A. Gressner, and A.M. Gressner Connective tissue growth factor: a fibrogenic master switch in fibrotic liver diseases Liver Int 28 2008 1065 1079
-
(2008)
Liver Int
, vol.28
, pp. 1065-1079
-
-
Gressner, O.A.1
Gressner, A.M.2
-
96
-
-
35648931933
-
Hepatocyte growth factor promotes remodeling of murine liver fibrosis, accelerating recruitment of bone marrow-derived cells into the liver
-
Y. Asano, Y. Iimuro, G. Son, T. Hirano, and J. Fujimoto Hepatocyte growth factor promotes remodeling of murine liver fibrosis, accelerating recruitment of bone marrow-derived cells into the liver Hepatol Res 37 2007 1080 1094
-
(2007)
Hepatol Res
, vol.37
, pp. 1080-1094
-
-
Asano, Y.1
Iimuro, Y.2
Son, G.3
Hirano, T.4
Fujimoto, J.5
-
97
-
-
0031973105
-
Collagens in the liver extracellular matrix bind hepatocyte growth factor
-
D. Schuppan, M. Schmid, R. Somasundaram, R. Ackermann, M. Ruehl, and T. Nakamura Collagens in the liver extracellular matrix bind hepatocyte growth factor Gastroenterology 114 1998 139 152
-
(1998)
Gastroenterology
, vol.114
, pp. 139-152
-
-
Schuppan, D.1
Schmid, M.2
Somasundaram, R.3
Ackermann, R.4
Ruehl, M.5
Nakamura, T.6
-
98
-
-
54549092104
-
Cellular sources of extracellular matrix in hepatic fibrosis
-
R.G. Wells Cellular sources of extracellular matrix in hepatic fibrosis Clin Liver Dis 12 2008 759 768 viii
-
(2008)
Clin Liver Dis
, vol.12
, pp. 759-768
-
-
Wells, R.G.1
-
99
-
-
34447309766
-
The myofibroblast: One function, multiple origins
-
B. Hinz, S.H. Phan, V.J. Thannickal, A. Galli, M.L. Bochaton-Piallat, and G. Gabbiani The myofibroblast: one function, multiple origins Am J Pathol 170 2007 1807 1816
-
(2007)
Am J Pathol
, vol.170
, pp. 1807-1816
-
-
Hinz, B.1
Phan, S.H.2
Thannickal, V.J.3
Galli, A.4
Bochaton-Piallat, M.L.5
Gabbiani, G.6
-
100
-
-
0023113248
-
Isolation and culture of hepatic lipocytes, Kupffer cells, and sinusoidal endothelial cells by density gradient centrifugation with Stractan
-
S.L. Friedman, and F.J. Roll Isolation and culture of hepatic lipocytes, Kupffer cells, and sinusoidal endothelial cells by density gradient centrifugation with Stractan Anal Biochem 161 1987 207 218
-
(1987)
Anal Biochem
, vol.161
, pp. 207-218
-
-
Friedman, S.L.1
Roll, F.J.2
-
101
-
-
0001520008
-
Hepatic lipocytes: The principal collagen-producing cells of normal rat liver
-
S.L. Friedman, F.J. Roll, J. Boyles, and D.M. Bissell Hepatic lipocytes: the principal collagen-producing cells of normal rat liver Proc Natl Acad Sci USA 82 1985 8681 8685
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 8681-8685
-
-
Friedman, S.L.1
Roll, F.J.2
Boyles, J.3
Bissell, D.M.4
-
102
-
-
0025000652
-
Extracellular matrix gene expression increases preferentially in rat lipocytes and sinusoidal endothelial cells during hepatic fibrosis in vivo
-
J.J. Maher, and R.F. McGuire Extracellular matrix gene expression increases preferentially in rat lipocytes and sinusoidal endothelial cells during hepatic fibrosis in vivo J Clin Invest 86 1990 1641 1648
-
(1990)
J Clin Invest
, vol.86
, pp. 1641-1648
-
-
Maher, J.J.1
McGuire, R.F.2
-
103
-
-
0025301290
-
Cellular distribution of transforming growth factor-beta 1 and procollagen types I, III, and IV transcripts in carbon tetrachloride-induced rat liver fibrosis
-
H. Nakatsukasa, P. Nagy, R.P. Evarts, C.C. Hsia, E. Marsden, and S.S. Thorgeirsson Cellular distribution of transforming growth factor-beta 1 and procollagen types I, III, and IV transcripts in carbon tetrachloride-induced rat liver fibrosis J Clin Invest 85 1990 1833 1843
-
(1990)
J Clin Invest
, vol.85
, pp. 1833-1843
-
-
Nakatsukasa, H.1
Nagy, P.2
Evarts, R.P.3
Hsia, C.C.4
Marsden, E.5
Thorgeirsson, S.S.6
-
105
-
-
0022413232
-
Perisinusoidal fat-storing cells are the main vitamin A storage sites in rat liver
-
H.F. Hendriks, W.A. Verhoofstad, A. Brouwer, A.M. de Leeuw, and D.L. Knook Perisinusoidal fat-storing cells are the main vitamin A storage sites in rat liver Exp Cell Res 160 1985 138 149
-
(1985)
Exp Cell Res
, vol.160
, pp. 138-149
-
-
Hendriks, H.F.1
Verhoofstad, W.A.2
Brouwer, A.3
De Leeuw, A.M.4
Knook, D.L.5
-
106
-
-
0030998255
-
Induction of neutrophil-attracting chemokines in transforming rat hepatic stellate cells
-
H. Sprenger, A. Kaufmann, H. Garn, B. Lahme, D. Gemsa, and A.M. Gressner Induction of neutrophil-attracting chemokines in transforming rat hepatic stellate cells Gastroenterology 113 1997 277 285
-
(1997)
Gastroenterology
, vol.113
, pp. 277-285
-
-
Sprenger, H.1
Kaufmann, A.2
Garn, H.3
Lahme, B.4
Gemsa, D.5
Gressner, A.M.6
-
107
-
-
0027360267
-
Cultured human liver fat-storing cells produce monocyte chemotactic protein-1. Regulation by proinflammatory cytokines
-
F. Marra, A.J. Valente, M. Pinzani, and H.E. Abboud Cultured human liver fat-storing cells produce monocyte chemotactic protein-1. Regulation by proinflammatory cytokines J Clin Invest 92 1993 1674 1680
-
(1993)
J Clin Invest
, vol.92
, pp. 1674-1680
-
-
Marra, F.1
Valente, A.J.2
Pinzani, M.3
Abboud, H.E.4
-
108
-
-
0036051963
-
Role of hepatic stellate cells in the pathogenesis of portal hypertension
-
F. Marra, and M. Pinzani Role of hepatic stellate cells in the pathogenesis of portal hypertension Nefrologia 22 Suppl. 5 2002 34 40
-
(2002)
Nefrologia
, vol.22
, Issue.SUPPL. 5
, pp. 34-40
-
-
Marra, F.1
Pinzani, M.2
-
109
-
-
0038185316
-
Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells
-
Y.H. Paik, R.F. Schwabe, R. Bataller, M.P. Russo, C. Jobin, and D.A. Brenner Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells Hepatology 37 2003 1043 1055
-
(2003)
Hepatology
, vol.37
, pp. 1043-1055
-
-
Paik, Y.H.1
Schwabe, R.F.2
Bataller, R.3
Russo, M.P.4
Jobin, C.5
Brenner, D.A.6
-
110
-
-
33745129374
-
Hepatic stellate cells primed with cytokines upregulate inflammation in response to peptidoglycan or lipoteichoic acid
-
Y.H. Paik, K.S. Lee, H.J. Lee, K.M. Yang, S.J. Lee, and D.K. Lee Hepatic stellate cells primed with cytokines upregulate inflammation in response to peptidoglycan or lipoteichoic acid Lab Invest 86 2006 676 686
-
(2006)
Lab Invest
, vol.86
, pp. 676-686
-
-
Paik, Y.H.1
Lee, K.S.2
Lee, H.J.3
Yang, K.M.4
Lee, S.J.5
Lee, D.K.6
-
111
-
-
24044432235
-
Exposure to bacterial cell wall products triggers an inflammatory phenotype in hepatic stellate cells
-
P. Brun, I. Castagliuolo, M. Pinzani, G. Palu, and D. Martines Exposure to bacterial cell wall products triggers an inflammatory phenotype in hepatic stellate cells Am J Physiol Gastrointest Liver Physiol 289 2005 G571 G578
-
(2005)
Am J Physiol Gastrointest Liver Physiol
, vol.289
-
-
Brun, P.1
Castagliuolo, I.2
Pinzani, M.3
Palu, G.4
Martines, D.5
-
112
-
-
33846212347
-
Ito cells are liver-resident antigen-presenting cells for activating T cell responses
-
F. Winau, G. Hegasy, R. Weiskirchen, S. Weber, C. Cassan, and P.A. Sieling Ito cells are liver-resident antigen-presenting cells for activating T cell responses Immunity 26 2007 117 129
-
(2007)
Immunity
, vol.26
, pp. 117-129
-
-
Winau, F.1
Hegasy, G.2
Weiskirchen, R.3
Weber, S.4
Cassan, C.5
Sieling, P.A.6
-
113
-
-
4444289142
-
Immune stimulation of hepatic fibrogenesis by CD8 cells and attenuation by transgenic interleukin-10 from hepatocytes
-
R. Safadi, M. Ohta, C.E. Alvarez, M.I. Fiel, M. Bansal, and W.Z. Mehal Immune stimulation of hepatic fibrogenesis by CD8 cells and attenuation by transgenic interleukin-10 from hepatocytes Gastroenterology 127 2004 870 882
-
(2004)
Gastroenterology
, vol.127
, pp. 870-882
-
-
Safadi, R.1
Ohta, M.2
Alvarez, C.E.3
Fiel, M.I.4
Bansal, M.5
Mehal, W.Z.6
-
114
-
-
0026085410
-
Apolipoprotein e is secreted by cultured lipocytes of the rat liver
-
G. Friedman, L.M. Liu, S.L. Friedman, and J.K. Boyles Apolipoprotein E is secreted by cultured lipocytes of the rat liver J Lipid Res 32 1991 107 114
-
(1991)
J Lipid Res
, vol.32
, pp. 107-114
-
-
Friedman, G.1
Liu, L.M.2
Friedman, S.L.3
Boyles, J.K.4
-
115
-
-
0025719622
-
Dexamethasone modulates alpha 2-macroglobulin and apolipoprotein e gene expression in cultured rat liver fat-storing (Ito) cells
-
G. Ramadori, T. Knittel, S. Schwogler, F. Bieber, H. Rieder, and K.H. Meyer zum Buschenfelde Dexamethasone modulates alpha 2-macroglobulin and apolipoprotein E gene expression in cultured rat liver fat-storing (Ito) cells Hepatology 14 1991 875 882
-
(1991)
Hepatology
, vol.14
, pp. 875-882
-
-
Ramadori, G.1
Knittel, T.2
Schwogler, S.3
Bieber, F.4
Rieder, H.5
Meyer Zum Buschenfelde, K.H.6
-
116
-
-
34147117966
-
Regulation of hepatic stellate cell differentiation by the neurotrophin receptor p75NTR
-
M.A. Passino, R.A. Adams, S.L. Sikorski, and K. Akassoglou Regulation of hepatic stellate cell differentiation by the neurotrophin receptor p75NTR Science 315 2007 1853 1856
-
(2007)
Science
, vol.315
, pp. 1853-1856
-
-
Passino, M.A.1
Adams, R.A.2
Sikorski, S.L.3
Akassoglou, K.4
-
117
-
-
0027264871
-
Cell-specific expression of hepatocyte growth factor in liver. Upregulation in sinusoidal endothelial cells after carbon tetrachloride
-
J.J. Maher Cell-specific expression of hepatocyte growth factor in liver. Upregulation in sinusoidal endothelial cells after carbon tetrachloride J Clin Invest 91 1993 2244 2252
-
(1993)
J Clin Invest
, vol.91
, pp. 2244-2252
-
-
Maher, J.J.1
-
118
-
-
0034723290
-
Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury
-
S.L. Friedman Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury J Biol Chem 275 2000 2247 2250
-
(2000)
J Biol Chem
, vol.275
, pp. 2247-2250
-
-
Friedman, S.L.1
-
121
-
-
22344452756
-
Hepatitis C virus-replicating hepatocytes induce fibrogenic activation of hepatic stellate cells
-
A. Schulze-Krebs, D. Preimel, Y. Popov, R. Bartenschlager, V. Lohmann, and M. Pinzani Hepatitis C virus-replicating hepatocytes induce fibrogenic activation of hepatic stellate cells Gastroenterology 129 2005 246 258
-
(2005)
Gastroenterology
, vol.129
, pp. 246-258
-
-
Schulze-Krebs, A.1
Preimel, D.2
Popov, Y.3
Bartenschlager, R.4
Lohmann, V.5
Pinzani, M.6
-
122
-
-
56349107309
-
Hepatic fibrosisoverview
-
S.L. Friedman Hepatic fibrosisoverview Toxicology 254 2008 120 129
-
(2008)
Toxicology
, vol.254
, pp. 120-129
-
-
Friedman, S.L.1
-
123
-
-
0028596335
-
Expression of variant fibronectins in wound healing: Cellular source and biological activity of the EIIIA segment in rat hepatic fibrogenesis
-
W.R. Jarnagin, D.C. Rockey, V.E. Koteliansky, S.S. Wang, and D.M. Bissell Expression of variant fibronectins in wound healing: cellular source and biological activity of the EIIIA segment in rat hepatic fibrogenesis J Cell Biol 127 1994 2037 2048
-
(1994)
J Cell Biol
, vol.127
, pp. 2037-2048
-
-
Jarnagin, W.R.1
Rockey, D.C.2
Koteliansky, V.E.3
Wang, S.S.4
Bissell, D.M.5
-
124
-
-
84945733905
-
The role of thrombocytes in liver fibrogenesis: Effects of platelet lysate and thrombocyte-derived growth factors on the mitogenic activity and glycosaminoglycan synthesis of cultured rat liver fat storing cells
-
M.G. Bachem, R. Melchior, and A.M. Gressner The role of thrombocytes in liver fibrogenesis: effects of platelet lysate and thrombocyte-derived growth factors on the mitogenic activity and glycosaminoglycan synthesis of cultured rat liver fat storing cells J Clin Chem Clin Biochem 27 1989 555 565
-
(1989)
J Clin Chem Clin Biochem
, vol.27
, pp. 555-565
-
-
Bachem, M.G.1
Melchior, R.2
Gressner, A.M.3
-
125
-
-
4243344912
-
PDGF and signal transduction in hepatic stellate cells
-
M. Pinzani PDGF and signal transduction in hepatic stellate cells Front Biosci 7 2002 d1720 d1726
-
(2002)
Front Biosci
, vol.7
-
-
Pinzani, M.1
-
126
-
-
34247619289
-
Pro-fibrogenic potential of PDGF-D in liver fibrosis
-
E. Borkham-Kamphorst, C.R. van Roeyen, T. Ostendorf, J. Floege, A.M. Gressner, and R. Weiskirchen Pro-fibrogenic potential of PDGF-D in liver fibrosis J Hepatol 46 2007 1064 1074
-
(2007)
J Hepatol
, vol.46
, pp. 1064-1074
-
-
Borkham-Kamphorst, E.1
Van Roeyen, C.R.2
Ostendorf, T.3
Floege, J.4
Gressner, A.M.5
Weiskirchen, R.6
-
127
-
-
0034810089
-
Cytokine receptors and signaling in hepatic stellate cells
-
M. Pinzani, and F. Marra Cytokine receptors and signaling in hepatic stellate cells Semin Liver Dis 21 2001 397 416
-
(2001)
Semin Liver Dis
, vol.21
, pp. 397-416
-
-
Pinzani, M.1
Marra, F.2
-
128
-
-
33845411186
-
PI3K is involved in PDGF-beta receptor upregulation post-PDGF-BB treatment in mouse HSC
-
C.G. Lechuga, Z.H. Hernandez-Nazara, E. Hernandez, M. Bustamante, G. Desierto, and A. Cotty PI3K is involved in PDGF-beta receptor upregulation post-PDGF-BB treatment in mouse HSC Am J Physiol Gastrointest Liver Physiol 291 2006 G1051 G1061
-
(2006)
Am J Physiol Gastrointest Liver Physiol
, vol.291
-
-
Lechuga, C.G.1
Hernandez-Nazara, Z.H.2
Hernandez, E.3
Bustamante, M.4
Desierto, G.5
Cotty, A.6
-
129
-
-
0034804406
-
Hepatic blood flow regulation by stellate cells in normal and injured liver
-
D.C. Rockey Hepatic blood flow regulation by stellate cells in normal and injured liver Semin Liver Dis 21 2001 337 349
-
(2001)
Semin Liver Dis
, vol.21
, pp. 337-349
-
-
Rockey, D.C.1
-
130
-
-
0034856044
-
Cellular pathophysiology of portal hypertension and prospects for management with gene therapy
-
D.C. Rockey Cellular pathophysiology of portal hypertension and prospects for management with gene therapy Clin Liver Dis 5 2001 851 865
-
(2001)
Clin Liver Dis
, vol.5
, pp. 851-865
-
-
Rockey, D.C.1
-
131
-
-
0037222762
-
Vascular mediators in the injured liver
-
D.C. Rockey Vascular mediators in the injured liver Hepatology 37 2003 4 12
-
(2003)
Hepatology
, vol.37
, pp. 4-12
-
-
Rockey, D.C.1
-
132
-
-
0036284634
-
Hepatic stellate cells: Role in microcirculation and pathophysiology of portal hypertension
-
H. Reynaert, M.G. Thompson, T. Thomas, and A. Geerts Hepatic stellate cells: role in microcirculation and pathophysiology of portal hypertension Gut 50 2002 571 581
-
(2002)
Gut
, vol.50
, pp. 571-581
-
-
Reynaert, H.1
Thompson, M.G.2
Thomas, T.3
Geerts, A.4
-
133
-
-
0026775513
-
Fat-storing cells as liver-specific pericytes. Spatial dynamics of agonist-stimulated intracellular calcium transients
-
M. Pinzani, P. Failli, C. Ruocco, A. Casini, S. Milani, and E. Baldi Fat-storing cells as liver-specific pericytes. Spatial dynamics of agonist-stimulated intracellular calcium transients J Clin Invest 90 1992 642 646
-
(1992)
J Clin Invest
, vol.90
, pp. 642-646
-
-
Pinzani, M.1
Failli, P.2
Ruocco, C.3
Casini, A.4
Milani, S.5
Baldi, E.6
-
134
-
-
33644807897
-
[Ca2+]i-independent contractile force generation by rat hepatic stellate cells in response to endothelin-1
-
A.C. Melton, A. Datta, and H.F.J. Yee [Ca2+]i-independent contractile force generation by rat hepatic stellate cells in response to endothelin-1 Am J Physiol Gastrointest Liver Physiol 290 2006 G7 13
-
(2006)
Am J Physiol Gastrointest Liver Physiol
