메뉴 건너뛰기




Volumn 19, Issue 2, 1999, Pages 129-140

Cytokines and fibrogenesis

Author keywords

Fibrogenesis; Receptors; Stellate cells

Indexed keywords

CYTOKINE; GAMMA INTERFERON; RETINOID; RETINOL;

EID: 0032794576     PISSN: 02728087     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-1007105     Document Type: Review
Times cited : (354)

References (156)
  • 1
    • 0028938520 scopus 로고
    • Type VI collagen gene expression in experimental liver fibrosis: Quantitation and spatial distribution of mRNAs, and immunodetection of the protein
    • Takahara T, Sollberg S, Muona P, Uitto J. Type VI collagen gene expression in experimental liver fibrosis: Quantitation and spatial distribution of mRNAs, and immunodetection of the protein. Liver 1995;15:78-86
    • (1995) Liver , vol.15 , pp. 78-86
    • Takahara, T.1    Sollberg, S.2    Muona, P.3    Uitto, J.4
  • 2
    • 0028101317 scopus 로고
    • Undulin RNA and protein expression in normal and fibrotic human liver
    • Milani S, Grappone C, Pellegrini G, et al. Undulin RNA and protein expression in normal and fibrotic human liver. Hepatology 1994;20:908-916
    • (1994) Hepatology , vol.20 , pp. 908-916
    • Milani, S.1    Grappone, C.2    Pellegrini, G.3
  • 3
    • 0345335480 scopus 로고    scopus 로고
    • Collagen XVIII is localized in sinusoids and basement membranes and is expressed by hepatocytes
    • Musso O, Rehn M, Saarela J, et al. Collagen XVIII is localized in sinusoids and basement membranes and is expressed by hepatocytes. Hepatology 1998;27:98-107
    • (1998) Hepatology , vol.27 , pp. 98-107
    • Musso, O.1    Rehn, M.2    Saarela, J.3
  • 4
    • 0028967282 scopus 로고
    • Expression of SPARC in normal and fibrotic livers
    • Frizell E, Liu SL, Abraham A, et al. Expression of SPARC in normal and fibrotic livers. Hepatology 1995;21:847-854
    • (1995) Hepatology , vol.21 , pp. 847-854
    • Frizell, E.1    Liu, S.L.2    Abraham, A.3
  • 5
    • 0024314801 scopus 로고
    • Maintenance of differentiated phenotype of cultured rai hepatic lipocytes by basement membrane matrix
    • Friedman SL, Roll FJ, Boyles J, et al. Maintenance of differentiated phenotype of cultured rai hepatic lipocytes by basement membrane matrix. J Biol Chem 1989;264:10756-10762
    • (1989) J Biol Chem , vol.264 , pp. 10756-10762
    • Friedman, S.L.1    Roll, F.J.2    Boyles, J.3
  • 6
    • 0023090714 scopus 로고
    • Support of cultured hepatocytes by a laminin-rich gel. Evidence for a functionally significant subendothelial matrix in normal rat liver
    • Bissell DM, Arenson DM, Maher JJ, Roll FJ. Support of cultured hepatocytes by a laminin-rich gel. Evidence for a functionally significant subendothelial matrix in normal rat liver. J Clin Invest 1987;79:801-812
    • (1987) J Clin Invest , vol.79 , pp. 801-812
    • Bissell, D.M.1    Arenson, D.M.2    Maher, J.J.3    Roll, F.J.4
  • 7
    • 0030271572 scopus 로고    scopus 로고
    • Macromolecular organization of basement membranes
    • Timpl R. Macromolecular organization of basement membranes. Curr Opin Cell Biol 1996;8:618-624
    • (1996) Curr Opin Cell Biol , vol.8 , pp. 618-624
    • Timpl, R.1
  • 8
    • 0028987936 scopus 로고
    • Integrins and signal transduction pathways: The road taken
    • Clark EA, Brugge JS. Integrins and signal transduction pathways: The road taken. Science 1995;268:233-239
    • (1995) Science , vol.268 , pp. 233-239
    • Clark, E.A.1    Brugge, J.S.2
  • 9
    • 0029035265 scopus 로고
    • Expression of cell-matrix adhesion molecules in the liver and their modulation during fibrosis
    • Scoazec JY. Expression of cell-matrix adhesion molecules in the liver and their modulation during fibrosis. J Hepatol 1995;22:20-27
    • (1995) J Hepatol , vol.22 , pp. 20-27
    • Scoazec, J.Y.1
  • 10
    • 0028596335 scopus 로고
    • Expression of variant fibronectins in wound healing: Cellular source and biological activity of the EIIIA segment in rat hepatic fibrogenesis
    • Jarnagin WR, Rockey DC, Koteliansky VE, et al. Expression of variant fibronectins in wound healing: Cellular source and biological activity of the EIIIA segment in rat hepatic fibrogenesis. J Cell Biol 1994;127:2037-2048
    • (1994) J Cell Biol , vol.127 , pp. 2037-2048
    • Jarnagin, W.R.1    Rockey, D.C.2    Koteliansky, V.E.3
  • 11
    • 0029913735 scopus 로고    scopus 로고
    • Expression and function of integrin receptors for collagen and laminin in cultured human hepatic stellate cells
    • Carloni V, Romanelli RG, Pinzani M, et al. Expression and function of integrin receptors for collagen and laminin in cultured human hepatic stellate cells. Gastroenterology 1996;110:1127-1136
    • (1996) Gastroenterology , vol.110 , pp. 1127-1136
    • Carloni, V.1    Romanelli, R.G.2    Pinzani, M.3
  • 12
    • 0031042108 scopus 로고    scopus 로고
    • Focal adhesion kinase and phospholipase C gamma involvement in adhesion and migration of human hepatic stellate cells
    • Carloni V, Romanelli RG, Pinzani M, et al. Focal adhesion kinase and phospholipase C gamma involvement in adhesion and migration of human hepatic stellate cells. Gastroenterology 1997;112:522-531
    • (1997) Gastroenterology , vol.112 , pp. 522-531
    • Carloni, V.1    Romanelli, R.G.2    Pinzani, M.3
  • 13
    • 0030609161 scopus 로고    scopus 로고
    • The role of alpha 1 beta 1 integrin in wound contraction. A quantitative analysis of liver myofibroblasts in vivo and in primary culture
    • Racine-Samson L, Rockey DC, Bissell DM. The role of alpha 1 beta 1 integrin in wound contraction. A quantitative analysis of liver myofibroblasts in vivo and in primary culture. J Biol Chem 1997;272:30911-30917
    • (1997) J Biol Chem , vol.272 , pp. 30911-30917
    • Racine-Samson, L.1    Rockey, D.C.2    Bissell, D.M.3
  • 14
    • 0031917311 scopus 로고    scopus 로고
    • Morphology of sites of adhesion between hepatic stellate cells (vitamin A-storing cells) and a three-dimensional extracellular matrix
    • Imai K, Senoo H. Morphology of sites of adhesion between hepatic stellate cells (vitamin A-storing cells) and a three-dimensional extracellular matrix. Anat Rec 1998;250:430-437
    • (1998) Anat Rec , vol.250 , pp. 430-437
    • Imai, K.1    Senoo, H.2
  • 15
    • 0031310941 scopus 로고    scopus 로고
    • An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors
    • Shrivastava A, Radziejewski C, Campbell E, et al. An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors. Mol Cell 1997;1:25-34
    • (1997) Mol Cell , vol.1 , pp. 25-34
    • Shrivastava, A.1    Radziejewski, C.2    Campbell, E.3
  • 16
    • 0031309902 scopus 로고    scopus 로고
    • The discoidin domain receptor tyrosine kinases are activated by collagen
    • Vogel W, Gish GD, Alves F, Pawson T. The discoidin domain receptor tyrosine kinases are activated by collagen. Mol Cell 1997;1:13-23
    • (1997) Mol Cell , vol.1 , pp. 13-23
    • Vogel, W.1    Gish, G.D.2    Alves, F.3    Pawson, T.4
  • 17
    • 0032500172 scopus 로고    scopus 로고
    • Coordinated induction of VEGF receptors in mesenchymal cell types during rat hepatic wound healing
    • Ankoma-Sey V, Matli M, Chang KB, et al. Coordinated induction of VEGF receptors in mesenchymal cell types during rat hepatic wound healing. Oncogene 1998;17:115-121
    • (1998) Oncogene , vol.17 , pp. 115-121
    • Ankoma-Sey, V.1    Matli, M.2    Chang, K.B.3
  • 18
    • 0025000652 scopus 로고
    • Extracellular matrix gene expression increases preferentially in rat lipocytes and sinusoidal endothelial cells during hepatic fibrosis in vivo
    • Maher JJ, McGuire RF. Extracellular matrix gene expression increases preferentially in rat lipocytes and sinusoidal endothelial cells during hepatic fibrosis in vivo. J Clin Invest 1990;86: 1641-1648
    • (1990) J Clin Invest , vol.86 , pp. 1641-1648
    • Maher, J.J.1    McGuire, R.F.2
  • 19
    • 0028948718 scopus 로고
    • Heparan sulfate proteoglycan expression in normal human liver
    • Roskams T, Moshage H, De Vos R, et al. Heparan sulfate proteoglycan expression in normal human liver. Hepatology 1995;21: 950-958
    • (1995) Hepatology , vol.21 , pp. 950-958
    • Roskams, T.1    Moshage, H.2    De Vos, R.3
  • 20
    • 0027441601 scopus 로고
    • Distribution and origin of the basement membrane component perlecan in rat liver and primary hepatocyte culture
    • Rescan PY, Loreal O, Hassell JR, et al. Distribution and origin of the basement membrane component perlecan in rat liver and primary hepatocyte culture. Am J Pathol 1993;142:199-208
