-
1
-
-
0025297039
-
Epithelial cell-fibroblast interactions in lung injury and repair
-
Adamson IY, Hedgecock C, Bowden DH. Epithelial cell-fibroblast interactions in lung injury and repair. Am J Pathol 137: 385-392, 1990.
-
(1990)
Am J Pathol
, vol.137
, pp. 385-392
-
-
Adamson, I.Y.1
Hedgecock, C.2
Bowden, D.H.3
-
2
-
-
0015992802
-
The type 2 cell as progenitor of alveolar epithelial regeneration. A cytodynamic study in mice after exposure to oxygen
-
Adamson IY, Bowden DH. The type 2 cell as progenitor of alveolar epithelial regeneration. A cytodynamic study in mice after exposure to oxygen. Lab Invest 30: 35-42, 1974.
-
(1974)
Lab Invest
, vol.30
, pp. 35-42
-
-
Adamson, I.Y.1
Bowden, D.H.2
-
3
-
-
0023854506
-
Relationship of alveolar epithelial injury and repair to the induction of pulmonary fibrosis
-
Adamson IY, Young L, Bowden DH. Relationship of alveolar epithelial injury and repair to the induction of pulmonary fibrosis. Am J Pathol 130: 377-383, 1988.
-
(1988)
Am J Pathol
, vol.130
, pp. 377-383
-
-
Adamson, I.Y.1
Young, L.2
Bowden, D.H.3
-
4
-
-
0027944596
-
Potential applications of apoptosis in modifying the biological behavior of therapeutically refractory cancers
-
Anderson KM, Harris JE, Bonomi P. Potential applications of apoptosis in modifying the biological behavior of therapeutically refractory cancers. Med Hypotheses 43: 207-213, 1994.
-
(1994)
Med Hypotheses
, vol.43
, pp. 207-213
-
-
Anderson, K.M.1
Harris, J.E.2
Bonomi, P.3
-
5
-
-
0025053989
-
Platelet-derived growth factor in idiopathic pulmonary fibrosis
-
Antoniades HN, Bravo MA, Avila RE, Galanopoulos T, Neville-Golden J, Maxwell M, Selman M. Platelet-derived growth factor in idiopathic pulmonary fibrosis. J Clin Invest 86: 1055-1064, 1990.
-
(1990)
J Clin Invest
, vol.86
, pp. 1055-1064
-
-
Antoniades, H.N.1
Bravo, M.A.2
Avila, R.E.3
Galanopoulos, T.4
Neville-Golden, J.5
Maxwell, M.6
Selman, M.7
-
6
-
-
0034711307
-
Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration
-
Bakin AV, Tomlinson AK, Bhowmick NA, Moses HL, Arteaga CL. Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration. J Biol Chem 275: 36803-36810, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 36803-36810
-
-
Bakin, A.V.1
Tomlinson, A.K.2
Bhowmick, N.A.3
Moses, H.L.4
Arteaga, C.L.5
-
7
-
-
0035141395
-
Evidence of type II pneumocyte apoptosis in the pathogenesis of idiopathic pulmonary fibrosis (IFP)/usual interstitial pneumonia (UIP)
-
Barbas-Filho JV, Ferreira MA, Sesso A, Kairalla RA, Carvalho CR, Capelozzi VL. Evidence of type II pneumocyte apoptosis in the pathogenesis of idiopathic pulmonary fibrosis (IFP)/usual interstitial pneumonia (UIP). J Clin Pathol 54: 132-138, 2001.
-
(2001)
J Clin Pathol
, vol.54
, pp. 132-138
-
-
Barbas-Filho, J.V.1
Ferreira, M.A.2
Sesso, A.3
Kairalla, R.A.4
Carvalho, C.R.5
Capelozzi, V.L.6
-
8
-
-
0037572319
-
Tumor necrosis factor-α stimulates the epithelial-to-mesenchymal transition of human colonic organoids
-
Bates RC, Mercurio AM. Tumor necrosis factor-α stimulates the epithelial-to-mesenchymal transition of human colonic organoids. Mol Biol Cell 14: 1790-1800, 2003.
-
(2003)
Mol Biol Cell
, vol.14
, pp. 1790-1800
-
-
Bates, R.C.1
Mercurio, A.M.2
-
9
-
-
0035185853
-
Transforming growth factor-β1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism
-
Bhowmick NA, Ghiassi M, Bakin A, Aakre M, Lundquist CA, Engel ME, Arteaga CL, Moses HL. Transforming growth factor-β1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism. Mol Biol Cell 12: 27-36, 2001.
-
(2001)
Mol Biol Cell
, vol.12
, pp. 27-36
-
-
Bhowmick, N.A.1
Ghiassi, M.2
Bakin, A.3
Aakre, M.4
Lundquist, C.A.5
Engel, M.E.6
Arteaga, C.L.7
Moses, H.L.8
-
10
-
-
33751582928
-
Snail activation disrupts tissue homeostasis and induces fibrosis in the adult kidney
-
Boutet A, De Frutos CA, Maxwell PH, Mayol MJ, Romero J, Nieto MA. Snail activation disrupts tissue homeostasis and induces fibrosis in the adult kidney. EMBO J 25: 5603-5613, 2006.
-
(2006)
EMBO J
, vol.25
, pp. 5603-5613
-
-
Boutet, A.1
De Frutos, C.A.2
Maxwell, P.H.3
Mayol, M.J.4
Romero, J.5
Nieto, M.A.6
-
11
-
-
0033560169
-
TGFbeta2 and TGFbeta3 have separate and sequential activities during epithelial-mesenchymal transformation in embryonic heart
-
Boyer AS, Ayerinskas II, Vincent EB, McKinney LA, Weeks DL, Runyan RB. TGFbeta2 and TGFbeta3 have separate and sequential activities during epithelial-mesenchymal transformation in embryonic heart. Dev Biol 208: 530-545, 1999.
-
(1999)
Dev Biol
, vol.208
, pp. 530-545
-
-
Boyer, A.S.1
Ayerinskas, I.I.2
Vincent, E.B.3
McKinney, L.A.4
Weeks, D.L.5
Runyan, R.B.6
-
12
-
-
0033784843
-
The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
-
Cano A, Perez-Moreno M, Rodrigo I, Locascio A, Blanco M, del Barr M, Portillo F, Nieto M. The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat Cell Biol 2: 76-83, 2000.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 76-83
-
-
Cano, A.1
Perez-Moreno, M.2
Rodrigo, I.3
Locascio, A.4
Blanco, M.5
del Barr, M.6
Portillo, F.7
Nieto, M.8
-
13
-
-
0038582623
-
Gelatinase A (MMP-2) is necessary and sufficient for renal tubular cell epithelial-mesenchymal transformation
-
Cheng S, Lovett DH. Gelatinase A (MMP-2) is necessary and sufficient for renal tubular cell epithelial-mesenchymal transformation. Am J Pathol 162: 1937-1949, 2003.
-
(2003)
Am J Pathol
, vol.162
, pp. 1937-1949
-
-
Cheng, S.1
Lovett, D.H.2
-
14
-
-
33845787629
-
Snail is required for transforming growth factor-beta-induced epithelial-mesenchymal transition by activating PI3 kinase/Akt signal pathway
-
Cho HJ, Baek KE, Saika S, Jeong MJ, Yoo J. Snail is required for transforming growth factor-beta-induced epithelial-mesenchymal transition by activating PI3 kinase/Akt signal pathway. Biochem Biophys Res Commun 353: 337-343, 2007.
-
(2007)
Biochem Biophys Res Commun
, vol.353
, pp. 337-343
-
-
Cho, H.J.1
Baek, K.E.2
Saika, S.3
Jeong, M.J.4
Yoo, J.5
-
15
-
-
26444560222
-
Induction of an epithelial to mesenchymal transition in human immortal and malignant keratinocytes by TGF-beta1 involves MAPK, Smad and AP-1 signalling pathways
-
Davies M, Robinson M, Smith E, Huntley S, Prime S, Paterson I. Induction of an epithelial to mesenchymal transition in human immortal and malignant keratinocytes by TGF-beta1 involves MAPK, Smad and AP-1 signalling pathways. J Cell Biochem 95: 918-931, 2005.
-
(2005)
J Cell Biochem
, vol.95
, pp. 918-931
-
-
Davies, M.1
Robinson, M.2
Smith, E.3
Huntley, S.4
Prime, S.5
Paterson, I.6
-
16
-
-
0036587571
-
Transforming growth factor β signal transduction
-
Dennler S, Goumans MJ, ten Dijke P. Transforming growth factor β signal transduction. J Leukoc Biol 71: 731-740, 2002.