, vol.290
, pp. 7-13
-
-
Melton, A.C.1
Datta, A.2
Yee, H.F.J.3
-
135
-
-
54549111222
-
Stellate cell contraction: Role, regulation, and potential therapeutic target
-
R.K.J. Soon, and H.F.J. Yee Stellate cell contraction: role, regulation, and potential therapeutic target Clin Liver Dis 12 2008 791 803 viii
-
(2008)
Clin Liver Dis
, vol.12
, pp. 791-803
-
-
Soon, R.K.J.1
Yee, H.F.J.2
-
136
-
-
0033053458
-
Transforming growth factor beta1 induces the expression of alpha1(I) procollagen mRNA by a hydrogen peroxide-C/EBPbeta-dependent mechanism in rat hepatic stellate cells
-
E.R. Garcia-Trevijano, M.J. Iraburu, L. Fontana, J.A. Dominguez-Rosales, A. Auster, and A. Covarrubias-Pinedo Transforming growth factor beta1 induces the expression of alpha1(I) procollagen mRNA by a hydrogen peroxide-C/EBPbeta- dependent mechanism in rat hepatic stellate cells Hepatology 29 1999 960 970
-
(1999)
Hepatology
, vol.29
, pp. 960-970
-
-
Garcia-Trevijano, E.R.1
Iraburu, M.J.2
Fontana, L.3
Dominguez-Rosales, J.A.4
Auster, A.5
Covarrubias-Pinedo, A.6
-
137
-
-
0029024766
-
Collagenases and liver fibrosis
-
M.J. Arthur Collagenases and liver fibrosis J Hepatol 22 1995 43 48
-
(1995)
J Hepatol
, vol.22
, pp. 43-48
-
-
Arthur, M.J.1
-
138
-
-
0032934278
-
Monocyte chemotactic protein-1 as a chemoattractant for human hepatic stellate cells
-
F. Marra, R.G. Romanelli, C. Giannini, P. Failli, S. Pastacaldi, and M.C. Arrighi Monocyte chemotactic protein-1 as a chemoattractant for human hepatic stellate cells Hepatology 29 1999 140 148
-
(1999)
Hepatology
, vol.29
, pp. 140-148
-
-
Marra, F.1
Romanelli, R.G.2
Giannini, C.3
Failli, P.4
Pastacaldi, S.5
Arrighi, M.C.6
-
139
-
-
0035971215
-
Signal transduction by the chemokine receptor CXCR3: Activation of Ras/ERK, Src, and phosphatidylinositol 3-kinase/Akt controls cell migration and proliferation in human vascular pericytes
-
A. Bonacchi, P. Romagnani, R.G. Romanelli, E. Efsen, F. Annunziato, and L. Lasagni Signal transduction by the chemokine receptor CXCR3: activation of Ras/ERK, Src, and phosphatidylinositol 3-kinase/Akt controls cell migration and proliferation in human vascular pericytes J Biol Chem 276 2001 9945 9954
-
(2001)
J Biol Chem
, vol.276
, pp. 9945-9954
-
-
Bonacchi, A.1
Romagnani, P.2
Romanelli, R.G.3
Efsen, E.4
Annunziato, F.5
Lasagni, L.6
-
140
-
-
0033061550
-
In vitro migratory potential of rat quiescent hepatic stellate cells and its augmentation by cell activation
-
K. Ikeda, T. Wakahara, Y.Q. Wang, H. Kadoya, N. Kawada, and K. Kaneda In vitro migratory potential of rat quiescent hepatic stellate cells and its augmentation by cell activation Hepatology 29 1999 1760 1767
-
(1999)
Hepatology
, vol.29
, pp. 1760-1767
-
-
Ikeda, K.1
Wakahara, T.2
Wang, Y.Q.3
Kadoya, H.4
Kawada, N.5
Kaneda, K.6
-
141
-
-
0034086195
-
PDGF-mediated chemoattraction of hepatic stellate cells by bile duct segments in cholestatic liver injury
-
N. Kinnman, R. Hultcrantz, V. Barbu, C. Rey, D. Wendum, and R. Poupon PDGF-mediated chemoattraction of hepatic stellate cells by bile duct segments in cholestatic liver injury Lab Invest 80 2000 697 707
-
(2000)
Lab Invest
, vol.80
, pp. 697-707
-
-
Kinnman, N.1
Hultcrantz, R.2
Barbu, V.3
Rey, C.4
Wendum, D.5
Poupon, R.6
-
142
-
-
0042092032
-
Connective tissue growth factor (CTGF/CCN2) in hepatic fibrosis
-
A.W. Rachfal, and D.R. Brigstock Connective tissue growth factor (CTGF/CCN2) in hepatic fibrosis Hepatol Res 26 2003 1 9
-
(2003)
Hepatol Res
, vol.26
, pp. 1-9
-
-
Rachfal, A.W.1
Brigstock, D.R.2
-
143
-
-
1542305557
-
Connective tissue growth factor (CCN2) induces adhesion of rat activated hepatic stellate cells by binding of its C-terminal domain to integrin alpha(v)beta(3) and heparan sulfate proteoglycan
-
R. Gao, and D.R. Brigstock Connective tissue growth factor (CCN2) induces adhesion of rat activated hepatic stellate cells by binding of its C-terminal domain to integrin alpha(v)beta(3) and heparan sulfate proteoglycan J Biol Chem 279 2004 8848 8855
-
(2004)
J Biol Chem
, vol.279
, pp. 8848-8855
-
-
Gao, R.1
Brigstock, D.R.2
-
144
-
-
33751539470
-
CD133+ hepatic stellate cells are progenitor cells
-
C. Kordes, I. Sawitza, A. Muller-Marbach, N. Ale-Agha, V. Keitel, and H. Klonowski-Stumpe CD133+ hepatic stellate cells are progenitor cells Biochem Biophys Res Commun 352 2007 410 417
-
(2007)
Biochem Biophys Res Commun
, vol.352
, pp. 410-417
-
-
Kordes, C.1
Sawitza, I.2
Muller-Marbach, A.3
Ale-Agha, N.4
Keitel, V.5
Klonowski-Stumpe, H.6
-
146
-
-
0036241046
-
The pathobiology of biliary epithelia
-
G. Alpini, J.M. McGill, and N.F. Larusso The pathobiology of biliary epithelia Hepatology 35 2002 1256 1268
-
(2002)
Hepatology
, vol.35
, pp. 1256-1268
-
-
Alpini, G.1
McGill, J.M.2
Larusso, N.F.3
-
147
-
-
0032742051
-
Rat liver myofibroblasts and hepatic stellate cells: Different cell populations of the fibroblast lineage with fibrogenic potential
-
T. Knittel, D. Kobold, B. Saile, A. Grundmann, K. Neubauer, and F. Piscaglia Rat liver myofibroblasts and hepatic stellate cells: different cell populations of the fibroblast lineage with fibrogenic potential Gastroenterology 117 1999 1205 1221
-
(1999)
Gastroenterology
, vol.117
, pp. 1205-1221
-
-
Knittel, T.1
Kobold, D.2
Saile, B.3
Grundmann, A.4
Neubauer, K.5
Piscaglia, F.6
-
148
-
-
33847636334
-
Prominent contribution of portal mesenchymal cells to liver fibrosis in ischemic and obstructive cholestatic injuries
-
M. Beaussier, D. Wendum, E. Schiffer, S. Dumont, C. Rey, and A. Lienhart Prominent contribution of portal mesenchymal cells to liver fibrosis in ischemic and obstructive cholestatic injuries Lab Invest 87 2007 292 303
-
(2007)
Lab Invest
, vol.87
, pp. 292-303
-
-
Beaussier, M.1
Wendum, D.2
Schiffer, E.3
Dumont, S.4
Rey, C.5
Lienhart, A.6
-
149
-
-
0030032905
-
Proliferation and phenotypic modulation of portal fibroblasts in the early stages of cholestatic fibrosis in the rat
-
B. Tuchweber, A. Desmouliere, M.L. Bochaton-Piallat, L. Rubbia-Brandt, and G. Gabbiani Proliferation and phenotypic modulation of portal fibroblasts in the early stages of cholestatic fibrosis in the rat Lab Invest 74 1996 265 278
-
(1996)
Lab Invest
, vol.74
, pp. 265-278
-
-
Tuchweber, B.1
Desmouliere, A.2
Bochaton-Piallat, M.L.3
Rubbia-Brandt, L.4
Gabbiani, G.5
-
150
-
-
0027958521
-
Ito cell heterogeneity: Desmin-negative Ito cells in normal rat liver
-
G. Ballardini, P. Groff, L. Badiali de Giorgi, D. Schuppan, and F.B. Bianchi Ito cell heterogeneity: desmin-negative Ito cells in normal rat liver Hepatology 19 1994 440 446
-
(1994)
Hepatology
, vol.19
, pp. 440-446
-
-
Ballardini, G.1
Groff, P.2
Badiali De Giorgi, L.3
Schuppan, D.4
Bianchi, F.B.5
-
151
-
-
0036828987
-
The ecto-nucleoside triphosphate diphosphohydrolase NTPDase2/CD39L1 is expressed in a novel functional compartment within the liver
-
J.A. Dranoff, E.A. Kruglov, S.C. Robson, N. Braun, H. Zimmermann, and J. Sevigny The ecto-nucleoside triphosphate diphosphohydrolase NTPDase2/CD39L1 is expressed in a novel functional compartment within the liver Hepatology 36 2002 1135 1144
-
(2002)
Hepatology
, vol.36
, pp. 1135-1144
-
-
Dranoff, J.A.1
Kruglov, E.A.2
Robson, S.C.3
Braun, N.4
Zimmermann, H.5
Sevigny, J.6
-
152
-
-
77950611682
-
Portal fibroblasts: Underappreciated mediators of biliary fibrosis
-
J.A. Dranoff, and R.G. Wells Portal fibroblasts: underappreciated mediators of biliary fibrosis Hepatology 51 2010 1438 1444
-
(2010)
Hepatology
, vol.51
, pp. 1438-1444
-
-
Dranoff, J.A.1
Wells, R.G.2
-
153
-
-
0036166579
-
Hepatic stellate cell/myofibroblast subpopulations in fibrotic human and rat livers
-
D. Cassiman, L. Libbrecht, V. Desmet, C. Denef, and T. Roskams Hepatic stellate cell/myofibroblast subpopulations in fibrotic human and rat livers J Hepatol 36 2002 200 209
-
(2002)
J Hepatol
, vol.36
, pp. 200-209
-
-
Cassiman, D.1
Libbrecht, L.2
Desmet, V.3
Denef, C.4
Roskams, T.5
-
154
-
-
1542504567
-
Portal tract fibrogenesis in the liver
-
G. Ramadori, and B. Saile Portal tract fibrogenesis in the liver Lab Invest 84 2004 153 159
-
(2004)
Lab Invest
, vol.84
, pp. 153-159
-
-
Ramadori, G.1
Saile, B.2
-
155
-
-
77649168237
-
Distinct proteomic features of two fibrogenic liver cell populations: Hepatic stellate cells and portal myofibroblasts
-
N. Bosselut, C. Housset, P. Marcelo, C. Rey, T. Burmester, and J. Vinh Distinct proteomic features of two fibrogenic liver cell populations: hepatic stellate cells and portal myofibroblasts Proteomics 10 2010 1017 1028
-
(2010)
Proteomics
, vol.10
, pp. 1017-1028
-
-
Bosselut, N.1
Housset, C.2
Marcelo, P.3
Rey, C.4
Burmester, T.5
Vinh, J.6
-
156
-
-
0442323488
-
Autocrine release of TGF-beta by portal fibroblasts regulates cell growth
-
R.G. Wells, E. Kruglov, and J.A. Dranoff Autocrine release of TGF-beta by portal fibroblasts regulates cell growth FEBS Lett 559 2004 107 110
-
(2004)
FEBS Lett
, vol.559
, pp. 107-110
-
-
Wells, R.G.1
Kruglov, E.2
Dranoff, J.A.3
-
157
-
-
20744441669
-
Portal fibroblasts regulate the proliferation of bile duct epithelia via expression of NTPDase2
-
M.N. Jhandier, E.A. Kruglov, E.G. Lavoie, J. Sevigny, and J.A. Dranoff Portal fibroblasts regulate the proliferation of bile duct epithelia via expression of NTPDase2 J Biol Chem 280 2005 22986 22992
-
(2005)
J Biol Chem
, vol.280
, pp. 22986-22992
-
-
Jhandier, M.N.1
Kruglov, E.A.2
Lavoie, E.G.3
Sevigny, J.4
Dranoff, J.A.5
-
158
-
-
0037329896
-
The myofibroblastic conversion of peribiliary fibrogenic cells distinct from hepatic stellate cells is stimulated by platelet-derived growth factor during liver fibrogenesis
-
N. Kinnman, C. Francoz, V. Barbu, D. Wendum, C. Rey, and R. Hultcrantz The myofibroblastic conversion of peribiliary fibrogenic cells distinct from hepatic stellate cells is stimulated by platelet-derived growth factor during liver fibrogenesis Lab Invest 83 2003 163 173
-
(2003)
Lab Invest
, vol.83
, pp. 163-173
-
-
Kinnman, N.1
Francoz, C.2
Barbu, V.3
Wendum, D.4
Rey, C.5
Hultcrantz, R.6
-
159
-
-
1642450657
-
Commitment of bone marrow cells to hepatic stellate cells in mouse
-
S. Baba, H. Fujii, T. Hirose, K. Yasuchika, H. Azuma, and T. Hoppo Commitment of bone marrow cells to hepatic stellate cells in mouse J Hepatol 40 2004 255 260
-
(2004)
J Hepatol
, vol.40
, pp. 255-260
-
-
Baba, S.1
Fujii, H.2
Hirose, T.3
Yasuchika, K.4
Azuma, H.5
Hoppo, T.6
-
160
-
-
38549127166
-
Human mesenchymal stem cells as a two-edged sword in hepatic regenerative medicine: Engraftment and hepatocyte differentiation versus profibrogenic potential
-
L.V. di Bonzo, I. Ferrero, C. Cravanzola, K. Mareschi, D. Rustichell, and E. Novo Human mesenchymal stem cells as a two-edged sword in hepatic regenerative medicine: engraftment and hepatocyte differentiation versus profibrogenic potential Gut 57 2008 223 231
-
(2008)
Gut
, vol.57
, pp. 223-231
-
-
Di Bonzo, L.V.1
Ferrero, I.2
Cravanzola, C.3
Mareschi, K.4
Rustichell, D.5
Novo, E.6
-
161
-
-
67349239849
-
Homing of bone marrow mesenchymal stem cells mediated by sphingosine 1-phosphate contributes to liver fibrosis
-
C. Li, Y. Kong, H. Wang, S. Wang, H. Yu, and X. Liu Homing of bone marrow mesenchymal stem cells mediated by sphingosine 1-phosphate contributes to liver fibrosis J Hepatol 50 2009 1174 1183
-
(2009)
J Hepatol
, vol.50
, pp. 1174-1183
-
-
Li, C.1
Kong, Y.2
Wang, H.3
Wang, S.4
Yu, H.5
Liu, X.6
-
162
-
-
1842531265
-
A significant proportion of myofibroblasts are of bone marrow origin in human liver fibrosis
-
S.J. Forbes, F.P. Russo, V. Rey, P. Burra, M. Rugge, and N.A. Wright A significant proportion of myofibroblasts are of bone marrow origin in human liver fibrosis Gastroenterology 126 2004 955 963
-
(2004)
Gastroenterology
, vol.126
, pp. 955-963
-
-
Forbes, S.J.1
Russo, F.P.2
Rey, V.3
Burra, P.4
Rugge, M.5
Wright, N.A.6
-
163
-
-
33646372957
-
The bone marrow functionally contributes to liver fibrosis
-
F.P. Russo, M.R. Alison, B.W. Bigger, E. Amofah, A. Florou, and F. Amin The bone marrow functionally contributes to liver fibrosis Gastroenterology 130 2006 1807 1821
-
(2006)
Gastroenterology
, vol.130
, pp. 1807-1821
-
-
Russo, F.P.1
Alison, M.R.2
Bigger, B.W.3
Amofah, E.4
Florou, A.5
Amin, F.6
-
164
-
-
33746494050
-
Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis
-
T. Kisseleva, H. Uchinami, N. Feirt, O. Quintana-Bustamante, J.C. Segovia, and R.F. Schwabe Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis J Hepatol 45 2006 429 438
-
(2006)
J Hepatol
, vol.45
, pp. 429-438
-
-
Kisseleva, T.1
Uchinami, H.2
Feirt, N.3
Quintana-Bustamante, O.4
Segovia, J.C.5
Schwabe, R.F.6
-
165
-
-
41349108024
-
Hematopoietic origin of hepatic stellate cells in the adult liver
-
E. Miyata, M. Masuya, S. Yoshida, S. Nakamura, K. Kato, and Y. Sugimoto Hematopoietic origin of hepatic stellate cells in the adult liver Blood 111 2008 2427 2435
-
(2008)
Blood
, vol.111
, pp. 2427-2435
-
-
Miyata, E.1
Masuya, M.2
Yoshida, S.3
Nakamura, S.4
Kato, K.5
Sugimoto, Y.6
-
166
-
-
69749092999
-
Pathological roles of bone marrow-derived stellate cells in a mouse model of alcohol-induced fatty liver
-
T. Fujimiya, J. Liu, H. Kojima, S. Shirafuji, H. Kimura, and M. Fujimiya Pathological roles of bone marrow-derived stellate cells in a mouse model of alcohol-induced fatty liver Am J Physiol Gastrointest Liver Physiol 297 2009 G451 G460
-
(2009)
Am J Physiol Gastrointest Liver Physiol
, vol.297
-
-
Fujimiya, T.1
Liu, J.2
Kojima, H.3
Shirafuji, S.4
Kimura, H.5
Fujimiya, M.6
-
167
-
-
34948902752
-
Participation of bone marrow cells in biliary fibrosis after bile duct ligation
-
S. Asawa, T. Saito, A. Satoh, K. Ohtake, T. Tsuchiya, and H. Okada Participation of bone marrow cells in biliary fibrosis after bile duct ligation J Gastroenterol Hepatol 22 2007 2001 2008
-
(2007)
J Gastroenterol Hepatol
, vol.22
, pp. 2001-2008
-
-
Asawa, S.1
Saito, T.2
Satoh, A.3
Ohtake, K.4
Tsuchiya, T.5
Okada, H.6
-
168
-
-
68949101364
-
Fibrogenic potential of human multipotent mesenchymal stromal cells in injured liver
-
R.M. Baertschiger, V. Serre-Beinier, P. Morel, D. Bosco, M. Peyrou, and S. Clement Fibrogenic potential of human multipotent mesenchymal stromal cells in injured liver PLoS ONE 4 2009 e6657
-
(2009)
PLoS ONE
, vol.4
, pp. 6657
-
-
Baertschiger, R.M.1
Serre-Beinier, V.2
Morel, P.3
Bosco, D.4
Peyrou, M.5
Clement, S.6
-
169
-
-
70349432262
-
The promise of advanced imaging techniques for the detection of hepatitis C virus antigens in the infected liver
-
B. Wolk, and D. Moradpour The promise of advanced imaging techniques for the detection of hepatitis C virus antigens in the infected liver Gastroenterology 137 2009 1214 1218
-
(2009)
Gastroenterology
, vol.137
, pp. 1214-1218
-
-
Wolk, B.1
Moradpour, D.2
-
170
-
-
77950612565
-
The epithelial-to-mesenchymal transition in liver fibrosis: Here today, gone tomorrow?
