메뉴 건너뛰기




Volumn 43, Issue 3, 2006, Pages 435-443

Phagocytosis of apoptotic bodies by hepatic stellate cells induces NADPH oxidase and is associated with liver fibrosis in vivo

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE PROTEIN; PROCOLLAGEN; PROCOLLAGEN ALPHA1; PROTEIN P47PHOX; PROTEIN SUBUNIT; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

EID: 33645243410     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.21093     Document Type: Article
Times cited : (254)

References (47)
  • 1
    • 0034767501 scopus 로고    scopus 로고
    • Transforming growth factor beta and the liver
    • Bissell DM, Roulot D, George J. Transforming growth factor beta and the liver. HEPATOLOGY 2001;34:859-867.
    • (2001) Hepatology , vol.34 , pp. 859-867
    • Bissell, D.M.1    Roulot, D.2    George, J.3
  • 2
    • 12044260143 scopus 로고
    • Seminars in medicine of the Beth Israel Hospital, Boston. The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies
    • Friedman SL. Seminars in medicine of the Beth Israel Hospital, Boston. The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies. N Engl J Med 1993;328:1828-1935.
    • (1993) N Engl J Med , vol.328 , pp. 1828-1935
    • Friedman, S.L.1
  • 3
    • 0034808310 scopus 로고    scopus 로고
    • History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cells
    • Geerts A. History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cells. Semin Liver Dis 2001;21:311-335.
    • (2001) Semin Liver Dis , vol.21 , pp. 311-335
    • Geerts, A.1
  • 4
    • 0034809664 scopus 로고    scopus 로고
    • Interactions between hepatic stellate cells and the immune system
    • Maher JJ. Interactions between hepatic stellate cells and the immune system. Semin Liver Dis 2001;21:417-426.
    • (2001) Semin Liver Dis , vol.21 , pp. 417-426
    • Maher, J.J.1
  • 5
    • 0025821563 scopus 로고
    • Modulation of alpha smooth muscle actin and desmin expression in perisinusoidal cells of normal and diseased human livers
    • Schmitt-Graff A, Kruger S, Bochard F, Gabbiani G, Denk H. Modulation of alpha smooth muscle actin and desmin expression in perisinusoidal cells of normal and diseased human livers. Am J Pathol 1991;138:1233-1242.
    • (1991) Am J Pathol , vol.138 , pp. 1233-1242
    • Schmitt-Graff, A.1    Kruger, S.2    Bochard, F.3    Gabbiani, G.4    Denk, H.5
  • 6
    • 0033607304 scopus 로고    scopus 로고
    • In vivo inhibition of rat stellate cell activation by soluble transforming growth factor beta type II receptor: A potential new therapy for hepatic fibrosis
    • George J, Roulot D, Koteliansky VE, Bissell DM. In vivo inhibition of rat stellate cell activation by soluble transforming growth factor beta type II receptor: a potential new therapy for hepatic fibrosis. Proc Natl Acad Sci U S A 1999;96:12719-12724.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 12719-12724
    • George, J.1    Roulot, D.2    Koteliansky, V.E.3    Bissell, D.M.4
  • 7
    • 0035958625 scopus 로고    scopus 로고
    • Transforming growth factor beta signal transduction in hepatic stellate cells via Smad2/3 phosphorylation, a pathway that is abrogated during in vitro progression to myofibroblasts. TGFbeta signal transduction during transdifferentiation of hepatic stellate cells
    • Dooley S, Delvoux B, Streckert M, Bonzel L, Stopa M, ten Dijke P, et al. Transforming growth factor beta signal transduction in hepatic stellate cells via Smad2/3 phosphorylation, a pathway that is abrogated during in vitro progression to myofibroblasts. TGFbeta signal transduction during transdifferentiation of hepatic stellate cells. FEBS Lett 2001;502:4-10.
    • (2001) FEBS Lett , vol.502 , pp. 4-10
    • Dooley, S.1    Delvoux, B.2    Streckert, M.3    Bonzel, L.4    Stopa, M.5    Ten Dijke, P.6
  • 8
    • 0032519925 scopus 로고    scopus 로고
    • Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF
    • Fadok VA, Bratton DL, Konowal A, Freed PW, Westcott JY, Henson PM. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. J Clin Invest 1998;101:890-898.