    • (1993) Am J Pathol , vol.142 , pp. 199-208
    • Rescan, P.Y.1    Loreal, O.2    Hassell, J.R.3
  • 21
    • 0029865809 scopus 로고    scopus 로고
    • Expression of extracellular matrix proteoglycans perlecan and decorin in carbon-tetrachloride-injured rat liver and in isolated liver cells
    • Gallai M, Kovalszky I, Knittel T, et al. Expression of extracellular matrix proteoglycans perlecan and decorin in carbon-tetrachloride-injured rat liver and in isolated liver cells. Am J Pathol 1996;148:1463-1471
    • (1996) Am J Pathol , vol.148 , pp. 1463-1471
    • Gallai, M.1    Kovalszky, I.2    Knittel, T.3
  • 22
    • 0029144666 scopus 로고
    • Roles of oxidative stress in activation of Kupffer and Ito cells in liver fibrogenesis
    • Tsukamoto H, Rippe R, Niemela O, Lin M. Roles of oxidative stress in activation of Kupffer and Ito cells in liver fibrogenesis. J Gastroenterol Hepatol 1995;10(suppl 1):S50-53
    • (1995) J Gastroenterol Hepatol , vol.10 , Issue.SUPPL. 1
    • Tsukamoto, H.1    Rippe, R.2    Niemela, O.3    Lin, M.4
  • 23
    • 0029026661 scopus 로고
    • Cytokines and cellular crosstalk involved in the activation of fat-storing cells
    • Gressner AM. Cytokines and cellular crosstalk involved in the activation of fat-storing cells. J Hepatol 1995;22:28-36
    • (1995) J Hepatol , vol.22 , pp. 28-36
    • Gressner, A.M.1
  • 24
    • 0028123105 scopus 로고
    • Quantitative analysis of macrophages and perisinusoidal cells in primary biliary cirrhosis
    • Mathew J, Hines JE, Toole K, et al. Quantitative analysis of macrophages and perisinusoidal cells in primary biliary cirrhosis. Histopathology 1994;25:65-70
    • (1994) Histopathology , vol.25 , pp. 65-70
    • Mathew, J.1    Hines, J.E.2    Toole, K.3
  • 25
    • 0026579161 scopus 로고
    • Macrophage and perisinusoidal cell kinetics in acute liver injury
    • Johnson SJ, Hines JE, Burt AD. Macrophage and perisinusoidal cell kinetics in acute liver injury. J Pathol 1992;166:351-358
    • (1992) J Pathol , vol.166 , pp. 351-358
    • Johnson, S.J.1    Hines, J.E.2    Burt, A.D.3
  • 26
    • 0029057032 scopus 로고
    • Experimental biliary fibrosis correlates with increased numbers of fat-storing and Kupffer cells, and portal endotoxemia
    • Grinko I, Geerts A, Wisse E. Experimental biliary fibrosis correlates with increased numbers of fat-storing and Kupffer cells, and portal endotoxemia. J Hepatol 1995;23:449-458
    • (1995) J Hepatol , vol.23 , pp. 449-458
    • Grinko, I.1    Geerts, A.2    Wisse, E.3
  • 27
    • 0023785310 scopus 로고
    • Proliferation of fat-storing cells is stimulated by secretions of Kupffer cells from normal and injured liver
    • Zerbe O, Gressner AM. Proliferation of fat-storing cells is stimulated by secretions of Kupffer cells from normal and injured liver. Exp Mol Pathol 1988;49:87-101
    • (1988) Exp Mol Pathol , vol.49 , pp. 87-101
    • Zerbe, O.1    Gressner, A.M.2
  • 28
    • 0024852111 scopus 로고
    • Activation of cultured rat hepatic lipocytes by Kupffer cell conditioned medium. Direct enhancement of matrix synthesis and stimulation of cell proliferation via induction of platelet-derived growth factor receptors
    • Friedman SL, Arthur MJ. Activation of cultured rat hepatic lipocytes by Kupffer cell conditioned medium. Direct enhancement of matrix synthesis and stimulation of cell proliferation via induction of platelet-derived growth factor receptors. J Clin Invest 1989;84:1780-1785
    • (1989) J Clin Invest , vol.84 , pp. 1780-1785
    • Friedman, S.L.1    Arthur, M.J.2
  • 29
    • 0029360385 scopus 로고
    • Rat hepatic lipocytes synthesize and secrete transin (stromelysin) in early primary culture
    • Vyas SK, Leyland H, Gentry J, Arthur MJ. Rat hepatic lipocytes synthesize and secrete transin (stromelysin) in early primary culture. Gastroenterology 1995;109:889-898
    • (1995) Gastroenterology , vol.109 , pp. 889-898
    • Vyas, S.K.1    Leyland, H.2    Gentry, J.3    Arthur, M.J.4
  • 30
    • 0029998086 scopus 로고    scopus 로고
    • The plasminogen-activating system in hepatic stellate cells
    • Leyland H, Gentry J, Arthur MJ, Benyon RC. The plasminogen-activating system in hepatic stellate cells. Hepatology 1996;24: 1172-1178
    • (1996) Hepatology , vol.24 , pp. 1172-1178
    • Leyland, H.1    Gentry, J.2    Arthur, M.J.3    Benyon, R.C.4
  • 31
    • 0030724689 scopus 로고    scopus 로고
    • Dual expression of matrix metalloproteinase-2 and membrane-type 1-matrix metalloproteinase in fibrotic human livers
    • Takahara T, Furui K, Yata Y, et al. Dual expression of matrix metalloproteinase-2 and membrane-type 1-matrix metalloproteinase in fibrotic human livers. Hepatology 1997;26:1521-1529
    • (1997) Hepatology , vol.26 , pp. 1521-1529
    • Takahara, T.1    Furui, K.2    Yata, Y.3
  • 32
    • 0029024766 scopus 로고
    • Collagenases and liver fibrosis
    • Arthur MJ. Collagenases and liver fibrosis. J Hepatol 1995;22:43-48
    • (1995) J Hepatol , vol.22 , pp. 43-48
    • Arthur, M.J.1
  • 33
    • 0028291795 scopus 로고
    • Differential expression of matrix-metalloproteinase-1 and -2 genes in normal and fibrotic human liver
    • Milani S, Herbst H, Schuppan D, et al. Differential expression of matrix-metalloproteinase-1 and -2 genes in normal and fibrotic human liver. Am J Pathol 1994;144:528-537
    • (1994) Am J Pathol , vol.144 , pp. 528-537
    • Milani, S.1    Herbst, H.2    Schuppan, D.3
  • 34
    • 0030934411 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinase-1 and -2 RNA expression in rat and human liver fibrosis
    • Herbst H, Wege T, Milani S, et al. Tissue inhibitor of metalloproteinase-1 and -2 RNA expression in rat and human liver fibrosis. Am J Pathol 1997;150:1647-1659
    • (1997) Am J Pathol , vol.150 , pp. 1647-1659
    • Herbst, H.1    Wege, T.2    Milani, S.3
  • 35
    • 0030030039 scopus 로고    scopus 로고
    • Expression of tissue inhibitor of metalloproteinases 1 and 2 is increased in fibrotic human liver
    • Benyon RC, Iredale JP, Goddard S, et al. Expression of tissue inhibitor of metalloproteinases 1 and 2 is increased in fibrotic human liver. Gastroenterology 1996;110:821-831
    • (1996) Gastroenterology , vol.110 , pp. 821-831
    • Benyon, R.C.1    Iredale, J.P.2    Goddard, S.3
  • 36
    • 0029055170 scopus 로고
    • Tissue inhibitor of metalloproteinase-I and interstitial collagenase expression in autoimmune chronic active hepatitis and activated human hepatic lipocytes
    • Iredale JP, Goddard S, Murphy G, et al. Tissue inhibitor of metalloproteinase-I and interstitial collagenase expression in autoimmune chronic active hepatitis and activated human hepatic lipocytes. Clin Sci 1995;89:75-81
    • (1995) Clin Sci , vol.89 , pp. 75-81
    • Iredale, J.P.1    Goddard, S.2    Murphy, G.3
  • 37
    • 0029888478 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinase-1 messenger RNA expression is enhanced rela-tive to interstitial collagenase messenger RNA in experimental liver injury and fibrosis
    • Iredale JP, Benyon RC, Arthur MJ, et al. Tissue inhibitor of metalloproteinase-1 messenger RNA expression is enhanced rela-tive to interstitial collagenase messenger RNA in experimental liver injury and fibrosis. Hepatology 1996;24:176-184
    • (1996) Hepatology , vol.24 , pp. 176-184
    • Iredale, J.P.1    Benyon, R.C.2    Arthur, M.J.3
  • 38
    • 0031018997 scopus 로고    scopus 로고
    • Tissue inhibitors of metalloproteinases in liver fibrosis
    • Iredale JP. Tissue inhibitors of metalloproteinases in liver fibrosis. Int J Biochem Cell Biol 1997;29:43-54
    • (1997) Int J Biochem Cell Biol , vol.29 , pp. 43-54
    • Iredale, J.P.1
  • 39
    • 0026453596 scopus 로고
    • Secretion of 72 kDa type IV collagenase/gelatinase by cultured human lipocytes. Analysis of gene expression, protein synthesis and proteinase activity
    • Arthur MJ, Stanley A, Iredale JP, et al. Secretion of 72 kDa type IV collagenase/gelatinase by cultured human lipocytes. Analysis of gene expression, protein synthesis and proteinase activity. Biochem J 1992;287:701-707
    • (1992) Biochem J , vol.287 , pp. 701-707
    • Arthur, M.J.1    Stanley, A.2    Iredale, J.P.3
  • 40
    • 0028291795 scopus 로고
    • Differential expression of matrix-metalloproteinase-1 and -2 genes in normal and fibrotic human liver
    • Milani S, Herbst H, Schuppan D, et al. Differential expression of matrix-metalloproteinase-1 and -2 genes in normal and fibrotic human liver. Am J Pathol 1994;144:528-537