-
R.G. Wells The epithelial-to-mesenchymal transition in liver fibrosis: here today, gone tomorrow? Hepatology 51 3 2010 737 740
-
(2010)
Hepatology
, vol.51
, Issue.3
, pp. 737-740
-
-
Wells, R.G.1
-
171
-
-
67650999875
-
The basics of epithelialmesenchymal transition
-
R. Kalluri, and R.A. Weinberg The basics of epithelialmesenchymal transition J Clin Invest 119 2009 1420 1428
-
(2009)
J Clin Invest
, vol.119
, pp. 1420-1428
-
-
Kalluri, R.1
Weinberg, R.A.2
-
172
-
-
67650996280
-
Epithelialmesenchymal transitions: The importance of changing cell state in development and disease
-
H. Acloque, M.S. Adams, K. Fishwick, M. Bronner-Fraser, and M.A. Nieto Epithelialmesenchymal transitions: the importance of changing cell state in development and disease J Clin Invest 119 2009 1438 1449
-
(2009)
J Clin Invest
, vol.119
, pp. 1438-1449
-
-
Acloque, H.1
Adams, M.S.2
Fishwick, K.3
Bronner-Fraser, M.4
Nieto, M.A.5
-
173
-
-
0036322007
-
Evidence that fibroblasts derive from epithelium during tissue fibrosis
-
M. Iwano, D. Plieth, T.M. Danoff, C. Xue, H. Okada, and E.G. Neilson Evidence that fibroblasts derive from epithelium during tissue fibrosis J Clin Invest 110 2002 341 350
-
(2002)
J Clin Invest
, vol.110
, pp. 341-350
-
-
Iwano, M.1
Plieth, D.2
Danoff, T.M.3
Xue, C.4
Okada, H.5
Neilson, E.G.6
-
174
-
-
34548411746
-
TGF-beta-induced EMT: Mechanisms and implications for fibrotic lung disease
-
B.C. Willis, and Z. Borok TGF-beta-induced EMT: mechanisms and implications for fibrotic lung disease Am J Physiol Lung Cell Mol Physiol 293 2007 L525 L534
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.293
-
-
Willis, B.C.1
Borok, Z.2
-
175
-
-
34547599359
-
Transforming growth factor-beta1 induces an epithelial-to-mesenchymal transition state in mouse hepatocytes in vitro
-
A. Kaimori, J. Potter, J.Y. Kaimori, C. Wang, E. Mezey, and A. Koteish Transforming growth factor-beta1 induces an epithelial-to-mesenchymal transition state in mouse hepatocytes in vitro J Biol Chem 282 2007 22089 22101
-
(2007)
J Biol Chem
, vol.282
, pp. 22089-22101
-
-
Kaimori, A.1
Potter, J.2
Kaimori, J.Y.3
Wang, C.4
Mezey, E.5
Koteish, A.6
-
176
-
-
34548145815
-
Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition
-
M. Zeisberg, C. Yang, M. Martino, M.B. Duncan, F. Rieder, and H. Tanjore Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition J Biol Chem 282 2007 23337 23347
-
(2007)
J Biol Chem
, vol.282
, pp. 23337-23347
-
-
Zeisberg, M.1
Yang, C.2
Martino, M.3
Duncan, M.B.4
Rieder, F.5
Tanjore, H.6
-
177
-
-
51349133312
-
Murine cirrhosis induces hepatocyte epithelial mesenchymal transition and alterations in survival signaling pathways
-
T. Nitta, J.S. Kim, D. Mohuczy, and K.E. Behrns Murine cirrhosis induces hepatocyte epithelial mesenchymal transition and alterations in survival signaling pathways Hepatology 48 2008 909 919
-
(2008)
Hepatology
, vol.48
, pp. 909-919
-
-
Nitta, T.1
Kim, J.S.2
Mohuczy, D.3
Behrns, K.E.4
-
178
-
-
77950597707
-
Hepatocytes do not undergo epithelialmesenchymal transition in liver fibrosis in mice
-
K. Taura, K. Miura, K. Iwaisako, C.H. Osterreicher, Y. Kodama, and M. Penz-Osterreicher Hepatocytes do not undergo epithelialmesenchymal transition in liver fibrosis in mice Hepatology 51 2010 1027 1036
-
(2010)
Hepatology
, vol.51
, pp. 1027-1036
-
-
Taura, K.1
Miura, K.2
Iwaisako, K.3
Osterreicher, C.H.4
Kodama, Y.5
Penz-Osterreicher, M.6
-
179
-
-
36749026566
-
Evidence for the epithelial to mesenchymal transition in biliary atresia fibrosis
-
R. Diaz, J.W. Kim, J.J. Hui, Z. Li, G.P. Swain, and K.S. Fong Evidence for the epithelial to mesenchymal transition in biliary atresia fibrosis Hum Pathol 39 2008 102 115
-
(2008)
Hum Pathol
, vol.39
, pp. 102-115
-
-
Diaz, R.1
Kim, J.W.2
Hui, J.J.3
Li, Z.4
Swain, G.P.5
Fong, K.S.6
-
180
-
-
38549143883
-
Epithelialmesenchymal transition contributes to portal tract fibrogenesis during human chronic liver disease
-
K.A. Rygiel, H. Robertson, H.L. Marshall, M. Pekalski, L. Zhao, and T.A. Booth Epithelialmesenchymal transition contributes to portal tract fibrogenesis during human chronic liver disease Lab Invest 88 2008 112 123
-
(2008)
Lab Invest
, vol.88
, pp. 112-123
-
-
Rygiel, K.A.1
Robertson, H.2
Marshall, H.L.3
Pekalski, M.4
Zhao, L.5
Booth, T.A.6
-
181
-
-
34247334927
-
Biliary epithelialmesenchymal transition in posttransplantation recurrence of primary biliary cirrhosis
-
H. Robertson, J.A. Kirby, W.W. Yip, D.E. Jones, and A.D. Burt Biliary epithelialmesenchymal transition in posttransplantation recurrence of primary biliary cirrhosis Hepatology 45 2007 977 981
-
(2007)
Hepatology
, vol.45
, pp. 977-981
-
-
Robertson, H.1
Kirby, J.A.2
Yip, W.W.3
Jones, D.E.4
Burt, A.D.5
-
182
-
-
55849135600
-
Hedgehog signaling regulates epithelialmesenchymal transition during biliary fibrosis in rodents and humans
-
A. Omenetti, A. Porrello, Y. Jung, L. Yang, Y. Popov, and S.S. Choi Hedgehog signaling regulates epithelialmesenchymal transition during biliary fibrosis in rodents and humans J Clin Invest 118 2008 3331 3342
-
(2008)
J Clin Invest
, vol.118
, pp. 3331-3342
-
-
Omenetti, A.1
Porrello, A.2
Jung, Y.3
Yang, L.4
Popov, Y.5
Choi, S.S.6
-
183
-
-
33645765320
-
De-differentiation of primary human hepatocytes depends on the composition of specialized liver basement membrane
-
M. Zeisberg, K. Kramer, N. Sindhi, P. Sarkar, M. Upton, and R. Kalluri De-differentiation of primary human hepatocytes depends on the composition of specialized liver basement membrane Mol Cell Biochem 283 2006 181 189
-
(2006)
Mol Cell Biochem
, vol.283
, pp. 181-189
-
-
Zeisberg, M.1
Kramer, K.2
Sindhi, N.3
Sarkar, P.4
Upton, M.5
Kalluri, R.6
-
184
-
-
0033874135
-
Transforming growth factor-beta initiates wound repair in rat liver through induction of the EIIIA-fibronectin splice isoform
-
J. George, S.S. Wang, A.M. Sevcsik, M. Sanicola, R.L. Cate, and V.E. Koteliansky Transforming growth factor-beta initiates wound repair in rat liver through induction of the EIIIA-fibronectin splice isoform Am J Pathol 156 2000 115 124
-
(2000)
Am J Pathol
, vol.156
, pp. 115-124
-
-
George, J.1
Wang, S.S.2
Sevcsik, A.M.3
Sanicola, M.4
Cate, R.L.5
Koteliansky, V.E.6
-
185
-
-
0027051397
-
Rat hepatocytes in primary culture synthesize and secrete cellular fibronectin
-
M. Odenthal, K. Neubauer, F.E. Baralle, H. Peters, K.H. Meyer zum Buschenfelde, and G. Ramadori Rat hepatocytes in primary culture synthesize and secrete cellular fibronectin Exp Cell Res 203 1992 289 296
-
(1992)
Exp Cell Res
, vol.203
, pp. 289-296
-
-
Odenthal, M.1
Neubauer, K.2
Baralle, F.E.3
Peters, H.4
Meyer Zum Buschenfelde, K.H.5
Ramadori, G.6
-
186
-
-
0026756029
-
Synthesis of cellular fibronectin by rat liver fat-storing (Ito) cells: Regulation by cytokines
-
G. Ramadori, T. Knittel, M. Odenthal, S. Schwogler, K. Neubauer, and K.H. Meyer zum Buschenfelde Synthesis of cellular fibronectin by rat liver fat-storing (Ito) cells: regulation by cytokines Gastroenterology 103 1992 1313 1321
-
(1992)
Gastroenterology
, vol.103
, pp. 1313-1321
-
-
Ramadori, G.1
Knittel, T.2
Odenthal, M.3
Schwogler, S.4
Neubauer, K.5
Meyer Zum Buschenfelde, K.H.6
-
187
-
-
0030798512
-
Gene expression and synthesis of fibronectin isoforms in rat hepatic stellate cells. Comparison with liver parenchymal cells and skin fibroblasts
-
G. Xu, T. Niki, I. Virtanen, V. Rogiers, P. De Bleser, and A. Geerts Gene expression and synthesis of fibronectin isoforms in rat hepatic stellate cells. Comparison with liver parenchymal cells and skin fibroblasts J Pathol 183 1997 90 98
-
(1997)
J Pathol
, vol.183
, pp. 90-98
-
-
Xu, G.1
Niki, T.2
Virtanen, I.3
Rogiers, V.4
De Bleser, P.5
Geerts, A.6
-
188
-
-
13744255589
-
Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair
-
J.S. Duffield, S.J. Forbes, C.M. Constandinou, S. Clay, M. Partolina, and S. Vuthoori Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair J Clin Invest 115 2005 56 65
-
(2005)
J Clin Invest
, vol.115
, pp. 56-65
-
-
Duffield, J.S.1
Forbes, S.J.2
Constandinou, C.M.3
Clay, S.4
Partolina, M.5
Vuthoori, S.6
-
189
-
-
0030615201
-
Nuclear factor-kappaB: A pivotal transcription factor in chronic inflammatory diseases
-
P.J. Barnes, and M. Karin Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases N Engl J Med 336 1997 1066 1071
-
(1997)
N Engl J Med
, vol.336
, pp. 1066-1071
-
-
Barnes, P.J.1
Karin, M.2
-
190
-
-
17844386319
-
IKKalpha limits macrophage NF-kappaB activation and contributes to the resolution of inflammation
-
T. Lawrence, M. Bebien, G.Y. Liu, V. Nizet, and M. Karin IKKalpha limits macrophage NF-kappaB activation and contributes to the resolution of inflammation Nature 434 2005 1138 1143
-
(2005)
Nature
, vol.434
, pp. 1138-1143
-
-
Lawrence, T.1
Bebien, M.2
Liu, G.Y.3
Nizet, V.4
Karin, M.5
-
191
-
-
0025272893
-
Stimulation of hepatic lipocyte collagen production by Kupffer cell-derived transforming growth factor beta: Implication for a pathogenetic role in alcoholic liver fibrogenesis
-
M. Matsuoka, and H. Tsukamoto Stimulation of hepatic lipocyte collagen production by Kupffer cell-derived transforming growth factor beta: implication for a pathogenetic role in alcoholic liver fibrogenesis Hepatology 11 1990 599 605
-
(1990)
Hepatology
, vol.11
, pp. 599-605
-
-
Matsuoka, M.1
Tsukamoto, H.2
-
192
-
-
0024852111
-
Activation of cultured rat hepatic lipocytes by Kupffer cell conditioned medium. Direct enhancement of matrix synthesis and stimulation of cell proliferation via induction of platelet-derived growth factor receptors
-
S.L. Friedman, and M.J. Arthur Activation of cultured rat hepatic lipocytes by Kupffer cell conditioned medium. Direct enhancement of matrix synthesis and stimulation of cell proliferation via induction of platelet-derived growth factor receptors J Clin Invest 84 1989 1780 1785
-
(1989)
J Clin Invest
, vol.84
, pp. 1780-1785
-
-
Friedman, S.L.1
Arthur, M.J.2
-
193
-
-
2942592246
-
Enhancer-mediated control of macrophage-specific arginase i expression
-
A.L. Pauleau, R. Rutschman, R. Lang, A. Pernis, S.S. Watowich, and P.J. Murray Enhancer-mediated control of macrophage-specific arginase I expression J Immunol 172 2004 7565 7573
-
(2004)
J Immunol
, vol.172
, pp. 7565-7573
-
-
Pauleau, A.L.1
Rutschman, R.2
Lang, R.3
Pernis, A.4
Watowich, S.S.5
Murray, P.J.6
-
194
-
-
0141989767
-
Global gene expression profiles during acute pathogen-induced pulmonary inflammation reveal divergent roles for Th1 and Th2 responses in tissue repair
-
N.G. Sandler, M.M. Mentink-Kane, A.W. Cheever, and T.A. Wynn Global gene expression profiles during acute pathogen-induced pulmonary inflammation reveal divergent roles for Th1 and Th2 responses in tissue repair J Immunol 171 2003 3655 3667
-
(2003)
J Immunol
, vol.171
, pp. 3655-3667
-
-
Sandler, N.G.1
Mentink-Kane, M.M.2
Cheever, A.W.3
Wynn, T.A.4
-
195
-
-
0034614343
-
Enhanced interstitial collagenase (matrix metalloproteinase-13) production of Kupffer cell by gadolinium chloride prevents pig serum-induced rat liver fibrosis
-
K. Hironaka, I. Sakaida, Y. Matsumura, S. Kaino, K. Miyamoto, and K. Okita Enhanced interstitial collagenase (matrix metalloproteinase-13) production of Kupffer cell by gadolinium chloride prevents pig serum-induced rat liver fibrosis Biochem Biophys Res Commun 267 2000 290 295
-
(2000)
Biochem Biophys Res Commun
, vol.267
, pp. 290-295
-
-
Hironaka, K.1
Sakaida, I.2
Matsumura, Y.3
Kaino, S.4
Miyamoto, K.5
Okita, K.6
-
196
-
-
0037268098
-
Mutation in collagen-1 that confers resistance to the action of collagenase results in failure of recovery from CCl4-induced liver fibrosis, persistence of activated hepatic stellate cells, and diminished hepatocyte regeneration
-
R. Issa, X. Zhou, N. Trim, H. Millward-Sadler, S. Krane, and C. Benyon Mutation in collagen-1 that confers resistance to the action of collagenase results in failure of recovery from CCl4-induced liver fibrosis, persistence of activated hepatic stellate cells, and diminished hepatocyte regeneration FASEB J 17 2003 47 49
-
(2003)
FASEB J
, vol.17
, pp. 47-49
-
-
Issa, R.1
Zhou, X.2
Trim, N.3
Millward-Sadler, H.4
Krane, S.5
Benyon, C.6
-
197
-
-
0036724910
-
Caspase 9-dependent killing of hepatic stellate cells by activated Kupffer cells
-
R. Fischer, A. Cariers, R. Reinehr, and D. Haussinger Caspase 9-dependent killing of hepatic stellate cells by activated Kupffer cells Gastroenterology 123 2002 845 861
-
(2002)
Gastroenterology
, vol.123
, pp. 845-861
-
-
Fischer, R.1
Cariers, A.2
Reinehr, R.3
Haussinger, D.4
-
198
-
-
1842290928
-
Differences in angiogenic potential of classically vs alternatively activated macrophages
-
V. Kodelja, C. Muller, S. Tenorio, C. Schebesch, C.E. Orfanos, and S. Goerdt Differences in angiogenic potential of classically vs alternatively activated macrophages Immunobiology 197 1997 478 493
-
(1997)
Immunobiology
, vol.197
, pp. 478-493
-
-
Kodelja, V.1
Muller, C.2
Tenorio, S.3
Schebesch, C.4
Orfanos, C.E.5
Goerdt, S.6
-
199
-
-
0037199425
-
Macrophage depletion by clodronate-containing liposomes reduces neointimal formation after balloon injury in rats and rabbits
-
H.D. Danenberg, I. Fishbein, J. Gao, J. Monkkonen, R. Reich, and I. Gati Macrophage depletion by clodronate-containing liposomes reduces neointimal formation after balloon injury in rats and rabbits Circulation 106 2002 599 605
-
(2002)
Circulation
, vol.106
, pp. 599-605
-
-
Danenberg, H.D.1
Fishbein, I.2
Gao, J.3
Monkkonen, J.4
Reich, R.5
Gati, I.6
-
200
-
-
0034530747
-
A critical role for alveolar macrophages in elicitation of pulmonary immune fibrosis
-
J. Zhang-Hoover, A. Sutton, N. van Rooijen, and J. Stein-Streilein A critical role for alveolar macrophages in elicitation of pulmonary immune fibrosis Immunology 101 2000 501 511
-
(2000)
Immunology
, vol.101
, pp. 501-511
-
-
Zhang-Hoover, J.1
Sutton, A.2
Van Rooijen, N.3
Stein-Streilein, J.4
-
201
-
-
0023726231
-
Deactivation of macrophages by transforming growth factor-beta
-
S. Tsunawaki, M. Sporn, A. Ding, and C. Nathan Deactivation of macrophages by transforming growth factor-beta Nature 334 1988 260 262