-
(2002)
J Leukoc Biol
, vol.71
, pp. 731-740
-
-
Dennler, S.1
Goumans, M.J.2
ten Dijke, P.3
-
17
-
-
0142104985
-
Smad-dependent and Smad-independent pathways in TGF-beta family signalling
-
Derynck R, Zhang YE. Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature 425: 577-584, 2003.
-
(2003)
Nature
, vol.425
, pp. 577-584
-
-
Derynck, R.1
Zhang, Y.E.2
-
18
-
-
33646594714
-
TGF-beta1-induced EMT can occur independently of its proapoptotic effects and is aided by EGF receptor activation
-
Docherty NG, O'Sullivan OE, Healy DA, Murphy M, O'Neill AJ, Fitzpatrick JM, Watson RW. TGF-beta1-induced EMT can occur independently of its proapoptotic effects and is aided by EGF receptor activation. Am J Physiol Renal Physiol 290: F1202-F1212, 2006.
-
(2006)
Am J Physiol Renal Physiol
, vol.290
-
-
Docherty, N.G.1
O'Sullivan, O.E.2
Healy, D.A.3
Murphy, M.4
O'Neill, A.J.5
Fitzpatrick, J.M.6
Watson, R.W.7
-
19
-
-
0032842887
-
Transforming growth factor-β regulates tubular epithelial- myofibroblast transdifferentiation in vitro
-
Fan JM, Ng YY, Hill PA, Nikolic-Paterson DJ, Mu W, Atkins RC, Lan HY. Transforming growth factor-β regulates tubular epithelial- myofibroblast transdifferentiation in vitro. Kidney Int 56: 1455-1467, 1999.
-
(1999)
Kidney Int
, vol.56
, pp. 1455-1467
-
-
Fan, J.M.1
Ng, Y.Y.2
Hill, P.A.3
Nikolic-Paterson, D.J.4
Mu, W.5
Atkins, R.C.6
Lan, H.Y.7
-
20
-
-
2542609844
-
Smad3 as a mediator of the fibrotic response
-
Flanders KC. Smad3 as a mediator of the fibrotic response. Int J Exp Pathol 85: 47-64, 2004.
-
(2004)
Int J Exp Pathol
, vol.85
, pp. 47-64
-
-
Flanders, K.C.1
-
21
-
-
0027213101
-
Expression of endothelin-1 in lungs of patients with cryptogenic fibrosing alveolitis
-
Giaid A, Michel RP, Stewart DJ, Sheppard M, Corrin B, Hamid Q. Expression of endothelin-1 in lungs of patients with cryptogenic fibrosing alveolitis. Lancet 341: 1550-1554, 1993.
-
(1993)
Lancet
, vol.341
, pp. 1550-1554
-
-
Giaid, A.1
Michel, R.P.2
Stewart, D.J.3
Sheppard, M.4
Corrin, B.5
Hamid, Q.6
-
22
-
-
0028931948
-
Immunocytochemical distribution of the calcium-binding protein p9Ka in normal rat tissues: Variation in the cellular location in different tissues
-
Gibbs FE, Barraclough R, Platt-Higgins A, Rudland PS, Wilkinson MC, Parry EW. Immunocytochemical distribution of the calcium-binding protein p9Ka in normal rat tissues: variation in the cellular location in different tissues. J Histochem Cytochem 43: 169-180, 1995.
-
(1995)
J Histochem Cytochem
, vol.43
, pp. 169-180
-
-
Gibbs, F.E.1
Barraclough, R.2
Platt-Higgins, A.3
Rudland, P.S.4
Wilkinson, M.C.5
Parry, E.W.6
-
23
-
-
0020358296
-
Epithelia suspended in collagen gels can lose polarity and express characteristics of migrating mesenchymal cells
-
Greenburg G, Hay ED. Epithelia suspended in collagen gels can lose polarity and express characteristics of migrating mesenchymal cells. J Cell Biol 95: 333-339, 1982.
-
(1982)
J Cell Biol
, vol.95
, pp. 333-339
-
-
Greenburg, G.1
Hay, E.D.2
-
24
-
-
0037728809
-
The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines
-
Grille SJ, Bellacosa A, Upson J, Klein-Szanto AJ, van Roy F, Lee-Kwon W, Donowitz M, Tsichlis PN, Larue L. The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines. Cancer Res 63: 2172-2178, 2003.
-
(2003)
Cancer Res
, vol.63
, pp. 2172-2178
-
-
Grille, S.J.1
Bellacosa, A.2
Upson, J.3
Klein-Szanto, A.J.4
van Roy, F.5
Lee-Kwon, W.6
Donowitz, M.7
Tsichlis, P.N.8
Larue, L.9
-
25
-
-
0028567054
-
TGF-beta 1 induces lens cells to accumulate alpha-smooth muscle actin, a marker for subcapsular cataracts
-
Hales AM, Schulz MW, Chamberlain CG, McAvoy JW. TGF-beta 1 induces lens cells to accumulate alpha-smooth muscle actin, a marker for subcapsular cataracts. Curr Eye Res 13: 885-890, 1994.
-
(1994)
Curr Eye Res
, vol.13
, pp. 885-890
-
-
Hales, A.M.1
Schulz, M.W.2
Chamberlain, C.G.3
McAvoy, J.W.4
-
26
-
-
0029553183
-
An overview of epithelio-mesenchymal transformation
-
Hay ED. An overview of epithelio-mesenchymal transformation. Acta Anat 154: 8-20, 1995.
-
(1995)
Acta Anat
, vol.154
, pp. 8-20
-
-
Hay, E.D.1
-
27
-
-
23044457914
-
Antibodies against macrophages that overlap in specificity with fibroblasts
-
Inoue T, Plieth D, Venkov CD, Xu C, Neilson EG. Antibodies against macrophages that overlap in specificity with fibroblasts. Kidney Int 67: 2488-2493, 2005.
-
(2005)
Kidney Int
, vol.67
, pp. 2488-2493
-
-
Inoue, T.1
Plieth, D.2
Venkov, C.D.3
Xu, C.4
Neilson, E.G.5
-
28
-
-
0037423374
-
Elucidation of Smad requirement in transforming growth factor-beta type I receptor-induced responses
-
Itoh S, Thorikay M, Kowanetz M, Moustakas A, Itoh F, Heldin CH, ten Dijke P. Elucidation of Smad requirement in transforming growth factor-beta type I receptor-induced responses. J Biol Chem 278: 3751-3761, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 3751-3761
-
-
Itoh, S.1
Thorikay, M.2
Kowanetz, M.3
Moustakas, A.4
Itoh, F.5
Heldin, C.H.6
ten Dijke, P.7
-
29
-
-
0036322007
-
Evidence that fibroblasts derive from epithelium during tissue fibrosis
-
Iwano M, Plieth D, Danoff TM, Xue C, Okada H, Neilson EG. Evidence that fibroblasts derive from epithelium during tissue fibrosis. J Clin Invest 110: 341-350, 2002.
-
(2002)
J Clin Invest
, vol.110
, pp. 341-350
-
-
Iwano, M.1
Plieth, D.2
Danoff, T.M.3
Xue, C.4
Okada, H.5
Neilson, E.G.6
-
30
-
-
0030872483
-
Alterations in cytokeratin expression by the alveolar lining epithelial cells in lung tissues from patients with idiopathic pulmonary fibrosis
-
Iyonaga K, Miyajima M, Suga M, Saita N, Ando M. Alterations in cytokeratin expression by the alveolar lining epithelial cells in lung tissues from patients with idiopathic pulmonary fibrosis. J Pathol 182: 217-224, 1997.
-
(1997)
J Pathol
, vol.182
, pp. 217-224
-
-
Iyonaga, K.1
Miyajima, M.2
Suga, M.3
Saita, N.4
Ando, M.5
-
31
-
-
0028302742
-
Monocyte chemoattractant protein-1 in idiopathic pulmonary fibrosis and other interstitial lung diseases
-
Iyonaga K, Takeya M, Saita N, Sakamoto O, Yoshimura T, Ando M, Takahashi K. Monocyte chemoattractant protein-1 in idiopathic pulmonary fibrosis and other interstitial lung diseases. Hum Pathol 25: 455-463, 1994.