    • (1994) Am J Pathol , vol.144 , pp. 528-537
    • Milani, S.1    Herbst, H.2    Schuppan, D.3
  • 41
    • 0030786204 scopus 로고    scopus 로고
    • Fibronectin and cytokines increase JNK, ERK, AP-1 activity, and transin gene expression in rat hepatic stellate cells
    • Poulos JE, Baldassare JJ, Bacon BR, et al. Fibronectin and cytokines increase JNK, ERK, AP-1 activity, and transin gene expression in rat hepatic stellate cells. Am J Physiol 1997;273: G804-811
    • (1997) Am J Physiol , vol.273
    • Poulos, J.E.1    Baldassare, J.J.2    Bacon, B.R.3
  • 42
    • 0031013140 scopus 로고    scopus 로고
    • Activation of matrix metalloproteinase-2 from hepatic stellate cells requires interactions with hepatocytes
    • Theret N, Musso O, L'Helgoualc'h A, Clement B. Activation of matrix metalloproteinase-2 from hepatic stellate cells requires interactions with hepatocytes. Am J Pathol 1997;150:51-58
    • (1997) Am J Pathol , vol.150 , pp. 51-58
    • Theret, N.1    Musso, O.2    L'Helgoualc'h, A.3    Clement, B.4
  • 43
    • 0029133207 scopus 로고
    • Kupffer cell-derived 95-kd type IV collagenase/gelatinase B: Characterization and expression in cultured cells
    • Winwood PJ, Schuppan D, Iredale JP, et al. Kupffer cell-derived 95-kd type IV collagenase/gelatinase B: Characterization and expression in cultured cells. Hepatology 1995;22:304-315
    • (1995) Hepatology , vol.22 , pp. 304-315
    • Winwood, P.J.1    Schuppan, D.2    Iredale, J.P.3
  • 44
    • 0031972755 scopus 로고    scopus 로고
    • Expression of interleukin-10 by in vitro and in vivo activated hepatic stellate cells
    • Wang SC, Tsukamoto H, Rippe RA, et al. Expression of interleukin-10 by in vitro and in vivo activated hepatic stellate cells. J Biol Chem 1998;273:302-308
    • (1998) J Biol Chem , vol.273 , pp. 302-308
    • Wang, S.C.1    Tsukamoto, H.2    Rippe, R.A.3
  • 45
    • 0028679641 scopus 로고
    • Interferon gamma inhibits lipocyte activation and extracellular matrix mRNA expression during experimental liver injury: Implications for treatment of hepatic fibrosis
    • Rockey DC, Chung JJ. Interferon gamma inhibits lipocyte activation and extracellular matrix mRNA expression during experimental liver injury: Implications for treatment of hepatic fibrosis. J Invest Med 1994;42:660-670
    • (1994) J Invest Med , vol.42 , pp. 660-670
    • Rockey, D.C.1    Chung, J.J.2
  • 46
    • 0030033193 scopus 로고    scopus 로고
    • Transducers of life and death: TNF receptor superfamily and associated proteins
    • Baker SJ, Reddy EP. Transducers of life and death: TNF receptor superfamily and associated proteins. Oncogene 1996;12:1-9
    • (1996) Oncogene , vol.12 , pp. 1-9
    • Baker, S.J.1    Reddy, E.P.2
  • 47
    • 0030453783 scopus 로고    scopus 로고
    • Relaxin induces an extracellular matrix-degrading phenotype in human lung fibroblasts in vitro and inhibits lung fibrosis in a murine model in vivo
    • Unemori EN, Pickford LB, Salles AL, et al. Relaxin induces an extracellular matrix-degrading phenotype in human lung fibroblasts in vitro and inhibits lung fibrosis in a murine model in vivo. J Clin Invest 1996;98:2739-2745
    • (1996) J Clin Invest , vol.98 , pp. 2739-2745
    • Unemori, E.N.1    Pickford, L.B.2    Salles, A.L.3
  • 48
    • 0028138246 scopus 로고
    • Relaxin: Structures, functions, promises, and nonevolution
    • Schwabe C, Bullesbach EE. Relaxin: Structures, functions, promises, and nonevolution. FASEB J 1994;8:1152-1160
    • (1994) FASEB J , vol.8 , pp. 1152-1160
    • Schwabe, C.1    Bullesbach, E.E.2
  • 49
    • 0031973105 scopus 로고    scopus 로고
    • Collagens in the liver extracellular matrix bind hepatocyte growth factor
    • Schuppan D, Schmid M, Somasundaram R, et al. Collagens in the liver extracellular matrix bind hepatocyte growth factor. Gastroenterology 1998;114:139-152
    • (1998) Gastroenterology , vol.114 , pp. 139-152
    • Schuppan, D.1    Schmid, M.2    Somasundaram, R.3
  • 50
    • 0029909655 scopus 로고    scopus 로고
    • Type I, II, III, IV, V, and VI collagens serve as extracellular ligands for the isoforms of platelet-derived growth factor (AA, BB, and AB)
    • Somasundaram R, Schuppan D. Type I, II, III, IV, V, and VI collagens serve as extracellular ligands for the isoforms of platelet-derived growth factor (AA, BB, and AB). J Biol Chem 1996;271:26884-26891
    • (1996) J Biol Chem , vol.271 , pp. 26884-26891
    • Somasundaram, R.1    Schuppan, D.2
  • 51
    • 0031046646 scopus 로고    scopus 로고
    • Growth factors in the extracellular matrix
    • Taipale J, Keski-Oja J. Growth factors in the extracellular matrix. FASEB J 1997;11:51-59
    • (1997) FASEB J , vol.11 , pp. 51-59
    • Taipale, J.1    Keski-Oja, J.2
  • 52
    • 0031930768 scopus 로고    scopus 로고
    • Signal transduction in hepatic stellate cells
    • Pinzani M, Marra F, Carloni V. Signal transduction in hepatic stellate cells. Liver 1998;18:2-13
    • (1998) Liver , vol.18 , pp. 2-13
    • Pinzani, M.1    Marra, F.2    Carloni, V.3
  • 53
    • 0028085979 scopus 로고
    • Regulation of platelet-derived growth factor secretion and gene expression in human liver fat-storing cells
    • Marra F, Choudhury GG, Pinzani M, Abboud HE. Regulation of platelet-derived growth factor secretion and gene expression in human liver fat-storing cells. Gastroenterology 1994;107: 1110-1117
    • (1994) Gastroenterology , vol.107 , pp. 1110-1117
    • Marra, F.1    Choudhury, G.G.2    Pinzani, M.3    Abboud, H.E.4
  • 54
    • 0028137446 scopus 로고
    • Signal transduction by the PDGF receptors
    • Claesson-Welsh L. Signal transduction by the PDGF receptors. Prog Growth Factor Res 1994;5:37-54
    • (1994) Prog Growth Factor Res , vol.5 , pp. 37-54
    • Claesson-Welsh, L.1
  • 55
    • 0031793551 scopus 로고    scopus 로고
    • Subcellular localization of (latent) TGFbeta and latent TGFbeta binding protein (LTBP-1) in rat hepatocytes and hepatic stellate cells
    • Roth S, Kuhl K, Gressner AM. Subcellular localization of (latent) TGFbeta and latent TGFbeta binding protein (LTBP-1) in rat hepatocytes and hepatic stellate cells. Hepatology 1998;28:1588-1596
    • (1998) Hepatology , vol.28 , pp. 1588-1596
    • Roth, S.1    Kuhl, K.2    Gressner, A.M.3
  • 56
    • 0031892802 scopus 로고    scopus 로고
    • Isoforms and splice variant of transforming growth factor beta-binding protein in rat hepatic stellate cells
    • Gong W, Gressner AM, Michel K, Roth S. Isoforms and splice variant of transforming growth factor beta-binding protein in rat hepatic stellate cells. Gastroenterology 1998;114:352-363
    • (1998) Gastroenterology , vol.114 , pp. 352-363
    • Gong, W.1    Gressner, A.M.2    Michel, K.3    Roth, S.4
  • 57
    • 0030755313 scopus 로고    scopus 로고
    • Retinoids exacerbate rat liver fibrosis by inducing the activation of latent TGF-beta in liver stellate cells
    • Okuno M, Moriwaki H, Imai S, et al. Retinoids exacerbate rat liver fibrosis by inducing the activation of latent TGF-beta in liver stellate cells [see comments]. Hepatology 1997;26:913-921
    • (1997) Hepatology , vol.26 , pp. 913-921
    • Okuno, M.1    Moriwaki, H.2    Imai, S.3
  • 58
    • 12344320716 scopus 로고    scopus 로고
    • Thrombospondin-1 is a major activator of TGF-beta1 in vivo
    • Crawford SE, Stellmach V, Murphy-Ullrich JE, et al. Thrombospondin-1 is a major activator of TGF-beta1 in vivo. Cell 1998;93:1159-1170
    • (1998) Cell , vol.93 , pp. 1159-1170
    • Crawford, S.E.1    Stellmach, V.2    Murphy-Ullrich, J.E.3
  • 59
    • 0029841151 scopus 로고    scopus 로고
    • Gene expression and regulation of plasminogen activator inhibitor type I in hepatic stellate cells of rat liver
    • Knittel T, Fellmer P, Ramadori G. Gene expression and regulation of plasminogen activator inhibitor type I in hepatic stellate cells of rat liver. Gastroenterology 1996;111:745-754
    • (1996) Gastroenterology , vol.111 , pp. 745-754
    • Knittel, T.1    Fellmer, P.2    Ramadori, G.3
  • 60
    • 0029117185 scopus 로고
    • Focal nodular hyperplasia of the liver: Composition of the extracellular matrix and expression of cell-cell and cell-matrix adhesion molecules
    • Scoazec JY, Flejou JF, D'Errico A, et al. Focal nodular hyperplasia of the liver: Composition of the extracellular matrix and expression of cell-cell and cell-matrix adhesion molecules. Hum Pathol 1995;26:1114-1125
    • (1995) Hum Pathol , vol.26 , pp. 1114-1125