-
(1988)
Nature
, vol.334
, pp. 260-262
-
-
Tsunawaki, S.1
Sporn, M.2
Ding, A.3
Nathan, C.4
-
202
-
-
0030782158
-
Macrophages induce apoptosis in normal cells in vivo
-
G. Diez-Roux, and R.A. Lang Macrophages induce apoptosis in normal cells in vivo Development 124 1997 3633 3638
-
(1997)
Development
, vol.124
, pp. 3633-3638
-
-
Diez-Roux, G.1
Lang, R.A.2
-
203
-
-
0031883604
-
Increased expression of interleukin-6 and tumor necrosis factor-alpha in pathologic biliary epithelial cells: In situ and culture study
-
M. Yasoshima, N. Kono, H. Sugawara, K. Katayanagi, K. Harada, and Y. Nakanuma Increased expression of interleukin-6 and tumor necrosis factor-alpha in pathologic biliary epithelial cells: in situ and culture study Lab Invest 78 1998 89 100
-
(1998)
Lab Invest
, vol.78
, pp. 89-100
-
-
Yasoshima, M.1
Kono, N.2
Sugawara, H.3
Katayanagi, K.4
Harada, K.5
Nakanuma, Y.6
-
204
-
-
0031883173
-
Increased expression of monocyte chemotactic protein-1 during active hepatic fibrogenesis: Correlation with monocyte infiltration
-
F. Marra, R. DeFranco, C. Grappone, S. Milani, S. Pastacaldi, and M. Pinzani Increased expression of monocyte chemotactic protein-1 during active hepatic fibrogenesis: correlation with monocyte infiltration Am J Pathol 152 1998 423 430
-
(1998)
Am J Pathol
, vol.152
, pp. 423-430
-
-
Marra, F.1
Defranco, R.2
Grappone, C.3
Milani, S.4
Pastacaldi, S.5
Pinzani, M.6
-
205
-
-
0036484205
-
Peribiliary myofibroblasts in biliary type liver fibrosis
-
N. Kinnman, and C. Housset Peribiliary myofibroblasts in biliary type liver fibrosis Front Biosci 7 2002 d496 d503
-
(2002)
Front Biosci
, vol.7
-
-
Kinnman, N.1
Housset, C.2
-
206
-
-
0035066961
-
Proliferating bile duct epithelial cells are a major source of connective tissue growth factor in rat biliary fibrosis
-
N. Sedlaczek, J.D. Jia, M. Bauer, H. Herbst, M. Ruehl, and E.G. Hahn Proliferating bile duct epithelial cells are a major source of connective tissue growth factor in rat biliary fibrosis Am J Pathol 158 2001 1239 1244
-
(2001)
Am J Pathol
, vol.158
, pp. 1239-1244
-
-
Sedlaczek, N.1
Jia, J.D.2
Bauer, M.3
Herbst, H.4
Ruehl, M.5
Hahn, E.G.6
-
207
-
-
33845644601
-
STAT1 inhibits liver fibrosis in mice by inhibiting stellate cell proliferation and stimulating NK cell cytotoxicity
-
W.I. Jeong, O. Park, S. Radaeva, and B. Gao STAT1 inhibits liver fibrosis in mice by inhibiting stellate cell proliferation and stimulating NK cell cytotoxicity Hepatology 44 2006 1441 1451
-
(2006)
Hepatology
, vol.44
, pp. 1441-1451
-
-
Jeong, W.I.1
Park, O.2
Radaeva, S.3
Gao, B.4
-
208
-
-
33744939234
-
Anti-fibrotic activity of NK cells in experimental liver injury through killing of activated HSC
-
A. Melhem, N. Muhanna, A. Bishara, C.E. Alvarez, Y. Ilan, and T. Bishara Anti-fibrotic activity of NK cells in experimental liver injury through killing of activated HSC J Hepatol 45 2006 60 71
-
(2006)
J Hepatol
, vol.45
, pp. 60-71
-
-
Melhem, A.1
Muhanna, N.2
Bishara, A.3
Alvarez, C.E.4
Ilan, Y.5
Bishara, T.6
-
209
-
-
33645231470
-
Decreased NK cell frequency in chronic hepatitis C does not affect ex vivo cytolytic killing
-
C. Morishima, D.M. Paschal, C.C. Wang, C.S. Yoshihara, B.L. Wood, and A.E. Yeo Decreased NK cell frequency in chronic hepatitis C does not affect ex vivo cytolytic killing Hepatology 43 2006 573 580
-
(2006)
Hepatology
, vol.43
, pp. 573-580
-
-
Morishima, C.1
Paschal, D.M.2
Wang, C.C.3
Yoshihara, C.S.4
Wood, B.L.5
Yeo, A.E.6
-
210
-
-
32044463137
-
Activation-induced cell death of hepatic stellate cells by the innate immune system
-
W.Z. Mehal Activation-induced cell death of hepatic stellate cells by the innate immune system Gastroenterology 130 2006 600 603
-
(2006)
Gastroenterology
, vol.130
, pp. 600-603
-
-
Mehal, W.Z.1
-
211
-
-
32044443617
-
Natural killer cells ameliorate liver fibrosis by killing activated stellate cells in NKG2D-dependent and tumor necrosis factor-related apoptosis-inducing ligand-dependent manners
-
S. Radaeva, R. Sun, B. Jaruga, V.T. Nguyen, Z. Tian, and B. Gao Natural killer cells ameliorate liver fibrosis by killing activated stellate cells in NKG2D-dependent and tumor necrosis factor-related apoptosis-inducing ligand-dependent manners Gastroenterology 130 2006 435 452
-
(2006)
Gastroenterology
, vol.130
, pp. 435-452
-
-
Radaeva, S.1
Sun, R.2
Jaruga, B.3
Nguyen, V.T.4
Tian, Z.5
Gao, B.6
-
212
-
-
40749087701
-
Innate immunity and alcoholic liver fibrosis
-
W.I. Jeong, and B. Gao Innate immunity and alcoholic liver fibrosis J Gastroenterol Hepatol 23 Suppl. 1 2008 S112 S118
-
(2008)
J Gastroenterol Hepatol
, vol.23
, Issue.SUPPL. 1
-
-
Jeong, W.I.1
Gao, B.2
-
213
-
-
33645973988
-
Attenuated liver fibrosis in the absence of B cells
-
A.P. Holt, Z. Stamataki, and D.H. Adams Attenuated liver fibrosis in the absence of B cells Hepatology 43 2006 868 871
-
(2006)
Hepatology
, vol.43
, pp. 868-871
-
-
Holt, A.P.1
Stamataki, Z.2
Adams, D.H.3
-
214
-
-
27644501080
-
Attenuated liver fibrosis in the absence of B cells
-
T.I. Novobrantseva, G.R. Majeau, A. Amatucci, S. Kogan, I. Brenner, and S. Casola Attenuated liver fibrosis in the absence of B cells J Clin Invest 115 2005 3072 3082
-
(2005)
J Clin Invest
, vol.115
, pp. 3072-3082
-
-
Novobrantseva, T.I.1
Majeau, G.R.2
Amatucci, A.3
Kogan, S.4
Brenner, I.5
Casola, S.6
-
215
-
-
0032697042
-
An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response
-
M.G. Chiaramonte, D.D. Donaldson, A.W. Cheever, and T.A. Wynn An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response J Clin Invest 104 1999 777 785
-
(1999)
J Clin Invest
, vol.104
, pp. 777-785
-
-
Chiaramonte, M.G.1
Donaldson, D.D.2
Cheever, A.W.3
Wynn, T.A.4
-
216
-
-
0030885185
-
Strain-specific differences in mouse hepatic wound healing are mediated by divergent T helper cytokine responses
-
Z. Shi, A.E. Wakil, and D.C. Rockey Strain-specific differences in mouse hepatic wound healing are mediated by divergent T helper cytokine responses Proc Natl Acad Sci USA 94 1997 10663 10668
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 10663-10668
-
-
Shi, Z.1
Wakil, A.E.2
Rockey, D.C.3
-
217
-
-
0038637369
-
Factor v Leiden polymorphism and the rate of fibrosis development in chronic hepatitis C virus infection
-
M. Wright, R. Goldin, S. Hellier, S. Knapp, A. Frodsham, and B. Hennig Factor V Leiden polymorphism and the rate of fibrosis development in chronic hepatitis C virus infection Gut 52 2003 1206 1210
-
(2003)
Gut
, vol.52
, pp. 1206-1210
-
-
Wright, M.1
Goldin, R.2
Hellier, S.3
Knapp, S.4
Frodsham, A.5
Hennig, B.6
-
218
-
-
0037369783
-
Thrombotic risk factors and extent of liver fibrosis in chronic viral hepatitis
-
G.V. Papatheodoridis, E. Papakonstantinou, E. Andrioti, E. Cholongitas, K. Petraki, and I. Kontopoulou Thrombotic risk factors and extent of liver fibrosis in chronic viral hepatitis Gut 52 2003 404 409
-
(2003)
Gut
, vol.52
, pp. 404-409
-
-
Papatheodoridis, G.V.1
Papakonstantinou, E.2
Andrioti, E.3
Cholongitas, E.4
Petraki, K.5
Kontopoulou, I.6
-
219
-
-
47649093322
-
Coagulation status modulates murine hepatic fibrogenesis: Implications for the development of novel therapies
-
Q.M. Anstee, R.D. Goldin, M. Wright, A. Martinelli, R. Cox, and M.R. Thursz Coagulation status modulates murine hepatic fibrogenesis: implications for the development of novel therapies J Thromb Haemost 6 2008 1336 1343
-
(2008)
J Thromb Haemost
, vol.6
, pp. 1336-1343
-
-
Anstee, Q.M.1
Goldin, R.D.2
Wright, M.3
Martinelli, A.4
Cox, R.5
Thursz, M.R.6
-
220
-
-
30744437415
-
Platelets mediate cytotoxic T lymphocyte-induced liver damage
-
M. Iannacone, G. Sitia, M. Isogawa, P. Marchese, M.G. Castro, and P.R. Lowenstein Platelets mediate cytotoxic T lymphocyte-induced liver damage Nat Med 11 2005 1167 1169
-
(2005)
Nat Med
, vol.11
, pp. 1167-1169
-
-
Iannacone, M.1
Sitia, G.2
Isogawa, M.3
Marchese, P.4
Castro, M.G.5
Lowenstein, P.R.6
-
221
-
-
46749155479
-
Aggravation of viral hepatitis by platelet-derived serotonin
-
P.A. Lang, C. Contaldo, P. Georgiev, A.M. El-Badry, M. Recher, and M. Kurrer Aggravation of viral hepatitis by platelet-derived serotonin Nat Med 14 2008 756 761
-
(2008)
Nat Med
, vol.14
, pp. 756-761
-
-
Lang, P.A.1
Contaldo, C.2
Georgiev, P.3
El-Badry, A.M.4
Recher, M.5
Kurrer, M.6
-
222
-
-
33645666489
-
Platelet-derived serotonin mediates liver regeneration
-
M. Lesurtel, R. Graf, B. Aleil, D.J. Walther, Y. Tian, and W. Jochum Platelet-derived serotonin mediates liver regeneration Science 312 2006 104 107
-
(2006)
Science
, vol.312
, pp. 104-107
-
-
Lesurtel, M.1
Graf, R.2
Aleil, B.3
Walther, D.J.4
Tian, Y.5
Jochum, W.6
-
223
-
-
77950620236
-
CXC chemokine ligand 4 (Cxcl4) is a platelet-derived mediator of experimental liver fibrosis
-
M.M. Zaldivar, K. Pauels, P. von Hundelshausen, M.L. Berres, P. Schmitz, and J. Bornemann CXC chemokine ligand 4 (Cxcl4) is a platelet-derived mediator of experimental liver fibrosis Hepatology 51 2010 1345 1353
-
(2010)
Hepatology
, vol.51
, pp. 1345-1353
-
-
Zaldivar, M.M.1
Pauels, K.2
Von Hundelshausen, P.3
Berres, M.L.4
Schmitz, P.5
Bornemann, J.6
-
224
-
-
77952737960
-
Thrombocytopenia exacerbates cholestasis-induced liver fibrosis in mice
-
T. Kodama, T. Takehara, H. Hikita, S. Shimizu, W. Li, and T. Miyagi Thrombocytopenia exacerbates cholestasis-induced liver fibrosis in mice Gastroenterology 138 7 2010 2487 2498 2498.e1-7
-
(2010)
Gastroenterology
, vol.138
, Issue.7
, pp. 2487-2498
-
-
Kodama, T.1
Takehara, T.2
Hikita, H.3
Shimizu, S.4
Li, W.5
Miyagi, T.6
-
225
-
-
33847747457
-
Platelets and platelet-derived serotonin promote tissue repair after normothermic hepatic ischemia in mice
-
A. Nocito, P. Georgiev, F. Dahm, W. Jochum, M. Bader, and R. Graf Platelets and platelet-derived serotonin promote tissue repair after normothermic hepatic ischemia in mice Hepatology 45 2007 369 376
-
(2007)
Hepatology
, vol.45
, pp. 369-376
-
-
Nocito, A.1
Georgiev, P.2
Dahm, F.3
Jochum, W.4
Bader, M.5
Graf, R.6
-
226
-
-
33644828391
-
Development of dendritic cell system
-
L. Wu, and A. Dakic Development of dendritic cell system Cell Mol Immunol 1 2004 112 118
-
(2004)
Cell Mol Immunol
, vol.1
, pp. 112-118
-
-
Wu, L.1
Dakic, A.2
-
227
-
-
33750934617
-
Dendritic cells: Translating innate to adaptive immunity
-
R.M. Steinman, and H. Hemmi Dendritic cells: translating innate to adaptive immunity Curr Top Microbiol Immunol 311 2006 17 58
-
(2006)
Curr Top Microbiol Immunol
, vol.311
, pp. 17-58
-
-
Steinman, R.M.1
Hemmi, H.2
-
228
-
-
33747345457
-
Receptors and ligands involved in viral induction of type i interferon production by plasmacytoid dendritic cells
-
R.E. Seeds, S. Gordon, and J.L. Miller Receptors and ligands involved in viral induction of type I interferon production by plasmacytoid dendritic cells Immunobiology 211 2006 525 535
-
(2006)
Immunobiology
, vol.211
, pp. 525-535
-
-
Seeds, R.E.1
Gordon, S.2
Miller, J.L.3
-
229
-
-
33645302098
-
Characterization of human liver dendritic cells in liver grafts and perfusates
-
B.M. Bosma, H.J. Metselaar, S. Mancham, P.P. Boor, J.G. Kusters, and G. Kazemier Characterization of human liver dendritic cells in liver grafts and perfusates Liver Transpl 12 2006 384 393
-
(2006)
Liver Transpl
, vol.12
, pp. 384-393
-
-
Bosma, B.M.1
Metselaar, H.J.2
Mancham, S.3
Boor, P.P.4
Kusters, J.G.5
Kazemier, G.6
-
230
-
-
33846951514
-
Emerging insights into transforming growth factor beta Smad signal in hepatic fibrogenesis
-
Y. Inagaki, and I. Okazaki Emerging insights into transforming growth factor beta Smad signal in hepatic fibrogenesis Gut 56 2007 284 292
-
(2007)
Gut
, vol.56
, pp. 284-292
-
-
Inagaki, Y.1
Okazaki, I.2
-
231
-
-
0036724907
-
Cell adhesion regulates platelet-derived growth factor-induced MAP kinase and PI-3 kinase activation in stellate cells
-
V. Carloni, R.M. Defranco, A. Caligiuri, A. Gentilini, S.C. Sciammetta, and E. Baldi Cell adhesion regulates platelet-derived growth factor-induced MAP kinase and PI-3 kinase activation in stellate cells Hepatology 36 2002 582 591
-
(2002)
Hepatology
, vol.36
, pp. 582-591
-
-
Carloni, V.1
Defranco, R.M.2
Caligiuri, A.3
Gentilini, A.4
Sciammetta, S.C.5
Baldi, E.6
-
232
-
-
0028140282
-
Expression of platelet-derived growth factor in a model of acute liver injury
-
M. Pinzani, S. Milani, C. Grappone, F.L.J. Weber, P. Gentilini, and H.E. Abboud Expression of platelet-derived growth factor in a model of acute liver injury Hepatology 19 1994 701 707
-
(1994)
Hepatology
, vol.19
, pp. 701-707
-
-
Pinzani, M.1
Milani, S.2
Grappone, C.3
Weber, F.L.J.4
Gentilini, P.5
Abboud, H.E.6
-
233
-
-
0028170153
-
Induction of beta-platelet-derived growth factor receptor in rat hepatic lipocytes during cellular activation in vivo and in culture
-
L. Wong, G. Yamasaki, R.J. Johnson, and S.L. Friedman Induction of beta-platelet-derived growth factor receptor in rat hepatic lipocytes during cellular activation in vivo and in culture J Clin Invest 94 1994 1563 1569
-
(1994)
J Clin Invest
, vol.94
, pp. 1563-1569
-
-
Wong, L.1
Yamasaki, G.2
Johnson, R.J.3
Friedman, S.L.4
-
234
-
-
0347986777
-
NADPH oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosis
-
R. Bataller, R.F. Schwabe, Y.H. Choi, L. Yang, Y.H. Paik, and J. Lindquist NADPH oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosis J Clin Invest 112 2003 1383 1394
-
(2003)
J Clin Invest
, vol.112
, pp. 1383-1394
-
-
Bataller, R.1
Schwabe, R.F.2
Choi, Y.H.3
Yang, L.4
Paik, Y.H.5
Lindquist, J.6
-
235
-
-
0034120267
-
Angiotensin II induces contraction and proliferation of human hepatic stellate cells
-
R. Bataller, P. Gines, J.M. Nicolas, M.N. Gorbig, E. Garcia-Ramallo, and X. Gasull Angiotensin II induces contraction and proliferation of human hepatic stellate cells Gastroenterology 118 2000 1149 1156
-
(2000)
Gastroenterology
, vol.118
, pp. 1149-1156
-
-
Bataller, R.1
Gines, P.2
Nicolas, J.M.3
Gorbig, M.N.4
Garcia-Ramallo, E.5
Gasull, X.6
-
236
-
-
0042009848
-
Prolonged infusion of angiotensin II into normal rats induces stellate cell activation and proinflammatory events in liver
-
