Inhibition of inhibitor of κb kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis

Gastroenterology

Volumn 128, Issue 1, 2005, Pages 108-120

  Oakley, Fiona ^a   Meso, Muriel ^a   Iredale, John P ^a   Green, Karen ^a   Marek, Carylyn J ^b   Zhou, Xiaoying ^a   May, Michael J ^c   Millward Sadler, Harry ^a   Wright, Matthew C ^b   Mann, Derek A ^a,d  

^a Devmt Environ (CDE) Univ S   (United Kingdom)

^b UNIVERSITY OF ABERDEEN   (United Kingdom)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d Level D   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ACTIN; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; ANTIFIBROTIC AGENT; CARBON TETRACHLORIDE; GADD45 BETA PROTEIN; GELATINASE A; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 9; PROCOLLAGEN; PROCOLLAGEN 1; SALAZOSULFAPYRIDINE; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; TISSUE INHIBITOR OF METALLOPROTEINASE 1; UNCLASSIFIED DRUG; ANTHRA(1,9 CD)PYRAZOL 6(2H) ONE; ANTHRA(1,9-CD)PYRAZOL-6(2H)-ONE; ANTHRACENE DERIVATIVE; ENZYME INHIBITOR; GASTROINTESTINAL AGENT; NF KAPPA B KINASE; NF-KAPPA B KINASE; PROTEIN SERINE THREONINE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL CULTURE; CELL MEMBRANE PERMEABILITY; CELL STIMULATION; CELL SURVIVAL; CHRONIC DISEASE; CONTROLLED STUDY; DRUG CLEARANCE; DRUG SELECTIVITY; DRUG TARGETING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LIVER CELL; LIVER FIBROSIS; LIVER INJURY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SCORING SYSTEM; SMOOTH MUSCLE; STELLATE CELL; ANIMAL; CULTURE TECHNIQUE; CYTOLOGY; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; LIVER; LIVER CIRRHOSIS; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; ANTHRACENES; APOPTOSIS; CELL CULTURE TECHNIQUES; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; GASTROINTESTINAL AGENTS; HUMANS; LIVER; LIVER CIRRHOSIS; MALE; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SULFASALAZINE;

EID: 11144325650     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2004.10.003     Document Type: Article

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