    • Scoazec, J.Y.1    Flejou, J.F.2    D'Errico, A.3
  • 61
    • 0028170153 scopus 로고
    • Induction of beta-platelet-derived growth factor receptor in rat hepatic lipocytes during cellular activation in vivo and in culture
    • Wong L, Yamasaki G, Johnson RJ, Friedman SL. Induction of beta-platelet-derived growth factor receptor in rat hepatic lipocytes during cellular activation in vivo and in culture. J Clin Invest 1994;94:1563-1569
    • (1994) J Clin Invest , vol.94 , pp. 1563-1569
    • Wong, L.1    Yamasaki, G.2    Johnson, R.J.3    Friedman, S.L.4
  • 62
    • 0028289518 scopus 로고
    • Modulation of transforming growth factor beta receptors of rat lipocytes during the hepatic wound healing response. Enhanced binding and reduced gene expression accompany cellular activation in culture and in vivo
    • Friedman SL, Yamasaki G, Wong L. Modulation of transforming growth factor beta receptors of rat lipocytes during the hepatic wound healing response. Enhanced binding and reduced gene expression accompany cellular activation in culture and in vivo. J Biol Chem 1994;269:10551-10558
    • (1994) J Biol Chem , vol.269 , pp. 10551-10558
    • Friedman, S.L.1    Yamasaki, G.2    Wong, L.3
  • 63
    • 0031891508 scopus 로고    scopus 로고
    • Expression of the thrombin receptor in human liver: Up-regulation during acute and chronic injury
    • Marra F, DeFranco R, Grappone C, et al. Expression of the thrombin receptor in human liver: Up-regulation during acute and chronic injury. Hepatology 1998;27:462-471
    • (1998) Hepatology , vol.27 , pp. 462-471
    • Marra, F.1    DeFranco, R.2    Grappone, C.3
  • 64
    • 0026583942 scopus 로고
    • PDGF alpha-and beta-receptors activate unique and common signal transduction pathways
    • Eriksson A, Siegbahn A, Westermark B, et al. PDGF alpha-and beta-receptors activate unique and common signal transduction pathways. EMBO J 1992;11:543-550
    • (1992) EMBO J , vol.11 , pp. 543-550
    • Eriksson, A.1    Siegbahn, A.2    Westermark, B.3
  • 65
    • 0030970555 scopus 로고    scopus 로고
    • Closing in on the signals of hepatic fibrosis
    • Friedman SL. Closing in on the signals of hepatic fibrosis [editorial: comment]. Gastroenterology 1997;112:1406-1409
    • (1997) Gastroenterology , vol.112 , pp. 1406-1409
    • Friedman, S.L.1
  • 66
    • 2142843806 scopus 로고    scopus 로고
    • Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions
    • Pinkas-Kramarski R, Soussan L, Waterman H, et al. Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions. EMBO J 1996; 15:2452-2467
    • (1996) EMBO J , vol.15 , pp. 2452-2467
    • Pinkas-Kramarski, R.1    Soussan, L.2    Waterman, H.3
  • 67
    • 0028170226 scopus 로고
    • Mechanism of activation of the TGF-beta receptor
    • Wrana JL, Attisano L, Wieser R, et al. Mechanism of activation of the TGF-beta receptor. Nature 1994;370:341-347
    • (1994) Nature , vol.370 , pp. 341-347
    • Wrana, J.L.1    Attisano, L.2    Wieser, R.3
  • 68
    • 0028838012 scopus 로고
    • Dimerization of cell surface receptors in signal transduction
    • Heldin CH. Dimerization of cell surface receptors in signal transduction. Cell 1995;80:213-223
    • (1995) Cell , vol.80 , pp. 213-223
    • Heldin, C.H.1
  • 69
    • 0028176477 scopus 로고
    • A neu acquaintance for erbB3 and erbB4: A role for receptor heterodimerization in growth signaling
    • Carraway KLR, Cantley LC. A neu acquaintance for erbB3 and erbB4: A role for receptor heterodimerization in growth signaling. Cell 1994;78:5-8
    • (1994) Cell , vol.78 , pp. 5-8
    • Carraway, K.L.R.1    Cantley, L.C.2
  • 70
    • 0029133702 scopus 로고
    • Requirement for MAP kinase (ERK2) activity in interferon alpha-and interferon beta-stimulated gene expression through STAT proteins
    • David M, Petricoin ER, Benjamin C, et al. Requirement for MAP kinase (ERK2) activity in interferon alpha-and interferon beta-stimulated gene expression through STAT proteins [see comments]. Science 1995;269:1721-1723
    • (1995) Science , vol.269 , pp. 1721-1723
    • David, M.1    Petricoin, E.R.2    Benjamin, C.3
  • 71
    • 2642605344 scopus 로고    scopus 로고
    • Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases
    • de Caestecker MP, Parks WT, Frank CJ, et al. Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases. Genes Dev 1998;12:1587-1592
    • (1998) Genes Dev , vol.12 , pp. 1587-1592
    • De Caestecker, M.P.1    Parks, W.T.2    Frank, C.J.3
  • 72
    • 0031737792 scopus 로고    scopus 로고
    • Activation of rat hepatic stellate cells in culture is associated with increased sensitivity to endothelin-1
    • Reinehr RM, Kubitz R, Peters-Regehr T, et al. Activation of rat hepatic stellate cells in culture is associated with increased sensitivity to endothelin-1. Hepatology 1998;28:1566-1577
    • (1998) Hepatology , vol.28 , pp. 1566-1577
    • Reinehr, R.M.1    Kubitz, R.2    Peters-Regehr, T.3
  • 73
    • 0027496798 scopus 로고
    • Endothelin receptors in rat liver: Lipocytes as a contractile target for endothelin 1
    • Housset C, Rockey DC, Bissell DM. Endothelin receptors in rat liver: Lipocytes as a contractile target for endothelin 1. Proc Natl Acad Sci USA 1993;90:9266-9270
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 9266-9270
    • Housset, C.1    Rockey, D.C.2    Bissell, D.M.3
  • 74
    • 0025732353 scopus 로고
    • Expression of smooth muscle cell phenotype by rat mesangial cells in immune complex nephritis. Alpha-smooth muscle actin is a marker of mesangial cell proliferation
    • Johnson RJ, Iida H, Alpers CE, et al. Expression of smooth muscle cell phenotype by rat mesangial cells in immune complex nephritis. Alpha-smooth muscle actin is a marker of mesangial cell proliferation. J Clin Invest 1991;87:847-858
    • (1991) J Clin Invest , vol.87 , pp. 847-858
    • Johnson, R.J.1    Iida, H.2    Alpers, C.E.3
  • 75
    • 0030726792 scopus 로고    scopus 로고
    • Phenotypic modulation of alveolar myofibroblasts in transplanted human lungs
    • Kapanci Y, Kurt AM, Redard M, Gabbiani G. Phenotypic modulation of alveolar myofibroblasts in transplanted human lungs. Mod Pathol 1997;10:1134-1142
    • (1997) Mod Pathol , vol.10 , pp. 1134-1142
    • Kapanci, Y.1    Kurt, A.M.2    Redard, M.3    Gabbiani, G.4
  • 77
    • 0027958521 scopus 로고
    • Ito cell heterogeneity: Desmin-negative Ito cells in normal rat liver
    • Ballardini G, Groff P, Badiali dGL, et al. Ito cell heterogeneity: Desmin-negative Ito cells in normal rat liver. Hepatology 1994; 19:440-446
    • (1994) Hepatology , vol.19 , pp. 440-446
    • Ballardini, G.1    Groff, P.2    Badiali, D.3
  • 78
    • 0028857744 scopus 로고
    • Vitamin A-poor lipocytes: A novel desmin-negative lipocyte subpopulation, which can be activated to myofibroblasts
    • Ramm GA, Britton RS, O'Neill R, et al. Vitamin A-poor lipocytes: A novel desmin-negative lipocyte subpopulation, which can be activated to myofibroblasts. Am J Physiol 1995; 269:G532-541
    • (1995) Am J Physiol , vol.269
    • Ramm, G.A.1    Britton, R.S.2    O'Neill, R.3
  • 79
    • 0026766095 scopus 로고
    • Cytoskeleton of liver perisinusoidal cells (lipocytes) in normal and pathological conditions
    • Rockey DC, Friedman SL. Cytoskeleton of liver perisinusoidal cells (lipocytes) in normal and pathological conditions. Cell Motil Cytoskeleton 1992;22:227-234
    • (1992) Cell Motil Cytoskeleton , vol.22 , pp. 227-234
    • Rockey, D.C.1    Friedman, S.L.2
  • 80
    • 0032986367 scopus 로고    scopus 로고
    • Class VI intermediate filament protein nestin is induced during activation of rat hepatic stellate cells
    • Niki T, Pekny M, Hellemans K, et al. Class VI intermediate filament protein nestin is induced during activation of rat hepatic stellate cells. Hepatology 1999;29:520-527
    • (1999) Hepatology , vol.29 , pp. 520-527
    • Niki, T.1    Pekny, M.2    Hellemans, K.3
  • 81
    • 0029801255 scopus 로고    scopus 로고
    • Hepatic stellate cells
    • Friedman SL. Hepatic stellate cells. Prog Liver Dis 1996;14: 101-130
    • (1996) Prog Liver Dis , vol.14 , pp. 101-130
    • Friedman, S.L.1
  • 82
    • 0029997830 scopus 로고    scopus 로고
    • Transdifferentiation of hepatic stellate cells (Ito cells) to myofibroblasts: A key event in hepatic fibrogenesis
    • Gressner AM. Transdifferentiation of hepatic stellate cells (Ito cells) to myofibroblasts: A key event in hepatic fibrogenesis. Kidney Int 1996;54(suppl):S39-45
    • (1996) Kidney Int , vol.54 , Issue.SUPPL.