R. Bataller, E. Gabele, R. Schoonhoven, T. Morris, M. Lehnert, and L. Yang Prolonged infusion of angiotensin II into normal rats induces stellate cell activation and proinflammatory events in liver Am J Physiol Gastrointest Liver Physiol 285 2003 G642 G651
-
(2003)
Am J Physiol Gastrointest Liver Physiol
, vol.285
-
-
Bataller, R.1
Gabele, E.2
Schoonhoven, R.3
Morris, T.4
Lehnert, M.5
Yang, L.6
-
237
-
-
54549098072
-
Cytokines and renin-angiotensin system signaling in hepatic fibrosis
-
M. Moreno, and R. Bataller Cytokines and renin-angiotensin system signaling in hepatic fibrosis Clin Liver Dis 12 2008 825 852 ix
-
(2008)
Clin Liver Dis
, vol.12
, pp. 825-852
-
-
Moreno, M.1
Bataller, R.2
-
238
-
-
30944469306
-
Adipokines in NASH: Postprandial lipid metabolism as a link between adiponectin and liver disease
-
G. Musso, R. Gambino, M. Durazzo, G. Biroli, M. Carello, and E. Faga Adipokines in NASH: postprandial lipid metabolism as a link between adiponectin and liver disease Hepatology 42 2005 1175 1183
-
(2005)
Hepatology
, vol.42
, pp. 1175-1183
-
-
Musso, G.1
Gambino, R.2
Durazzo, M.3
Biroli, G.4
Carello, M.5
Faga, E.6
-
239
-
-
10744228583
-
Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin
-
Y. Kamada, S. Tamura, S. Kiso, H. Matsumoto, Y. Saji, and Y. Yoshida Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin Gastroenterology 125 2003 1796 1807
-
(2003)
Gastroenterology
, vol.125
, pp. 1796-1807
-
-
Kamada, Y.1
Tamura, S.2
Kiso, S.3
Matsumoto, H.4
Saji, Y.5
Yoshida, Y.6
-
240
-
-
0036234147
-
Leptin receptor-mediated signaling regulates hepatic fibrogenesis and remodeling of extracellular matrix in the rat
-
K. Ikejima, Y. Takei, H. Honda, M. Hirose, M. Yoshikawa, and Y.J. Zhang Leptin receptor-mediated signaling regulates hepatic fibrogenesis and remodeling of extracellular matrix in the rat Gastroenterology 122 2002 1399 1410
-
(2002)
Gastroenterology
, vol.122
, pp. 1399-1410
-
-
Ikejima, K.1
Takei, Y.2
Honda, H.3
Hirose, M.4
Yoshikawa, M.5
Zhang, Y.J.6
-
241
-
-
0036022846
-
Leptin is essential for the hepatic fibrogenic response to chronic liver injury
-
I.A. Leclercq, G.C. Farrell, R. Schriemer, and G.R. Robertson Leptin is essential for the hepatic fibrogenic response to chronic liver injury J Hepatol 37 2002 206 213
-
(2002)
J Hepatol
, vol.37
, pp. 206-213
-
-
Leclercq, I.A.1
Farrell, G.C.2
Schriemer, R.3
Robertson, G.R.4
-
242
-
-
0038644530
-
Leptin induces increased alpha2(I) collagen gene expression in cultured rat hepatic stellate cells
-
N.K. Saxena, G. Saliba, J.J. Floyd, and F.A. Anania Leptin induces increased alpha2(I) collagen gene expression in cultured rat hepatic stellate cells J Cell Biochem 89 2003 311 320
-
(2003)
J Cell Biochem
, vol.89
, pp. 311-320
-
-
Saxena, N.K.1
Saliba, G.2
Floyd, J.J.3
Anania, F.A.4
-
244
-
-
0141706422
-
The chemokine CCL21 modulates lymphocyte recruitment and fibrosis in chronic hepatitis C
-
A. Bonacchi, I. Petrai, R.M. Defranco, E. Lazzeri, F. Annunziato, and E. Efsen The chemokine CCL21 modulates lymphocyte recruitment and fibrosis in chronic hepatitis C Gastroenterology 125 2003 1060 1076
-
(2003)
Gastroenterology
, vol.125
, pp. 1060-1076
-
-
Bonacchi, A.1
Petrai, I.2
Defranco, R.M.3
Lazzeri, E.4
Annunziato, F.5
Efsen, E.6
-
245
-
-
68849118799
-
CCR1 and CCR5 promote hepatic fibrosis in mice
-
E. Seki, S. De Minicis, G.Y. Gwak, J. Kluwe, S. Inokuchi, and C.A. Bursill CCR1 and CCR5 promote hepatic fibrosis in mice J Clin Invest 119 2009 1858 1870
-
(2009)
J Clin Invest
, vol.119
, pp. 1858-1870
-
-
Seki, E.1
De Minicis, S.2
Gwak, G.Y.3
Kluwe, J.4
Inokuchi, S.5
Bursill, C.A.6
-
246
-
-
67651156353
-
CCR2 promotes hepatic fibrosis in mice
-
E. Seki, S. de Minicis, S. Inokuchi, K. Taura, K. Miyai, and N. van Rooijen CCR2 promotes hepatic fibrosis in mice Hepatology 50 2009 185 197
-
(2009)
Hepatology
, vol.50
, pp. 185-197
-
-
Seki, E.1
De Minicis, S.2
Inokuchi, S.3
Taura, K.4
Miyai, K.5
Van Rooijen, N.6
-
247
-
-
67649183610
-
Antifibrotic effects of CXCL9 and its receptor CXCR3 in livers of mice and humans
-
H.E. Wasmuth, F. Lammert, M.M. Zaldivar, R. Weiskirchen, C. Hellerbrand, and D. Scholten Antifibrotic effects of CXCL9 and its receptor CXCR3 in livers of mice and humans Gastroenterology 137 1 2009 309 319.e3
-
(2009)
Gastroenterology
, vol.137
, Issue.1
-
-
Wasmuth, H.E.1
Lammert, F.2
Zaldivar, M.M.3
Weiskirchen, R.4
Hellerbrand, C.5
Scholten, D.6
-
248
-
-
0037424498
-
The role of focal adhesion kinase-phosphatidylinositol 3-kinase-akt signaling in hepatic stellate cell proliferation and type i collagen expression
-
S. Reif, A. Lang, J.N. Lindquist, Y. Yata, E. Gabele, and A. Scanga The role of focal adhesion kinase-phosphatidylinositol 3-kinase-akt signaling in hepatic stellate cell proliferation and type I collagen expression J Biol Chem 278 2003 8083 8090
-
(2003)
J Biol Chem
, vol.278
, pp. 8083-8090
-
-
Reif, S.1
Lang, A.2
Lindquist, J.N.3
Yata, Y.4
Gabele, E.5
Scanga, A.6
-
249
-
-
17144377431
-
The role of p70S6K in hepatic stellate cell collagen gene expression and cell proliferation
-
E. Gabele, S. Reif, S. Tsukada, R. Bataller, Y. Yata, and T. Morris The role of p70S6K in hepatic stellate cell collagen gene expression and cell proliferation J Biol Chem 280 2005 13374 13382
-
(2005)
J Biol Chem
, vol.280
, pp. 13374-13382
-
-
Gabele, E.1
Reif, S.2
Tsukada, S.3
Bataller, R.4
Yata, Y.5
Morris, T.6
-
250
-
-
42249084883
-
Alcohol and the liver
-
A. Reuben Alcohol and the liver Curr Opin Gastroenterol 24 2008 328 338
-
(2008)
Curr Opin Gastroenterol
, vol.24
, pp. 328-338
-
-
Reuben, A.1
-
251
-
-
0035336310
-
CD40 activates NF-kappa B and c-Jun N-terminal kinase and enhances chemokine secretion on activated human hepatic stellate cells
-
R.F. Schwabe, B. Schnabl, Y.O. Kweon, and D.A. Brenner CD40 activates NF-kappa B and c-Jun N-terminal kinase and enhances chemokine secretion on activated human hepatic stellate cells J Immunol 166 2001 6812 6819
-
(2001)
J Immunol
, vol.166
, pp. 6812-6819
-
-
Schwabe, R.F.1
Schnabl, B.2
Kweon, Y.O.3
Brenner, D.A.4
-
252
-
-
3042739914
-
Differential requirement for c-Jun NH2-terminal kinase in TNFalpha- and Fas-mediated apoptosis in hepatocytes
-
R.F. Schwabe, H. Uchinami, T. Qian, B.L. Bennett, J.J. Lemasters, and D.A. Brenner Differential requirement for c-Jun NH2-terminal kinase in TNFalpha- and Fas-mediated apoptosis in hepatocytes FASEB J 18 2004 720 722
-
(2004)
FASEB J
, vol.18
, pp. 720-722
-
-
Schwabe, R.F.1
Uchinami, H.2
Qian, T.3
Bennett, B.L.4
Lemasters, J.J.5
Brenner, D.A.6
-
253
-
-
0034756576
-
TAK1/JNK and p38 have opposite effects on rat hepatic stellate cells
-
B. Schnabl, C.A. Bradham, B.L. Bennett, A.M. Manning, B. Stefanovic, and D.A. Brenner TAK1/JNK and p38 have opposite effects on rat hepatic stellate cells Hepatology 34 2001 953 963
-
(2001)
Hepatology
, vol.34
, pp. 953-963
-
-
Schnabl, B.1
Bradham, C.A.2
Bennett, B.L.3
Manning, A.M.4
Stefanovic, B.5
Brenner, D.A.6
-
254
-
-
15444375634
-
SMAD and p38 MAPK signaling pathways independently regulate alpha1(I) collagen gene expression in unstimulated and transforming growth factor-beta-stimulated hepatic stellate cells
-
S. Tsukada, J.K. Westwick, K. Ikejima, N. Sato, and R.A. Rippe SMAD and p38 MAPK signaling pathways independently regulate alpha1(I) collagen gene expression in unstimulated and transforming growth factor-beta-stimulated hepatic stellate cells J Biol Chem 280 2005 10055 10064
-
(2005)
J Biol Chem
, vol.280
, pp. 10055-10064
-
-
Tsukada, S.1
Westwick, J.K.2
Ikejima, K.3
Sato, N.4
Rippe, R.A.5
-
256
-
-
0031868304
-
Cytokines induce NF-kappaB in activated but not in quiescent rat hepatic stellate cells
-
C. Hellerbrand, C. Jobin, L.L. Licato, R.B. Sartor, and D.A. Brenner Cytokines induce NF-kappaB in activated but not in quiescent rat hepatic stellate cells Am J Physiol 275 1998 G269 G278
-
(1998)
Am J Physiol
, vol.275
-
-
Hellerbrand, C.1
Jobin, C.2
Licato, L.L.3
Sartor, R.B.4
Brenner, D.A.5
-
257
-
-
0033623899
-
Nuclear factor kappaB in proliferation, activation, and apoptosis in rat hepatic stellate cells
-
A. Lang, R. Schoonhoven, S. Tuvia, D.A. Brenner, and R.A. Rippe Nuclear factor kappaB in proliferation, activation, and apoptosis in rat hepatic stellate cells J Hepatol 33 2000 49 58
-
(2000)
J Hepatol
, vol.33
, pp. 49-58
-
-
Lang, A.1
Schoonhoven, R.2
Tuvia, S.3
Brenner, D.A.4
Rippe, R.A.5
-
258
-
-
33645799492
-
Mechanisms of liver injury. I. TNF-alpha-induced liver injury: Role of IKK, JNK, and ROS pathways
-
R.F. Schwabe, and D.A. Brenner Mechanisms of liver injury. I. TNF-alpha-induced liver injury: role of IKK, JNK, and ROS pathways Am J Physiol Gastrointest Liver Physiol 290 2006 G583 G589
-
(2006)
Am J Physiol Gastrointest Liver Physiol
, vol.290
-
-
Schwabe, R.F.1
Brenner, D.A.2
-
259
-
-
42249093297
-
The role of matrix stiffness in regulating cell behavior
-
R.G. Wells The role of matrix stiffness in regulating cell behavior Hepatology 47 4 2008 1394 1400
-
(2008)
Hepatology
, vol.47
, Issue.4
, pp. 1394-1400
-
-
Wells, R.G.1
-
260
-
-
0034671734
-
Multiple binding sites in collagen type i for the integrins alpha1beta1 and alpha2beta1
-
Y. Xu, S. Gurusiddappa, R.L. Rich, R.T. Owens, D.R. Keene, and R. Mayne Multiple binding sites in collagen type I for the integrins alpha1beta1 and alpha2beta1 J Biol Chem 275 2000 38981 38989
-
(2000)
J Biol Chem
, vol.275
, pp. 38981-38989
-
-
Xu, Y.1
Gurusiddappa, S.2
Rich, R.L.3
Owens, R.T.4
Keene, D.R.5
Mayne, R.6
-
261
-
-
33646934768
-
Cytokines promote Wnt signaling and inflammation and impair the normal differentiation and lipid accumulation in 3T3-L1 preadipocytes
-
B. Gustafson, and U. Smith Cytokines promote Wnt signaling and inflammation and impair the normal differentiation and lipid accumulation in 3T3-L1 preadipocytes J Biol Chem 281 2006 9507 9516
-
(2006)
J Biol Chem
, vol.281
, pp. 9507-9516
-
-
Gustafson, B.1
Smith, U.2
-
262
-
-
0042855012
-
The CCN family: A new stimulus package
-
D.R. Brigstock The CCN family: a new stimulus package J Endocrinol 178 2003 169 175
-
(2003)
J Endocrinol
, vol.178
, pp. 169-175
-
-
Brigstock, D.R.1
-
263
-
-
34250207000
-
Wnt signaling enhances the activation and survival of human hepatic stellate cells
-
S.J. Myung, J.H. Yoon, G.Y. Gwak, W. Kim, J.H. Lee, and K.M. Kim Wnt signaling enhances the activation and survival of human hepatic stellate cells FEBS Lett 581 2007 2954 2958
-
(2007)
FEBS Lett
, vol.581
, pp. 2954-2958
-
-
Myung, S.J.1
Yoon, J.H.2
Gwak, G.Y.3
Kim, W.4
Lee, J.H.5
Kim, K.M.6
-
264
-
-
33746511526
-
Gene expression profile of quiescent and activated rat hepatic stellate cells implicates Wnt signaling pathway in activation
-
F. Jiang, C.J. Parsons, and B. Stefanovic Gene expression profile of quiescent and activated rat hepatic stellate cells implicates Wnt signaling pathway in activation J Hepatol 45 2006 401 409
-
(2006)
J Hepatol
, vol.45
, pp. 401-409
-
-
Jiang, F.1
Parsons, C.J.2
Stefanovic, B.3
-
265
-
-
38349091357
-
Wnt antagonism inhibits hepatic stellate cell activation and liver fibrosis
-
J.H. Cheng, H. She, Y.P. Han, J. Wang, S. Xiong, and K. Asahina Wnt antagonism inhibits hepatic stellate cell activation and liver fibrosis Am J Physiol Gastrointest Liver Physiol 294 2008 G39 G49
-
(2008)
Am J Physiol Gastrointest Liver Physiol
, vol.294
-
-
Cheng, J.H.1
She, H.2
Han, Y.P.3
Wang, J.4
Xiong, S.5
Asahina, K.6
-
266
-
-
64949101091
-
Down-regulation of Wnt signaling during apoptosis of human hepatic stellate cells
-
H.W. Shin, S.Y. Park, K.B. Lee, and J.J. Jang Down-regulation of Wnt signaling during apoptosis of human hepatic stellate cells Hepatogastroenterology 56 2009 208 212
-
(2009)
Hepatogastroenterology
, vol.56
, pp. 208-212
-
-
Shin, H.W.1
Park, S.Y.2
Lee, K.B.3
Jang, J.J.4
-
267
-
-
77952488262
-
Transcriptional profiling and Wnt signaling activation in proliferation of human hepatic stellate cells induced by PDGF-BB
-
H.W. Shin, S.Y. Park, K.B. Lee, E. Shin, S.W. Nam, and J.Y. Lee Transcriptional profiling and Wnt signaling activation in proliferation of human hepatic stellate cells induced by PDGF-BB Korean J Hepatol 15 2009 486 495
-
(2009)
Korean J Hepatol
, vol.15
, pp. 486-495
-
-
Shin, H.W.1
Park, S.Y.2
Lee, K.B.3
Shin, E.4
Nam, S.W.5
Lee, J.Y.6
-
268
-
-
38049086246
-
Canonical Wnt signaling maintains the quiescent stage of hepatic stellate cells
-
C. Kordes, I. Sawitza, and D. Haussinger Canonical Wnt signaling maintains the quiescent stage of hepatic stellate cells Biochem Biophys Res Commun 367 2008 116 123
-
(2008)
Biochem Biophys Res Commun
, vol.367
, pp. 116-123
-
-
Kordes, C.1
Sawitza, I.2
Haussinger, D.3
-
269
-
-
1042289785
-
Leptin stimulates tissue inhibitor of metalloproteinase-1 in human hepatic stellate cells: Respective roles of the JAK/STAT and JAK-mediated H2O2-dependant MAPK pathways
-
Q. Cao, K.M. Mak, C. Ren, and C.S. Lieber Leptin stimulates tissue inhibitor of metalloproteinase-1 in human hepatic stellate cells: respective roles of the JAK/STAT and JAK-mediated H2O2-dependant MAPK pathways J Biol Chem 279 2004 4292 4304
-
(2004)
J Biol Chem
, vol.279
, pp. 4292-4304
-
-
Cao, Q.1
Mak, K.M.2
Ren, C.3
Lieber, C.S.4
-
270
-
-
65749103808
-
Transcriptional regulation of hepatic stellate cells
-
J. Mann, and D.A. Mann Transcriptional regulation of hepatic stellate cells Adv Drug Deliv Rev 61 2009 497 512
-
(2009)
Adv Drug Deliv Rev
, vol.61
, pp. 497-512
-
-
Mann, J.1
Mann, D.A.2
-
271
-
-
75149141045
-
MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis
-
J. Mann, D.C. Chu, A. Maxwell, F. Oakley, N.L. Zhu, and H. Tsukamoto MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis Gastroenterology 138 2010 705 714 714.e14
-
(2010)
Gastroenterology
, vol.138
, pp. 705-714
-
-
Mann, J.1
Chu, D.C.2
Maxwell, A.3
Oakley, F.4
Zhu, N.L.5
Tsukamoto, H.6
-
273
-
-
61849096150
-
MiR-15b and miR-16 are implicated in activation of the rat hepatic stellate cell: An essential role for apoptosis
-
C.J. Guo, Q. Pan, D.G. Li, H. Sun, and B.W. Liu miR-15b and miR-16 are implicated in activation of the rat hepatic stellate cell: an essential role for apoptosis J Hepatol 50 2009 766 778
