Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans

Journal of Clinical Investigation

Volumn 118, Issue 10, 2008, Pages 3331-3342

  Omenetti, Alessia ^a   Porrello, Alessandro ^b   Jung, Youngmi ^a   Yang, Liu ^a   Popov, Yury ^c,d   Choi, Steve S ^a   Witek, Rafal P ^a   Alpini, Gianfranco ^e,f   Venter, Juliet ^f   Vandongen, Hendrika M ^a   Syn, Wing Kin ^a   Baroni, Gianluca Svegliati ^g   Benedetti, Antonio ^g   Schuppan, Detlef ^c   Diehl, Anna Mae ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b DUKE UNIVERSITY   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^e VETERANS AFFAIRS MEDICAL CENTER   (United States)

^f TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^g UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

NEUTRALIZING ANTIBODY; SONIC HEDGEHOG PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BILE DUCT; BILE DUCT INJURY; BILE DUCT LIGATION; BILE DUCT OBSTRUCTION; BILIARY TRACT FIBROSIS; CELL ISOLATION; CELL MIGRATION; CHOLESTASIS; CLINICAL ARTICLE; COCULTURE; CONTROLLED STUDY; EPITHELIUM; HUMAN; MALE; MESENCHYME; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; STELLATE CELL;

ANIMALS; BILE DUCTS, INTRAHEPATIC; CELL LINE; CHOLESTASIS, INTRAHEPATIC; EPITHELIUM; FIBROBLASTS; FIBROSIS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HEDGEHOG PROTEINS; HUMANS; LIGANDS; LIVER CIRRHOSIS, BILIARY; MALE; MESODERM; MICE; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 55849135600     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI35875     Document Type: Article

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