-
(1994)
Hum Pathol
, vol.25
, pp. 455-463
-
-
Iyonaga, K.1
Takeya, M.2
Saita, N.3
Sakamoto, O.4
Yoshimura, T.5
Ando, M.6
Takahashi, K.7
-
32
-
-
0037148532
-
Ras and TGFβ cooperatively regulate epithelial cell plasticity and metastasis: Dissection of Ras signaling pathways
-
Janda E, Lehmann K, Killisch I, Jechlinger M, Herzig M, Downward J, Beug H, Grunert S. Ras and TGFβ cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways. J Cell Biol 156: 299-313, 2002.
-
(2002)
J Cell Biol
, vol.156
, pp. 299-313
-
-
Janda, E.1
Lehmann, K.2
Killisch, I.3
Jechlinger, M.4
Herzig, M.5
Downward, J.6
Beug, H.7
Grunert, S.8
-
33
-
-
24344483881
-
Upregulation of MMP-9 in MDCK epithelial cell line in response to expression of the Snail transcription factor
-
Jorda M, Olmeda D, Vinyals A, Valero E, Cubillo E, Llorens A, Cano A, Fabra A. Upregulation of MMP-9 in MDCK epithelial cell line in response to expression of the Snail transcription factor. J Cell Sci 117: 3371-3385, 2005.
-
(2005)
J Cell Sci
, vol.117
, pp. 3371-3385
-
-
Jorda, M.1
Olmeda, D.2
Vinyals, A.3
Valero, E.4
Cubillo, E.5
Llorens, A.6
Cano, A.7
Fabra, A.8
-
34
-
-
30644479959
-
Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation
-
Ju W, Ogawa A, Heyer J, Nierhof D, Yu L, Kucherlapati R, Shafritz DA, Bottinger EP. Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation. Mol Cell Biol 26: 654-667, 2006.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 654-667
-
-
Ju, W.1
Ogawa, A.2
Heyer, J.3
Nierhof, D.4
Yu, L.5
Kucherlapati, R.6
Shafritz, D.A.7
Bottinger, E.P.8
-
35
-
-
0346724511
-
Epithelial-mesenchymal transition and its implications for fibrosis
-
Kalluri R, Neilson EG. Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest 112: 1776-1784, 2003.
-
(2003)
J Clin Invest
, vol.112
, pp. 1776-1784
-
-
Kalluri, R.1
Neilson, E.G.2
-
36
-
-
0028885803
-
Cytoskeletal protein modulation in pulmonary alveolar myofibroblasts during idiopathic pulmonary fibrosis. Possible role of transforming growth factor beta and tumor necrosis factor
-
Kapanci Y, Desmouliere A, Pache J, Redard M, Gabbiani G. Cytoskeletal protein modulation in pulmonary alveolar myofibroblasts during idiopathic pulmonary fibrosis. Possible role of transforming growth factor beta and tumor necrosis factor. Am J Respir Crit Care Med 152: 2163-2169, 1994.
-
(1994)
Am J Respir Crit Care Med
, vol.152
, pp. 2163-2169
-
-
Kapanci, Y.1
Desmouliere, A.2
Pache, J.3
Redard, M.4
Gabbiani, G.5
-
37
-
-
26244458018
-
TGF-β1 induces human alveolar epithelial to mesenchymal cell transition (EMT)
-
Kasai H, Allen JT, Mason RM, Kamimura T, Zhang Z. TGF-β1 induces human alveolar epithelial to mesenchymal cell transition (EMT). Respir Res 6: 56, 2005.
-
(2005)
Respir Res
, vol.6
, pp. 56
-
-
Kasai, H.1
Allen, J.T.2
Mason, R.M.3
Kamimura, T.4
Zhang, Z.5
-
38
-
-
0029866586
-
Alterations in the alveolar epithelium after injury leading to pulmonary fibrosis
-
Kasper M, Haroske G. Alterations in the alveolar epithelium after injury leading to pulmonary fibrosis. Histol Histopathol 11: 463-483, 1996.
-
(1996)
Histol Histopathol
, vol.11
, pp. 463-483
-
-
Kasper, M.1
Haroske, G.2
-
39
-
-
0036891960
-
Usual interstitial pneumonia: Histologic study of biopsy and explant specimens
-
Katzenstein AL, Zisman DA, Litzky LA, Nguyen BT, Kotloff RM. Usual interstitial pneumonia: histologic study of biopsy and explant specimens. Am J Surg Pathol 26: 1567-1577, 2002.
-
(2002)
Am J Surg Pathol
, vol.26
, pp. 1567-1577
-
-
Katzenstein, A.L.1
Zisman, D.A.2
Litzky, L.A.3
Nguyen, B.T.4
Kotloff, R.M.5
-
40
-
-
0026210618
-
Increased production and immunohistochemical localization of transforming growth factor-beta in idiopathic pulmonary fibrosis
-
Khalil N, O'Connor R, Unruh H, Warren P, Flanders K, Kemp A, Bereznay O, Greenberg A. Increased production and immunohistochemical localization of transforming growth factor-beta in idiopathic pulmonary fibrosis. Am J Respir Cell Mol Biol 5: 155-162, 1991.
-
(1991)
Am J Respir Cell Mol Biol
, vol.5
, pp. 155-162
-
-
Khalil, N.1
O'Connor, R.2
Unruh, H.3
Warren, P.4
Flanders, K.5
Kemp, A.6
Bereznay, O.7
Greenberg, A.8
-
41
-
-
0030076509
-
TGF-beta 1, but not TGF-beta 2 or TGF-beta 3, is differentially present in epithelial cells of advanced pulmonary fibrosis: An immunohistochemical study
-
Khalil N, O'Connor RN, Flanders KC, Unruh H. TGF-beta 1, but not TGF-beta 2 or TGF-beta 3, is differentially present in epithelial cells of advanced pulmonary fibrosis: an immunohistochemical study. Am J Respir Cell Mol Biol 14: 131-138, 1996.
-
(1996)
Am J Respir Cell Mol Biol
, vol.14
, pp. 131-138
-
-
Khalil, N.1
O'Connor, R.N.2
Flanders, K.C.3
Unruh, H.4
-
42
-
-
0035181092
-
Regulation of the effects of TGF-β1 by activation of latent TGF-β1 and differential expression of TGF-β receptors (TβR-I and TβR-II) in idiopathic pulmonary fibrosis
-
Khalil N, Parekh TV, O'Connor R, Antman N, Kepron W, Yehaulaeshet T, Xu YD, Gold LI. Regulation of the effects of TGF-β1 by activation of latent TGF-β1 and differential expression of TGF-β receptors (TβR-I and TβR-II) in idiopathic pulmonary fibrosis. Thorax 56: 907-915, 2001.
-
(2001)
Thorax
, vol.56
, pp. 907-915
-
-
Khalil, N.1
Parekh, T.V.2
O'Connor, R.3
Antman, N.4
Kepron, W.5
Yehaulaeshet, T.6
Xu, Y.D.7
Gold, L.I.8
-
43
-
-
20444397431
-
Identification of bronchioalveolar stem cells in normal lung and lung cancer
-
Kim CF, Jackson EL, Woolfenden AE, Lawrence S, Babar I, Vogel S, Crowley D, Bronson RT, Jacks T. Identification of bronchioalveolar stem cells in normal lung and lung cancer. Cell 121: 823-835, 2005.
-
(2005)
Cell
, vol.121
, pp. 823-835
-
-
Kim, C.F.1
Jackson, E.L.2
Woolfenden, A.E.3
Lawrence, S.4
Babar, I.5
Vogel, S.6
Crowley, D.7
Bronson, R.T.8
Jacks, T.9
-
44
-
-
0035991607
-
Direct evidence for a role of β-catenin/LEF-1 signaling pathway in induction of EMT
-
Kim K, Lu Z, Hay ED. Direct evidence for a role of β-catenin/LEF-1 signaling pathway in induction of EMT. Cell Biol Int 26: 463-476, 2002.
-
(2002)
Cell Biol Int
, vol.26
, pp. 463-476
-
-
Kim, K.1
Lu, Z.2
Hay, E.D.3
-
45
-
-
33748375828
-
Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix
-
Kim KK, Kugler MC, Wolters PJ, Robillard L, Galvez MG, Brumwell AN, Sheppard D, Chapman HA. Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix. Proc Natl Acad Sci USA 103: 13180-13185, 2006.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 13180-13185
-
-
Kim, K.K.1
Kugler, M.C.2
Wolters, P.J.3
Robillard, L.4
Galvez, M.G.5
Brumwell, A.N.6
Sheppard, D.7
Chapman, H.A.8
-
46
-
-
5044248294
-
A role for Id in the regulation of TGF-beta-induced epithelial-mesenchymal transdifferentiation
-
Kondo M, Cubillo E, Tobiume K, Shirakihara T, Fukuda N, Suzuki H, Shimizu K, Takehara K, Cano A, Saitoh M, Miyazono K. A role for Id in the regulation of TGF-beta-induced epithelial-mesenchymal transdifferentiation. Cell Death Differ 11: 1092-1101, 2004.