-
(2009)
J Hepatol
, vol.50
, pp. 766-778
-
-
Guo, C.J.1
Pan, Q.2
Li, D.G.3
Sun, H.4
Liu, B.W.5
-
274
-
-
70349783724
-
Effects of upregulated expression of microRNA-16 on biological properties of culture-activated hepatic stellate cells
-
C.J. Guo, Q. Pan, B. Jiang, G.Y. Chen, and D.G. Li Effects of upregulated expression of microRNA-16 on biological properties of culture-activated hepatic stellate cells Apoptosis 14 2009 1331 1340
-
(2009)
Apoptosis
, vol.14
, pp. 1331-1340
-
-
Guo, C.J.1
Pan, Q.2
Jiang, B.3
Chen, G.Y.4
Li, D.G.5
-
275
-
-
77951244487
-
MicroRNA: Antifibrogenic mediator in liver fibrogenesis
-
M. Kwiecinski, I. Strack, A. Noetel, S. Schivenbusch, N. Elfimova, and H.P. Dienes MicroRNA: antifibrogenic mediator in liver fibrogenesis J Hepatol 50 2009 S110
-
(2009)
J Hepatol
, vol.50
, pp. 110
-
-
Kwiecinski, M.1
Strack, I.2
Noetel, A.3
Schivenbusch, S.4
Elfimova, N.5
Dienes, H.P.6
-
276
-
-
38649114788
-
Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver
-
W.I. Jeong, D. Osei-Hyiaman, O. Park, J. Liu, S. Batkai, and P. Mukhopadhyay Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver Cell Metab 7 2008 227 235
-
(2008)
Cell Metab
, vol.7
, pp. 227-235
-
-
Jeong, W.I.1
Osei-Hyiaman, D.2
Park, O.3
Liu, J.4
Batkai, S.5
Mukhopadhyay, P.6
-
277
-
-
21344472982
-
Daily cannabis smoking as a risk factor for progression of fibrosis in chronic hepatitis C
-
C. Hezode, F. Roudot-Thoraval, S. Nguyen, P. Grenard, B. Julien, and E.S. Zafrani Daily cannabis smoking as a risk factor for progression of fibrosis in chronic hepatitis C Hepatology 42 2005 63 71
-
(2005)
Hepatology
, vol.42
, pp. 63-71
-
-
Hezode, C.1
Roudot-Thoraval, F.2
Nguyen, S.3
Grenard, P.4
Julien, B.5
Zafrani, E.S.6
-
278
-
-
38649131428
-
Daily cannabis use: A novel risk factor of steatosis severity in patients with chronic hepatitis C
-
C. Hezode, E.S. Zafrani, F. Roudot-Thoraval, C. Costentin, A. Hessami, and M. Bouvier-Alias Daily cannabis use: a novel risk factor of steatosis severity in patients with chronic hepatitis C Gastroenterology 134 2008 432 439
-
(2008)
Gastroenterology
, vol.134
, pp. 432-439
-
-
Hezode, C.1
Zafrani, E.S.2
Roudot-Thoraval, F.3
Costentin, C.4
Hessami, A.5
Bouvier-Alias, M.6
-
279
-
-
33745003240
-
CB1 cannabinoid receptor antagonism: A new strategy for the treatment of liver fibrosis
-
F. Teixeira-Clerc, B. Julien, P. Grenard, J. Tran Van Nhieu, V. Deveaux, and L. Li CB1 cannabinoid receptor antagonism: a new strategy for the treatment of liver fibrosis Nat Med 12 2006 671 676
-
(2006)
Nat Med
, vol.12
, pp. 671-676
-
-
Teixeira-Clerc, F.1
Julien, B.2
Grenard, P.3
Tran Van Nhieu, J.4
Deveaux, V.5
Li, L.6
-
280
-
-
42449136138
-
Long-term effect of CB1 blockade with rimonabant on cardiometabolic risk factors: Two year results from the RIO-Europe Study
-
L.F. Van Gaal, A.J. Scheen, A.M. Rissanen, S. Rossner, C. Hanotin, and O. Ziegler Long-term effect of CB1 blockade with rimonabant on cardiometabolic risk factors: two year results from the RIO-Europe Study Eur Heart J 29 2008 1761 1771
-
(2008)
Eur Heart J
, vol.29
, pp. 1761-1771
-
-
Van Gaal, L.F.1
Scheen, A.J.2
Rissanen, A.M.3
Rossner, S.4
Hanotin, C.5
Ziegler, O.6
-
281
-
-
38749134463
-
Regression of fibrosis after chronic stimulation of cannabinoid CB2 receptor in cirrhotic rats
-
J. Munoz-Luque, J. Ros, G. Fernandez-Varo, S. Tugues, M. Morales-Ruiz, and C.E. Alvarez Regression of fibrosis after chronic stimulation of cannabinoid CB2 receptor in cirrhotic rats J Pharmacol Exp Ther 324 2008 475 483
-
(2008)
J Pharmacol Exp Ther
, vol.324
, pp. 475-483
-
-
Munoz-Luque, J.1
Ros, J.2
Fernandez-Varo, G.3
Tugues, S.4
Morales-Ruiz, M.5
Alvarez, C.E.6
-
282
-
-
67649159879
-
Cannabinoid CB2 receptor potentiates obesity-associated inflammation, insulin resistance and hepatic steatosis
-
V. Deveaux, T. Cadoudal, Y. Ichigotani, F. Teixeira-Clerc, A. Louvet, and S. Manin Cannabinoid CB2 receptor potentiates obesity-associated inflammation, insulin resistance and hepatic steatosis PLoS ONE 4 2009 e5844
-
(2009)
PLoS ONE
, vol.4
, pp. 5844
-
-
Deveaux, V.1
Cadoudal, T.2
Ichigotani, Y.3
Teixeira-Clerc, F.4
Louvet, A.5
Manin, S.6
-
283
-
-
45849118669
-
Gene expression in human NAFLD
-
D. Greco, A. Kotronen, J. Westerbacka, O. Puig, P. Arkkila, and T. Kiviluoto Gene expression in human NAFLD Am J Physiol Gastrointest Liver Physiol 294 2008 G1281 G1287
-
(2008)
Am J Physiol Gastrointest Liver Physiol
, vol.294
-
-
Greco, D.1
Kotronen, A.2
Westerbacka, J.3
Puig, O.4
Arkkila, P.5
Kiviluoto, T.6
-
284
-
-
70349326750
-
Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity
-
E. Fabbrini, F. Magkos, B.S. Mohammed, T. Pietka, N.A. Abumrad, and B.W. Patterson Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity Proc Natl Acad Sci USA 106 2009 15430 15435
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 15430-15435
-
-
Fabbrini, E.1
Magkos, F.2
Mohammed, B.S.3
Pietka, T.4
Abumrad, N.A.5
Patterson, B.W.6
-
285
-
-
57649214103
-
Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD)
-
G. Musso, R. Gambino, and M. Cassader Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD) Prog Lipid Res 48 2009 1 26
-
(2009)
Prog Lipid Res
, vol.48
, pp. 1-26
-
-
Musso, G.1
Gambino, R.2
Cassader, M.3
-
286
-
-
0344874201
-
Contribution of hepatic de novo lipogenesis and reesterification of plasma non esterified fatty acids to plasma triglyceride synthesis during non-alcoholic fatty liver disease
-
F. Diraison, P. Moulin, and M. Beylot Contribution of hepatic de novo lipogenesis and reesterification of plasma non esterified fatty acids to plasma triglyceride synthesis during non-alcoholic fatty liver disease Diabetes Metab 29 2003 478 485
-
(2003)
Diabetes Metab
, vol.29
, pp. 478-485
-
-
Diraison, F.1
Moulin, P.2
Beylot, M.3
-
287
-
-
18244382304
-
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
-
K.L. Donnelly, C.I. Smith, S.J. Schwarzenberg, J. Jessurun, M.D. Boldt, and E.J. Parks Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease J Clin Invest 115 2005 1343 1351
-
(2005)
J Clin Invest
, vol.115
, pp. 1343-1351
-
-
Donnelly, K.L.1
Smith, C.I.2
Schwarzenberg, S.J.3
Jessurun, J.4
Boldt, M.D.5
Parks, E.J.6
-
288
-
-
29344441053
-
Apoptosis and Bcl-2 expression in the livers of patients with steatohepatitis
-
R.M. Ramalho, H. Cortez-Pinto, R.E. Castro, S. Sola, A. Costa, and M.C. Moura Apoptosis and Bcl-2 expression in the livers of patients with steatohepatitis Eur J Gastroenterol Hepatol 18 2006 21 29
-
(2006)
Eur J Gastroenterol Hepatol
, vol.18
, pp. 21-29
-
-
Ramalho, R.M.1
Cortez-Pinto, H.2
Castro, R.E.3
Sola, S.4
Costa, A.5
Moura, M.C.6
-
289
-
-
0042165989
-
Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis
-
A.E. Feldstein, A. Canbay, P. Angulo, M. Taniai, L.J. Burgart, and K.D. Lindor Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis Gastroenterology 125 2003 437 443
-
(2003)
Gastroenterology
, vol.125
, pp. 437-443
-
-
Feldstein, A.E.1
Canbay, A.2
Angulo, P.3
Taniai, M.4
Burgart, L.J.5
Lindor, K.D.6
-
290
-
-
33745095399
-
Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects
-
T.E. Graham, Q. Yang, M. Bluher, A. Hammarstedt, T.P. Ciaraldi, and R.R. Henry Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects N Engl J Med 354 2006 2552 2563
-
(2006)
N Engl J Med
, vol.354
, pp. 2552-2563
-
-
Graham, T.E.1
Yang, Q.2
Bluher, M.3
Hammarstedt, A.4
Ciaraldi, T.P.5
Henry, R.R.6
-
291
-
-
47149112739
-
Does retinol-binding protein 4 cause or reflect fatty liver disease?
-
M. Bluher, A. Tonjes, and M. Stumvoll Does retinol-binding protein 4 cause or reflect fatty liver disease? Hepatology 48 2008 4 6
-
(2008)
Hepatology
, vol.48
, pp. 4-6
-
-
Bluher, M.1
Tonjes, A.2
Stumvoll, M.3
-
292
-
-
38349135373
-
Serum retinol binding protein 4 and nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus
-
H. Wu, W. Jia, Y. Bao, J. Lu, J. Zhu, and R. Wang Serum retinol binding protein 4 and nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus Diabetes Res Clin Pract 79 2008 185 190
-
(2008)
Diabetes Res Clin Pract
, vol.79
, pp. 185-190
-
-
Wu, H.1
Jia, W.2
Bao, Y.3
Lu, J.4
Zhu, J.5
Wang, R.6
-
293
-
-
67349205002
-
Kupffer cells in non-alcoholic fatty liver disease: The emerging view
-
G. Baffy Kupffer cells in non-alcoholic fatty liver disease: the emerging view J Hepatol 51 2009 212 223
-
(2009)
J Hepatol
, vol.51
, pp. 212-223
-
-
Baffy, G.1
-
294
-
-
0033767987
-
Characterization of pathogenic and prognostic factors of nonalcoholic steatohepatitis associated with obesity
-
C. Garcia-Monzon, E. Martin-Perez, O.L. Iacono, M. Fernandez-Bermejo, P.L. Majano, and A. Apolinario Characterization of pathogenic and prognostic factors of nonalcoholic steatohepatitis associated with obesity J Hepatol 33 2000 716 724
-
(2000)
J Hepatol
, vol.33
, pp. 716-724
-
-
Garcia-Monzon, C.1
Martin-Perez, E.2
Iacono, O.L.3
Fernandez-Bermejo, M.4
Majano, P.L.5
Apolinario, A.6
-
295
-
-
77649337140
-
Nonalcoholic fatty liver disease: Pathology and pathogenesis
-
D.G. Tiniakos, M.B. Vos, and E.M. Brunt Nonalcoholic fatty liver disease: pathology and pathogenesis Annu Rev Pathol 5 2010 145 171
-
(2010)
Annu Rev Pathol
, vol.5
, pp. 145-171
-
-
Tiniakos, D.G.1
Vos, M.B.2
Brunt, E.M.3
-
296
-
-
77949311823
-
Nonalcoholic fatty liver disease: A review and update
-
J.R. Lewis, and S.R. Mohanty Nonalcoholic fatty liver disease: a review and update Dig Dis Sci 55 2010 560 578
-
(2010)
Dig Dis Sci
, vol.55
, pp. 560-578
-
-
Lewis, J.R.1
Mohanty, S.R.2
-
298
-
-
33846985915
-
Immunopathogenesis in hepatitis C virus cirrhosis
-
U. Spengler, and J. Nattermann Immunopathogenesis in hepatitis C virus cirrhosis Clin Sci (Lond) 112 2007 141 155
-
(2007)
Clin Sci (Lond)
, vol.112
, pp. 141-155
-
-
Spengler, U.1
Nattermann, J.2
-
300
-
-
33644830723
-
+ T cells is enhanced by co-culture with hepatocytes expressing hepatitis C virus (HCV) structural proteins through FasL induction
-
+ T cells is enhanced by co-culture with hepatocytes expressing hepatitis C virus (HCV) structural proteins through FasL induction Virology 346 2006 363 372
-
(2006)
Virology
, vol.346
, pp. 363-372
-
-
Iken, K.1
Huang, L.2
Bekele, H.3
Schmidt, E.V.4
Koziel, M.J.5
-
301
-
-
0842300376
-
Hepatitis C virus core and nonstructural proteins induce fibrogenic effects in hepatic stellate cells
-
R. Bataller, Y.H. Paik, J.N. Lindquist, J.J. Lemasters, and D.A. Brenner Hepatitis C virus core and nonstructural proteins induce fibrogenic effects in hepatic stellate cells Gastroenterology 126 2004 529 540
-
(2004)
Gastroenterology
, vol.126
, pp. 529-540
-
-
Bataller, R.1
Paik, Y.H.2
Lindquist, J.N.3
Lemasters, J.J.4
Brenner, D.A.5
-
303
-
-
15744403731
-
Binding of hepatitis C virus envelope protein E2 to CD81 up-regulates matrix metalloproteinase-2 in human hepatic stellate cells
-
A. Mazzocca, S.C. Sciammetta, V. Carloni, L. Cosmi, F. Annunziato, and T. Harada Binding of hepatitis C virus envelope protein E2 to CD81 up-regulates matrix metalloproteinase-2 in human hepatic stellate cells J Biol Chem 280 2005 11329 11339
-
(2005)
J Biol Chem
, vol.280
, pp. 11329-11339
-
-
Mazzocca, A.1
Sciammetta, S.C.2
Carloni, V.3
Cosmi, L.4
Annunziato, F.5
Harada, T.6
-
304
-
-
0030947554
-
The tetraspanin superfamily: Molecular facilitators
-
H.T. Maecker, S.C. Todd, and S. Levy The tetraspanin superfamily: molecular facilitators FASEB J 11 1997 428 442
-
(1997)
FASEB J
, vol.11
, pp. 428-442
-
-
Maecker, H.T.1
Todd, S.C.2
Levy, S.3
-
305
-
-
17944385968
-
Structurefunction analysis of hepatitis C virus envelope-CD81 binding
-
R. Petracca, F. Falugi, G. Galli, N. Norais, D. Rosa, and S. Campagnoli Structurefunction analysis of hepatitis C virus envelope-CD81 binding J Virol 74 2000 4824 4830
-
(2000)
J Virol
, vol.74
, pp. 4824-4830
-
-
Petracca, R.1
Falugi, F.2
Galli, G.3
Norais, N.4
Rosa, D.5
Campagnoli, S.6
-
306
-
-
0032582538
-
Binding of hepatitis C virus to CD81
-
P. Pileri, Y. Uematsu, S. Campagnoli, G. Galli, F. Falugi, and R. Petracca Binding of hepatitis C virus to CD81 Science 282 1998 938 941
-
(1998)
Science
, vol.282
, pp. 938-941
-
-
Pileri, P.1
Uematsu, Y.2
Campagnoli, S.3
Galli, G.4
Falugi, F.5
Petracca, R.6
-
307
-
-
33646529840
-
Relationship between steatosis, inflammation, and fibrosis in chronic hepatitis C: A meta-analysis of individual patient data
-
G. Leandro, A. Mangia, J. Hui, P. Fabris, L. Rubbia-Brandt, and G. Colloredo Relationship between steatosis, inflammation, and fibrosis in chronic hepatitis C: a meta-analysis of individual patient data Gastroenterology 130 2006 1636 1642
-
(2006)
Gastroenterology
, vol.130
, pp. 1636-1642
-
-
Leandro, G.1
Mangia, A.2
Hui, J.3
Fabris, P.4
Rubbia-Brandt, L.5
Colloredo, G.6
-
308
-
-
0031055840
-
Analysis of histopathological manifestations of chronic hepatitis C virus infection with respect to virus genotype
-
S. Mihm, A. Fayyazi, H. Hartmann, and G. Ramadori Analysis of histopathological manifestations of chronic hepatitis C virus infection with respect to virus genotype Hepatology 25 1997 735 739
-
(1997)
Hepatology
, vol.25
, pp. 735-739
-
-
Mihm, S.1
Fayyazi, A.2
Hartmann, H.3
Ramadori, G.4
-
309
-
-
10744224920
-
Steatosis affects chronic hepatitis C progression in a genotype specific way
-
L. Rubbia-Brandt, P. Fabris, S. Paganin, G. Leandro, P.J. Male, and E. Giostra Steatosis affects chronic hepatitis C progression in a genotype specific way Gut 53 2004 406 412
-
(2004)
Gut
, vol.53
, pp. 406-412
-
-
Rubbia-Brandt, L.1
Fabris, P.2
Paganin, S.3
Leandro, G.4
Male, P.J.5
Giostra, E.6
-
310
-
-
0038122773
-
Effect of treatment with peginterferon or interferon alfa-2b and ribavirin on steatosis in patients infected with hepatitis C
-
T. Poynard, V. Ratziu, J. McHutchison, M. Manns, Z. Goodman, and S. Zeuzem Effect of treatment with peginterferon or interferon alfa-2b and ribavirin on steatosis in patients infected with hepatitis C Hepatology 38 2003 75 85
-
(2003)
Hepatology
, vol.38
, pp. 75-85
-
-
Poynard, T.1
Ratziu, V.2
McHutchison, J.3
Manns, M.4
Goodman, Z.5
Zeuzem, S.6
-
311
-
-
29244484291
-
Steatosis in chronic hepatitis C: Why does it really matter?