    • Gressner, A.M.1
  • 83
    • 33746521801 scopus 로고
    • Seminars in medicine of the Beth Israel Hospital, Boston. The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies
    • Friedman SL. Seminars in medicine of the Beth Israel Hospital, Boston. The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies. N Engl J Med 1993;328:1828-1835
    • (1993) N Engl J Med , vol.328 , pp. 1828-1835
    • Friedman, S.L.1
  • 84
    • 0030755313 scopus 로고    scopus 로고
    • Retinoids exacerbate rat liver fibrosis by inducing the activation of latent TGFbeta in liver stellate cells
    • Okuno M, Moriwaki H, Imai S, et al. Retinoids exacerbate rat liver fibrosis by inducing the activation of latent TGFbeta in liver stellate cells. Hepatology 1997;913-921
    • (1997) Hepatology , pp. 913-921
    • Okuno, M.1    Moriwaki, H.2    Imai, S.3
  • 85
    • 0028838193 scopus 로고
    • Activation of hepatic stellate cells by TGF alpha and collagen type I is mediated by oxidative stress through c-myb expression
    • Lee KS, Buck M, Houglum K, Chojkier M. Activation of hepatic stellate cells by TGF alpha and collagen type I is mediated by oxidative stress through c-myb expression. J Clin Invest 1995; 96:2461-2468
    • (1995) J Clin Invest , vol.96 , pp. 2461-2468
    • Lee, K.S.1    Buck, M.2    Houglum, K.3    Chojkier, M.4
  • 86
    • 0030746294 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha inhibits collagen alpha 1(I) gene expression in rat hepatic stellate cells through a G protein
    • Hernandez-Munoz I, de la Torre P, Sanchez-Alcazar JA, et al. Tumor necrosis factor alpha inhibits collagen alpha 1(I) gene expression in rat hepatic stellate cells through a G protein. Gastroenterology 1997;113:625-640
    • (1997) Gastroenterology , vol.113 , pp. 625-640
    • Hernandez-Munoz, I.1    De La Torre, P.2    Sanchez-Alcazar, J.A.3
  • 87
    • 0030998255 scopus 로고    scopus 로고
    • Induction of neutrophil-attracting chemokines in transforming rat hepatic stellate cells
    • Sprenger H, Kaufmann A, Garn H, et al. Induction of neutrophil-attracting chemokines in transforming rat hepatic stellate cells. Gastroenterology 1997;113:277-285
    • (1997) Gastroenterology , vol.113 , pp. 277-285
    • Sprenger, H.1    Kaufmann, A.2    Garn, H.3
  • 88
    • 0031596596 scopus 로고    scopus 로고
    • Blocking NF-kappaB in the liver: The good and bad news
    • Taub R. Blocking NF-kappaB in the liver: The good and bad news [editorial; comment]. Hepatology 1998;27:1445-1446
    • (1998) Hepatology , vol.27 , pp. 1445-1446
    • Taub, R.1
  • 89
    • 0031596594 scopus 로고    scopus 로고
    • Inhibition of NFkappaB in activated rat hepatic stellate cells by proteasome inhibitors and an IkappaB super-repressor
    • Hellerbrand C, Jobin C, Iimuro Y, Licato L, Sartor RB, Brenner DA. Inhibition of NFkappaB in activated rat hepatic stellate cells by proteasome inhibitors and an IkappaB super-repressor [see comments]. Hepatology 1998;27:1285-1295
    • (1998) Hepatology , vol.27 , pp. 1285-1295
    • Hellerbrand, C.1    Jobin, C.2    Iimuro, Y.3    Licato, L.4    Sartor, R.B.5    Brenner, D.A.6
  • 90
    • 0029665279 scopus 로고    scopus 로고
    • Expression of intracellular adhesion molecule 1 by activated hepatic stellate cells
    • Hellerbrand, Wang SC, Tsukamoto H, et al. Expression of intracellular adhesion molecule 1 by activated hepatic stellate cells. Hepatology 1996;24:670-676
    • (1996) Hepatology , vol.24 , pp. 670-676
    • Wang, S.C.1    Tsukamoto, H.2
  • 91
    • 0031575922 scopus 로고    scopus 로고
    • Regulation by cAMP of STAT2 activation in hepatic stellate cells
    • Kawada N, Uoya M, Seki S, et al. Regulation by cAMP of STAT2 activation in hepatic stellate cells. Biochem Biophys Res Commun 1997;233:464-469
    • (1997) Biochem Biophys Res Commun , vol.233 , pp. 464-469
    • Kawada, N.1    Uoya, M.2    Seki, S.3
  • 92
    • 0029097265 scopus 로고
    • Sp1 binding activity increases in activated Ito cells
    • Rippe RA, Almounajed G, Brenner DA. Sp1 binding activity increases in activated Ito cells. Hepatology 1995;22:241-251
    • (1995) Hepatology , vol.22 , pp. 241-251
    • Rippe, R.A.1    Almounajed, G.2    Brenner, D.A.3
  • 93
    • 0030858905 scopus 로고    scopus 로고
    • Early genes induced in hepatic stellate cells during wound healing
    • Lalazar A, Wong L, Yamasaki G, Friedman SL. Early genes induced in hepatic stellate cells during wound healing. Gene 1997;195:235-243
    • (1997) Gene , vol.195 , pp. 235-243
    • Lalazar, A.1    Wong, L.2    Yamasaki, G.3    Friedman, S.L.4
  • 94
    • 0030960781 scopus 로고    scopus 로고
    • A novel human zinc finger protein that interacts with the core promoter element of a TATA box-less gene
    • Koritschoner NP, Bocco JL, Panzetta-Dutari GM, et al. A novel human zinc finger protein that interacts with the core promoter element of a TATA box-less gene. J Biol Chem 1997;272: 9573-9580
    • (1997) J Biol Chem , vol.272 , pp. 9573-9580
    • Koritschoner, N.P.1    Bocco, J.L.2    Panzetta-Dutari, G.M.3
  • 95
    • 0032482952 scopus 로고    scopus 로고
    • Zf9, a Kruppel-like transcription factor upregulated in vivo during early hepatic fibrosis
    • Ratziu V, Lalazar A, Wong L, et al. Zf9, a Kruppel-like transcription factor upregulated in vivo during early hepatic fibrosis. Proc Natl Acad Sci USA 1998;95:9500-9505
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9500-9505
    • Ratziu, V.1    Lalazar, A.2    Wong, L.3
  • 96
    • 0032509217 scopus 로고    scopus 로고
    • Transcriptional activation of TGFbeta1 and its receptors by the Kruppel-like factor Zf9/CPBP and Sp1; potential mechanisms for autocrine fibrogenesis in response to injury
    • Kim Y, Ratziu V, Choi S-G, et al. Transcriptional activation of TGFbeta1 and its receptors by the Kruppel-like factor Zf9/CPBP and Sp1; potential mechanisms for autocrine fibrogenesis in response to injury. J Biol Chem 1998;273:33750-33758
    • (1998) J Biol Chem , vol.273 , pp. 33750-33758
    • Kim, Y.1    Ratziu, V.2    Choi, S.-G.3
  • 97
    • 0032577051 scopus 로고    scopus 로고
    • The Croonian Lecture 1997. The phosphorylation of proteins on tyrosine: Its role in cell growth and disease
    • Hunter T. The Croonian Lecture 1997. The phosphorylation of proteins on tyrosine: Its role in cell growth and disease. Philos Trans R Soc Lond B Biol Sci 1998;353:583-605
    • (1998) Philos Trans R Soc Lond B Biol Sci , vol.353 , pp. 583-605
    • Hunter, T.1
  • 98
    • 0032524350 scopus 로고    scopus 로고
    • Autoregulatory mechanisms in protein-tyrosine kinases
    • Hubbard SR, Mohammadi M, Schlessinger J. Autoregulatory mechanisms in protein-tyrosine kinases. J Biol Chem 1998;273: 11987-11990
    • (1998) J Biol Chem , vol.273 , pp. 11987-11990
    • Hubbard, S.R.1    Mohammadi, M.2    Schlessinger, J.3
  • 99
    • 0028140282 scopus 로고
    • Expression of platelet-derived growth factor in a model of acute liver injury
    • Pinzani M, Milani S, Grappone C, et al. Expression of platelet-derived growth factor in a model of acute liver injury. Hepatology 1994;19:701-707
    • (1994) Hepatology , vol.19 , pp. 701-707
    • Pinzani, M.1    Milani, S.2    Grappone, C.3
  • 100
    • 0031004620 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase is required for platelet-derived growth factor's actions on hepatic stellate cells
    • Marra F, Gentilini A, Pinzani M, et al. Phosphatidylinositol 3-kinase is required for platelet-derived growth factor's actions on hepatic stellate cells [see comments]. Gastroenterology 1997; 112:1297-1306
    • (1997) Gastroenterology , vol.112 , pp. 1297-1306
    • Marra, F.1    Gentilini, A.2    Pinzani, M.3
  • 101
    • 0028855914 scopus 로고    scopus 로고
    • The mitogenic effect of platelet-derived growth factor in human hepatic stellate cells requires calcium influx
    • Failli P, Ruocco C, De FR, et al. The mitogenic effect of platelet-derived growth factor in human hepatic stellate cells requires calcium influx. Am J Physiol 1995:C1133-1139
    • Am J Physiol , vol.1995
    • Failli, P.1    Ruocco, C.2    De, F.R.3
  • 102
    • 0030841159 scopus 로고    scopus 로고