-
(2004)
Cell Death Differ
, vol.11
, pp. 1092-1101
-
-
Kondo, M.1
Cubillo, E.2
Tobiume, K.3
Shirakihara, T.4
Fukuda, N.5
Suzuki, H.6
Shimizu, K.7
Takehara, K.8
Cano, A.9
Saitoh, M.10
Miyazono, K.11
-
47
-
-
0028929665
-
Increased procoagulant and antifibrinolytic activities in the lungs with idiopathic pulmonary fibrosis
-
Kotani I, Sato A, Hayakawa H, Urano T, Takada Y, Takada A. Increased procoagulant and antifibrinolytic activities in the lungs with idiopathic pulmonary fibrosis. Thromb Res 77: 493-504, 1995.
-
(1995)
Thromb Res
, vol.77
, pp. 493-504
-
-
Kotani, I.1
Sato, A.2
Hayakawa, H.3
Urano, T.4
Takada, Y.5
Takada, A.6
-
48
-
-
2942536704
-
Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor beta and bone morphogenetic protein
-
Kowanetz M, Valcourt U, Bergstrom R, Heldin CH, Moustakas A. Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor beta and bone morphogenetic protein. Mol Cell Biol 24: 4241-4254, 2004.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 4241-4254
-
-
Kowanetz, M.1
Valcourt, U.2
Bergstrom, R.3
Heldin, C.H.4
Moustakas, A.5
-
49
-
-
0030215822
-
p21Waf1/Cip1/Sdi1 and p53 expression in association with DNA strand breaks in idiopathic pulmonary fibrosis
-
Kuwano K, Kunitake R, Kawasaki M, Nomoto Y, Hagimoto N, Nakanishi Y, Hara N. p21Waf1/Cip1/Sdi1 and p53 expression in association with DNA strand breaks in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 154: 477-483, 1996.
-
(1996)
Am J Respir Crit Care Med
, vol.154
, pp. 477-483
-
-
Kuwano, K.1
Kunitake, R.2
Kawasaki, M.3
Nomoto, Y.4
Hagimoto, N.5
Nakanishi, Y.6
Hara, N.7
-
50
-
-
23944522749
-
Microarray analysis of gene expression during epithelial-mesenchymal transformation
-
LaGamba D, Nawshad A, Hay ED. Microarray analysis of gene expression during epithelial-mesenchymal transformation. Dev Dyn 234: 132-142, 2005.
-
(2005)
Dev Dyn
, vol.234
, pp. 132-142
-
-
LaGamba, D.1
Nawshad, A.2
Hay, E.D.3
-
51
-
-
21544440606
-
Characterization of renal interstitial fibroblast-specific protein 1/S100A4-positive cells in healthy and inflamed rodent kidneys
-
Le Hir M, Hegyi I, Cueni-Loffing D, Loffing J, Kaissling B. Characterization of renal interstitial fibroblast-specific protein 1/S100A4-positive cells in healthy and inflamed rodent kidneys. Histochem Cell Biol 123: 335-346, 2005.
-
(2005)
Histochem Cell Biol
, vol.123
, pp. 335-346
-
-
Le Hir, M.1
Hegyi, I.2
Cueni-Loffing, D.3
Loffing, J.4
Kaissling, B.5
-
52
-
-
33645302628
-
The epithelial- mesenchymal transition: New insights in signaling, development, and disease
-
Lee JM, Dedhar S, Kalluri R, Thompson EW. The epithelial- mesenchymal transition: new insights in signaling, development, and disease. J Cell Biol 172: 973-981, 2006.
-
(2006)
J Cell Biol
, vol.172
, pp. 973-981
-
-
Lee, J.M.1
Dedhar, S.2
Kalluri, R.3
Thompson, E.W.4
-
53
-
-
0141720342
-
Role for integrin-linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis
-
Li Y, Yang J, Dai C, Wu C, Liu Y. Role for integrin-linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis. J Clin Invest 112: 503-516, 2003.
-
(2003)
J Clin Invest
, vol.112
, pp. 503-516
-
-
Li, Y.1
Yang, J.2
Dai, C.3
Wu, C.4
Liu, Y.5
-
54
-
-
33846684874
-
Tubular epithelial cell dedifferentiation is driven by the helix-loop-helix transcriptional inhibitor Id1
-
Li Y, Yang J, Luo JH, Dedhar S, Liu Y. Tubular epithelial cell dedifferentiation is driven by the helix-loop-helix transcriptional inhibitor Id1. J Am Soc Nephrol 18: 449-460, 2007.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 449-460
-
-
Li, Y.1
Yang, J.2
Luo, J.H.3
Dedhar, S.4
Liu, Y.5
-
55
-
-
0347993932
-
Epithelial to mesenchymal transition in renal fibrogenesis: Pathologic significance, molecular mechanism, and therapeutic intervention
-
Liu Y. Epithelial to mesenchymal transition in renal fibrogenesis: pathologic significance, molecular mechanism, and therapeutic intervention. J Am Soc Nephrol 15: 1-12, 2004.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 1-12
-
-
Liu, Y.1
-
56
-
-
0028339010
-
Transforming growth factor-β induces a chondroitin sulfate/dermatan sulfate proteoglycan in alveolar type II cells
-
Maniscalco WM, Campbell MH. Transforming growth factor-β induces a chondroitin sulfate/dermatan sulfate proteoglycan in alveolar type II cells. Am J Physiol Lung Cell Mol Physiol 266: L672-L680, 1994.
-
(1994)
Am J Physiol Lung Cell Mol Physiol
, vol.266
-
-
Maniscalco, W.M.1
Campbell, M.H.2
-
58
-
-
10744229444
-
Transdifferentiation of cultured tubular cells induced by hypoxia
-
Manotham K, Tanaka T, Matsumoto M, Ohse T, Inagi R, Miyata T, Kurokawa K, Fujita T, Ingelfinger JR, Nangaku M. Transdifferentiation of cultured tubular cells induced by hypoxia. Kidney Int 65: 871-880, 2004.
-
(2004)
Kidney Int
, vol.65
, pp. 871-880
-
-
Manotham, K.1
Tanaka, T.2
Matsumoto, M.3
Ohse, T.4
Inagi, R.5
Miyata, T.6
Kurokawa, K.7
Fujita, T.8
Ingelfinger, J.R.9
Nangaku, M.10
-
59
-
-
0037405501
-
Central role for Rho in TGF-β1-induced α-smooth muscle actin expression during epithelial-mesenchymal transition
-
Masszi A, Di Ciano C, Sirokmany G, Arthur WT, Rotstein OD, Wang J, McCulloch CAG, Rosivall L, Mucsi I, Kapus A. Central role for Rho in TGF-β1-induced α-smooth muscle actin expression during epithelial-mesenchymal transition. Am J Physiol Renal Physiol 284: F911-F924, 2003.
-
(2003)
Am J Physiol Renal Physiol
, vol.284
-
-
Masszi, A.1
Di Ciano, C.2
Sirokmany, G.3
Arthur, W.T.4
Rotstein, O.D.5
Wang, J.6
McCulloch, C.A.G.7
Rosivall, L.8
Mucsi, I.9
Kapus, A.10
-
60
-
-
33646596637
-
Cooperation between snail and LEF-1 transcription factors is essential for TGF-beta1-induced epithelial-mesenchymal transition
-
Medici D, Hay ED, Goodenough DA. Cooperation between snail and LEF-1 transcription factors is essential for TGF-beta1-induced epithelial-mesenchymal transition. Mol Biol Cell 17: 1871-1879, 2006.
-
(2006)
Mol Biol Cell
, vol.17
, pp. 1871-1879
-
-
Medici, D.1
Hay, E.D.2
Goodenough, D.A.3
-
61
-
-
0028603343
-
TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: Involvement of type I receptors
-
Miettinen PJ, Ebner R, Lopez AR, Derynck R. TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors. J Cell Biol 127: 2021-2036, 1994.