    • (1998) J Clin Invest , vol.101 , pp. 890-898
    • Fadok, V.A.1    Bratton, D.L.2    Konowal, A.3    Freed, P.W.4    Westcott, J.Y.5    Henson, P.M.6
  • 10
    • 0037115158 scopus 로고    scopus 로고
    • Reactive oxygen species and cell signaling: Respiratory burst in macrophage signaling
    • Forman HJ, Torres M. Reactive oxygen species and cell signaling: respiratory burst in macrophage signaling. Am J Respir Crit Care Med 2002;166:S4-S8.
    • (2002) Am J Respir Crit Care Med , vol.166
    • Forman, H.J.1    Torres, M.2
  • 11
    • 0025904386 scopus 로고
    • Identification of a superoxide-generating NADPH oxidase system in human fibroblasts
    • Meier B, Cross AR, Hancock JT, Kaup FJ, Jones OT. Identification of a superoxide-generating NADPH oxidase system in human fibroblasts. Biochem J 1991;275:241-245.
    • (1991) Biochem J , vol.275 , pp. 241-245
    • Meier, B.1    Cross, A.R.2    Hancock, J.T.3    Kaup, F.J.4    Jones, O.T.5
  • 12
    • 0347711117 scopus 로고    scopus 로고
    • NADPH oxidases: Not just for leukocytes anymore!
    • Bokoch GM, Knaus UG. NADPH oxidases: not just for leukocytes anymore! Trends Biochem Sci 2003;28:502-508.
    • (2003) Trends Biochem Sci , vol.28 , pp. 502-508
    • Bokoch, G.M.1    Knaus, U.G.2
  • 13
    • 0031574128 scopus 로고    scopus 로고
    • The NADPH oxidase of phagocytic leukocytes
    • Segal AW, Shatwell KP. The NADPH oxidase of phagocytic leukocytes. Ann N Y Acad Sci 1997;832:215-222.
    • (1997) Ann N Y Acad Sci , vol.832 , pp. 215-222
    • Segal, A.W.1    Shatwell, K.P.2
  • 14
    • 0035178542 scopus 로고    scopus 로고
    • Signaling by the respiratory burst in macrophages
    • Forman HJ, Torres M. Signaling by the respiratory burst in macrophages. IUBMB Life 2001;51:365-371.
    • (2001) IUBMB Life , vol.51 , pp. 365-371
    • Forman, H.J.1    Torres, M.2
  • 16
  • 19
    • 10844242987 scopus 로고    scopus 로고
    • Human hepatic stellate cell lines, LX-1 and LX-2: New tools for analysis of hepatic fibrosis
    • Xu L, Hui AY, Albanis E, Arthur MJ, O'Byrne SM, Blaner WS, et al. Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis. Gut 2005;54:142-151.
    • (2005) Gut , vol.54 , pp. 142-151
    • Xu, L.1    Hui, A.Y.2    Albanis, E.3    Arthur, M.J.4    O'Byrne, S.M.5    Blaner, W.S.6
  • 20
    • 0015153416 scopus 로고
    • Superoxide dismutase: Improved assays and an assay applicable to acrylamide gels
    • Beauchamp C, Fridovich I. Superoxide dismutase: improved assays and an assay applicable to acrylamide gels. Anal Biochem 1971;44:276-287.
    • (1971) Anal Biochem , vol.44 , pp. 276-287
    • Beauchamp, C.1    Fridovich, I.2
  • 21
    • 14744272123 scopus 로고    scopus 로고
    • 3D molecular modeling, free radical modulating and immune cells signaling activities of the novel peptidomimetic 1-glutamyl-histamine: Possible immunostimulating role
    • Babizhayev MA, Semiletov YA, Lul'kin YA, Sakina NL, Savel'yeva EL, Alimbarova LM, et al. 3D molecular modeling, free radical modulating and immune cells signaling activities of the novel peptidomimetic 1-glutamyl-histamine: possible immunostimulating role. Peptides 2005;26:551-563.