-
T. Asselah, L. Rubbia-Brandt, P. Marcellin, and F. Negro Steatosis in chronic hepatitis C: why does it really matter? Gut 55 2006 123 130
-
(2006)
Gut
, vol.55
, pp. 123-130
-
-
Asselah, T.1
Rubbia-Brandt, L.2
Marcellin, P.3
Negro, F.4
-
312
-
-
10744220759
-
Liver fibrosis is not associated with steatosis but with necroinflammation in French patients with chronic hepatitis C
-
T. Asselah, N. Boyer, M.C. Guimont, D. Cazals-Hatem, F. Tubach, and K. Nahon Liver fibrosis is not associated with steatosis but with necroinflammation in French patients with chronic hepatitis C Gut 52 2003 1638 1643
-
(2003)
Gut
, vol.52
, pp. 1638-1643
-
-
Asselah, T.1
Boyer, N.2
Guimont, M.C.3
Cazals-Hatem, D.4
Tubach, F.5
Nahon, K.6
-
313
-
-
34347205995
-
Hepatitis C and steatosis
-
E. Bjornsson, and P. Angulo Hepatitis C and steatosis Arch Med Res 38 2007 621 627
-
(2007)
Arch Med Res
, vol.38
, pp. 621-627
-
-
Bjornsson, E.1
Angulo, P.2
-
314
-
-
0036060095
-
Hepatitis C virus NS5A colocalizes with the core protein on lipid droplets and interacts with apolipoproteins
-
S.T. Shi, S.J. Polyak, H. Tu, D.R. Taylor, D.R. Gretch, and M.M. Lai Hepatitis C virus NS5A colocalizes with the core protein on lipid droplets and interacts with apolipoproteins Virology 292 2002 198 210
-
(2002)
Virology
, vol.292
, pp. 198-210
-
-
Shi, S.T.1
Polyak, S.J.2
Tu, H.3
Taylor, D.R.4
Gretch, D.R.5
Lai, M.M.6
-
315
-
-
11144357274
-
Hepatitis C virus core protein shows a cytoplasmic localization and associates to cellular lipid storage droplets
-
G. Barba, F. Harper, T. Harada, M. Kohara, S. Goulinet, and Y. Matsuura Hepatitis C virus core protein shows a cytoplasmic localization and associates to cellular lipid storage droplets Proc Natl Acad Sci USA 94 1997 1200 1205
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 1200-1205
-
-
Barba, G.1
Harper, F.2
Harada, T.3
Kohara, M.4
Goulinet, S.5
Matsuura, Y.6
-
316
-
-
18244365866
-
Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: A model of viral-related steatosis
-
G. Perlemuter, A. Sabile, P. Letteron, G. Vona, A. Topilco, and Y. Chretien Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: a model of viral-related steatosis FASEB J 16 2002 185 194
-
(2002)
FASEB J
, vol.16
, pp. 185-194
-
-
Perlemuter, G.1
Sabile, A.2
Letteron, P.3
Vona, G.4
Topilco, A.5
Chretien, Y.6
-
317
-
-
34548788465
-
Proteomic profiling of human liver biopsies: Hepatitis C virus-induced fibrosis and mitochondrial dysfunction
-
D.L. Diamond, J.M. Jacobs, B. Paeper, S.C. Proll, M.A. Gritsenko, and R.L.J. Carithers Proteomic profiling of human liver biopsies: hepatitis C virus-induced fibrosis and mitochondrial dysfunction Hepatology 46 2007 649 657
-
(2007)
Hepatology
, vol.46
, pp. 649-657
-
-
Diamond, D.L.1
Jacobs, J.M.2
Paeper, B.3
Proll, S.C.4
Gritsenko, M.A.5
Carithers, R.L.J.6
-
318
-
-
54549102155
-
Disease-specific mechanisms of fibrosis: Hepatitis C virus and nonalcoholic steatohepatitis
-
D. van der Poorten, and J. George Disease-specific mechanisms of fibrosis: hepatitis C virus and nonalcoholic steatohepatitis Clin Liver Dis 12 2008 805 824 ix
-
(2008)
Clin Liver Dis
, vol.12
, pp. 805-824
-
-
Van Der Poorten, D.1
George, J.2
-
319
-
-
23044477984
-
Complement factor 5 is a quantitative trait gene that modifies liver fibrogenesis in mice and humans
-
S. Hillebrandt, H.E. Wasmuth, R. Weiskirchen, C. Hellerbrand, H. Keppeler, and A. Werth Complement factor 5 is a quantitative trait gene that modifies liver fibrogenesis in mice and humans Nat Genet 37 2005 835 843
-
(2005)
Nat Genet
, vol.37
, pp. 835-843
-
-
Hillebrandt, S.1
Wasmuth, H.E.2
Weiskirchen, R.3
Hellerbrand, C.4
Keppeler, H.5
Werth, A.6
-
321
-
-
54949138100
-
Genetic determinants in hepatic fibrosis: From experimental models to fibrogenic gene signatures in humans
-
S. Weber, O.A. Gressner, R. Hall, F. Grunhage, and F. Lammert Genetic determinants in hepatic fibrosis: from experimental models to fibrogenic gene signatures in humans Clin Liver Dis 12 2008 747 757 vii
-
(2008)
Clin Liver Dis
, vol.12
, pp. 747-757
-
-
Weber, S.1
Gressner, O.A.2
Hall, R.3
Grunhage, F.4
Lammert, F.5
-
322
-
-
3042550624
-
Upregulation of osteopontin expression is involved in the development of nonalcoholic steatohepatitis in a dietary murine model
-
A. Sahai, P. Malladi, H. Melin-Aldana, R.M. Green, and P.F. Whitington Upregulation of osteopontin expression is involved in the development of nonalcoholic steatohepatitis in a dietary murine model Am J Physiol Gastrointest Liver Physiol 287 2004 G264 G273
-
(2004)
Am J Physiol Gastrointest Liver Physiol
, vol.287
-
-
Sahai, A.1
Malladi, P.2
Melin-Aldana, H.3
Green, R.M.4
Whitington, P.F.5
-
323
-
-
3042592451
-
SOCS1 is a suppressor of liver fibrosis and hepatitis-induced carcinogenesis
-
T. Yoshida, H. Ogata, M. Kamio, A. Joo, H. Shiraishi, and Y. Tokunaga SOCS1 is a suppressor of liver fibrosis and hepatitis-induced carcinogenesis J Exp Med 199 2004 1701 1707
-
(2004)
J Exp Med
, vol.199
, pp. 1701-1707
-
-
Yoshida, T.1
Ogata, H.2
Kamio, M.3
Joo, A.4
Shiraishi, H.5
Tokunaga, Y.6
-
324
-
-
0037784230
-
Interleukin 6/gp 130-dependent pathways are protective during chronic liver diseases
-
K.L. Streetz, F. Tacke, L. Leifeld, T. Wustefeld, A. Graw, and C. Klein Interleukin 6/gp 130-dependent pathways are protective during chronic liver diseases Hepatology 38 2003 218 229
-
(2003)
Hepatology
, vol.38
, pp. 218-229
-
-
Streetz, K.L.1
Tacke, F.2
Leifeld, L.3
Wustefeld, T.4
Graw, A.5
Klein, C.6
-
325
-
-
77949319204
-
A DDX5 S480A polymorphism is associated with increased transcription of fibrogenic genes in hepatic stellate cells
-
J. Guo, F. Hong, J. Loke, S. Yea, C.L. Lim, and U. Lee A DDX5 S480A polymorphism is associated with increased transcription of fibrogenic genes in hepatic stellate cells J Biol Chem 285 2010 5428 5437
-
(2010)
J Biol Chem
, vol.285
, pp. 5428-5437
-
-
Guo, J.1
Hong, F.2
Loke, J.3
Yea, S.4
Lim, C.L.5
Lee, U.6
-
326
-
-
0038374866
-
Conditional tetracycline-regulated expression of TGF-beta1 in liver of transgenic mice leads to reversible intermediary fibrosis
-
E. Ueberham, R. Low, U. Ueberham, K. Schonig, H. Bujard, and R. Gebhardt Conditional tetracycline-regulated expression of TGF-beta1 in liver of transgenic mice leads to reversible intermediary fibrosis Hepatology 37 2003 1067 1078
-
(2003)
Hepatology
, vol.37
, pp. 1067-1078
-
-
Ueberham, E.1
Low, R.2
Ueberham, U.3
Schonig, K.4
Bujard, H.5
Gebhardt, R.6
-
327
-
-
70350075399
-
A novel nonsynonymous variant of matrix metalloproteinase-7 confers risk of liver cirrhosis
-
T.M. Hung, S.C. Chang, W.H. Yu, Y.W. Wang, C. Huang, and S.C. Lu A novel nonsynonymous variant of matrix metalloproteinase-7 confers risk of liver cirrhosis Hepatology 50 2009 1184 1193
-
(2009)
Hepatology
, vol.50
, pp. 1184-1193
-
-
Hung, T.M.1
Chang, S.C.2
Yu, W.H.3
Wang, Y.W.4
Huang, C.5
Lu, S.C.6
-
328
-
-
0344796403
-
Association of genetic variants of the chemokine receptor CCR5 and its ligands, RANTES and MCP-2, with outcome of HCV infection
-
S. Hellier, A.J. Frodsham, B.J. Hennig, P. Klenerman, S. Knapp, and P. Ramaley Association of genetic variants of the chemokine receptor CCR5 and its ligands, RANTES and MCP-2, with outcome of HCV infection Hepatology 38 2003 1468 1476
-
(2003)
Hepatology
, vol.38
, pp. 1468-1476
-
-
Hellier, S.1
Frodsham, A.J.2
Hennig, B.J.3
Klenerman, P.4
Knapp, S.5
Ramaley, P.6
-
329
-
-
17144459376
-
A novel MCP-1 gene polymorphism is associated with hepatic MCP-1 expression and severity of HCV-related liver disease
-
M. Muhlbauer, A.K. Bosserhoff, A. Hartmann, W.E. Thasler, T.S. Weiss, and H. Herfarth A novel MCP-1 gene polymorphism is associated with hepatic MCP-1 expression and severity of HCV-related liver disease Gastroenterology 125 2003 1085 1093
-
(2003)
Gastroenterology
, vol.125
, pp. 1085-1093
-
-
Muhlbauer, M.1
Bosserhoff, A.K.2
Hartmann, A.3
Thasler, W.E.4
Weiss, T.S.5
Herfarth, H.6
-
330
-
-
34548301514
-
A 7 gene signature identifies the risk of developing cirrhosis in patients with chronic hepatitis C
-
H. Huang, M.L. Shiffman, S. Friedman, R. Venkatesh, N. Bzowej, and O.T. Abar A 7 gene signature identifies the risk of developing cirrhosis in patients with chronic hepatitis C Hepatology 46 2007 297 306
-
(2007)
Hepatology
, vol.46
, pp. 297-306
-
-
Huang, H.1
Shiffman, M.L.2
Friedman, S.3
Venkatesh, R.4
Bzowej, N.5
Abar, O.T.6
-
331
-
-
70350054801
-
A seven-gene signature (cirrhosis risk score) predicts liver fibrosis progression in patients with initially mild chronic hepatitis C
-
M. Marcolongo, B. Young, F. Dal Pero, G. Fattovich, L. Peraro, and M. Guido A seven-gene signature (cirrhosis risk score) predicts liver fibrosis progression in patients with initially mild chronic hepatitis C Hepatology 50 2009 1038 1044
-
(2009)
Hepatology
, vol.50
, pp. 1038-1044
-
-
Marcolongo, M.1
Young, B.2
Dal Pero, F.3
Fattovich, G.4
Peraro, L.5
Guido, M.6
-
332
-
-
0034799113
-
Ninety patients with nonalcoholic steatohepatitis: Insulin resistance, familial tendency, and severity of disease
-
I.R. Willner, B. Waters, S.R. Patil, A. Reuben, J. Morelli, and C.A. Riely Ninety patients with nonalcoholic steatohepatitis: insulin resistance, familial tendency, and severity of disease Am J Gastroenterol 96 2001 2957 2961
-
(2001)
Am J Gastroenterol
, vol.96
, pp. 2957-2961
-
-
Willner, I.R.1
Waters, B.2
Patil, S.R.3
Reuben, A.4
Morelli, J.5
Riely, C.A.6
-
333
-
-
0343314903
-
Nonalcoholic steatohepatitis and cryptogenic cirrhosis within kindreds
-
V.M. Struben, E.E. Hespenheide, and S.H. Caldwell Nonalcoholic steatohepatitis and cryptogenic cirrhosis within kindreds Am J Med 108 2000 9 13
-
(2000)
Am J Med
, vol.108
, pp. 9-13
-
-
Struben, V.M.1
Hespenheide, E.E.2
Caldwell, S.H.3
-
334
-
-
33847008303
-
Genetics of alcoholic liver disease and nonalcoholic fatty liver disease
-
N.M. Wilfred de Alwis, and C.P. Day Genetics of alcoholic liver disease and nonalcoholic fatty liver disease Semin Liver Dis 27 2007 44 54
-
(2007)
Semin Liver Dis
, vol.27
, pp. 44-54
-
-
Wilfred De Alwis, N.M.1
Day, C.P.2
-
335
-
-
56749096610
-
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
-
S. Romeo, J. Kozlitina, C. Xing, A. Pertsemlidis, D. Cox, and L.A. Pennacchio Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease Nat Genet 40 2008 1461 1465
-
(2008)
Nat Genet
, vol.40
, pp. 1461-1465
-
-
Romeo, S.1
Kozlitina, J.2
Xing, C.3
Pertsemlidis, A.4
Cox, D.5
Pennacchio, L.A.6
-
336
-
-
73349111259
-
Variant in PNPLA3 is associated with alcoholic liver disease
-
C. Tian, R.P. Stokowski, D. Kershenobich, D.G. Ballinger, and D.A. Hinds Variant in PNPLA3 is associated with alcoholic liver disease Nat Genet 42 2010 21 23
-
(2010)
Nat Genet
, vol.42
, pp. 21-23
-
-
Tian, C.1
Stokowski, R.P.2
Kershenobich, D.3
Ballinger, D.G.4
Hinds, D.A.5
-
337
-
-
46049097550
-
The Kruppel-like factor 6 genotype is associated with fibrosis in nonalcoholic fatty liver disease
-
L. Miele, G. Beale, G. Patman, V. Nobili, J. Leathart, and A. Grieco The Kruppel-like factor 6 genotype is associated with fibrosis in nonalcoholic fatty liver disease Gastroenterology 135 2008 282 291 e1
-
(2008)
Gastroenterology
, vol.135
, pp. 282-291
-
-
Miele, L.1
Beale, G.2
Patman, G.3
Nobili, V.4
Leathart, J.5
Grieco, A.6
-
338
-
-
56649083495
-
Mechanisms of disease progression in nonalcoholic fatty liver disease
-
J. Jou, S.S. Choi, and A.M. Diehl Mechanisms of disease progression in nonalcoholic fatty liver disease Semin Liver Dis 28 2008 370 379
-
(2008)
Semin Liver Dis
, vol.28
, pp. 370-379
-
-
Jou, J.1
Choi, S.S.2
Diehl, A.M.3
-
339
-
-
33646202790
-
The role of genetic polymorphisms in alcoholic liver disease
-
F. Stickel, and C.H. Osterreicher The role of genetic polymorphisms in alcoholic liver disease Alcohol Alcohol 41 2006 209 224
-
(2006)
Alcohol Alcohol
, vol.41
, pp. 209-224
-
-
Stickel, F.1
Osterreicher, C.H.2
-
340
-
-
0035188749
-
Genetic polymorphisms of alcohol metabolizing enzymes
-
D.P. Agarwal Genetic polymorphisms of alcohol metabolizing enzymes Pathol Biol (Paris) 49 2001 703 709
-
(2001)
Pathol Biol (Paris)
, vol.49
, pp. 703-709
-
-
Agarwal, D.P.1
-
341
-
-
4143103585
-
Primary biliary cirrhosis in monozygotic and dizygotic twins: Genetics, epigenetics, and environment
-
C. Selmi, M.J. Mayo, N. Bach, H. Ishibashi, P. Invernizzi, and R.G. Gish Primary biliary cirrhosis in monozygotic and dizygotic twins: genetics, epigenetics, and environment Gastroenterology 127 2004 485 492
-
(2004)
Gastroenterology
, vol.127
, pp. 485-492
-
-
Selmi, C.1
Mayo, M.J.2
Bach, N.3
Ishibashi, H.4
Invernizzi, P.5
Gish, R.G.6
-
342
-
-
0032587434
-
Familial primary biliary cirrhosis reassessed: A geographically-based population study
-
D.E. Jones, F.E. Watt, J.V. Metcalf, M.F. Bassendine, and O.F. James Familial primary biliary cirrhosis reassessed: a geographically-based population study J Hepatol 30 1999 402 407
-
(1999)
J Hepatol
, vol.30
, pp. 402-407
-
-
Jones, D.E.1
Watt, F.E.2
Metcalf, J.V.3
Bassendine, M.F.4
James, O.F.5
-
343
-
-
67149095289
-
Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants
-
G.M. Hirschfield, X. Liu, C. Xu, Y. Lu, G. Xie, and Y. Lu Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants N Engl J Med 360 2009 2544 2555
-
(2009)
N Engl J Med
, vol.360
, pp. 2544-2555
-
-
Hirschfield, G.M.1
Liu, X.2
Xu, C.3
Lu, Y.4
Xie, G.5
Lu, Y.6
-
344
-
-
37549058451
-
How microorganisms tip the balance between interleukin-12 family members
-
S. Goriely, M.F. Neurath, and M. Goldman How microorganisms tip the balance between interleukin-12 family members Nat Rev Immunol 8 2008 81 86
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 81-86
-
-
Goriely, S.1
Neurath, M.F.2
Goldman, M.3
-
345
-
-
0035061020
-
HLA and interleukin 1 gene polymorphisms in primary biliary cirrhosis: Associations with disease progression and disease susceptibility
-
P. Donaldson, K. Agarwal, A. Craggs, W. Craig, O. James, and D. Jones HLA and interleukin 1 gene polymorphisms in primary biliary cirrhosis: associations with disease progression and disease susceptibility Gut 48 2001 397 402
-
(2001)
Gut
, vol.48
, pp. 397-402
-
-
Donaldson, P.1
Agarwal, K.2
Craggs, A.3
Craig, W.4
James, O.5
Jones, D.6
-
346
-
-
77249164222
-
Genome-wide association analysis in primary sclerosing cholangitis
-
T.H. Karlsen, A. Franke, E. Melum, A. Kaser, J.R. Hov, and T. Balschun Genome-wide association analysis in primary sclerosing cholangitis Gastroenterology 138 2010 1102 1111
-
(2010)
Gastroenterology
, vol.138
, pp. 1102-1111
-
-
Karlsen, T.H.1
Franke, A.2
Melum, E.3
Kaser, A.4
Hov, J.R.5
Balschun, T.6
-
347
-
-
55749109703
-
Interferon-based therapy for chronic hepatitis C: Current and future perspectives
-
S. Zeuzem Interferon-based therapy for chronic hepatitis C: current and future perspectives Nat Clin Pract Gastroenterol Hepatol 5 2008 610 622
-
(2008)
Nat Clin Pract Gastroenterol Hepatol
, vol.5
, pp. 610-622
-
-
Zeuzem, S.1
-
348
-
-
70349533037
-
Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C
-
Y. Tanaka, N. Nishida, M. Sugiyama, M. Kurosaki, K. Matsuura, and N. Sakamoto Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C Nat Genet 41 2009 1105 1109
-
(2009)
Nat Genet
, vol.41
, pp. 1105-1109
-
-
Tanaka, Y.1
Nishida, N.2
Sugiyama, M.3
Kurosaki, M.4
Matsuura, K.5
Sakamoto, N.6
-
349
-
-
70349548852
-
IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy
-
V. Suppiah, M. Moldovan, G. Ahlenstiel, T. Berg, M. Weltman, and M.L. Abate IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy Nat Genet 41 2009 1100 1104
-
(2009)
Nat Genet
, vol.41
, pp. 1100-1104
-
-
Suppiah, V.1
Moldovan, M.2
Ahlenstiel, G.3
Berg, T.4
Weltman, M.5
Abate, M.L.6
-
350
-
-
70349292099
-
Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
-
D. Ge, J. Fellay, A.J. Thompson, J.S. Simon, K.V. Shianna, and T.J. Urban Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance Nature 461 2009 399 401
-
(2009)
Nature
, vol.461
, pp. 399-401
-
-
Ge, D.1
Fellay, J.2
Thompson, A.J.3
Simon, J.S.4
Shianna, K.V.5
Urban, T.J.6
-
351
-
-
70349966196
-
Genetic variation in IL28B and spontaneous clearance of hepatitis C virus
-
D.L. Thomas, C.L. Thio, M.P. Martin, Y. Qi, D. Ge, and C. O'Huigin Genetic variation in IL28B and spontaneous clearance of hepatitis C virus Nature 461 2009 798 801
-
(2009)
Nature
, vol.461
, pp. 798-801
-
-
Thomas, D.L.1
Thio, C.L.2
Martin, M.P.3
Qi, Y.4
Ge, D.5
O'Huigin, C.6
-
353
-
-
0033369104
-
Are haemochromatosis mutations related to the severity of liver disease in hepatitis C virus infection?