    • Characterization of ion transport mechanisms regulating intracellular pH in hepatic stellate cells
    • Di Sario A, Baroni GS, Bendia E, et al. Characterization of ion transport mechanisms regulating intracellular pH in hepatic stellate cells. Am J Physiol 1997;273:G39-48
    • (1997) Am J Physiol , vol.273
    • Di Sario, A.1    Baroni, G.S.2    Bendia, E.3
  • 103
    • 0032574605 scopus 로고    scopus 로고
    • 2+ exchanger emerges in hepatic stellate cells after activation in association with liver fibrosis
    • 2+ exchanger emerges in hepatic stellate cells after activation in association with liver fibrosis. Proc Natl Acad Sci USA 1998;95:5389-5394
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 5389-5394
    • Nakamura, T.1    Arii, S.2    Monden, K.3
  • 104
    • 0030934866 scopus 로고    scopus 로고
    • Proliferation of hepatic stellate cells is inhibited by phosphorylation of CREB on serine 133
    • Houglum K, Lee KS, Chojkier M. Proliferation of hepatic stellate cells is inhibited by phosphorylation of CREB on serine 133. J Clin Invest 1997;99:1322-1328
    • (1997) J Clin Invest , vol.99 , pp. 1322-1328
    • Houglum, K.1    Lee, K.S.2    Chojkier, M.3
  • 105
    • 0031916189 scopus 로고    scopus 로고
    • Cellular localization of endothelin-1 and increased production in liver injury in the rat: Potential for autocrine and paracrine effects on stellate cells
    • Rockey DC, Fouassier L, Chung JJ, et al. Cellular localization of endothelin-1 and increased production in liver injury in the rat: Potential for autocrine and paracrine effects on stellate cells. Hepatology 1998;27:472-480
    • (1998) Hepatology , vol.27 , pp. 472-480
    • Rockey, D.C.1    Fouassier, L.2    Chung, J.J.3
  • 106
    • 0030059990 scopus 로고    scopus 로고
    • Endothelin I is overexpressed in human cirrhotic liver and exerts multiple effects on activated hepatic stellate cells
    • Pinzani M, Milani S, De Franco R, et al. Endothelin I is overexpressed in human cirrhotic liver and exerts multiple effects on activated hepatic stellate cells. Gastroenterology 1996;110: 534-548
    • (1996) Gastroenterology , vol.110 , pp. 534-548
    • Pinzani, M.1    Milani, S.2    De Franco, R.3
  • 107
    • 0029612273 scopus 로고
    • Action of endothelins on hepatic stellate cells
    • Kawada N, Kuroki T, Kobayashi K, et al. Action of endothelins on hepatic stellate cells. J Gastroenterol 1995;30:731-738
    • (1995) J Gastroenterol , vol.30 , pp. 731-738
    • Kawada, N.1    Kuroki, T.2    Kobayashi, K.3
  • 108
    • 3142635537 scopus 로고    scopus 로고
    • Growth inhibitory properties of endothelin-1 in activated human hepatic stellate cells: A cyclic adenosine monophosphate-mediated pathway. Inhibition of both extracellular signal-regulated kinase and c-Jun kinase and upregulation of endothrlin B receptors
    • Mallat A, Preaux AM, Serradeil-Le Gal C, et al. Growth inhibitory properties of endothelin-1 in activated human hepatic stellate cells: A cyclic adenosine monophosphate-mediated pathway. Inhibition of both extracellular signal-regulated kinase and c-Jun kinase and upregulation of endothrlin B receptors. J Clin Invest 1996;98:2771-2778
    • (1996) J Clin Invest , vol.98 , pp. 2771-2778
    • Mallat, A.1    Preaux, A.M.2    Serradeil-Le Gal, C.3
  • 109
    • 0029098308 scopus 로고
    • Thrombin stimulates proliferation of liver fat-storing cells and expression of monocyte chemotactic protein-1 : Potential role in liver injury
    • Marra F, Grandaliano G, Valente AJ, Abboud HE. Thrombin stimulates proliferation of liver fat-storing cells and expression of monocyte chemotactic protein-1 : Potential role in liver injury. Hepatology 1995;22:780-787
    • (1995) Hepatology , vol.22 , pp. 780-787
    • Marra, F.1    Grandaliano, G.2    Valente, A.J.3    Abboud, H.E.4
  • 110
    • 0028804232 scopus 로고
    • Fibroblast growth factor 2 and transforming growth factor beta 1 interactions in human liver myofibroblasts
    • Rosenbaum J, Blazejewski S, Preaux AM, et al. Fibroblast growth factor 2 and transforming growth factor beta 1 interactions in human liver myofibroblasts. Gastroenterology 1995; 109:1986-1996
    • (1995) Gastroenterology , vol.109 , pp. 1986-1996
    • Rosenbaum, J.1    Blazejewski, S.2    Preaux, A.M.3
  • 111
    • 0030830203 scopus 로고    scopus 로고
    • Insulin-like growth factors stimulate expression of hepatocyte growth factor hut not transforming growth factor beta1 in cultured hepatic stellate cells
    • Skrtic S, Wallenius V, Ekberg S, et al. Insulin-like growth factors stimulate expression of hepatocyte growth factor hut not transforming growth factor beta1 in cultured hepatic stellate cells. Endocrinology 1997;138:4683-4689
    • (1997) Endocrinology , vol.138 , pp. 4683-4689
    • Skrtic, S.1    Wallenius, V.2    Ekberg, S.3
  • 112
    • 0025043870 scopus 로고
    • Secretion of insulin-like growth factor-I and binding proteins by rat liver fat-storing cells: Regulatory role of platelet-derived growth factor
    • Pinzani M, Abboud HE, Aron DC. Secretion of insulin-like growth factor-I and binding proteins by rat liver fat-storing cells: Regulatory role of platelet-derived growth factor. Endocrinology 1990;127:2343-2349
    • (1990) Endocrinology , vol.127 , pp. 2343-2349
    • Pinzani, M.1    Abboud, H.E.2    Aron, D.C.3
  • 113
    • 0027264871 scopus 로고
    • Cell-specific expression of hepatocyte growth factor in liver. Upregulation in sinusoidal endothelial cells after carbon tetrachloride
    • Maher JJ. Cell-specific expression of hepatocyte growth factor in liver. Upregulation in sinusoidal endothelial cells after carbon tetrachloride. J Clin Invest 1993;91:2244-2252
    • (1993) J Clin Invest , vol.91 , pp. 2244-2252
    • Maher, J.J.1
  • 114
    • 0031058607 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 induces activation of Ras, Raf-1, MEK and MAPK in rat hepatic stellate cells
    • Reimann T, Hempel U, Krautwald S, et al. Transforming growth factor-beta1 induces activation of Ras, Raf-1, MEK and MAPK in rat hepatic stellate cells. FEBS Lett 1997;403:57-60
    • (1997) FEBS Lett , vol.403 , pp. 57-60
    • Reimann, T.1    Hempel, U.2    Krautwald, S.3
  • 115
    • 0031048333 scopus 로고    scopus 로고
    • Down-regulation of matrix and beta-PDGF receptor gene expression by anti-TGFbeta antibody in rat hepatic stellate cells during experimental liver injury
    • Ankoma-Sey V, Tzagarakis C, Chang KB, Friedman SL. Down-regulation of matrix and beta-PDGF receptor gene expression by anti-TGFbeta antibody in rat hepatic stellate cells during experimental liver injury. Int Hepatol Commun 1997;6:144-152
    • (1997) Int Hepatol Commun , vol.6 , pp. 144-152
    • Ankoma-Sey, V.1    Tzagarakis, C.2    Chang, K.B.3    Friedman, S.L.4
  • 116
    • 0029024768 scopus 로고
    • Regulation of Ito cell proliferation by soluble factors
    • Rosenbaum J, Blazejewski S. Regulation of Ito cell proliferation by soluble factors. J Hepatol 1995;22:65-70
    • (1995) J Hepatol , vol.22 , pp. 65-70
    • Rosenbaum, J.1    Blazejewski, S.2
  • 117
    • 0031012401 scopus 로고    scopus 로고
    • The cellular pathogenesis of portal hypertension: Stellate cell contractility, endothelin, and nitric oxide
    • Rockey DC. The cellular pathogenesis of portal hypertension: Stellate cell contractility, endothelin, and nitric oxide. Hepatology 1997;25:2-5
    • (1997) Hepatology , vol.25 , pp. 2-5
    • Rockey, D.C.1
  • 118
    • 0029891589 scopus 로고    scopus 로고
    • Endothelin induced contractility of stellate cells from normal and cirrhotic rat liver: Implications for regulation of portal pressure and resistance
    • Rockey DC, Weisiger RA. Endothelin induced contractility of stellate cells from normal and cirrhotic rat liver: Implications for regulation of portal pressure and resistance. Hepatology 1996; 24:233-240
    • (1996) Hepatology , vol.24 , pp. 233-240
    • Rockey, D.C.1    Weisiger, R.A.2
  • 119
    • 0028892827 scopus 로고
    • Chronic ethanol consumption increases hepatic sinusoidal contractile response to endothelin-1 in the rat
    • Bauer M, Paquette NC, Zhang JX, et al. Chronic ethanol consumption increases hepatic sinusoidal contractile response to endothelin-1 in the rat. Hepatology 1995;22:1565-1576