    • (2005) Peptides , vol.26 , pp. 551-563
    • Babizhayev, M.A.1    Semiletov, Y.A.2    Lul'kin, Y.A.3    Sakina, N.L.4    Savel'yeva, E.L.5    Alimbarova, L.M.6
  • 22
    • 0001166951 scopus 로고
    • A formaldehyde-glutaraldehyde fixative of high osmolarity for use in electron microscopy
    • Karnovsky. A formaldehyde-glutaraldehyde fixative of high osmolarity for use in electron microscopy. J Cell Biol 1965;27:137A.
    • (1965) J Cell Biol , vol.27
    • Karnovsky1
  • 23
  • 24
    • 0034438299 scopus 로고    scopus 로고
    • Appearance of denuded hepatic stellate cells and their subsequent myofibroblast-like transformarion during the early stage of biliary fibrosis in the rat
    • Tao LH, Enzan H, Hayashi Y, Miyazaki E, Saibara T, Hiroi M, et al. Appearance of denuded hepatic stellate cells and their subsequent myofibroblast-like transformarion during the early stage of biliary fibrosis in the rat. Med Electron Microsc 2000;33:217-230.
    • (2000) Med Electron Microsc , vol.33 , pp. 217-230
    • Tao, L.H.1    Enzan, H.2    Hayashi, Y.3    Miyazaki, E.4    Saibara, T.5    Hiroi, M.6
  • 25
    • 0038082099 scopus 로고    scopus 로고
    • Hepatic stellate cells: Unique characteristics in cell biology and phenotype
    • Sato M, Suzuki S, Senoo H. Hepatic stellate cells: unique characteristics in cell biology and phenotype. Cell Struct Funct 2003;28:105-112.
    • (2003) Cell Struct Funct , vol.28 , pp. 105-112
    • Sato, M.1    Suzuki, S.2    Senoo, H.3
  • 26
    • 0842301109 scopus 로고    scopus 로고
    • Structure and function of hepatic stellate cells
    • Senoo H. Structure and function of hepatic stellate cells. Med Electron Microsc 2004;37:3-15.
    • (2004) Med Electron Microsc , vol.37 , pp. 3-15
    • Senoo, H.1
  • 27
    • 0345015494 scopus 로고    scopus 로고
    • Mechanisms of internalization of apoptotic and necrotic L929 cells by a macrophage cell line studied by electron microscopy
    • Krysko DV, Brouckaert G, Kalai M, Vandenabeele P, D'Herde K. Mechanisms of internalization of apoptotic and necrotic L929 cells by a macrophage cell line studied by electron microscopy. J Morphol 2003;258:336-345
    • (2003) J Morphol , vol.258 , pp. 336-345
    • Krysko, D.V.1    Brouckaert, G.2    Kalai, M.3    Vandenabeele, P.4    D'Herde, K.5
  • 28
    • 2442696377 scopus 로고    scopus 로고
    • Excessive apoptosis of guinea pig colonocytes may lead to an imbalance between phagocytosis and degradation in vivo
    • Groos S, Busche R, von Engelhardt W, Reale E, Luciano L. Excessive apoptosis of guinea pig colonocytes may lead to an imbalance between phagocytosis and degradation in vivo. Cell Tissue Res 2004;316:77-86.
    • (2004) Cell Tissue Res , vol.316 , pp. 77-86
    • Groos, S.1    Busche, R.2    Von Engelhardt, W.3    Reale, E.4    Luciano, L.5
  • 29
    • 0033802236 scopus 로고    scopus 로고
    • NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease
    • Kono H, Rusyn I, Yin M, Gabele E, Yamashina S, Dikalova A, et al. NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease. J Clin Invest 2000;106:867-872.
    • (2000) J Clin Invest , vol.106 , pp. 867-872
    • Kono, H.1    Rusyn, I.2    Yin, M.3    Gabele, E.4    Yamashina, S.5    Dikalova, A.6
  • 30
    • 0347986777 scopus 로고    scopus 로고
    • NADPH oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosis
    • Bataller R, Schwabe RF, Choi YH, Yang L, Paik YH, Lindquist J, et al. NADPH oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosis. J Clin Invest 2003;112:1383-1394.
    • (2003) J Clin Invest , vol.112 , pp. 1383-1394
    • Bataller, R.1    Schwabe, R.F.2    Choi, Y.H.3    Yang, L.4    Paik, Y.H.5    Lindquist, J.6
  • 31
    • 0033860297 scopus 로고    scopus 로고
    • Reactive oxygen and mechanisms of inflammatory liver injury
    • Jaeschke H. Reactive oxygen and mechanisms of inflammatory liver injury. J Gastroenterol Hepatol 2000;15:718-724.