-
(1994)
J Cell Biol
, vol.127
, pp. 2021-2036
-
-
Miettinen, P.J.1
Ebner, R.2
Lopez, A.R.3
Derynck, R.4
-
62
-
-
0035143413
-
Triggering the induction of myofibroblast and fibrogenesis by airway epithelial shedding
-
Morishima Y, Nomura A, Uchida Y, Noguchi Y, Sakamoto T, Ishii Y, Goto Y, Masuyama K, Zhang MJ, Hirano K, Mochizuki M, Ohtsuka M, Sekizawa K. Triggering the induction of myofibroblast and fibrogenesis by airway epithelial shedding. Am J Respir Cell Mol Biol 24: 1-11, 2001.
-
(2001)
Am J Respir Cell Mol Biol
, vol.24
, pp. 1-11
-
-
Morishima, Y.1
Nomura, A.2
Uchida, Y.3
Noguchi, Y.4
Sakamoto, T.5
Ishii, Y.6
Goto, Y.7
Masuyama, K.8
Zhang, M.J.9
Hirano, K.10
Mochizuki, M.11
Ohtsuka, M.12
Sekizawa, K.13
-
63
-
-
24944497786
-
Non-Smad TGF-beta signals
-
Moustakas A, Heldin CH. Non-Smad TGF-beta signals. J Cell Sci 118: 3573-3584, 2005.
-
(2005)
J Cell Sci
, vol.118
, pp. 3573-3584
-
-
Moustakas, A.1
Heldin, C.H.2
-
64
-
-
0027231698
-
Expression of tumour necrosis factor-alpha in cryptogenic fibrosing alveolitis
-
Nash JR, McLaughlin PJ, Butcher D, Corrin B. Expression of tumour necrosis factor-alpha in cryptogenic fibrosing alveolitis. Histopathology 22: 343-347, 1993.
-
(1993)
Histopathology
, vol.22
, pp. 343-347
-
-
Nash, J.R.1
McLaughlin, P.J.2
Butcher, D.3
Corrin, B.4
-
65
-
-
3342934231
-
Transforming growth factor beta (TGFβ) signalling in palatal growth, apoptosis and epithelial mesenchymal transformation (EMT)
-
Nawshad A, LaGamba D, Hay ED. Transforming growth factor beta (TGFβ) signalling in palatal growth, apoptosis and epithelial mesenchymal transformation (EMT). Arch Oral Biol 49: 675-689, 2004.
-
(2004)
Arch Oral Biol
, vol.49
, pp. 675-689
-
-
Nawshad, A.1
LaGamba, D.2
Hay, E.D.3
-
66
-
-
22144461325
-
Transforming growth factor-beta signaling during epithelial-mesenchymal transformation: Implications for embryogenesis and tumor metastasis
-
Nawshad A, Lagamba D, Polad A, Hay ED. Transforming growth factor-beta signaling during epithelial-mesenchymal transformation: implications for embryogenesis and tumor metastasis. Cells Tissues Organs 179: 11-23, 2005.
-
(2005)
Cells Tissues Organs
, vol.179
, pp. 11-23
-
-
Nawshad, A.1
Lagamba, D.2
Polad, A.3
Hay, E.D.4
-
67
-
-
0037474330
-
Epithelial to mesenchymal transition in Madin-Darby canine kidney cells is accompanied by down-regulation of Smad3 expression, leading to resistance to transforming growth factor-beta-induced growth arrest
-
Nicolas FJ, Lehmann K, Warne PH, Hill CS, Downward J. Epithelial to mesenchymal transition in Madin-Darby canine kidney cells is accompanied by down-regulation of Smad3 expression, leading to resistance to transforming growth factor-beta-induced growth arrest. J Biol Chem 278: 3251-3256, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 3251-3256
-
-
Nicolas, F.J.1
Lehmann, K.2
Warne, P.H.3
Hill, C.S.4
Downward, J.5
-
68
-
-
0029662049
-
TGFbeta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells
-
Oft M, Peli J, Rudaz C, Schwarz H, Beug H, Reichmann E. TGFbeta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells. Genes Dev 10: 2462-2477, 1996.
-
(1996)
Genes Dev
, vol.10
, pp. 2462-2477
-
-
Oft, M.1
Peli, J.2
Rudaz, C.3
Schwarz, H.4
Beug, H.5
Reichmann, E.6
-
69
-
-
0033865917
-
Progressive renal fibrosis in murine polycystic kidney disease: An immunohistochemical observation
-
Okada H, Ban S, Nagao S, Takahashi H, Suzuki H, Neilson EG. Progressive renal fibrosis in murine polycystic kidney disease: an immunohistochemical observation. Kidney Int 58: 587-597, 2000.
-
(2000)
Kidney Int
, vol.58
, pp. 587-597
-
-
Okada, H.1
Ban, S.2
Nagao, S.3
Takahashi, H.4
Suzuki, H.5
Neilson, E.G.6
-
70
-
-
0035661067
-
Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via the receptor for advanced glycation end products (RAGE)
-
Oldfield MD, Bach LA, Forbes JM, Nikolic-Paterson D, McRobert A, Thallas V, Atkins RC, Osicka T, Jerums G, Cooper ME. Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via the receptor for advanced glycation end products (RAGE). J Clin Invest 108: 1853-1863, 2001.
-
(2001)
J Clin Invest
, vol.108
, pp. 1853-1863
-
-
Oldfield, M.D.1
Bach, L.A.2
Forbes, J.M.3
Nikolic-Paterson, D.4
McRobert, A.5
Thallas, V.6
Atkins, R.C.7
Osicka, T.8
Jerums, G.9
Cooper, M.E.10
-
71
-
-
1642587815
-
Regulation of E-cadherin expression and beta-catenin/Tcf transcriptional activity by the integrin-linked kinase
-
Oloumi A, McPhee T, Dedhar S. Regulation of E-cadherin expression and beta-catenin/Tcf transcriptional activity by the integrin-linked kinase. Biochim Biophys Acta 1691: 1-15, 2004.
-
(2004)
Biochim Biophys Acta
, vol.1691
, pp. 1-15
-
-
Oloumi, A.1
McPhee, T.2
Dedhar, S.3
-
72
-
-
14844364701
-
Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity
-
Ozdamar B, Bose R, Barrios-Rodiles M, Wang HR, Zhang Y, Wrana JL. Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity. Science 307: 1603-1609, 2005.
-
(2005)
Science
, vol.307
, pp. 1603-1609
-
-
Ozdamar, B.1
Bose, R.2
Barrios-Rodiles, M.3
Wang, H.R.4
Zhang, Y.5
Wrana, J.L.6
-
73
-
-
0034883331
-
Type II alveolar epithelial cells and interstitial fibroblasts express connective tissue growth factor in IPF
-
Pan L, Yamauchi K, Uzuki M, Nakanishi T, Takigawa M, Inoue H, Sawai T. Type II alveolar epithelial cells and interstitial fibroblasts express connective tissue growth factor in IPF. Eur Respir J 17: 1220-1227, 2001.
-
(2001)
Eur Respir J
, vol.17
, pp. 1220-1227
-
-
Pan, L.1
Yamauchi, K.2
Uzuki, M.3
Nakanishi, T.4
Takigawa, M.5
Inoue, H.6
Sawai, T.7
-
74
-
-
0031918551
-
Bronchiolitis obliterans: Pathogenesis, prevention, management
-
Paradis I. Bronchiolitis obliterans: pathogenesis, prevention, management. Am J Med Sci 315: 161-178, 1998.
-
(1998)
Am J Med Sci
, vol.315
, pp. 161-178
-
-
Paradis, I.1
-
75
-
-
33744938426
-
Matrix metalloproteases in aberrant fibrotic tissue remodeling
-
Pardo A, Selman M. Matrix metalloproteases in aberrant fibrotic tissue remodeling. Proc Am Thorac Soc 3: 383-388, 2006.
-
(2006)
Proc Am Thorac Soc
, vol.3
, pp. 383-388
-
-
Pardo, A.1
Selman, M.2
-
76
-
-
0038756636
-
Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: Mechanisms for epithelial mesenchymal transitions
-
Peinado H, Quintanilla M, Cano A. Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions. J Biol Chem 278: 21113-21123, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 21113-21123
-
-
Peinado, H.1
Quintanilla, M.2
Cano, A.3
-
77
-
-
30744478450
-
The differential role of Smad2 and Smad3 in the regulation of pro-fibrotic TGFβ1 responses in human proximal-tubule epithelial cells
-
Phanish MK, Wahab NA, Colville-Nash P, Hendry BM, Dockrell ME. The differential role of Smad2 and Smad3 in the regulation of pro-fibrotic TGFβ1 responses in human proximal-tubule epithelial cells. Biochem J 393: 601-607, 2006.