    • (1995) Hepatology , vol.22 , pp. 1565-1576
    • Bauer, M.1    Paquette, N.C.2    Zhang, J.X.3
  • 120
    • 0030795418 scopus 로고    scopus 로고
    • Arginine vasopressin induces contraction and stimulates growth of cultured human hepatic stellate cells
    • Bataller R, Nicolas JP, Gines P, et al. Arginine vasopressin induces contraction and stimulates growth of cultured human hepatic stellate cells. Gastroenterology 1997;113:615-624
    • (1997) Gastroenterology , vol.113 , pp. 615-624
    • Bataller, R.1    Nicolas, J.P.2    Gines, P.3
  • 121
    • 0026764692 scopus 로고
    • Eicosanoid-mediated contractility of hepatic stellate cells
    • Kawada N, Klein H, Decker K. Eicosanoid-mediated contractility of hepatic stellate cells. Biochem J 1992;285:367-371
    • (1992) Biochem J , vol.285 , pp. 367-371
    • Kawada, N.1    Klein, H.2    Decker, K.3
  • 122
    • 0028027834 scopus 로고
    • Effect of adrenomedullin on hepatic pericytes (stellate cells) of the rat
    • Kawada N, Inoue M. Effect of adrenomedullin on hepatic pericytes (stellate cells) of the rat. FEBS Lett 1994;356:109-113
    • (1994) FEBS Lett , vol.356 , pp. 109-113
    • Kawada, N.1    Inoue, M.2
  • 123
    • 0028957207 scopus 로고
    • Inducible nitric oxide synthase in rat hepatic lipocytes and the effect of nitric oxide on lipocyte contractility
    • Rockey DC, Chung JJ. Inducible nitric oxide synthase in rat hepatic lipocytes and the effect of nitric oxide on lipocyte contractility. J Clin Invest 1995;95:1199-1206
    • (1995) J Clin Invest , vol.95 , pp. 1199-1206
    • Rockey, D.C.1    Chung, J.J.2
  • 124
    • 0025855367 scopus 로고
    • Transforming growth factors beta 1 and alpha in chronic liver disease. Effects of interferon alfa therapy
    • Castilla A, Prieto J, Fausto N. Transforming growth factors beta 1 and alpha in chronic liver disease. Effects of interferon alfa therapy [see comments]. N Engl J Med 1991;324:933-940
    • (1991) N Engl J Med , vol.324 , pp. 933-940
    • Castilla, A.1    Prieto, J.2    Fausto, N.3
  • 125
    • 0029121317 scopus 로고
    • Molecular mechanisms of liver fibrogenesis - A homage to the role of activated fat-storing cells
    • Gressner AM, Bachem MG. Molecular mechanisms of liver fibrogenesis - A homage to the role of activated fat-storing cells. Digestion 1995;56:335-346
    • (1995) Digestion , vol.56 , pp. 335-346
    • Gressner, A.M.1    Bachem, M.G.2
  • 126
    • 0029159792 scopus 로고
    • Cell-specific expression of transforming growth factor-beta in vat liver. Evidence for autocrine regulation of hepatocyte proliferation
    • Bissell DM, Wang SS, Jarnagin WR, Roll FJ. Cell-specific expression of transforming growth factor-beta in vat liver. Evidence for autocrine regulation of hepatocyte proliferation. J Clin Invest 1995;96:447-455
    • (1995) J Clin Invest , vol.96 , pp. 447-455
    • Bissell, D.M.1    Wang, S.S.2    Jarnagin, W.R.3    Roll, F.J.4
  • 127
    • 0030771436 scopus 로고    scopus 로고
    • Multiple and essential Sp1 binding sites in the promoter for transforming growth factor-beta type I receptor
    • Ji C, Casinghino S, McCarthy TL, Centrella M. Multiple and essential Sp1 binding sites in the promoter for transforming growth factor-beta type I receptor. J Biol Chem 1997;272: 21260-21267
    • (1997) J Biol Chem , vol.272 , pp. 21260-21267
    • Ji, C.1    Casinghino, S.2    McCarthy, T.L.3    Centrella, M.4
  • 128
    • 0001528025 scopus 로고    scopus 로고
    • A key role for Zf9 in hepatic fibrosis via its transcriptional activation of TGFb1 and types I and II TGFb receptors genes in rat stellate cells
    • Abstract
    • Ratziu R, Kim SJ, Kim YS, et al. A key role for Zf9 in hepatic fibrosis via its transcriptional activation of TGFb1 and types I and II TGFb receptors genes in rat stellate cells. Hepatology 1997;26:185A( Abstract)
    • (1997) Hepatology , vol.26
    • Ratziu, R.1    Kim, S.J.2    Kim, Y.S.3
  • 129
    • 0031596123 scopus 로고    scopus 로고
    • Analysis of the expression pattern of the latent transforming growth factor beta binding protein isoforms in normal and diseased human liver reveals a new splice variant missing the proteinase-sensitive hinge region
    • Michel K, Roth S, Trautwein C, et al. Analysis of the expression pattern of the latent transforming growth factor beta binding protein isoforms in normal and diseased human liver reveals a new splice variant missing the proteinase-sensitive hinge region. Hepatology 1998;27:1592-1599
    • (1998) Hepatology , vol.27 , pp. 1592-1599
    • Michel, K.1    Roth, S.2    Trautwein, C.3
  • 130
    • 0032054574 scopus 로고    scopus 로고
    • Mads and Smads in TGF beta signalling
    • Attisano L, Wrana JL. Mads and Smads in TGF beta signalling. Curr Opin Cell Biol 1998;10:188-194
    • (1998) Curr Opin Cell Biol , vol.10 , pp. 188-194
    • Attisano, L.1    Wrana, J.L.2
  • 131
    • 0029842713 scopus 로고    scopus 로고
    • MAD-related proteins in TGF-beta signalling
    • Wrana JL, Attisano L. MAD-related proteins in TGF-beta signalling. Trends Genet 1996;12:493-496
    • (1996) Trends Genet , vol.12 , pp. 493-496
    • Wrana, J.L.1    Attisano, L.2
  • 132
    • 0031438047 scopus 로고    scopus 로고
    • TGF-beta signalling from cell membrane to nucleus through SMAD proteins
    • Heldin CH, Miyazono K, ten Dijke P. TGF-beta signalling from cell membrane to nucleus through SMAD proteins. Nature 1997;390:465-471
    • (1997) Nature , vol.390 , pp. 465-471
    • Heldin, C.H.1    Miyazono, K.2    Ten Dijke, P.3
  • 133
    • 0031134623 scopus 로고    scopus 로고
    • Cytokines modulate routes of collagen breakdown. Review with special emphasis on mechanisms of collagen degradation in the periodontium and the burst hypothesis of periodontal disease progression
    • van der Zee E, Everts V, Beertsen W. Cytokines modulate routes of collagen breakdown. Review with special emphasis on mechanisms of collagen degradation in the periodontium and the burst hypothesis of periodontal disease progression. J Clin Periodontal 1997;24:297-305
    • (1997) J Clin Periodontal , vol.24 , pp. 297-305
    • Van Der Zee, E.1    Everts, V.2    Beertsen, W.3
  • 134
    • 0030948502 scopus 로고    scopus 로고
    • The hepatic stellate (Ito) cell: Its role in human liver disease
    • Hautekeete ML, Geerts A. The hepatic stellate (Ito) cell: Its role in human liver disease. Virchows Arch 1997;430:195-207
    • (1997) Virchows Arch , vol.430 , pp. 195-207
    • Hautekeete, M.L.1    Geerts, A.2
  • 135
    • 0029310597 scopus 로고
    • Cytokine regulation of matrix metalloproteinase activity and its regulatory dysfunction in disease
    • Ries C, Petrides PE. Cytokine regulation of matrix metalloproteinase activity and its regulatory dysfunction in disease. Biol Chem Hoppe-Seyler 1995;376:345-355
    • (1995) Biol Chem Hoppe-Seyler , vol.376 , pp. 345-355
    • Ries, C.1    Petrides, P.E.2
  • 136
    • 0029064989 scopus 로고
    • Control of collagen deposition in mammalian lung
    • Bienkowski RS, Gotkin MG. Control of collagen deposition in mammalian lung. Proc Soc Exp Biol Med 1995;209:118-140
    • (1995) Proc Soc Exp Biol Med , vol.209 , pp. 118-140
    • Bienkowski, R.S.1    Gotkin, M.G.2
  • 137
    • 0027682714 scopus 로고
    • Contribution of sinusoidal endothelial liver cells to liver fibrosis: Expression of transforming growth factor-beta 1 receptors and modulation of plasmin-generating enzymes by transforming growth factor-beta 1
    • Rieder H, Armbrust T, Meyer zum Buschenfelde KH, Ramadori G. Contribution of sinusoidal endothelial liver cells to liver fibrosis: Expression of transforming growth factor-beta 1 receptors and modulation of plasmin-generating enzymes by transforming growth factor-beta 1. Hepatology 1993;18:937-944
    • (1993) Hepatology , vol.18 , pp. 937-944
    • Rieder, H.1    Armbrust, T.2    Meyer Zum Buschenfelde, K.H.3    Ramadori, G.4
  • 138
    • 0032934278 scopus 로고    scopus 로고
    • Monocyte chemotactic protein-1 as a chemoattractant for human hepatic stellate cells