    • (2000) J Gastroenterol Hepatol , vol.15 , pp. 718-724
    • Jaeschke, H.1
  • 34
    • 14144255049 scopus 로고    scopus 로고
    • Generation of 8-hydroxydeoxyguanosine from DNA using rat liver homogenates
    • Shi M, Takeshita H, Komatsu M, Xu B, Aoyama K, Takeuchi T. Generation of 8-hydroxydeoxyguanosine from DNA using rat liver homogenates. Cancer Sci 2005;96:13-18.
    • (2005) Cancer Sci , vol.96 , pp. 13-18
    • Shi, M.1    Takeshita, H.2    Komatsu, M.3    Xu, B.4    Aoyama, K.5    Takeuchi, T.6
  • 35
    • 0037022534 scopus 로고    scopus 로고
    • Oxygen metabolism causes chromosome breaks and is associated with the neuronal apoptosis observed in DNA double-strand break repair mutants
    • Karanjawala ZE, Murphy N, Hinton DR, Hsieh CL, Lieber MR. Oxygen metabolism causes chromosome breaks and is associated with the neuronal apoptosis observed in DNA double-strand break repair mutants. Curr Biol 2002;12:397-402.
    • (2002) Curr Biol , vol.12 , pp. 397-402
    • Karanjawala, Z.E.1    Murphy, N.2    Hinton, D.R.3    Hsieh, C.L.4    Lieber, M.R.5
  • 36
    • 0033969322 scopus 로고    scopus 로고
    • Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism
    • Jaiswal M, LaRusso NF, Burgart LJ, Gores GJ. Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism. Cancer Res 2000;60:184-190.
    • (2000) Cancer Res , vol.60 , pp. 184-190
    • Jaiswal, M.1    LaRusso, N.F.2    Burgart, L.J.3    Gores, G.J.4
  • 38
    • 0033053458 scopus 로고    scopus 로고
    • Transforming growth factor beta1 induces the expression of alpha1 (I) procollagen mRNA by a hydrogen peroxide-C/EBPbeta-dependent mechanism in rat hepatic stellate cells
    • Garcia-Trevijano ER, Iraburu MJ, Fontana L, Dominguez-Rosales JA, Auster A, Covarrubias-Pinedo A, et al. Transforming growth factor beta1 induces the expression of alpha1 (I) procollagen mRNA by a hydrogen peroxide-C/EBPbeta- dependent mechanism in rat hepatic stellate cells. HEPATOLOGY 1999;29:960-970.
    • (1999) Hepatology , vol.29 , pp. 960-970
    • Garcia-Trevijano, E.R.1    Iraburu, M.J.2    Fontana, L.3    Dominguez-Rosales, J.A.4    Auster, A.5    Covarrubias-Pinedo, A.6
  • 39
    • 0032835657 scopus 로고    scopus 로고
    • CYP2E1-mediated oxidative stress induces collagen type I expression in rat hepatic stellate cells
    • Nieto N, Friedman SL, Greenwel P, Cederbaum AI. CYP2E1-mediated oxidative stress induces collagen type I expression in rat hepatic stellate cells. HEPATOLOGY 1999;30:987-996.
    • (1999) Hepatology , vol.30 , pp. 987-996
    • Nieto, N.1    Friedman, S.L.2    Greenwel, P.3    Cederbaum, A.I.4
  • 40
    • 0035209395 scopus 로고    scopus 로고
    • The phagocytosis of apoptotic cells
    • Fadok VA, Chimini G. The phagocytosis of apoptotic cells. Semin Immunol 2001;13:365-372.
    • (2001) Semin Immunol , vol.13 , pp. 365-372
    • Fadok, V.A.1    Chimini, G.2
  • 41
    • 0032415964 scopus 로고    scopus 로고
    • Regulation of macrophage cytokine production by phagocytosis of apoptotic and post-apoptotic cells
    • Fadok VA, McDonald PP, Bratton DL, Henson PM. Regulation of macrophage cytokine production by phagocytosis of apoptotic and post-apoptotic cells. Biochem Soc Trans 1998;26:653-656.