-
(2006)
Biochem J
, vol.393
, pp. 601-607
-
-
Phanish, M.K.1
Wahab, N.A.2
Colville-Nash, P.3
Hendry, B.M.4
Dockrell, M.E.5
-
78
-
-
0033377867
-
TGF-(beta) type I receptor/ALK-5 and Smad proteins mediate epithelial to mesenchymal transdifferentiation in NMuMG breast epithelial cells
-
Piek E, Moustakas A, Kurisaki A, Heldin CH, ten Dijke P. TGF-(beta) type I receptor/ALK-5 and Smad proteins mediate epithelial to mesenchymal transdifferentiation in NMuMG breast epithelial cells. J Cell Sci 112: 4557-4568, 1999.
-
(1999)
J Cell Sci
, vol.112
, pp. 4557-4568
-
-
Piek, E.1
Moustakas, A.2
Kurisaki, A.3
Heldin, C.H.4
ten Dijke, P.5
-
79
-
-
21844432918
-
Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability
-
Radisky DC, Levy DD, Littlepage LE, Liu H, Nelson CM, Fata JE, Leake D, Godden EL, Albertson DG, Nieto MA, Werb Z, Bissell MJ. Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability. Nature 436: 123-127, 2005.
-
(2005)
Nature
, vol.436
, pp. 123-127
-
-
Radisky, D.C.1
Levy, D.D.2
Littlepage, L.E.3
Liu, H.4
Nelson, C.M.5
Fata, J.E.6
Leake, D.7
Godden, E.L.8
Albertson, D.G.9
Nieto, M.A.10
Werb, Z.11
Bissell, M.J.12
-
80
-
-
0036318317
-
Epithelial-mesenchymal transition of tubular epithelial cells in human renal biopsies
-
Rastaldi MP, Ferrario F, Giardino L, Dell'Antonio G, Grillo C, Grillo P, Strutz F, Muller GA, Colasanti G, D'Amico G. Epithelial-mesenchymal transition of tubular epithelial cells in human renal biopsies. Kidney Int 62: 137-146, 2002.
-
(2002)
Kidney Int
, vol.62
, pp. 137-146
-
-
Rastaldi, M.P.1
Ferrario, F.2
Giardino, L.3
Dell'Antonio, G.4
Grillo, C.5
Grillo, P.6
Strutz, F.7
Muller, G.A.8
Colasanti, G.9
D'Amico, G.10
-
81
-
-
20544437490
-
Role of reactive oxygen species in TGF-beta1-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells
-
Rhyu DY, Yang Y, Ha H, Lee GT, Song JS, Uh ST, Lee HB. Role of reactive oxygen species in TGF-beta1-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells. J Am Soc Nephrol 16: 667-675, 2005.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 667-675
-
-
Rhyu, D.Y.1
Yang, Y.2
Ha, H.3
Lee, G.T.4
Song, J.S.5
Uh, S.T.6
Lee, H.B.7
-
82
-
-
0024505353
-
Subepithelial fibrosis in the bronchi of asthmatics
-
Roche WR, Beasley R, Williams JH, Holgate ST. Subepithelial fibrosis in the bronchi of asthmatics. Lancet 1: 520-524, 1989.
-
(1989)
Lancet
, vol.1
, pp. 520-524
-
-
Roche, W.R.1
Beasley, R.2
Williams, J.H.3
Holgate, S.T.4
-
83
-
-
0020584332
-
Granular pneumocytes in primary culture secrete several major components of the extracellular matrix
-
Sage H, Farin FM, Striker GE, Fisher AB. Granular pneumocytes in primary culture secrete several major components of the extracellular matrix. Biochemistry 22: 2148-2155, 1983.
-
(1983)
Biochemistry
, vol.22
, pp. 2148-2155
-
-
Sage, H.1
Farin, F.M.2
Striker, G.E.3
Fisher, A.B.4
-
84
-
-
33644831172
-
Adenoviral gene transfer of BMP-7, Id2, or Id3 suppresses injury-induced epithelial-to-mesenchymal transition of lens epithelium in mice
-
Saika S, Ikeda K, Yamanaka O, Flanders KC, Ohnishi Y, Nakajima Y, Muragaki Y, Ooshima A. Adenoviral gene transfer of BMP-7, Id2, or Id3 suppresses injury-induced epithelial-to-mesenchymal transition of lens epithelium in mice. Am J Physiol Cell Physiol 290: C282-C289, 2006.
-
(2006)
Am J Physiol Cell Physiol
, vol.290
-
-
Saika, S.1
Ikeda, K.2
Yamanaka, O.3
Flanders, K.C.4
Ohnishi, Y.5
Nakajima, Y.6
Muragaki, Y.7
Ooshima, A.8
-
85
-
-
1542289674
-
Smad3 signaling is required for epithelial-mesenchymal transition of lens epithelium after injury
-
Saika S, Kono-Saika S, Ohnishi Y, Sato M, Muragaki Y, Ooshima A, Flanders KC, Yoo J, Anzano M, Liu CY, Kao WW, Roberts AB. Smad3 signaling is required for epithelial-mesenchymal transition of lens epithelium after injury. Am J Pathol 164: 651-663, 2004.
-
(2004)
Am J Pathol
, vol.164
, pp. 651-663
-
-
Saika, S.1
Kono-Saika, S.2
Ohnishi, Y.3
Sato, M.4
Muragaki, Y.5
Ooshima, A.6
Flanders, K.C.7
Yoo, J.8
Anzano, M.9
Liu, C.Y.10
Kao, W.W.11
Roberts, A.B.12
-
86
-
-
33748776858
-
JNK mediates TGF-β1-induced epithelial mesenchymal transdifferentiation of mouse transformed keratinocytes
-
Santibanez JF. JNK mediates TGF-β1-induced epithelial mesenchymal transdifferentiation of mouse transformed keratinocytes. FEBS Lett 580: 5385-5391, 2006.
-
(2006)
FEBS Lett
, vol.580
, pp. 5385-5391
-
-
Santibanez, J.F.1
-
87
-
-
0346727324
-
Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubuloin-terstitial fibrosis induced by unilateral ureteral obstruction
-
Sato M, Muragaki Y, Saika S, Roberts AB, Ooshima A. Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubuloin-terstitial fibrosis induced by unilateral ureteral obstruction. J Clin Invest 112: 1486-1494, 2003.
-
(2003)
J Clin Invest
, vol.112
, pp. 1486-1494
-
-
Sato, M.1
Muragaki, Y.2
Saika, S.3
Roberts, A.B.4
Ooshima, A.5
-
88
-
-
0041827226
-
The epithelial/fibroblastic pathway in the pathogenesis of idiopathic pulmonary fibrosis
-
Selman M, Pardo A. The epithelial/fibroblastic pathway in the pathogenesis of idiopathic pulmonary fibrosis. Am J Respir Cell Mol Biol 29: S93-S96, 2003.
-
(2003)
Am J Respir Cell Mol Biol
, vol.29
-
-
Selman, M.1
Pardo, A.2
-
89
-
-
0033830350
-
TIMP-1, -2, -3, and -4 in idiopathic pulmonary fibrosis. A prevailing nondegradative lung microenvironment?
-
Selman M, Ruiz V, Cabrera S, Segura L, Ramirez R, Barrios R, Pardo A. TIMP-1, -2, -3, and -4 in idiopathic pulmonary fibrosis. A prevailing nondegradative lung microenvironment? Am J Physiol Lung Cell Mol Physiol 279: L562-L574, 2000.
-
(2000)
Am J Physiol Lung Cell Mol Physiol
, vol.279
-
-
Selman, M.1
Ruiz, V.2
Cabrera, S.3
Segura, L.4
Ramirez, R.5
Barrios, R.6
Pardo, A.7
-
90
-
-
1542411333
-
Idiopathic pulmonary fibrosis: Pathogenesis and therapeutic approaches
-
Selman M, Thannickal V, Pardo A, Zisman DA, Martinez FJ, Lynch JP. Idiopathic pulmonary fibrosis: pathogenesis and therapeutic approaches. Drugs 64: 405-430, 2004.
-
(2004)
Drugs
, vol.64
, pp. 405-430
-
-
Selman, M.1
Thannickal, V.2
Pardo, A.3
Zisman, D.A.4
Martinez, F.J.5
Lynch, J.P.6
-
91
-
-
0033178473
-
Mechanisms of myofibroblast activity and phenotypic modulation
-
Serini G, Gabbiani G. Mechanisms of myofibroblast activity and phenotypic modulation. Exp Cell Res 250: 273-283, 1999.