    • Marra F, Romanelli RG, Pastacaldi S, et al. Monocyte chemotactic protein-1 as a chemoattractant for human hepatic stellate cells. Hepatology 1999;29:140-148
    • (1999) Hepatology , vol.29 , pp. 140-148
    • Marra, F.1    Romanelli, R.G.2    Pastacaldi, S.3
  • 139
    • 0031883173 scopus 로고    scopus 로고
    • Increased expression of monocyte chemotactic protein-1 during active hepatic fibrogenesis: Correlation with monocyte infiltration
    • Marra F, DeFranco R, Grappone C, et al. Increased expression of monocyte chemotactic protein-1 during active hepatic fibrogenesis: Correlation with monocyte infiltration. Am J Pathol 1998;152:423-430
    • (1998) Am J Pathol , vol.152 , pp. 423-430
    • Marra, F.1    DeFranco, R.2    Grappone, C.3
  • 140
    • 0027360267 scopus 로고
    • Cultured human liver fat-storing cells produce monocyte chemotactic protein-1. Regulation by proinflammatory cytokines
    • Marra F, Valente AJ, Pinzani M, Abboud HE. Cultured human liver fat-storing cells produce monocyte chemotactic protein-1. Regulation by proinflammatory cytokines. J Clin Invest 1993; 92:1674-1680
    • (1993) J Clin Invest , vol.92 , pp. 1674-1680
    • Marra, F.1    Valente, A.J.2    Pinzani, M.3    Abboud, H.E.4
  • 141
    • 0031559886 scopus 로고    scopus 로고
    • Integrin-mediated stimulation of monocyte chemotactic protein-1 expression
    • Marra F, Pastacaldi S, Romanelli RG, et al. Integrin-mediated stimulation of monocyte chemotactic protein-1 expression. FEBS Lett 1997;414:221-225
    • (1997) FEBS Lett , vol.414 , pp. 221-225
    • Marra, F.1    Pastacaldi, S.2    Romanelli, R.G.3
  • 142
    • 0030624780 scopus 로고    scopus 로고
    • New therapies for inflammatory bowel disease: An update on chimeric anti-TNF alpha antibodies and IL-10 therapy
    • van Hogezand RA, Verspaget HW. New therapies for inflammatory bowel disease: An update on chimeric anti-TNF alpha antibodies and IL-10 therapy. Scand J Gastroenterol 1997;223(suppl): 105-107
    • (1997) Scand J Gastroenterol , vol.223 , Issue.SUPPL. , pp. 105-107
    • Van Hogezand, R.A.1    Verspaget, H.W.2
  • 143
    • 0031769880 scopus 로고    scopus 로고
    • Primary rat and mouse hepatic stellate cells express the macrophage inhibitor cytokine interleukin 10 during the course of activation in vitro
    • Thompson KC, Trowern A, Fowell A, et al. Primary rat and mouse hepatic stellate cells express the macrophage inhibitor cytokine interleukin 10 during the course of activation in vitro. Hepatology 1998;28:1518-1524
    • (1998) Hepatology , vol.28 , pp. 1518-1524
    • Thompson, K.C.1    Trowern, A.2    Fowell, A.3
  • 144
    • 0031769883 scopus 로고    scopus 로고
    • Interleukin-10 expression and function in murine liver inflammation and fibrosis
    • in press
    • Thompson K, Maltby J, Fallowfield J, et al. Interleukin-10 expression and function in murine liver inflammation and fibrosis. Hepatology 1998;(in press)
    • (1998) Hepatology
    • Thompson, K.1    Maltby, J.2    Fallowfield, J.3
  • 145
    • 0029810790 scopus 로고    scopus 로고
    • Progressive liver injury in chronic hepatitis C infection correlates with increased intrahepatic expression of Th1-associated cytokines
    • Napoli J, Bishop GA, McGuinness PH, et al. Progressive liver injury in chronic hepatitis C infection correlates with increased intrahepatic expression of Th1-associated cytokines. Hepatology 1996;24:759-765
    • (1996) Hepatology , vol.24 , pp. 759-765
    • Napoli, J.1    Bishop, G.A.2    McGuinness, P.H.3
  • 146
    • 0027210834 scopus 로고
    • Retinol release by activated rat hepatic lipocytes: Regulation by Kupffer cell-conditioned medium and PDGF
    • Friedman SL, Wei S, Blaner WS, Retinol release by activated rat hepatic lipocytes: Regulation by Kupffer cell-conditioned medium and PDGF. Am J Physiol 1993;264:G947-G952
    • (1993) Am J Physiol , vol.264
    • Friedman, S.L.1    Wei, S.2    Blaner, W.S.3
  • 147
    • 0033032033 scopus 로고    scopus 로고
    • Increased 9,13-di-cis-retinoic acid in rat hepatic fibrosis: A potential link between retinoid loss and TGF-β mediated fibrogenesis via RARa activation
    • in press
    • Okuno M, Sato T, Kitamoto T, et al. Increased 9,13-di-cis-retinoic acid in rat hepatic fibrosis: A potential link between retinoid loss and TGF-β mediated fibrogenesis via RARa activation. J Hepatol 1999; in press
    • (1999) J Hepatol
    • Okuno, M.1    Sato, T.2    Kitamoto, T.3
  • 148
    • 0031948431 scopus 로고    scopus 로고
    • (Latent) transforming growth factor beta in liver parenchymal cells, its injury-dependent release, and paracrine effects on rat hepatic stellate cells
    • Roth S, Michel K, Gressner AM. (Latent) transforming growth factor beta in liver parenchymal cells, its injury-dependent release, and paracrine effects on rat hepatic stellate cells. Hepatology 1998;27:1003-1012
    • (1998) Hepatology , vol.27 , pp. 1003-1012
    • Roth, S.1    Michel, K.2    Gressner, A.M.3
  • 149
    • 0033515099 scopus 로고    scopus 로고
    • Blockade of type beta transforming growth factor signaling prevents liver fibrosis and dysfunction in the rat
    • Qi Z, Atsuchi N, Ooshima A, Takeshita A, Ueno H. Blockade of type beta transforming growth factor signaling prevents liver fibrosis and dysfunction in the rat [In Process Citation). Proc Natl Acad Sci USA 1999;96:2345-2349
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 2345-2349
    • Qi, Z.1    Atsuchi, N.2    Ooshima, A.3    Takeshita, A.4    Ueno, H.5
  • 150
    • 0030716183 scopus 로고    scopus 로고
    • Antibodies to tumor necrosis factor alfa attenuate hepatic necrosis and inflammation caused by chronic exposure to ethanol in the rat
    • Iimuro Y, Gallucci RM, Luster MI, Kono H, Thurman RG. Antibodies to tumor necrosis factor alfa attenuate hepatic necrosis and inflammation caused by chronic exposure to ethanol in the rat. Hepatology 1997;26:1530-1537
    • (1997) Hepatology , vol.26 , pp. 1530-1537
    • Iimuro, Y.1    Gallucci, R.M.2    Luster, M.I.3    Kono, H.4    Thurman, R.G.5
  • 151
    • 0028891495 scopus 로고
    • Endothelin and endothelin antagonists: Pharmacology and clinical implications
    • Luscher TF, Wenzel RR. Endothelin and endothelin antagonists: Pharmacology and clinical implications. Agents Actions 1995; 45(suppl):237-253
    • (1995) Agents Actions , vol.45 , Issue.SUPPL. , pp. 237-253
    • Luscher, T.F.1    Wenzel, R.R.2
  • 152
    • 0029766854 scopus 로고    scopus 로고
    • Endothelin antagonism in experimental hepatic fibrosis. Implications for endothelin in the pathogenesis of wound healing
    • Rockey DC, Chung JJ. Endothelin antagonism in experimental hepatic fibrosis. Implications for endothelin in the pathogenesis of wound healing. J Clin Invest 1996;98:1381-1388
    • (1996) J Clin Invest , vol.98 , pp. 1381-1388
    • Rockey, D.C.1    Chung, J.J.2
  • 153
    • 0031887743 scopus 로고    scopus 로고
    • Protein kinase inhibitors: The tyrosine-specific protein kinases
    • Lawrence DS, Niu J. Protein kinase inhibitors: The tyrosine-specific protein kinases. Pharmacol Ther 1998;77:81-114
    • (1998) Pharmacol Ther , vol.77 , pp. 81-114
    • Lawrence, D.S.1    Niu, J.2
  • 154
    • 0031031973 scopus 로고    scopus 로고
    • Therapeutic approaches to organ fibrosis
    • Franklin TJ. Therapeutic approaches to organ fibrosis. Int J Biochem Cell Biol 1997;29:79-89
    • (1997) Int J Biochem Cell Biol , vol.29 , pp. 79-89
    • Franklin, T.J.1
  • 155
    • 6844266294 scopus 로고    scopus 로고
    • Safety and pharmacokinetics of recombinant human relaxin in systemic sclerosis
    • Seibold JR, Clements PJ, Furst DE, et al. Safety and pharmacokinetics of recombinant human relaxin in systemic sclerosis. J Rheumatol 1998;25:302-307
    • (1998) J Rheumatol , vol.25 , pp. 302-307
    • Seibold, J.R.1    Clements, P.J.2    Furst, D.E.3
  • 156
    • 0026782189 scopus 로고
    • Inhibition of hepatic lipocyte activation in culture by interferon-gamma
    • Rockey DC, Maher JJ, Jarnagin WR, et al. Inhibition of hepatic lipocyte activation in culture by interferon-gamma. Hepatology 1992;16:776-778
    • (1992) Hepatology , vol.16 , pp. 776-778
    • Rockey, D.C.1    Maher, J.J.2    Jarnagin, W.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.