    • (1998) Biochem Soc Trans , vol.26 , pp. 653-656
    • Fadok, V.A.1    McDonald, P.P.2    Bratton, D.L.3    Henson, P.M.4
  • 42
    • 0034810089 scopus 로고    scopus 로고
    • Cytokine receptors and signaling in hepatic stellate cells
    • Pinzani M, Marra F. Cytokine receptors and signaling in hepatic stellate cells. Semin Liver Dis 2001;21:397-416.
    • (2001) Semin Liver Dis , vol.21 , pp. 397-416
    • Pinzani, M.1    Marra, F.2
  • 43
    • 7044220856 scopus 로고    scopus 로고
    • Detection of apoptotic caspase activation in sera from patients with chronic HCV infection is associated with fibrotic liver injury
    • Bantel H, Lugering A, Heidemann J, Volkmann X, Poremba C, Strassburg CP, et al. Detection of apoptotic caspase activation in sera from patients with chronic HCV infection is associated with fibrotic liver injury. HEPATOLOGY 2004;40:1078-1087.
    • (2004) Hepatology , vol.40 , pp. 1078-1087
    • Bantel, H.1    Lugering, A.2    Heidemann, J.3    Volkmann, X.4    Poremba, C.5    Strassburg, C.P.6
  • 44
    • 23044449411 scopus 로고    scopus 로고
    • Early response of alpha2(I) collagen to acetaldehyde in human hepatic stellate cells is TGF-beta independent
    • Svegliati-Baroni G, Inagaki Y, Rincon-Sanchez AR, Else C, Saccomanno S, Benedetti A, et al. Early response of alpha2(I) collagen to acetaldehyde in human hepatic stellate cells is TGF-beta independent. HEPATOLOGY 2005;42:343-352.
    • (2005) Hepatology , vol.42 , pp. 343-352
    • Svegliati-Baroni, G.1    Inagaki, Y.2    Rincon-Sanchez, A.R.3    Else, C.4    Saccomanno, S.5    Benedetti, A.6
  • 45
    • 0037177841 scopus 로고    scopus 로고
    • Cross-talk between ERK and p38 MAPK mediates selective suppression of pro-inflammatory cytokines by transforming growth factor-beta
    • Xiao YQ, Malcolm K, Worthen GS, Gardai S, Schiemann WP, Fadok VA, et al. Cross-talk between ERK and p38 MAPK mediates selective suppression of pro-inflammatory cytokines by transforming growth factor-beta. J Biol Chem 2002;277:14884-14893.
    • (2002) J Biol Chem , vol.277 , pp. 14884-14893
    • Xiao, Y.Q.1    Malcolm, K.2    Worthen, G.S.3    Gardai, S.4    Schiemann, W.P.5    Fadok, V.A.6
  • 46
    • 0037174159 scopus 로고    scopus 로고
    • p38 MAPK mediates the regulation of alpha1 (I) procollagen mRNA levels by TNF-alpha and TGF-beta in a cell line of rat hepatic stellate cells(1)
    • Varela-Rey M, Montiel-Duarte C, Oses-Prieto JA, Lopez-Zabalza MJ, Jaffrezou JP, Rojkind M, et al. p38 MAPK mediates the regulation of alpha1 (I) procollagen mRNA levels by TNF-alpha and TGF-beta in a cell line of rat hepatic stellate cells(1). FEBS Lett 2002;528:133-138.
    • (2002) FEBS Lett , vol.528 , pp. 133-138
    • Varela-Rey, M.1    Montiel-Duarte, C.2    Oses-Prieto, J.A.3    Lopez-Zabalza, M.J.4    Jaffrezou, J.P.5    Rojkind, M.6
  • 47
    • 0036840372 scopus 로고    scopus 로고
    • DLPC decreases TGF-beta1-induced collagen mRNA by inhibiting p38 MAPK in hepatic stellate cells
    • Cao Q, Mak KM, Lieber CS. DLPC decreases TGF-beta1-induced collagen mRNA by inhibiting p38 MAPK in hepatic stellate cells. Am J Physiol Gastrointest Liver Physiol 2002;283:G1051-G1061.
    • (2002) Am J Physiol Gastrointest Liver Physiol , vol.283
    • Cao, Q.1    Mak, K.M.2    Lieber, C.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.