-
(1999)
Exp Cell Res
, vol.250
, pp. 273-283
-
-
Serini, G.1
Gabbiani, G.2
-
92
-
-
0035020567
-
Fibrosis of the lung and other tissues: New concepts in pathogenesis and treatment
-
Sime PJ, O'Reilly KMA. Fibrosis of the lung and other tissues: new concepts in pathogenesis and treatment. Clin Immunol 99: 308-319, 2001.
-
(2001)
Clin Immunol
, vol.99
, pp. 308-319
-
-
Sime, P.J.1
O'Reilly, K.M.A.2
-
93
-
-
0035479834
-
Transdifferentiation and metaplasia-switching cell types
-
Slack JM, Tosh D. Transdifferentiation and metaplasia-switching cell types. Curr Opin Genet Dev 11: 581-586, 2001.
-
(2001)
Curr Opin Genet Dev
, vol.11
, pp. 581-586
-
-
Slack, J.M.1
Tosh, D.2
-
94
-
-
0029091682
-
Identification and characterization of a fibroblast marker: FSP1
-
Strutz F, Okada H, Lo CW, Danoff T, Carone RL, Tomaszewski JE, Neilson EG. Identification and characterization of a fibroblast marker: FSP1. J Cell Biol 130: 393-405, 1995.
-
(1995)
J Cell Biol
, vol.130
, pp. 393-405
-
-
Strutz, F.1
Okada, H.2
Lo, C.W.3
Danoff, T.4
Carone, R.L.5
Tomaszewski, J.E.6
Neilson, E.G.7
-
95
-
-
0036595629
-
Epithelial-mesenchymal transitions in tumour progression
-
Thiery JP. Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2: 442-454, 2002.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 442-454
-
-
Thiery, J.P.1
-
96
-
-
33746034613
-
Transforming growth factor-beta employs HMGA2 to elicit epithelial-mesenchymal transition
-
Thuault S, Valcourt U, Petersen M, Manfioletti G, Heldin CH, Moustakas A. Transforming growth factor-beta employs HMGA2 to elicit epithelial-mesenchymal transition. J Cell Biol 174: 175-183, 2006.
-
(2006)
J Cell Biol
, vol.174
, pp. 175-183
-
-
Thuault, S.1
Valcourt, U.2
Petersen, M.3
Manfioletti, G.4
Heldin, C.H.5
Moustakas, A.6
-
97
-
-
3042738106
-
Smad-binding defective mutant of transforming growth factor beta type I receptor enhances tumorigenesis but suppresses metastasis of breast cancer cell lines
-
Tian F, Byfield SD, Parks WT, Stuelten CH, Nemani D, Zhang YE, Roberts AB. Smad-binding defective mutant of transforming growth factor beta type I receptor enhances tumorigenesis but suppresses metastasis of breast cancer cell lines. Cancer Res 64: 4523-4530, 2004.
-
(2004)
Cancer Res
, vol.64
, pp. 4523-4530
-
-
Tian, F.1
Byfield, S.D.2
Parks, W.T.3
Stuelten, C.H.4
Nemani, D.5
Zhang, Y.E.6
Roberts, A.B.7
-
98
-
-
0347626102
-
Reduction in Smad2/3 signaling enhances tumorigenesis but suppresses metastasis of breast cancer cell lines
-
Tian F, DaCosta Byfield S, Parks WT, Yoo S, Felici A, Tang B, Piek E, Wakefield LM, Roberts AB. Reduction in Smad2/3 signaling enhances tumorigenesis but suppresses metastasis of breast cancer cell lines. Cancer Res 63: 8284-8292, 2003.
-
(2003)
Cancer Res
, vol.63
, pp. 8284-8292
-
-
Tian, F.1
DaCosta Byfield, S.2
Parks, W.T.3
Yoo, S.4
Felici, A.5
Tang, B.6
Piek, E.7
Wakefield, L.M.8
Roberts, A.B.9
-
99
-
-
0037080547
-
American Thoracic Society/European Respiratory Society International Multidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias
-
Travis WD, King TE Jr, Bateman ED, Lynch DA. American Thoracic Society/European Respiratory Society International Multidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias. Am J Respir Crit Care Med 265: 277-304, 2002.
-
(2002)
Am J Respir Crit Care Med
, vol.265
, pp. 277-304
-
-
Travis, W.D.1
King Jr, T.E.2
Bateman, E.D.3
Lynch, D.A.4
-
100
-
-
0032437815
-
Alveolar epithelial cell death adjacent to underlying myofibroblasts in advanced fibrotic human lung
-
Uhal BD, Joshi I, Hughes WF, Ramos C, Pardo A, Selman M. Alveolar epithelial cell death adjacent to underlying myofibroblasts in advanced fibrotic human lung. Am J Physiol Lung Cell Mol Physiol 275: L1192-L1199, 1998.
-
(1998)
Am J Physiol Lung Cell Mol Physiol
, vol.275
-
-
Uhal, B.D.1
Joshi, I.2
Hughes, W.F.3
Ramos, C.4
Pardo, A.5
Selman, M.6
-
101
-
-
16344378397
-
TGF-beta and the Smad signaling pathway support transcriptomic reprogramming during epithelial-mesenchymal cell transition
-
Valcourt U, Kowanetz M, Niimi H, Heldin CH, Moustakas A. TGF-beta and the Smad signaling pathway support transcriptomic reprogramming during epithelial-mesenchymal cell transition. Mol Biol Cell 16: 1987-2002, 2005.
-
(2005)
Mol Biol Cell
, vol.16
, pp. 1987-2002
-
-
Valcourt, U.1
Kowanetz, M.2
Niimi, H.3
Heldin, C.H.4
Moustakas, A.5
-
102
-
-
0030428267
-
E-cadherin transforms embryonic corneal fibroblasts to stratified epithelium with desmosomes
-
Vanderburg CR, Hay ED. E-cadherin transforms embryonic corneal fibroblasts to stratified epithelium with desmosomes. Acta Anat 157: 87-104, 1996.
-
(1996)
Acta Anat
, vol.157
, pp. 87-104
-
-
Vanderburg, C.R.1
Hay, E.D.2
-
103
-
-
26944463075
-
Phenotype of airway epithelial cells suggests epithelial to mesenchymal cell transition in clinically stable lung transplant recipients
-
Ward C, Forrest IA, Murphy DM, Johnson GE, Robertson H, Cawston TE, Fisher AJ, Dark JH, Lordan JL, Kirby JA, Corris PA. Phenotype of airway epithelial cells suggests epithelial to mesenchymal cell transition in clinically stable lung transplant recipients. Thorax 60: 865-871, 2005.
-
(2005)
Thorax
, vol.60
, pp. 865-871
-
-
Ward, C.1
Forrest, I.A.2
Murphy, D.M.3
Johnson, G.E.4
Robertson, H.5
Cawston, T.E.6
Fisher, A.J.7
Dark, J.H.8
Lordan, J.L.9
Kirby, J.A.10
Corris, P.A.11
-
104
-
-
33744944779
-
Epithelial origin of myofibroblasts during fibrosis in the lung
-
Willis BC, duBois RM, Borok Z. Epithelial origin of myofibroblasts during fibrosis in the lung. Proc Am Thorac Soc 3: 377-382, 2006.
-
(2006)
Proc Am Thorac Soc
, vol.3
, pp. 377-382
-
-
Willis, B.C.1
duBois, R.M.2
Borok, Z.3
-
105
-
-
17844384822
-
Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: Potential role in idiopathic pulmonary fibrosis
-
Willis BC, Liebler JM, Luby-Phelps K, Nicholson AG, Crandall ED, du Bois RM, Borok Z. Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis. Am J Pathol 166: 1321-1332, 2005.
-
(2005)
Am J Pathol
, vol.166
, pp. 1321-1332
-
-
Willis, B.C.1
Liebler, J.M.2
Luby-Phelps, K.3
Nicholson, A.G.4
Crandall, E.D.5
du Bois, R.M.6
Borok, Z.7
-
106
-
-
0642306119
-
Transforming growth factor beta-regulated gene expression in a mouse mammary gland epithelial cell line
-
Xie L, Law BK, Aakre ME, Edgerton M, Shyr Y, Bhowmick NA, Moses HL. Transforming growth factor beta-regulated gene expression in a mouse mammary gland epithelial cell line. Breast Cancer Res 5: R187-R198, 2003.