-
A.L. Martinelli, R.F. Franco, M.G. Villanova, J.F. Figueiredo, M. Secaf, and M.H. Tavella Are haemochromatosis mutations related to the severity of liver disease in hepatitis C virus infection? Acta Haematol 102 2000 152 156
-
(2000)
Acta Haematol
, vol.102
, pp. 152-156
-
-
Martinelli, A.L.1
Franco, R.F.2
Villanova, M.G.3
Figueiredo, J.F.4
Secaf, M.5
Tavella, M.H.6
-
354
-
-
0019813866
-
Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis
-
R.G. Knodell, K.G. Ishak, W.C. Black, T.S. Chen, R. Craig, and N. Kaplowitz Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis Hepatology 1 1981 431 435
-
(1981)
Hepatology
, vol.1
, pp. 431-435
-
-
Knodell, R.G.1
Ishak, K.G.2
Black, W.C.3
Chen, T.S.4
Craig, R.5
Kaplowitz, N.6
-
355
-
-
0030933395
-
Natural history of liver fibrosis progression in patients with chronic hepatitis C. The OBSVIRC, METAVIR, CLINIVIR, and DOSVIRC groups
-
T. Poynard, P. Bedossa, and P. Opolon Natural history of liver fibrosis progression in patients with chronic hepatitis C. The OBSVIRC, METAVIR, CLINIVIR, and DOSVIRC groups Lancet 349 1997 825 832
-
(1997)
Lancet
, vol.349
, pp. 825-832
-
-
Poynard, T.1
Bedossa, P.2
Opolon, P.3
-
356
-
-
0028235641
-
Classification of chronic hepatitis: Diagnosis, grading and staging
-
V.J. Desmet, M. Gerber, J.H. Hoofnagle, M. Manns, and P.J. Scheuer Classification of chronic hepatitis: diagnosis, grading and staging Hepatology 19 1994 1513 1520
-
(1994)
Hepatology
, vol.19
, pp. 1513-1520
-
-
Desmet, V.J.1
Gerber, M.2
Hoofnagle, J.H.3
Manns, M.4
Scheuer, P.J.5
-
357
-
-
34247149014
-
Scar-associated macrophages are a major source of hepatic matrix metalloproteinase-13 and facilitate the resolution of murine hepatic fibrosis
-
J.A. Fallowfield, M. Mizuno, T.J. Kendall, C.M. Constandinou, R.C. Benyon, and J.S. Duffield Scar-associated macrophages are a major source of hepatic matrix metalloproteinase-13 and facilitate the resolution of murine hepatic fibrosis J Immunol 178 2007 5288 5295
-
(2007)
J Immunol
, vol.178
, pp. 5288-5295
-
-
Fallowfield, J.A.1
Mizuno, M.2
Kendall, T.J.3
Constandinou, C.M.4
Benyon, R.C.5
Duffield, J.S.6
-
358
-
-
0032146551
-
Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors
-
J.P. Iredale, R.C. Benyon, J. Pickering, M. McCullen, M. Northrop, and S. Pawley Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors J Clin Invest 102 1998 538 549
-
(1998)
J Clin Invest
, vol.102
, pp. 538-549
-
-
Iredale, J.P.1
Benyon, R.C.2
Pickering, J.3
McCullen, M.4
Northrop, M.5
Pawley, S.6
-
359
-
-
0035083958
-
Apoptosis of hepatic stellate cells: Involvement in resolution of biliary fibrosis and regulation by soluble growth factors
-
R. Issa, E. Williams, N. Trim, T. Kendall, M.J. Arthur, and J. Reichen Apoptosis of hepatic stellate cells: involvement in resolution of biliary fibrosis and regulation by soluble growth factors Gut 48 2001 548 557
-
(2001)
Gut
, vol.48
, pp. 548-557
-
-
Issa, R.1
Williams, E.2
Trim, N.3
Kendall, T.4
Arthur, M.J.5
Reichen, J.6
-
360
-
-
59149102918
-
Inverse association between hepatic stellate cell apoptosis and fibrosis in chronic hepatitis C virus infection
-
S.A. Gonzalez, M.I. Fiel, J. Sauk, P.W. Canchis, R.C. Liu, and L. Chiriboga Inverse association between hepatic stellate cell apoptosis and fibrosis in chronic hepatitis C virus infection J Viral Hepat 16 2009 141 148
-
(2009)
J Viral Hepat
, vol.16
, pp. 141-148
-
-
Gonzalez, S.A.1
Fiel, M.I.2
Sauk, J.3
Canchis, P.W.4
Liu, R.C.5
Chiriboga, L.6
-
361
-
-
33746120376
-
Overexpression of Bcl-2 by activated human hepatic stellate cells: Resistance to apoptosis as a mechanism of progressive hepatic fibrogenesis in humans
-
E. Novo, F. Marra, E. Zamara, L. Valfre di Bonzo, L. Monitillo, and S. Cannito Overexpression of Bcl-2 by activated human hepatic stellate cells: resistance to apoptosis as a mechanism of progressive hepatic fibrogenesis in humans Gut 55 2006 1174 1182
-
(2006)
Gut
, vol.55
, pp. 1174-1182
-
-
Novo, E.1
Marra, F.2
Zamara, E.3
Valfre Di Bonzo, L.4
Monitillo, L.5
Cannito, S.6
-
362
-
-
63349106442
-
P75 Neurotrophin receptor signaling regulates hepatic myofibroblast proliferation and apoptosis in recovery from rodent liver fibrosis
-
T.J. Kendall, S. Hennedige, R.L. Aucott, S.N. Hartland, M.A. Vernon, and R.C. Benyon p75 Neurotrophin receptor signaling regulates hepatic myofibroblast proliferation and apoptosis in recovery from rodent liver fibrosis Hepatology 49 2009 901 910
-
(2009)
Hepatology
, vol.49
, pp. 901-910
-
-
Kendall, T.J.1
Hennedige, S.2
Aucott, R.L.3
Hartland, S.N.4
Vernon, M.A.5
Benyon, R.C.6
-
363
-
-
66149104271
-
Angiotensin II activates i kappaB kinase phosphorylation of RelA at ser 536 to promote myofibroblast survival and liver fibrosis
-
F. Oakley, V. Teoh, G. Ching-A-Sue, R. Bataller, J. Colmenero, and J.R. Jonsson Angiotensin II activates I kappaB kinase phosphorylation of RelA at Ser 536 to promote myofibroblast survival and liver fibrosis Gastroenterology 136 2009 2334 2344 e1
-
(2009)
Gastroenterology
, vol.136
, pp. 2334-2344
-
-
Oakley, F.1
Teoh, V.2
Ching-A-Sue, G.3
Bataller, R.4
Colmenero, J.5
Jonsson, J.R.6
-
364
-
-
11144325650
-
Inhibition of inhibitor of kappaB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis
-
F. Oakley, M. Meso, J.P. Iredale, K. Green, C.J. Marek, and X. Zhou Inhibition of inhibitor of kappaB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis Gastroenterology 128 2005 108 120
-
(2005)
Gastroenterology
, vol.128
, pp. 108-120
-
-
Oakley, F.1
Meso, M.2
Iredale, J.P.3
Green, K.4
Marek, C.J.5
Zhou, X.6
-
365
-
-
67349172516
-
Apoptotic body engulfment by hepatic stellate cells promotes their survival by the JAK/STAT and Akt/NF-kappaB-dependent pathways
-
J.X. Jiang, K. Mikami, S. Venugopal, Y. Li, and N.J. Torok Apoptotic body engulfment by hepatic stellate cells promotes their survival by the JAK/STAT and Akt/NF-kappaB-dependent pathways J Hepatol 51 2009 139 148
-
(2009)
J Hepatol
, vol.51
, pp. 139-148
-
-
Jiang, J.X.1
Mikami, K.2
Venugopal, S.3
Li, Y.4
Torok, N.J.5
-
366
-
-
34548186667
-
Cellular senescence: When bad things happen to good cells
-
J. Campisi, and F. d'Adda di Fagagna Cellular senescence: when bad things happen to good cells Nat Rev Mol Cell Biol 8 2007 729 740
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 729-740
-
-
Campisi, J.1
D'Adda Di Fagagna, F.2
-
367
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
-
M. Serrano, A.W. Lin, M.E. McCurrach, D. Beach, and S.W. Lowe Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a Cell 88 1997 593 602
-
(1997)
Cell
, vol.88
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
368
-
-
18444374159
-
Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis
-
S.U. Wiemann, A. Satyanarayana, M. Tsahuridu, H.L. Tillmann, L. Zender, and J. Klempnauer Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis FASEB J 16 2002 935 942
-
(2002)
FASEB J
, vol.16
, pp. 935-942
-
-
Wiemann, S.U.1
Satyanarayana, A.2
Tsahuridu, M.3
Tillmann, H.L.4
Zender, L.5
Klempnauer, J.6
-
369
-
-
49749145668
-
Senescence of activated stellate cells limits liver fibrosis
-
V. Krizhanovsky, M. Yon, R.A. Dickins, S. Hearn, J. Simon, and C. Miething Senescence of activated stellate cells limits liver fibrosis Cell 134 2008 657 667
-
(2008)
Cell
, vol.134
, pp. 657-667
-
-
Krizhanovsky, V.1
Yon, M.2
Dickins, R.A.3
Hearn, S.4
Simon, J.5
Miething, C.6
-
370
-
-
2642545495
-
Basement membrane-like matrix inhibits proliferation and collagen synthesis by activated rat hepatic stellate cells: Evidence for matrix-dependent deactivation of stellate cells
-
M.D. Gaca, X. Zhou, R. Issa, K. Kiriella, J.P. Iredale, and R.C. Benyon Basement membrane-like matrix inhibits proliferation and collagen synthesis by activated rat hepatic stellate cells: evidence for matrix-dependent deactivation of stellate cells Matrix Biol 22 2003 229 239
-
(2003)
Matrix Biol
, vol.22
, pp. 229-239
-
-
Gaca, M.D.1
Zhou, X.2
Issa, R.3
Kiriella, K.4
Iredale, J.P.5
Benyon, R.C.6
-
371
-
-
0036022840
-
Reversal of activation of human myofibroblast-like cells by culture on a basement membrane-like substrate
-
N. Sohara, I. Znoyko, M.T. Levy, M. Trojanowska, and A. Reuben Reversal of activation of human myofibroblast-like cells by culture on a basement membrane-like substrate J Hepatol 37 2002 214 221
-
(2002)
J Hepatol
, vol.37
, pp. 214-221
-
-
Sohara, N.1
Znoyko, I.2
Levy, M.T.3
Trojanowska, M.4
Reuben, A.5
-
372
-
-
13844297246
-
PPAR gamma and hepatic stellate cells
-
S. Hazra, T. Miyahara, R.A. Rippe, and H. Tsukamoto PPAR gamma and hepatic stellate cells Comp Hepatol 3 Suppl. 1 2004 S7
-
(2004)
Comp Hepatol
, vol.3
, Issue.SUPPL. 1
, pp. 7
-
-
Hazra, S.1
Miyahara, T.2
Rippe, R.A.3
Tsukamoto, H.4
-
373
-
-
59849084351
-
Over-expressed microRNA-27a and 27b influence fat accumulation and cell proliferation during rat hepatic stellate cell activation
-
J. Ji, J. Zhang, G. Huang, J. Qian, X. Wang, and S. Mei Over-expressed microRNA-27a and 27b influence fat accumulation and cell proliferation during rat hepatic stellate cell activation FEBS Lett 583 2009 759 766
-
(2009)
FEBS Lett
, vol.583
, pp. 759-766
-
-
Ji, J.1
Zhang, J.2
Huang, G.3
Qian, J.4
Wang, X.5
Mei, S.6
-
374
-
-
33751248252
-
Direct and indirect evidence for the reversibility of cirrhosis
-
J. Serpaggi, F. Carnot, B. Nalpas, D. Canioni, J. Guechot, and P. Lebray Direct and indirect evidence for the reversibility of cirrhosis Hum Pathol 37 2006 1519 1526
-
(2006)
Hum Pathol
, vol.37
, pp. 1519-1526
-
-
Serpaggi, J.1
Carnot, F.2
Nalpas, B.3
Canioni, D.4
Guechot, J.5
Lebray, P.6
-
375
-
-
33747042226
-
Reversibility of hepatic fibrosis in treated genetic hemochromatosis: A study of 36 cases
-
L. Falize, A. Guillygomarc'h, M. Perrin, F. Laine, D. Guyader, and P. Brissot Reversibility of hepatic fibrosis in treated genetic hemochromatosis: a study of 36 cases Hepatology 44 2006 472 477
-
(2006)
Hepatology
, vol.44
, pp. 472-477
-
-
Falize, L.1
Guillygomarc'H, A.2
Perrin, M.3
Laine, F.4
Guyader, D.5
Brissot, P.6
-
376
-
-
16644402719
-
Expression of matrix metalloproteinase-2 and -14 persists during early resolution of experimental liver fibrosis and might contribute to fibrolysis
-
X. Zhou, C.J. Hovell, S. Pawley, M.I. Hutchings, M.J. Arthur, and J.P. Iredale Expression of matrix metalloproteinase-2 and -14 persists during early resolution of experimental liver fibrosis and might contribute to fibrolysis Liver Int 24 2004 492 501
-
(2004)
Liver Int
, vol.24
, pp. 492-501
-
-
Zhou, X.1
Hovell, C.J.2
Pawley, S.3
Hutchings, M.I.4
Arthur, M.J.5
Iredale, J.P.6
|