-
(2003)
Breast Cancer Res
, vol.5
-
-
Xie, L.1
Law, B.K.2
Aakre, M.E.3
Edgerton, M.4
Shyr, Y.5
Bhowmick, N.A.6
Moses, H.L.7
-
107
-
-
6944248910
-
Activation of the Erk pathway is required for TGF-beta1-induced EMT in vitro
-
Xie L, Law BK, Chytil AM, Brown KA, Aakre ME, Moses HL. Activation of the Erk pathway is required for TGF-beta1-induced EMT in vitro. Neoplasia 6: 603-610, 2004.
-
(2004)
Neoplasia
, vol.6
, pp. 603-610
-
-
Xie, L.1
Law, B.K.2
Chytil, A.M.3
Brown, K.A.4
Aakre, M.E.5
Moses, H.L.6
-
108
-
-
0041677660
-
Release of biologically active TGF-β1 by alveolar epithelial cells results in pulmonary fibrosis
-
Xu YD, Hua J, Mui A, O'Connor R, Grotendorst G, Khalil N. Release of biologically active TGF-β1 by alveolar epithelial cells results in pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol 285: L527-L539, 2003.
-
(2003)
Am J Physiol Lung Cell Mol Physiol
, vol.285
-
-
Xu, Y.D.1
Hua, J.2
Mui, A.3
O'Connor, R.4
Grotendorst, G.5
Khalil, N.6
-
109
-
-
16844371760
-
A novel mechanism by which hepatocyte growth factor blocks tubular epithelial to mesenchymal transition
-
Yang J, Dai C, Liu Y. A novel mechanism by which hepatocyte growth factor blocks tubular epithelial to mesenchymal transition. J Am Soc Nephrol 16: 68-78, 2005.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 68-78
-
-
Yang, J.1
Dai, C.2
Liu, Y.3
-
110
-
-
6344254484
-
TGF-β1 induces alveolar epithelial to mesenchymal transition in vitro
-
Yao HW, Xie QM, Chen JQ, Deng YM, Tang HF. TGF-β1 induces alveolar epithelial to mesenchymal transition in vitro. Life Sci 76: 29-37, 2004.
-
(2004)
Life Sci
, vol.76
, pp. 29-37
-
-
Yao, H.W.1
Xie, Q.M.2
Chen, J.Q.3
Deng, Y.M.4
Tang, H.F.5
-
111
-
-
33947171101
-
Insulin-like growth factor-binding protein-5 induces pulmonary fibrosis and triggers mononuclear cellular infiltration
-
Yasuoka H, Zhou Z, Pilewski JM, Oury TD, Choi AM, Feghali-Bostwick CA. Insulin-like growth factor-binding protein-5 induces pulmonary fibrosis and triggers mononuclear cellular infiltration. Am J Pathol 169: 1633-1642, 2006.
-
(2006)
Am J Pathol
, vol.169
, pp. 1633-1642
-
-
Yasuoka, H.1
Zhou, Z.2
Pilewski, J.M.3
Oury, T.D.4
Choi, A.M.5
Feghali-Bostwick, C.A.6
-
112
-
-
0037099745
-
TGF-β receptor-activated p38 MAP kinase mediates Smad-independent TGF-β responses
-
Yu L, Hebert MC, Zhang YE. TGF-β receptor-activated p38 MAP kinase mediates Smad-independent TGF-β responses. EMBO J 21: 3749-3759, 2002.
-
(2002)
EMBO J
, vol.21
, pp. 3749-3759
-
-
Yu, L.1
Hebert, M.C.2
Zhang, Y.E.3
-
113
-
-
0035810944
-
Genetic programs of epithelial cell plasticity directed by transforming growth factor-beta
-
Zavadil J, Bitzer M, Liang D, Yang YC, Massimi A, Kneitz S, Piek E, Bottinger EP. Genetic programs of epithelial cell plasticity directed by transforming growth factor-beta. Proc Natl Acad Sci USA 98: 6686-6691, 2001.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 6686-6691
-
-
Zavadil, J.1
Bitzer, M.2
Liang, D.3
Yang, Y.C.4
Massimi, A.5
Kneitz, S.6
Piek, E.7
Bottinger, E.P.8
-
114
-
-
24644487312
-
TGF-β and epithelial-to-mesenchymal transitions
-
Zavadil J, Bottinger EP. TGF-β and epithelial-to-mesenchymal transitions. Oncogene 24: 5764-5774, 2005.
-
(2005)
Oncogene
, vol.24
, pp. 5764-5774
-
-
Zavadil, J.1
Bottinger, E.P.2
-
115
-
-
1842524153
-
Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition
-
Zavadil J, Cermak L, Soto-Nieves N, Bottinger EP. Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition. EMBO J 23: 1155-1165, 2004.
-
(2004)
EMBO J
, vol.23
, pp. 1155-1165
-
-
Zavadil, J.1
Cermak, L.2
Soto-Nieves, N.3
Bottinger, E.P.4
-
116
-
-
0038717407
-
BMP-7 counteracts TGF-β1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury
-
Zeisberg M, Hanai Ji Sugimoto H, Mammoto T, Charytan D, Strutz F, Kalluri R. BMP-7 counteracts TGF-β1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury. Nat Med 9: 964-968, 2003.
-
(2003)
Nat Med
, vol.9
, pp. 964-968
-
-
Zeisberg, M.1
Hanai, J.2
Sugimoto, H.3
Mammoto, T.4
Charytan, D.5
Strutz, F.6
Kalluri, R.7
-
117
-
-
1642379154
-
The role of epithelial-to-mesenchymal transition in renal fibrosis
-
Zeisberg M, Kalluri R. The role of epithelial-to-mesenchymal transition in renal fibrosis. J Mol Med 82: 175-181, 2004.
-
(2004)
J Mol Med
, vol.82
, pp. 175-181
-
-
Zeisberg, M.1
Kalluri, R.2
-
118
-
-
14844290237
-
Bone morphogenic protein-7 induces mesenchymal to epithelial transition in adult renal fibroblasts and facilitates regeneration of injured kidney
-
Zeisberg M, Shah AA, Kalluri R. Bone morphogenic protein-7 induces mesenchymal to epithelial transition in adult renal fibroblasts and facilitates regeneration of injured kidney. J Biol Chem 280: 8094-8100, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 8094-8100
-
-
Zeisberg, M.1
Shah, A.A.2
Kalluri, R.3
-
119
-
-
0036086293
-
Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice
-
Zhao J, Shi W, Wang YL, Chen H, Bringas P Jr, Datto MB, Frederick JP, Wang XF, Warburton D. Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice. Am J Physiol Lung Cell Mol Physiol 282: L585-L593, 2002.
-
(2002)
Am J Physiol Lung Cell Mol Physiol
, vol.282
-
-
Zhao, J.1
Shi, W.2
Wang, Y.L.3
Chen, H.4
Bringas Jr, P.5
Datto, M.B.6
Frederick, J.P.7
Wang, X.F.8
Warburton, D.9
-
120
-
-
0034658674
-
Oncogenic ras downregulates rac activity, which leads to increased rho activity and epithelial-mesenchymal transition
-
Zondag GCM, Evers EE, ten Klooster JP, Janssen L, van der Kammen RA, Collard JG. Oncogenic ras downregulates rac activity, which leads to increased rho activity and epithelial-mesenchymal transition. J Cell Biol 149: 775-781, 2000.
-
(2000)
J Cell Biol
, vol.149
, pp. 775-781
-
-
Zondag, G.C.M.1
Evers, E.E.2
ten Klooster, J.P.3
Janssen, L.4
van der Kammen, R.A.5
Collard, J.G.6
-
121
-
-
0028670258
-
Expression of beta 1 integrins changes during transformation of avian lens epithelium to mesenchyme in collagen gels
-
Zuk A, Hay ED. Expression of beta 1 integrins changes during transformation of avian lens epithelium to mesenchyme in collagen gels. Dev Dyn 201: 378-393, 1994.
-
(1994)
Dev Dyn
, vol.201
, pp. 378-393
-
-
Zuk, A.1
Hay, E.D.2
-
122
-
-
18344396051
-
Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans
-
Zuo F, Kaminski N, Eugui E, Allard J, Yakhini Z, Ben-Dor A, Lollini L, Morris D, Kim Y, DeLustro B, Sheppard D, Pardo A, Selman M, Heller RA. Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans. Proc Natl Acad Sci USA 99: 6292-6297, 2002.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 6292-6297
-
-
Zuo, F.1
Kaminski, N.2
Eugui, E.3
Allard, J.4
Yakhini, Z.5
Ben-Dor, A.6
Lollini, L.7
Morris, D.8
Kim, Y.9
DeLustro, B.10
Sheppard, D.11
Pardo, A.12
Selman, M.13
Heller, R.A.14
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